Pulmonary Function Tests (PFTs) | Clinical Medicine

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Ninja Nerds!
Professor Zach Murphy will be presenting on Pulmonary Function Tests (PFTs).
Pulmonary Function Tests (PFTs) are a set of non-invasive diagnostic tests used to evaluate lung function. These tests measure multiple aspects of respiratory physiology, such as lung volume, flow rates, and gas exchange, providing valuable data for diagnosing, managing, and monitoring various respiratory diseases, including obstructive and restrictive lung diseases.
What Tests Do PFTs Include?
1. Spirometry: This is the most common PFT and measures the amount and speed of air that can be inhaled and exhaled. Spirometry tests often include Forced Vital Capacity (FVC) and Forced Expiratory Volume in one second (FEV1).
2. Lung Volumes: Using techniques like body plethysmography, these tests measure various components of lung volumes like the Total Lung Capacity (TLC), Residual Volume (RV), and Functional Residual Capacity (FRC).
3. Diffusion Capacity of the Lung for Carbon Monoxide (DLCO): This test measures how efficiently gas is transferred from the lungs into the blood.
4. Bronchial Challenge Test: Also known as bronchoprovocation, this test assesses airway hyperresponsiveness, often using agents like methacholine or histamine.
5. Arterial Blood Gases (ABG): While not strictly a PFT, ABGs can complement the data by providing information on blood pH, CO2, and O2 levels, which are indicators of gas exchange efficiency.
In summary, PFTs provide a comprehensive evaluation of lung function that is essential for the diagnosis, management, and monitoring of both restrictive and obstructive lung diseases. Their importance in obstructive lung conditions lies in initial diagnosis, ongoing management, and prognostic assessment, making them an indispensable tool in modern respiratory medicine.
Table of Contents:
0:00 Lab
0:07 Pulmonary Function Tests (PFTs) Introduction
0:43 Lung Volumes (Plethysmography)
7:54 Forced Spirometry
12:10 Bronchodilator / Bronchoconstriction Tests
14:49 DLCO Testing
17:35 Diagnostic Approach
19:54 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Respiratory | Forced S...
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Пікірлер: 57

  • @aadhithkumarphysiotherapist01
    @aadhithkumarphysiotherapist013 ай бұрын

    Don't get death for atleast 500 years zach. Tonnes of Decades requires you ❤

  • @swastikakarki7221
    @swastikakarki72213 ай бұрын

    Literally you are the light of my medical life 😭♥️( thanks for being the bestest teacher ever )

  • @WasabiSniffer
    @WasabiSnifferАй бұрын

    some day, you'll be nominated for a Nobel Prize in medicine, for discovering an effective, succinct, and digestible way to teach medicine to aspiring and current doctors, PAs, nurses and technicians, and vicariously saving millions of lives...

  • @chiragkukadiya8866
    @chiragkukadiya88663 ай бұрын

    I usually do not comment on any videos. This is the first time you made you me to log in to my youtube account to just Thank you for explaining it such a easy way. You are the Legend. Hats off to you !

  • @RebecaCastro-zo6zk
    @RebecaCastro-zo6zk2 ай бұрын

    every single video I watch really helps me prepare for my lectures as well as review after. They are AWESOME. highly recommend the notes/subscription. I'm in CRNA school and it is a little bit less of a struggle with your help. Thank you!!!

  • @yavannapeet3952
    @yavannapeet39523 ай бұрын

    Just in time for my PFT exam! ❤ you guys!

  • @drsakshijoshi
    @drsakshijoshi2 ай бұрын

    Omg! Thank you so much. You simplified it really well ❤

  • @prosen813
    @prosen8132 ай бұрын

    You are a blessing!

  • @jihane4542
    @jihane45423 ай бұрын

    So helpful! Thank you!

  • @josemojica6419
    @josemojica64192 ай бұрын

    Thanks for the video!

  • @soumyadeepmaity8672
    @soumyadeepmaity8672Ай бұрын

    I just want to leave a comment for you ! Although you deserve even more , you are making students life ❤. I want to say thank you 😊 ❤ . Real hero who is helping costs infinity 😊

  • @katiaali2562
    @katiaali25623 ай бұрын

    this is great!! so much better than my prof teaching it!! I'm an RT student and would love it if you could do any videos about SABA, LAMA, SAMA, LABA, ICS meds

  • @Vimalkumar-zw2kk
    @Vimalkumar-zw2kk3 ай бұрын

    Great explanation 👏🏼❤

  • @pinkuzzz
    @pinkuzzzАй бұрын

    The great professor zach🙏

  • @mustafagazi-zy7br
    @mustafagazi-zy7br24 күн бұрын

    great explanation

  • @user-tj4bd1vs2d
    @user-tj4bd1vs2dКүн бұрын

    Thank you so much for the great video

  • @anantamia5627
    @anantamia5627Ай бұрын

    Thank you so much!!

  • @currentbees6759
    @currentbees67592 ай бұрын

    its just so so so good

  • @rj_rtz
    @rj_rtz2 ай бұрын

    The greatest alive♥️♥️

  • @carljohnson5778
    @carljohnson57782 ай бұрын

    I love this mannnnnn❤❤❤❤❤

  • @user-tz7sc3ey3k
    @user-tz7sc3ey3k2 ай бұрын

    Great job

  • @user-kp3ns1bv8j
    @user-kp3ns1bv8jАй бұрын

    Great bro,Thank you❤

  • @howraaal_shbanat
    @howraaal_shbanat3 ай бұрын

    You are a legend 💙💙

  • @rawaqasim9062
    @rawaqasim9062Ай бұрын

    Thank you

  • @KhadarMohamoud-jj5tw
    @KhadarMohamoud-jj5tw19 күн бұрын

    thank you ninja nerd

  • @karumbavai_kavithaigal
    @karumbavai_kavithaigalАй бұрын

    Thank you so much sir

  • @jackswinger8781
    @jackswinger87812 ай бұрын

    I will appreciate you forever

  • @Medperfect
    @Medperfect20 күн бұрын

    THANK U

  • @vivekchoudhary1907
    @vivekchoudhary19073 ай бұрын

    Comment ✔ I am in mbbs 1st year but in my free time instead of any so called fun hobby, i just goes to ninja nerd and click to a random video because it doesn't really matter , you can make an infant to understand the concept who just learn to speak language, # Keep up what you care for @ Zack💓❤‍🔥

  • @oshyobass8678
    @oshyobass8678Ай бұрын

    ❤❤❤❤ you are amazing 👏

  • @user-yw4si9kq8x
    @user-yw4si9kq8x3 ай бұрын

    Thank youu

  • @JansenMoloto
    @JansenMoloto2 ай бұрын

    Awesome

  • @queteimporta7049
    @queteimporta70493 ай бұрын

    The best in the world❤

  • @nhiphan7778
    @nhiphan77783 ай бұрын

    Could you please make videos about more detail on each test?😊

  • @maherninja1657
    @maherninja16572 ай бұрын

    God bless you

  • @FeHopeCyndiW
    @FeHopeCyndiW2 ай бұрын

    Thanks for the info and great videos! I have had asthma my whole life and feel like my lungs are working better than ever. I'm trying to understand my numbers from a recent PFT (done for another reason). My recent FEV1/FVC on a test was 64%. I feel like my lungs are super reactive and am 100% sure I have been dealing with asthma for the past 40 years, as diagnosed. I am allergen, exercise, and cold-induced and will wheeze loudly when triggered. I reacted so strongly to the methacholine challenge in the past that they shut down the test after the 1st lowest dose. I have been hospitalized in exacerbations where I needed IV steroids to get my lungs to work again. (I am a triathlete, so I exercise quite a bit, which I think has helped my lungs over the years.) But, for whatever reason, my change after a breathing treatment was only 8%. So, not asthma? If I felt like my lungs were working well before the administration of the albuterol. If my asthma was acting up, I would have expected a bigger change after the breathing treatment. But, not when I feel like I am breathing well. (Apparently, 64% is feeling well for me.) Why is the bar set at 12%? It seems to me that the change would depend on how constricted the airways were beforehand.

  • @cupkkate96
    @cupkkate962 ай бұрын

    thanks :)

  • @strivingsalafiyah_9899
    @strivingsalafiyah_98992 ай бұрын

    Favt teacher

  • @oxlopez
    @oxlopez4 күн бұрын

    🙌🙌🙌 you rock!

  • @James-tf2lc
    @James-tf2lc2 ай бұрын

    Good video, the only suggestion I'd give is that current ATS changed their post bronchodilation significant response value to 10% or greater.

  • @armin7855
    @armin7855Ай бұрын

    New things I learn't (for my own future reference) : * the volume loops in spirometry start from 0 which is to the right, hence in restrictive diseases, graph shifts to the right, and loop is smaller from reduced TLC. COPD, graph shifts to left and has kink. Also COPD has increased TLC from the hyperinflation. * If patient comes in with a resp. illness, do spirometry and peak flow meter tests. Those tell you if its obstructive or restrictive diseases (correlate with clinical history and exam). -> If COPD, then extra step here is to give them SABA to see if their FEV1 improves by 12%. If yes then thats asthma, if not then thats COPD -> Next common step in both obstructive and restrictive, is to give them CO and then see how much they exhale. Tells u how much CO is passing into alveoli. Thats the DLCO. If DLCO is low, thats narrows down the diagnosis. If suspicion was obstructive, then low DLCO indicates emphysema over chronic bronchitis. If suspicion was restrictive, then low DLCO indicates that its ILD - interstitial lung disease instead of an extra-pulmnoary cause eg. pectus excavatum etc. * One thing that was not discussed here was the AA gradient. Thats a good indicator to tell what the cause of hypoxaemia is (O2 sat less than 94%). AA gradient = dif. if O2 partial pressure b.w. alveolus and arterial blood. In a perfect world, all the O2 from alveolus would go to artery so AA gradient would be 0. But normal AA gradient is positive, and somewhere bw 5 and 15 (increases as you age, I guess because less O2 able to enter artery). Exact ideal AA = 2.5 + 0.21xage. If person is hypoxaemic, then AA gradient is higher, means some sort of V/Q mismatch exist obviously. Eg. asthma, COPD, bronchiectasis, cystic fibrosis, interstitial lung diseases (ILDs), and pulmonary hypertension etc. If hypoxaemia is present but AA gradient is normal, means diffusion seems to be fine, and cause of low O2 in blood is that less O2 is reaching the alveoli = hypoventilation mainly. Or could be that ur at mt. everest and the O2 in air is too low.

  • @rounaqhossain2211
    @rounaqhossain2211Ай бұрын

    these are too good to be available at free of cost.

  • @MUNEEBO
    @MUNEEBOАй бұрын

    Correction * RV + ERV = Functional residual capacity (FRC). This will increase in obstructive lung diseases and decrease in restrictive ones. TLC will remain the same however.

  • @tanveerabdullah3297
    @tanveerabdullah32972 ай бұрын

    My broo❤❤❤

  • @RashaAlBattat
    @RashaAlBattat2 ай бұрын

    the criteria you used for interpretration is old and not recommended anymore ,now the ATS and URS recommend to used LLN and Zscore and not used fixed precentage

  • @maherninja1657
    @maherninja16572 ай бұрын

    Cooool baby

  • @DhaniSaud.
    @DhaniSaud.Ай бұрын

  • @LauraNeumann-my3kb
    @LauraNeumann-my3kb22 күн бұрын

    I just feel like all of us listening to this ar

  • @user-ex6in9ej2i
    @user-ex6in9ej2i3 ай бұрын

  • @danaassaf
    @danaassaf9 күн бұрын

    ❤❤❤❤❤❤❤

  • @aloshtesulieman4164
    @aloshtesulieman41642 ай бұрын

    🥰🥰🥰

  • @javierasa3438
    @javierasa34382 ай бұрын

    🤩🤩🤩🤩🤩🤩🤩🤩🤩🤩🤩🤩

  • @aloshtesulieman4164
    @aloshtesulieman41642 ай бұрын

    😄😍😍

  • @aloshtesulieman4164
    @aloshtesulieman41642 ай бұрын

    🤩😘😗

  • @merisasuljkanovic8677
    @merisasuljkanovic8677Ай бұрын

  • @EmanuelaElaEla7
    @EmanuelaElaEla72 ай бұрын