Pathogenesis of Preeclampsia | Pregnancy induced Hypertension | Nursing Lecture
Preeclampsia is a pregnancy-specific disorder, caused by the gravid state of the uterus. Here in this video, the pathogenesis of this disorder is explained, from where this disorder begins.
The Etiopathogenesis are-
1. Abnormal Trophoblast Invasion -
In Preeclampsia the Extravillous trophoblast fails to invade the spiral arteriole in the 2nd trimester thereby the diameter of the vessels remains narrow and causes high resistance and low blood flow thereby causing hypoxia, ischemia.
2. Genetic Factors
Many of the genes are responsible for Hypertension.
3. Immunological Maladaptive Tolerance
Trophoblast express non-classical MHC (major histocompatibility complex) which is recognized by the dNK cells and stops the cytotoxic response by the T cells and these natural killer cells allows the trophoblastic invasion.
As the tissues become hypoxic there is less expression of the MHC molecule thereby the T cell-mediated response is increasing and by the various inflammatory mediators, antiangiogenic factors, and the imbalance between the vasodilators and vasoconstrictor causes endothelial dysfunction or the endothelial cell activation.
So as the vessel starts to damage there is vasospasm which causes hypertension, and leakage of fluid into the interstitial space causes Oedema and proteinuria.
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Пікірлер: 43
Excellent representation of the concept maam. Doubts got cleared
@NursingLecture
Жыл бұрын
Thanks a lot
It's very useful. Thank you so much Mam🥰
Bestest tutor ❤️...
Thank u mam very clear explation
Thank u mam your teaching make easy understand mam plz upload shoulder dystocia
Mam aap bhaut aacha padhati hai....
@NursingLecture
3 жыл бұрын
Thank you 😊
Thank you ❤️❤️
Too much effective...thank you
Mam plz discuss about infertility and endometriosis
Wow.. Nice cls mam.. 💓
@NursingLecture
2 жыл бұрын
Thank you
thank you ma'am 🙏
@NursingLecture
5 ай бұрын
Most welcome 😊
Thank you so much mam❤
@NursingLecture
11 ай бұрын
Most welcome 😊
Thankuu mam ☺
Mamm Hemorage in early pregnancy is not clear plz mamm take class on this chapter ☺️
Mam u r great 💓💓💓
@NursingLecture
Жыл бұрын
Thanks a lot 😊🙏
@ruqiyarashidruqiyarashid656
Жыл бұрын
@@NursingLecture mam do you have lecture related to Torch infection
Tq mam
Love from Kerala
@NursingLecture
Жыл бұрын
👍🙏
Thnku mamm
Are these the same as theories of pre-eclampsia
Mam please tell about meaning of inflammatory mediators and oxidative stress
@NursingLecture
2 жыл бұрын
Inflammatory mediator causes vasodilation of vessels that are leaky and promote edema and facilitate immune cell infiltration. Oxidative stress is the disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses, thereby causing tissue damage.
@umamaheshwari4388
2 жыл бұрын
@@NursingLecture thank you mam
Tq mam🥰🥰🥰
Mami pls make more vedik in hemborage inearly pregnancy , pls mamm
Thnku mamm your teaching make easy to understand
Maam plz hemborage in early pregnancy chapter m class lo 🙏🙏🙏🙏
Mam , Is placenta produced inflammatory mediators and why?
Mam plz give me the link of clinical course of first and 2nd and 3rd stage labor
@NursingLecture
3 жыл бұрын
kzread.info/dash/bejne/fIJ3xMqGXZutn9Y.html kzread.info/dash/bejne/hHykrLSPpsa9cc4.html kzread.info/dash/bejne/ZqeXwdeMirKyqpM.html
@NursingLecture
3 жыл бұрын
Plz in my channel check out the playlist also or you can download my nursing lecture app so you can get the content systematically
@gargikhatua6761
3 жыл бұрын
OK mam thank you mam
👏🏾👏🏾👏🏾👏🏾👏🏾👏🏾👏🏾🇰🇪
Madam B.sc nursing me admission le na ha koi achha college ka name batye
Ma;am, how important is this topic from comp exam point of view?
@NursingLecture
3 жыл бұрын
Imp to clear the concepts