Proteomics

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Proteomics is the large-scale study of proteins, particularly their structures and functions.[1][2] Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term proteomics was first coined in 1997[3] to make an analogy with genomics, the study of the genome. The word proteome is a blend of protein and genome, and was coined by Marc Wilkins in 1994 while working on the concept as a PhD student.[4][5]
The proteome is the entire set of proteins,[4] produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain formed on the basis of the research and development of the Human Genome Project;[citation needed] it is also emerging scientific research and exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.
While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry.

Пікірлер: 69

  • @aishwaryalaxmi144
    @aishwaryalaxmi1444 жыл бұрын

    You are doing a great job and your teaching way is just awesome. There is a great need of teacher's like you in colleges

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    Thank you so much for appreciating my efforts

  • @NareshKumar-ye3pr

    @NareshKumar-ye3pr

    6 ай бұрын

    Great 👍. Good video. But wanna tò know can we use use this technology for forensic science in place of DNA

  • @firozsheikh3352
    @firozsheikh33528 жыл бұрын

    best video ever ....you are getting so many blessings from us😇 thanks a lot for taking so much efforts you are awesome🙋

  • @mozafarahmed6041
    @mozafarahmed60417 жыл бұрын

    I love you man, just ... yeah, keep up the excellence, you're a life saver !

  • @shomusbiologyofficial

    @shomusbiologyofficial

    7 жыл бұрын

    +nefer pitou thank you very much.

  • @manishavibhute8466
    @manishavibhute84666 жыл бұрын

    your teaching explanation method is really very nice sir..

  • @salvadorhirth1641
    @salvadorhirth16414 жыл бұрын

    I would like to know if there is any controlled frameshift mutation that makes possible for one gene to have two layers of information, so that two complete functional proteins can be encoded by the gene and by the resulting frameshift mutation, please let me know if you have one example. Thanks!

  • @JordanOshiro
    @JordanOshiro8 жыл бұрын

    Thanks, that was helpful! Good explanation!

  • @nelsonandresrincontovar5862
    @nelsonandresrincontovar58629 жыл бұрын

    Thank You, very helpfull and enjoyable

  • @salvadorhirth1641
    @salvadorhirth16414 жыл бұрын

    Hi, thanks for sharing knowledge; please let me know if you know about the possibility to use fusion peptides with liposomes to deliver restriction enzymes into cells. I realized that a palindromic sequence like AAGCUU, has a limited possibility of mutations, therefore, about 27 different restriction enzymes should be able to cleave any given six bases palindromic sequence of viruses; think about the importance of a new approach to fight viral infections, borrowing restriction enzymes from bacteria. I hope that fusion peptides can make restriction enzymes penetrate the cytoplasm of cells, in order to cut viral RNA. This approach should not be safe to fight DNA viruses, because if the restriction enzyme able to cleave palindromic sequence get into the nucleus, it would damage non methylated cell DNA.

  • @logapriyars1946
    @logapriyars19465 жыл бұрын

    Can you mention the references from which you got these infos

  • @kritikabandge612
    @kritikabandge6126 жыл бұрын

    I think the pyramid diagram should be inverted as per the number of bases less then amino acids and then metabolites in max. no. and diversity also increase .

  • @oiawra
    @oiawra2 жыл бұрын

    thank you so much! this help me understand what proteomics is. thank you

  • @shomusbiologyofficial

    @shomusbiologyofficial

    2 жыл бұрын

    You're welcome

  • @WorldCollections
    @WorldCollections10 жыл бұрын

    Thank you! Although, what non of these proteomic videos clarify really well is how many simultaneous proteins can be analyzed by MS. I suppose that you can only pick one or two from the 2D gel separation, but not really throw at the MS a complete mix of proteins to get relative abundances?

  • @palvoliuto6059
    @palvoliuto60593 жыл бұрын

    Thank you very much Mr. Shomu. I've subscribed

  • @shomusbiologyofficial

    @shomusbiologyofficial

    3 жыл бұрын

    You're welcome

  • @user-hp4pk2pd9i
    @user-hp4pk2pd9i Жыл бұрын

    thank you for sharing ur knowledge wit us. can u send the reference books on this topic.

  • @sudalainitinmuthu238
    @sudalainitinmuthu2386 жыл бұрын

    Can you explain the scope for molecular medicinez??

  • @harishs2181
    @harishs21814 жыл бұрын

    I'm msc Chemistry I want learn bioanalytical which books I read?

  • @biology109
    @biology1094 жыл бұрын

    Sir what is the expected average of getting a parasite proteomics done.....any hints plzzzzz

  • @mehakmunjal2300
    @mehakmunjal23004 жыл бұрын

    Very helpful, Thanks a ton.

  • @Artscraft13
    @Artscraft1310 ай бұрын

    Thnk u ❤❤ nice explanation 😊😊everything is clear now about protiomics......

  • @shomusbiologyofficial

    @shomusbiologyofficial

    10 ай бұрын

    You're welcome

  • @mozafarahmed6041
    @mozafarahmed60417 жыл бұрын

    again, love you !

  • @melvingeorge2008
    @melvingeorge20084 жыл бұрын

    Thank you Shomu Sir!

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    You're welcome

  • @kaviyamehandiarts1987
    @kaviyamehandiarts19873 жыл бұрын

    Sir! please make a video on metabolic labelling.

  • @sarmilapanigrahi7617
    @sarmilapanigrahi76172 жыл бұрын

    Hello sir can u do a videos on bioinformatics and pharmacogenetics..I need to understand but it's little bit different to find...

  • @pragyasharma7986
    @pragyasharma79867 жыл бұрын

    thanks shomu

  • @basavarajkc3717
    @basavarajkc37174 жыл бұрын

    I am always gratitude to you sir

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    Thank you

  • @taniabatool4451
    @taniabatool44514 жыл бұрын

    You have always helped me

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    You're welcome

  • @hamsalekha38
    @hamsalekha384 жыл бұрын

    sir.can i have the references for this session.

  • @GoldiJ
    @GoldiJ10 жыл бұрын

    this is good and awesome....... thank you very much ........

  • @harinikrishnan8999

    @harinikrishnan8999

    10 жыл бұрын

    ingeyuma????????????????????????? thangamani mudiyala!!!!!!!!!!!

  • @nnminhanh
    @nnminhanh8 жыл бұрын

    Thank you

  • @nishimishra6361
    @nishimishra63613 жыл бұрын

    Sir if u have Ppt on this topic .. application of microbial proteomes please share with me

  • @lohoqalam2899
    @lohoqalam28993 жыл бұрын

    Sir kindly give lecture on SILAC technique

  • @Kyrani99
    @Kyrani995 жыл бұрын

    Great video and uptodate information. Good on you Shomu.

  • @shomusbiologyofficial

    @shomusbiologyofficial

    5 жыл бұрын

    You're welcome

  • @madwomanization
    @madwomanization10 жыл бұрын

    Hi do you have any videos on Transcriptomics

  • @shomusbiologyofficial

    @shomusbiologyofficial

    10 жыл бұрын

    Not now but I will be doing it soon.

  • @parikshitsalam9331

    @parikshitsalam9331

    7 жыл бұрын

    do u have video related to PROTEIN PROFILING TECHNOLOGY

  • @JShiwani
    @JShiwani2 жыл бұрын

    thankyou sir the lecture is really helpful .

  • @shomusbiologyofficial

    @shomusbiologyofficial

    2 жыл бұрын

    You're welcome

  • @bsc2microbio276
    @bsc2microbio2768 жыл бұрын

    thank youuso much....

  • @josephfolajimi9646
    @josephfolajimi96464 жыл бұрын

    wish there were subtitles

  • @ankushkalish1809
    @ankushkalish18096 жыл бұрын

    Proteomics changes...

  • @SumanMinj007
    @SumanMinj0074 жыл бұрын

    Sir... Your way of teaching is very well, But many Hindi medium students do not understand.. So please teach hindi english mix... 🙏🙏🙏🙏🙏🙏

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    I have 47% viewers from outside of India.

  • @swetasagarikaamanta6218
    @swetasagarikaamanta62184 жыл бұрын

    🙏🙏🙏🙏

  • @GHOOMANTUBETE
    @GHOOMANTUBETE2 жыл бұрын

    you are the best

  • @shomusbiologyofficial

    @shomusbiologyofficial

    2 жыл бұрын

    Thank you

  • @stephenprice3357
    @stephenprice33576 жыл бұрын

    I wish this video had subtitles bc this guy sounds like apooh from the Simpsons

  • @shreyaj1227
    @shreyaj12274 жыл бұрын

    Soon 800 K followers

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    Thank you

  • @pateldevang7486
    @pateldevang74864 жыл бұрын

    sabke exam najdik aa rahain so somu sir ke sub badh rahain😜😜

  • @shomusbiologyofficial

    @shomusbiologyofficial

    4 жыл бұрын

    Thank you

  • @akshayasasi7091
    @akshayasasi70913 жыл бұрын

    6.27

  • @rashamoustafa427
    @rashamoustafa4278 ай бұрын

    Great🎉🎉🎉

  • @shomusbiologyofficial

    @shomusbiologyofficial

    8 ай бұрын

    Thank you

  • @Ikigaizoologist
    @Ikigaizoologist4 ай бұрын

    Not upto the mark and as expected 😢