Pediatric Fever: Diagnostic Testing by Jess Monas, MD
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Key Points and Recommendations
1. Tactile fevers should be regarded as real fevers, even if afebrile in the ED.
2. CBC as a screening test has a sensitivity below 50% for SBI.
3. The sensitivity of CRP ranges from 34%-75% depending on cut-off levels.
4. The sensitivity of PCT ranges from 30%-82% depending on severity of illness and cut-off.
5. Messenger RNA biosignatures are both highly sensitive and specific.
6. LP rarely identifies meningitis in children 29-60 days of age who meet low-risk criteria.
7. Long term sequelae of missed UTI are rare.
8. UTI can be screened for with a urine dipstick positive for either nitrites or leukocyte esterase.
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