Neurodegenerative Disorder II - Parkinson's and Huntington's

armandoh.org/
Brief Introduction to the pathophysiology of Parkinson's and Huntington's
Song: Angus and Julia stone - Devil's tears
Facebook: / armandohasudungan

Пікірлер: 77

  • @jahblazek
    @jahblazek9 жыл бұрын

    Helpful Pneumonic on the symptoms of Parkinsons: TRAP (as in you are trapped in your own body) Tremors Rigidity Akinesia (low movement) Postural immobility

  • @alistairleaver3046
    @alistairleaver30468 жыл бұрын

    I love your videos Armando... One error I'd point out in this one is that dopamine loss does not cause tremous in PD, deranged acetylcholine circuits are responsible for this. Dopamine actually accentuates motor signalling by exciting the direct pathway (which is itself excitatory) and inhibiting the indirect pathway (which is inhibitory). Thus reduction in dopamine --> reduction in motor signalling --> bradykinaesia. Keep up the good work mate!

  • @DucatiLou81
    @DucatiLou8110 жыл бұрын

    Armando, you have come along way with your videos. I applaud your artistic prowess and teaching skills.Your videos help me so much since I am an auditory-visual learner. Thumbs up always!!!!

  • @drew9312
    @drew93128 жыл бұрын

    Love your illustrations. Thanks for putting so much work into this for us!

  • @studyroyal
    @studyroyal8 жыл бұрын

    I am always happy that your channel exist!!

  • @baabaq9126
    @baabaq91268 жыл бұрын

    extremely helpful and pretty understandable. im supposed to write a term paper on a named neurodegenerative disease so this really helped

  • @mistyaquilar5544
    @mistyaquilar55448 жыл бұрын

    THANK YOU! FOR MAKING A VIDEO THAT I CAN UNDERSTAND. AND SO CAN MY FAMILY AND FRIENDS.

  • @raysambaraka2469
    @raysambaraka24698 жыл бұрын

    Thanks mate. Awesome illustrations!!!

  • @sKennedy946
    @sKennedy94611 жыл бұрын

    This song was stuck in my head all weekend (which is a GOOD thing with a test coming up) so thank you!!! Very helpful. Please make more! :) :) - Nursing student.

  • @TheHummmeer
    @TheHummmeer10 жыл бұрын

    Great videos Armando!

  • @jonramsay5123
    @jonramsay51239 жыл бұрын

    brilliant! keep up the awesome work!

  • @cathrinezenlim4474
    @cathrinezenlim44743 жыл бұрын

    the lecture is precise and very clear

  • @cellybelly13
    @cellybelly1311 жыл бұрын

    very good explanation on the differences.

  • @angelataylor2883
    @angelataylor288311 жыл бұрын

    Beautiful drawings, very helpful- great video. Thanks

  • @hugh3196
    @hugh319610 жыл бұрын

    would be good to do a video on indirect and direct pathway

  • @ashleighblankenship3774
    @ashleighblankenship37744 жыл бұрын

    Great video! Super helpful info

  • @emailamyhess
    @emailamyhess11 жыл бұрын

    Really enjoying your videos, thanks!!

  • @shaymaalb
    @shaymaalb7 жыл бұрын

    very helpful. thank you so much

  • @shivleengill4976
    @shivleengill49768 жыл бұрын

    great for quick review thanks

  • @sarahchewsuemei
    @sarahchewsuemei10 жыл бұрын

    thank you Armando! that was a helpful overview!! : )

  • @user-cm8mo7gm9b
    @user-cm8mo7gm9b3 жыл бұрын

    Amazing and clear

  • @terminateTHEhate8
    @terminateTHEhate811 жыл бұрын

    THIS VIDEO WAS PERFECT. AMAZING DRAWINGS, SO ACCURATE! YOU RULE MAN, KEEP IT UP AND THANK YOU VERY MUCH :)

  • @dddeeksha8521
    @dddeeksha85219 жыл бұрын

    Will a person suffering from Parkinson's disease have difficulty in stopping the initiated movement?

  • @michellefolkert
    @michellefolkert12 жыл бұрын

    This was so helpful!! Thanks!

  • @BallyBoy95
    @BallyBoy957 жыл бұрын

    Did you just apologise for talking quick at the end? Honey, you talked perfectly fine. XD

  • @SherriAD
    @SherriAD10 жыл бұрын

    Very informative!

  • @erikkelly6893
    @erikkelly6893 Жыл бұрын

    Very helpful, thank you.

  • @carlyknight1281
    @carlyknight12816 жыл бұрын

    Such a helpful video

  • @dj912sent9
    @dj912sent95 жыл бұрын

    Can a person with Parkinson’s have involuntary movements but no tremors? Many people who have Huntington’s can be misdiagnosed as having Parkinson’s. What is the clear difference between the two in terms of movements? Or can they be very similar? Can a person have involuntary movements and no tremors and still have Parkinson’s? Or would that indicate a possibility of Huntington’s?

  • @PeassnCarrotss
    @PeassnCarrotss10 жыл бұрын

    Exam tomorrow, thank youuuuu :)

  • @watchinguwatchme
    @watchinguwatchme10 жыл бұрын

    so easy to follow it really helps when the text books fail

  • @dddeeksha8521

    @dddeeksha8521

    9 жыл бұрын

    Even the lectures fail

  • @lauracarrillo884
    @lauracarrillo88410 жыл бұрын

    great video !

  • @moments8562
    @moments85623 жыл бұрын

    thanks for this!!

  • @sarahalexander3255
    @sarahalexander3255 Жыл бұрын

    I love this video and the animations!! I am taking a patho class currently and often refer to other videos to further understand. I am left a little confused though because my patho professor said that there is actually an excess of dopamine levels and upon further research I have read that there are increased levels of dopamine, but in your video you said that dopamine levels remain normal?

  • @loriwilson3254
    @loriwilson32543 жыл бұрын

    Good stuff!

  • @mhmtL
    @mhmtL9 жыл бұрын

    for Huntington disease, some sources say a mutatian in Huntington Gene that produce huntington protein which have more glutamate compared with normal protein. However, in this video you mentioned about lacking of GABA. well to be honest I'm confused a little bit.

  • @harrykarna3604

    @harrykarna3604

    9 жыл бұрын

    +mehmet aLi GABA is inhibitory and Glutamate is excitatory. So reduced GABA or increased Glutamate will give you the same effect. Both are neurotransmitters in the basal ganglia which is responsible for movements. Hope that helps. You might want to take a look at some videos on Basal ganglia direct and indirect pathways.

  • @TransformChantel
    @TransformChantel8 жыл бұрын

    could you update this video please

  • @babeeshcv2484
    @babeeshcv24849 жыл бұрын

    thnk u...........

  • @tc5290
    @tc52907 жыл бұрын

    Really amazing video, it is very very helpful for my studies. May I ask, based on the video, is dopamine continually released, and is it continually released due to us thinking of most of the time? Is that why the shakes occur (rapid intentions to move), taking into account reduction in GABA.

  • @tc5290

    @tc5290

    7 жыл бұрын

    Thank you very very much by the way

  • @pinakiganguly8447
    @pinakiganguly84473 жыл бұрын

    Awesome

  • @kuku7023
    @kuku702311 жыл бұрын

    Well explain

  • @vrischikachabella1935
    @vrischikachabella19359 жыл бұрын

    do you have a picture of this? this is amazing :)

  • @AndrewCreary
    @AndrewCreary10 жыл бұрын

    thank you, saved my ass on a physiology exam question. my notes had it backwards.

  • @GarethNicholas8
    @GarethNicholas810 жыл бұрын

    pretty sure its striatum not stratium

  • @andreaziz5499
    @andreaziz54994 жыл бұрын

    how to fotify dopermine

  • @ShubhamKumar-rd3cw
    @ShubhamKumar-rd3cw3 жыл бұрын

    bro your videos are awesome but can you plz make this video once more this has low voice quality nd pictures are very small plz its a request your videos are very helpful In my med school

  • @rickosban897
    @rickosban897 Жыл бұрын

    I have Parkinson’s in my right hand will eventually it move towards my left

  • @choney26
    @choney268 жыл бұрын

    cool video, but it's called STRIATUM, not STRATIUM

  • @tomifiju
    @tomifiju4 жыл бұрын

    5:15 is the best part :D

  • @alvinbilley5862
    @alvinbilley5862 Жыл бұрын

    i wonder how many studnets were misled by inaccurate info in these videos

  • @phaseoneb2926
    @phaseoneb292611 жыл бұрын

    striatum**

  • @gunterliam7411
    @gunterliam74112 жыл бұрын

    All thanks to dr Stanley who cured me from my Huntington’s disease I am forever grateful

  • @dr.s.m.sureshbabu8699
    @dr.s.m.sureshbabu869911 жыл бұрын

    genius wre is the explanation about the direct nd indirect pathways involving {globus pallidus,substantia nigra,subthalamic nuclei,anterior and lateral thalamic path ways}? whatever is hapening in basal ganglia is just a game between then ...wats the point explaining the disorder without explaining the pathway??anyways...ur sketches r good ...

  • @lilacehakoun818
    @lilacehakoun81811 жыл бұрын

    U ROCK!!! :D :D :D

  • @janemike3490
    @janemike34902 жыл бұрын

    #drojeabacha