Eunice S. Wang, MD, Roswell Park Comprehensive Cancer Center, Buffalo, NY, provides an overview of key updates in leukemia presented at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting, including novel approaches using bispecific antibodies, as well as targeted approaches in acute myeloid leukemia (AML). This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.