Platelets & Blood Clotting | Biology | FuseSchool

Do you remember tripping over as a kid and cutting your knee? And then like magic the bleeding suddenly stops? Have you ever wondered why this happens?
Our body is very clever and produces substances to seal off the open wound.
In this video we are going to look at how and why blood clots.
Clotting prevents us from bleeding to death, and also protects us from nasty disease-causing organisms, called pathogens, entering our body.
When we injure ourselves, we can damage the blood vessels just below our skin. This can cause blood to either leak into our tissue and form a bruise, or, if the skin is broken to openly bleed.
To prevent these horrible things happening, blood clotting occurs.
So let’s have a look at how this happens.
Starting with platelets. These are tiny cell fragments that float around in our blood.
When a blood vessel is damaged, collagen is exposed. This collagen exposure attracts platelets to the injured area. The platelets then stick together to form a plug.
They’ve quickly built a little barrier that stops us from losing too much blood. However, this platelet plug isn’t that strong. So it needs to be made stronger.
A protein called fibrin does exactly that.
In our blood there are soluble fibrinogen proteins. At a wound, these soluble fibrinogen proteins are exposed to outside chemicals that aren’t normally found in blood vessels. Like with the collagen and platelets, this exposure causes the fibrinogen proteins to turn into sticky fibrin fibres.
The fibrin fibres form a mesh, holding all the platelets together and making a much stronger clot.
More platelets, red blood cells and other components in our blood, all get stuck in the mesh making it even stronger. This clot stops more blood escaping the body. And also prevents nasty pathogens entering our body from the outside.
The clot develops into a scab, which protects the wound as it heals and new layers of skin form underneath. So really, all a scab is is just platelets trapped in the fibrin mesh!
When the new skin is fully formed, the scab will fall off, revealing the lovely brand new skin underneath.
Remember that I said the exposure to collagen causes the platelets to stick together? And the exposure to outside chemicals causes the fibrinogen to turn into sticky fibrin?
Both the platelets and the fibrin only become sticky AFTER the exposure. This means that in a normal, healthy blood vessel they won’t randomly cause clots.
So from this video, you should understand the magic of blood clotting. Platelets are first to the scene closely followed by fibrin fibres. Our blood clots so that we don’t lose a lot of blood and don’t let lots of nasty pathogens into our body if we cut ourselves.
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Пікірлер: 196

  • @catelynrossetto4279
    @catelynrossetto42793 жыл бұрын

    Thanks. Just showed this to my 6 year old daughter after getting a cut in her hand. Now she's looking at the cut and saying, "You're doing a great job platelets!" ☺️

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Aww 🥰 So glad to hear that!

  • @peachblossom5209
    @peachblossom52094 жыл бұрын

    FINALLY a video from this channel that has actual audible pronunciation OMG

  • @ianhuang8088
    @ianhuang80884 жыл бұрын

    Finally a video about blood clotting I can finally understand.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad it was helpful!

  • @stephanylara363
    @stephanylara3633 жыл бұрын

    A simple explanation, just what I needed.

  • @socialtech1692
    @socialtech16923 жыл бұрын

    You elaborate it in a very simple way!! Thank you

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thank you too! Glad you liked it!

  • @safajannat4194
    @safajannat41945 жыл бұрын

    Can u make a detailed video on blood clotting where the function of thrombokinase, prothrombin , fribrinogen and fibrin are given properly

  • @janenduati7581

    @janenduati7581

    3 жыл бұрын

    Exactly

  • @akshayar4444

    @akshayar4444

    2 жыл бұрын

    Yes that's what i'm searchin for

  • @akshayp7489
    @akshayp74895 жыл бұрын

    Were is thrombin and prothrombin😶

  • @lehaswinipalla3365
    @lehaswinipalla33655 жыл бұрын

    This is exactly what I was looking for. Thank you so much !!!!

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thank you!

  • @ahm3212
    @ahm32123 жыл бұрын

    That's what I was exactly looking for! Many thanks.

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Excellent! Glad we could help!

  • @trighoo
    @trighoo4 жыл бұрын

    I wanna ask. How betadine help platelets? Or any medicine that we take when we are wounded. Thank you in advance

  • @meganlim7285
    @meganlim72854 жыл бұрын

    When there’s an open wound, platelets will release chemicals that cause a soluble fibrinogen protein to convert into a insoluble fibrin and insoluble mesh. This will allow the blood cells to trap and therefore forming a clot. When the clot dries, it will form a scab that prevents bacteria from entering the wound .

  • @ahmedyasir8454

    @ahmedyasir8454

    4 жыл бұрын

    1234

  • @DanDanCrafts
    @DanDanCrafts4 жыл бұрын

    Wow now I understand this in only 3 MINUTES!?!?!? This is insane and may be really helpful

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad you think so!

  • @irenevillatoro2975
    @irenevillatoro29753 жыл бұрын

    You explain simply and easy thank you so much ☺️

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thank you! So nice of you 😊

  • @jordand.7579
    @jordand.75793 жыл бұрын

    Thank you, explained in a very simple way and straight to the point.

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thank you too! Glad you liked it!

  • @kathleenratcliffe3175
    @kathleenratcliffe31754 жыл бұрын

    Excellent video!!!!

  • @avinashjohnson3374
    @avinashjohnson33743 жыл бұрын

    You have help me revise for my test thank you so much 😊

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    So glad! Always happy to help!

  • @devandgouri
    @devandgouri2 жыл бұрын

    Good information.. Easy to understand

  • @shinigglory3689
    @shinigglory36892 жыл бұрын

    Thanks for this informational ❤️❤️

  • @Queen-ij4ix
    @Queen-ij4ix2 жыл бұрын

    What is the difference between hemostasis, blood clotting and coagulation? All 3 processes are quite similar which makes it confusing to understand

  • @fuhkuhmi5175
    @fuhkuhmi51752 жыл бұрын

    What a fantastic mechanism our body has it surprises me everyday God has created us so finely 🙏

  • @yadavshipra
    @yadavshipra4 жыл бұрын

    Thanx for explaining this way

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad you liked it!

  • @peterleclair6987
    @peterleclair69872 жыл бұрын

    Is the same thing done after mass surgery for triple by pass.

  • @diegodelossantos8249
    @diegodelossantos82495 жыл бұрын

    this really helps thanks

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad it does!

  • @nehavathana3428
    @nehavathana34283 жыл бұрын

    thank you so much for sharing thiss...its very helpfull..

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    You're welcome! Glad it was helpful!

  • @palak6981
    @palak69812 жыл бұрын

    Are there collagen fibres in blood capillaries too?

  • @Hopedespitethepain
    @Hopedespitethepain3 жыл бұрын

    Excellent explanation 👌 thank you

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Most welcome! Glad you liked it!

  • @martinjimenez7392
    @martinjimenez73925 жыл бұрын

    So simple and detailed I love it.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad you think so!

  • @ahmedyasir8454
    @ahmedyasir84544 жыл бұрын

    Thanks for the fascinating video

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks for watching :)

  • @mey4034
    @mey40343 жыл бұрын

    Thank you xora for sharing 😍😍😍

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Our pleasure 😊

  • @BrightMsowoya-jk7ym
    @BrightMsowoya-jk7ymАй бұрын

    Thanks. Your video it help he to know some of blood

  • @naveensundar4765
    @naveensundar47654 жыл бұрын

    Thank you very much.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    No problem!

  • @pharmacyclass443
    @pharmacyclass4435 жыл бұрын

    wonderful thanks

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thank you!

  • @MamtaSingh-jc4rh
    @MamtaSingh-jc4rh3 жыл бұрын

    Really you are a very good teacher

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thank you! 😃

  • @sanjuktapatra4775
    @sanjuktapatra47755 жыл бұрын

    Wow... Nice explaning. 😀👍👌

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks!

  • @MamtaSingh-jc4rh
    @MamtaSingh-jc4rh3 жыл бұрын

    Thank you so much sir

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Most welcome!

  • @sumaiyachowdhury8967
    @sumaiyachowdhury89673 жыл бұрын

    Thanks it was helpful. Give more educational videos

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Glad it was helpful 😉

  • @meghakiran8426
    @meghakiran84264 жыл бұрын

    Thank you

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Any time!

  • @OneOfYourFrenchGirIs
    @OneOfYourFrenchGirIs3 жыл бұрын

    Thank you:) 💚💚🕊

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    You are welcome 💜

  • @m.a.p.g.
    @m.a.p.g.2 жыл бұрын

    Thank you from a #TTP (Thrombotic thrombocytopenic purpura) patient.

  • @angelrivcal6334
    @angelrivcal63344 жыл бұрын

    AMAZING VIDEO

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    THANKS!

  • @courtneysimons3344
    @courtneysimons33444 жыл бұрын

    Well done!

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks!

  • @courtneyklaft9940
    @courtneyklaft99403 жыл бұрын

    so having a high platelet count is a good thing?

  • @varshithveeravarapu9118
    @varshithveeravarapu91185 жыл бұрын

    How does fibrin get activated

  • @manis7994
    @manis79942 жыл бұрын

    AmazING videos

  • @fuseschool

    @fuseschool

    2 жыл бұрын

    Thank you!

  • @pearlagbodza5379
    @pearlagbodza53794 жыл бұрын

    Nice video i love it

  • @veronicavargas8593
    @veronicavargas85932 жыл бұрын

    If you blood platelets are low what medicine can help you reach your levels of platelets

  • @LearnIndiaLearn
    @LearnIndiaLearn5 жыл бұрын

    2nd comment thanx for the video👌 Please make a video on Blood plasma and serum.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Noted! Thanks!

  • @aramqaladzay3818
    @aramqaladzay38184 жыл бұрын

    Si helpful thank youu

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad it was helpful!

  • @youtuber5412
    @youtuber54123 жыл бұрын

    Can i get a heart for my fav teaching channel ❤❤❤❤

  • @wago6144
    @wago61443 жыл бұрын

    Ok so how can you explain this in relation to the Covid-19 vaccines?

  • @LuigiTheMetal64
    @LuigiTheMetal644 жыл бұрын

    Compare that to Cells at Work. In the anime, the platelets make a net to stick the red blood cells on it, which is correct. The platelets themselves just stay inside the body and let the red blood cells die. They did not fuse with the reds.

  • @abby2857
    @abby28575 жыл бұрын

    Really helpful👏👏

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad it was!

  • @Swordman2566
    @Swordman25662 жыл бұрын

    wow it is cool very cool

  • @monirahalyaseen542
    @monirahalyaseen5423 жыл бұрын

    Thhhankss!!

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    No worries!

  • @zwiirekgodking1641
    @zwiirekgodking16414 жыл бұрын

    Tiny cells in the blood called platelets stick together around the wound to patch the leak. Blood proteins and platelets come together and form what is known as a fibrin clot. The clot acts like a mesh to stop the bleeding. ... Each factor activates the next until they form a clot.

  • @yunaelia
    @yunaelia3 жыл бұрын

    Hey! Great video but I have a question. What is collagen? Is it a layer of skin? Or it it air around the body? 😅 Is it just floating on our skin or is it underneath a layer??

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    This might help: www.medicalnewstoday.com/articles/262881

  • @yunaelia

    @yunaelia

    3 жыл бұрын

    @@fuseschool Thank you very much!!!

  • @2bgaming425
    @2bgaming4253 жыл бұрын

    Very nice thankyou

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Most welcome 😊

  • @sajalpatil8939
    @sajalpatil89393 жыл бұрын

    It is very good

  • @RandomPerson-rw1vs
    @RandomPerson-rw1vs5 жыл бұрын

    Anone Anone

  • @54Aakash
    @54Aakash5 жыл бұрын

    keep going.good.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Will do!

  • @bgramachandrautube
    @bgramachandrautube3 жыл бұрын

    thank you I am using your videos for my teaching during covid 19 situation - which is non commercial purpose

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Wonderful! Glad they are being useful 🙂

  • @oinker1695
    @oinker16953 жыл бұрын

    After watching CAW all i can think of when i hear platelet is just cute kids.

  • @safajannat4194
    @safajannat41945 жыл бұрын

    Every biology video that I've watched infuse school gives me an incomplete information about different stuffs. The biology related videos are not as much as fruitful as chemistry and maths . Hopefully in future we'll get good biology related video

  • @melissagordillo7212
    @melissagordillo72122 жыл бұрын

    Good ass video keep it up

  • @adrianharo6586
    @adrianharo65865 жыл бұрын

    Thank you for the amazing animation

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks for watching!

  • @kimjasmine7767
    @kimjasmine77673 жыл бұрын

    The funny thing is they advistise how to slim down to a skinny person..... 😊Good explanation on platelets and blood clot.

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thanks! Glad you liked it!

  • @techerz2.0
    @techerz2.03 жыл бұрын

    Who else had their teacher show this at class.?

  • @user-ul2gl1ly8o
    @user-ul2gl1ly8o3 жыл бұрын

    Good video and easy to understand From IQ

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thank you! Glad you like it!

  • @studypug7244
    @studypug72443 жыл бұрын

    good video

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thanks!

  • @happinesslovee
    @happinesslovee3 жыл бұрын

    I have had the disease itp low platelets for years. it affects my whole life. now also in hospital on IV. what a rare rotten disease it is. And the drugs also have their serious side effects. I hope it's just curable

  • @doriskuen2874

    @doriskuen2874

    2 жыл бұрын

    I’m having the same problem. Had Rituxan infusions, didn’t get platelets up. Now doc wants to start Promacta. I’m frustrated they can’t find the cause. Don’t want another drug. What is out there to cure it.

  • @joaocarrilferreira4590
    @joaocarrilferreira45903 жыл бұрын

    Nice!

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thanks!

  • @joaocarrilferreira4590

    @joaocarrilferreira4590

    3 жыл бұрын

    @@fuseschool

  • @dianarios3027
    @dianarios30275 жыл бұрын

    You are amazing!! Thank you.

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Aww thanks!

  • @danfordmukwevho7104
    @danfordmukwevho71043 жыл бұрын

    Due to the effect of Haemophilia causing blood not to clot what could be affected

  • @youtuber5412
    @youtuber54123 жыл бұрын

    I am trying to understand it but i couldn't after seeing this video it become clear

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Wonderful 😃

  • @youtuber5412

    @youtuber5412

    3 жыл бұрын

    Sir I need your blessing for my exam

  • @seniquewilliams1921
    @seniquewilliams19213 жыл бұрын

    what are the blood vessels

  • @Farhan-ns2kg
    @Farhan-ns2kg2 жыл бұрын

    Subahanallah

  • @shaezagriffin9313
    @shaezagriffin93135 жыл бұрын

    Thank you so much for this video

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks for watching!

  • @karens997
    @karens9975 жыл бұрын

    helped me visualise easier. thank you

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Glad it helped!

  • @donmichaelastor7903
    @donmichaelastor79033 жыл бұрын

    Thank youu

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    No problem!

  • @bhagi1236
    @bhagi12364 жыл бұрын

    Good 👍

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Very good!

  • @oreacollins5703
    @oreacollins57032 жыл бұрын

    If your body Is making too many palates what can you eat

  • @shahnawazshanu3301
    @shahnawazshanu33013 жыл бұрын

    What is the role of vitamin K in case of blood clotting

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Vitamin K helps convert certain blood clotting factors that are involved in formation of the clot. Check this article out: www.newscientist.com/article/mg13217963-100-science-how-vitamin-k-makes-blood-clot/

  • @floyelcaseres1977
    @floyelcaseres19773 жыл бұрын

    How to cure im easy bleeding

  • @subodhjadhav4367
    @subodhjadhav43674 жыл бұрын

    nice vedio

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Thanks!

  • @mimis_jail
    @mimis_jail4 жыл бұрын

    you know what I recommend cells at work to you :3 *watch the anime or the germs will get you*

  • @mbart5113
    @mbart51133 жыл бұрын

    Does anyone feel afraid of the red blood cells and the white blood cells and the platelets?

  • @user-ul2gl1ly8o
    @user-ul2gl1ly8o3 жыл бұрын

    You: you remove the scab Platelet: ah shit here we go again

  • @rajjaiswal62
    @rajjaiswal624 жыл бұрын

    Please allow to see private video it is very useful

  • @phirigreyson1477
    @phirigreyson14775 жыл бұрын

    Zambian

  • @miamor9224
    @miamor92243 жыл бұрын

    Are platelets same as lipids?

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Hi there! Platelets are not the same as lipids. They are composed of different lipids, e.g. phospholipids, sterols, sphingolipids, free fatty acyls and glycerolipids.

  • @rajjaiswal62
    @rajjaiswal624 жыл бұрын

    Why we can not see private videos

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    We might need to fix a few things in those videos before we make them public again. Bear with us!

  • @rajjaiswal62

    @rajjaiswal62

    4 жыл бұрын

    Ok I understand but when we see private videos

  • @maryamalmafraji9189
    @maryamalmafraji91893 жыл бұрын

    this man did not just say magically twice in a scientific video

  • @maryamalmafraji9189

    @maryamalmafraji9189

    3 жыл бұрын

    the video was quite helpful though

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Glad ti was helpful!

  • @abhijeetdutta0798
    @abhijeetdutta07982 жыл бұрын

    Fibrin clot ???

  • @unboxing.delights
    @unboxing.delights3 жыл бұрын

    u good

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Thanks 😉

  • @omerhijazi498
    @omerhijazi4983 жыл бұрын

    0:49 whats eed

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    You probably meant "bleed". The narrator says: "When we injure ourselves, we can damage the blood vessels just below our skin. This can cause blood to either leak into our tissue and form a bruise, or if the skin is broken to openly bleed."

  • @omerhijazi498

    @omerhijazi498

    3 жыл бұрын

    @@fuseschool I meant that theres some error in the video, a random noise (eed) comes

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Oh, ok. Thanks for pointing it out.

  • @omerhijazi498

    @omerhijazi498

    3 жыл бұрын

    @@fuseschool Welcome :)

  • @DOERXSTREET
    @DOERXSTREET3 жыл бұрын

    My teacher sent me

  • @hiromanjiro8105
    @hiromanjiro81053 жыл бұрын

    Thanks I had an exam

  • @fuseschool

    @fuseschool

    3 жыл бұрын

    Hope it went well!

  • @qadarinimo258
    @qadarinimo2585 жыл бұрын

    Help!!!!! Calculate the number of grams of substance needed to make each of the following solutions 1. 100cm3 of KOH concentration 0.5mol/dm3 NEED HELP IMMEDIATELY!!!!

  • @struggling_college_student

    @struggling_college_student

    4 жыл бұрын

    oop-

  • @pr3ppr396

    @pr3ppr396

    3 жыл бұрын

    @@struggling_college_student bit late

  • @-tilma-454
    @-tilma-4543 жыл бұрын

    who needs to read about blood cells and stuff when u can watch "cells at work"--

  • @LuigiTheMetal64

    @LuigiTheMetal64

    3 жыл бұрын

    That show is not accurate. In the show, the platelets never stick with the red blood cells as the platelets just stay in the body. The red blood cells are seen carrying food baskets to represent nutrients, when in reality, red blood cells only carry CO2 and oxygen whereas the plasma is what carries the vitamins and minerals.

  • @keystick_
    @keystick_5 жыл бұрын

    luv it

  • @fuseschool

    @fuseschool

    4 жыл бұрын

    Amazing!