Quantitative Genetics, Heritability, and Variances
Жүктеу.....
Пікірлер: 52
@sgb5234 жыл бұрын
This helps me a lot to understand the foundation of quantitative genetics, especially now we're in a remote learning setting in the university. This is a great supplemental material! Thank you, Sir Thomas!
@eddylikhuleni20474 жыл бұрын
Its been a long time not understanding this thing, but after your video i now understand it clear. You are the best teacher
@rogersakatwijuka98044 жыл бұрын
Excellent piece of work, well explained and illustrated. Thank you and more blessings to you.
@joaquimsantos94254 жыл бұрын
Great video!!!! Thanks for sharing it!
@isaiaskunz20173 жыл бұрын
I wish my univercity professors were half as good as you are teaching. Thanks a lot
@rounakkumar62593 жыл бұрын
Simply explained ....&.fully clearing the concept.. thanks for the video
@poleipaladra3472 жыл бұрын
Thank you for the clear explanation Mr. Mennella! I was wondering: How is variation explained by epigenetic modification accounted for?
@sidi11283 жыл бұрын
Thank you so much for this clear and concise explanation!
@ritikachatterjee16902 жыл бұрын
Amazing video... explained in such simple manner.Really helpful 👍
@weevilknievel32005 жыл бұрын
This was really simple and helpful, thank you!
@tisaloewen70513 жыл бұрын
this is the best video hands down on the subject on youtube
@abozuraborish3783 жыл бұрын
thanks alot for helping us .... keep going
@aavashshrestha55752 жыл бұрын
Thanks a lot for making this video. Much appreciated👍👍👍
@izzywang706011 ай бұрын
This video was a godsend, thank you for explaining variance so clearly!
@leinaessakalli95414 жыл бұрын
very clear video thank you soooo much
@muhammetnazar17544 жыл бұрын
You are the best TEACHER.!!! THANKS FOR YOUR GREAT GREAT LECTURES ....
@muhammetnazar1754
4 жыл бұрын
@@thomasmennella5501 sır, I am studying genetics , my professors can not explain clearly lectures , sır keep going. We need teachers like you.
@Ice84letters Жыл бұрын
really good video, explains very well how the genetic variants works
@thomasmennella5501
Жыл бұрын
Thanks, Irene! Much appreciated!
@nashiehun91416 жыл бұрын
you teach so well
@Hawthornphobia5 ай бұрын
thank u so much...way better than my prof
@faithfathi59926 жыл бұрын
Do you have blog?
@aavashadhikari93925 жыл бұрын
help me to built a concept on different types of variance.
@gens80944 жыл бұрын
Nicely explained
@rub80464 жыл бұрын
What about gene-environment interaction?
@kritika13154 жыл бұрын
This video saved the day. You've explained everything with great clarity. Thank you.
@parihars28499 ай бұрын
This is wonderful...Noone taught us like this before. U have done a wonderful job by sharing this on utube
@thomasmennella5501
9 ай бұрын
Thank you very much. I greatly appreciate the kind words.
@shwetaparmar67422 жыл бұрын
Thankyou so much. it really helped ❤️
@kasseecraft72303 жыл бұрын
Thank you!
@christinalrichards5 ай бұрын
I love this! Thanks! What about the parent offspring regression though? When you argue that the farmers focus on additive variance because its more predictable it doesn't explain why the regression approach works.
@malihatunnesa39723 жыл бұрын
Thanks a lot !
@ApiaryManager4 жыл бұрын
Thank you. An excellent explanation of Honeybee genetics!
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 If you are ever looking for a real world example of this being used in a haplo-diploid breeding programme, take a look at www.beebreed.eu
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 I appreciate your efforts in producing all of this material. Believe it, or not, I enjoyed your lectures so much that I went out and bought the book so I could follow along! :-D
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 I enjoyed your lectures very much. Your knowledge and enthusiasm are so infectious that it's difficult not to be interested! I'm not alone either. I see so many comments extolling your ability to convey the subject in both a simple and rational manner. Thanks again!
@yohanneseshetu42684 жыл бұрын
Hello Sir, I am Yohannes form Ethiopia, I need your help on how to calculate heritability and genetic advance for Augmented design, because only checks are repeated in the experiments. I used Proc mixed model in SAS, in the 1st run, treat as fixed and block as random.while in the 2nd run treat partitioned to test genotypes (as random) and checks (fixed) to produce BLUP. Please, sir, I need your kind guidance to estimate heritability and genetic advance to complete my experiment (it is single trial, 225 testing genotypes,with 5 check and 5 block). I hope your response is soon!
@saikiranveldandi952 жыл бұрын
could you please explain about negative heritability
@parihars28499 ай бұрын
Why does the book says that only the additive gentic variance is heritable type and not the dominant and epistatic variance?
@thomasmennella5501
9 ай бұрын
It’s not that only additive genetic variance is heritable, but instead that AGV is the most useful for hereditary studies and breeding. With additive genes, each allele contributes to the phenotype additively and equally. So AA has twice as much phenotype as Aa, and aa lacks the trait. For this reason, a breeder can always deduce the genotype by looking at the phenotype. This makes additive genes the most useful for breeding - no ambiguity. But to your point, all of the variances are genetically based and therefore all are inheritable.
@Modi20202 жыл бұрын
Excellent work and video. I only noticed you pronounce it hetribility instead of heritability.
@tinayang73515 жыл бұрын
I do not understand why the dgv could be confusing for breeders. It can be very precisely viewed as well.
@hugodelin4304
5 жыл бұрын
well if you breed and A is big and a is small but all your cows are Aa they look like they are AA but arent so when the next generation comes around they are confused when some aa pop out. Sorry for broken English not first language
@autumnclouds20944 жыл бұрын
Great lecture thank you . Any numbers about respective percentages of role of environment / genes in human intelligence ?
@boydhooper40808 ай бұрын
We should stick to the well recognised established terminology. In Biology and genetics a complex trait is controlled by many genes. It is polygenic. If it’s controlled / influenced by other factors like the environment, then it is a multifactorial trait. Don’t use the term complex trait to mean anything other than polygenic trait otherwise we’re going to have confusion.
@skepticmafia2 жыл бұрын
16:00 blue
@skepticmafia
2 жыл бұрын
17:00 blue
@skepticmafia
2 жыл бұрын
21:01 blue
@hookem37684 жыл бұрын
Please write your capital A's more legibly!
@rumibeatz48223 ай бұрын
8:02 whether you are homeless I gotta comment, or heterozygotic...
@thomasmennella5501
3 ай бұрын
LOL. It does sound like “homeless I gotta comment”. Oh, man… 🤦♂️
@TheCatarrh2 жыл бұрын
I see people are grateful for this video. I suppose thats good. I found it annoying with the ads and the crappy graphics. But maybe if I gave it a chance and actually listened to it, i would have found it worthwhile. Who knows.
Пікірлер: 52
This helps me a lot to understand the foundation of quantitative genetics, especially now we're in a remote learning setting in the university. This is a great supplemental material! Thank you, Sir Thomas!
Its been a long time not understanding this thing, but after your video i now understand it clear. You are the best teacher
Excellent piece of work, well explained and illustrated. Thank you and more blessings to you.
Great video!!!! Thanks for sharing it!
I wish my univercity professors were half as good as you are teaching. Thanks a lot
Simply explained ....&.fully clearing the concept.. thanks for the video
Thank you for the clear explanation Mr. Mennella! I was wondering: How is variation explained by epigenetic modification accounted for?
Thank you so much for this clear and concise explanation!
Amazing video... explained in such simple manner.Really helpful 👍
This was really simple and helpful, thank you!
this is the best video hands down on the subject on youtube
thanks alot for helping us .... keep going
Thanks a lot for making this video. Much appreciated👍👍👍
This video was a godsend, thank you for explaining variance so clearly!
very clear video thank you soooo much
You are the best TEACHER.!!! THANKS FOR YOUR GREAT GREAT LECTURES ....
@muhammetnazar1754
4 жыл бұрын
@@thomasmennella5501 sır, I am studying genetics , my professors can not explain clearly lectures , sır keep going. We need teachers like you.
really good video, explains very well how the genetic variants works
@thomasmennella5501
Жыл бұрын
Thanks, Irene! Much appreciated!
you teach so well
thank u so much...way better than my prof
Do you have blog?
help me to built a concept on different types of variance.
Nicely explained
What about gene-environment interaction?
This video saved the day. You've explained everything with great clarity. Thank you.
This is wonderful...Noone taught us like this before. U have done a wonderful job by sharing this on utube
@thomasmennella5501
9 ай бұрын
Thank you very much. I greatly appreciate the kind words.
Thankyou so much. it really helped ❤️
Thank you!
I love this! Thanks! What about the parent offspring regression though? When you argue that the farmers focus on additive variance because its more predictable it doesn't explain why the regression approach works.
Thanks a lot !
Thank you. An excellent explanation of Honeybee genetics!
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 If you are ever looking for a real world example of this being used in a haplo-diploid breeding programme, take a look at www.beebreed.eu
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 I appreciate your efforts in producing all of this material. Believe it, or not, I enjoyed your lectures so much that I went out and bought the book so I could follow along! :-D
@ApiaryManager
4 жыл бұрын
@@thomasmennella5501 I enjoyed your lectures very much. Your knowledge and enthusiasm are so infectious that it's difficult not to be interested! I'm not alone either. I see so many comments extolling your ability to convey the subject in both a simple and rational manner. Thanks again!
Hello Sir, I am Yohannes form Ethiopia, I need your help on how to calculate heritability and genetic advance for Augmented design, because only checks are repeated in the experiments. I used Proc mixed model in SAS, in the 1st run, treat as fixed and block as random.while in the 2nd run treat partitioned to test genotypes (as random) and checks (fixed) to produce BLUP. Please, sir, I need your kind guidance to estimate heritability and genetic advance to complete my experiment (it is single trial, 225 testing genotypes,with 5 check and 5 block). I hope your response is soon!
could you please explain about negative heritability
Why does the book says that only the additive gentic variance is heritable type and not the dominant and epistatic variance?
@thomasmennella5501
9 ай бұрын
It’s not that only additive genetic variance is heritable, but instead that AGV is the most useful for hereditary studies and breeding. With additive genes, each allele contributes to the phenotype additively and equally. So AA has twice as much phenotype as Aa, and aa lacks the trait. For this reason, a breeder can always deduce the genotype by looking at the phenotype. This makes additive genes the most useful for breeding - no ambiguity. But to your point, all of the variances are genetically based and therefore all are inheritable.
Excellent work and video. I only noticed you pronounce it hetribility instead of heritability.
I do not understand why the dgv could be confusing for breeders. It can be very precisely viewed as well.
@hugodelin4304
5 жыл бұрын
well if you breed and A is big and a is small but all your cows are Aa they look like they are AA but arent so when the next generation comes around they are confused when some aa pop out. Sorry for broken English not first language
Great lecture thank you . Any numbers about respective percentages of role of environment / genes in human intelligence ?
We should stick to the well recognised established terminology. In Biology and genetics a complex trait is controlled by many genes. It is polygenic. If it’s controlled / influenced by other factors like the environment, then it is a multifactorial trait. Don’t use the term complex trait to mean anything other than polygenic trait otherwise we’re going to have confusion.
16:00 blue
@skepticmafia
2 жыл бұрын
17:00 blue
@skepticmafia
2 жыл бұрын
21:01 blue
Please write your capital A's more legibly!
8:02 whether you are homeless I gotta comment, or heterozygotic...
@thomasmennella5501
3 ай бұрын
LOL. It does sound like “homeless I gotta comment”. Oh, man… 🤦♂️
I see people are grateful for this video. I suppose thats good. I found it annoying with the ads and the crappy graphics. But maybe if I gave it a chance and actually listened to it, i would have found it worthwhile. Who knows.