A part of the final exam for an organic chemistry lab course was to follow a synthetic procedure to get a product. They did it in pairs. So a couple of students got to prepare acetylsalicylic acid (aspirin). At the end they were supposed to get crystals but instead they were left with some wierd yellow oil with no chance to crystallize. They were sure they had failed the test. Until one of them remembered he had a pack of aspirin pills in his backpack. Bingo! They quickly crushed them, extracted with chloroform, and recrystallized to get really nice crystals. So the prof came and examined the product. He asked them many questions about the procedure, reaction conditions etc. At the end he scratched his head and said: "You know, every year we get this wierd yellow oil, but you guys were the first to get crystals!"

@spiderman1579

2 жыл бұрын

How did every year all get yellow oil? The specific extraction for the test what different from what they quickly did last minute?

@eloquentia7207

2 жыл бұрын

@@spiderman1579 I guess that the procedure they gave students year after year was not very reliable and did not lead to the desired product, but the profs were too lazy to look for another one and didn't care. On the other hand, commercial aspirin does, of course, contain a lot of aspirin, so the students were able to recrystallize it.

@spiderman1579

2 жыл бұрын

@@eloquentia7207 right but they must have used a different method then the exam no?

@eloquentia7207

2 жыл бұрын

@@spiderman1579 one of them had aspirin pills in his bag by chance, so they had access to their final product in great amount and high purity. They discarded the yellow oil and continued working with the pills.

@Lambda_Ovine

2 жыл бұрын

Aspirin has aspirin. Can I have my PhD in chemistry now please?

As a wastewater treatment technician, Nile Red's Videos keeps my mind fresh and with ideas!

@Adrian-vd8rm

4 ай бұрын

U be extracting shit from shit water ?

@j0hnny_R3db34rd

3 ай бұрын

@@Adrian-vd8rm No he be extracting water from shit and making shit drinkable.

I think it would have actually been interesting to see the video of the failed lidocaine extraction, to see what can happen and the creative thinking that goes with trying to solve unexpected issues.

@peterdevaux4394

Жыл бұрын

.

@christopherbarnard9672

10 ай бұрын

​@@peterdevaux4394😂🎉I honestly don't wor😊

@j0hnny_R3db34rd

3 ай бұрын

But that never happens.

I've been looking for this since I first discovered psychedelics.

@FreakinKatGaming

6 жыл бұрын

You are smarter then you need to be little one. Why not go enjoy life and wait a little before you go down that road.

@Septiviumexe

6 жыл бұрын

I agree, good for a monthly fix, but dont get too attached. Your brain is too valuable

@krisraps

6 жыл бұрын

Sak Sezo, Domn`t listen to these people, do what you wnat to do and don`t listen nobody. JUST DO IT! Make extract codeine, morphine, methadone out of everything, do it, use it, but be cerafuklll, they are some hell of a drug

@krisraps

6 жыл бұрын

Agree

@Lrofmaulol

6 жыл бұрын

TheStonedGamer 420 'I'm 16... My PTSD' Right. Fucking millenials.

We all know why were here

@mlwiz950

6 жыл бұрын

This is the realest comment I've ever seen on KZread

@dimentbarg9793

6 жыл бұрын

I don't tbh

@Oroborospaces

6 жыл бұрын

@@dimentbarg9793 drugs

@chaseramos4865

5 жыл бұрын

Why?

@chaseramos4865

5 жыл бұрын

@@Oroborospaces what are pa drugs

Nice job on the video I find it quite helpful! Have a great one!

I love your videos so much! they make me motivated to do chemistry

I'm impressed by your knowledge. So far you've taught me how to make acetone ,ethanol more. Thanks👍

@gagemal5

5 ай бұрын

To be completely fair ethanol is like one of the simplest compounds to make it’s dicarbon primary alcohol, wait till you find out about 6 member ring secondary alcohols with two delocalized electrons clouds spinning in circles above and below the alcohol ring… ☠️☠️☠️ shit gets crazy real quick. For reference I’m talking about phenol (an altered benzene), another interesting chemical to look at the molecular orbital model is ferrocene(it’s an iron benzene sandwhich)

@user-ug5sb6qg1u

2 ай бұрын

I once ordered an iron benzene sandwich at Subway, they even added extra pickles.

Great video with an intriguing method. As a home chemist, I will certainly be trying this method.

I love this channel. Thanks for being you, Nile Red.

this guy makes the best chemical videos on KZread

keep the video's comming, i really enjoy watching them.thanks !

I respect you because you are sharing knowledge. That's it! :)

This is a great video detailing extraction methods that goes over some important stuff, thanks for posting it.

@NileRed

8 жыл бұрын

+benJAMIN536 I am glad you enjoyed it!

@yellowgoose5043

4 жыл бұрын

@@NileRed nilered, let's hope you never get taken down by the "great" communist KZread. :) You are an amazing person and keep it up man, even tho I'm replying to an old comment idc. Lol

@supersophisticated9943

2 жыл бұрын

@@yellowgoose5043 If KZread is communist then I'm a frog stuck in a tall tower. /m

@VirtanenDK

2 жыл бұрын

@Super Sophisticated He's a flat-earth believer to lol. KZread is 100%, not Communist. Google is such a greedy company. Just the earnings of KZread, are huge. Some people are getting strikes all the time, or have huge problems with the algorithm. Some have lost their channel to hackers, and KZread has resolved nothing. I like to watch KZread videos. I feel I am paying for the content (but not to the right people). I sit through bad commercials, Google has probably sold my addi, many times over. Today i use a VPN, wonder why, i didn't do that before. Sorry for the long comment, but i don't like the way KZread is doing things.

@user-in8bz3kd7d

4 ай бұрын

​@@NileRedBro, have you ever made oxytocin? I'm very curious about this. How is it extracted from the ergot fungus? I really want to extract it myself. Can you teach me?

How to extract DMT: a step-by-step guide **Please spread this information as far and wide as possible; everybody deserves to know.** **Materials:** \- 100g powdered mimosa hostilis, acacia confusa, or acacia acuminata root bark \- 100ml 5% acetic acid (distilled white vinegar) \- 200ml nonpolar solvent (naphtha VM&P OR xylene) \- 1800ml distilled water \- 120g sodium hydroxide (lye) \- 140g sodium chloride (deiodized salt) \- Large glass pipette (with small tip) \- Milligram scale (to weigh product) \- Flat-top scale (to weigh bark) \- 4000ml glass mason jar \- 500ml glass beaker \- Glass bowl/dish (to freeze precipitate) \- Glass vial (to store product) \- Spash-proof goggles \- Lab coat OR long-sleeve attire \- Latex/rubber gloves \- Respirator OR dust mask **Procedure:** 1. Add 140g sodium chloride and 400ml distilled water to 500ml beaker to create a saturated saline solution (heat bath as necessary) 2. Place 100g powdered MHRB in mason jar 3. Add 1000ml distilled water and 100ml distilled white vinegar to mason jar 4. Stir every 5 minutes for 30 minutes 5. Soak for 30 minutes 6. Decant 400ml of saturated saline solution to mason jar 7. Add 120g sodium hydroxide and 400ml distilled water to 500ml beaker to create a basified solution 8. Decant 400ml of basified solution to mason jar 9. Stir every 5 minutes for 30 minutes 10. Soak for 30 minutes 11. Add 100ml nonpolar solvent 12. Stir every 15 minutes for 1 hour 13. Let layers separate for 24 hours 14. Use pipette to siphon the top layer (nonpolar solvent) into glass bowl/dish 15. Freeze at -18C (0F) for 24 hours until crystallization is finished 16. Pour excess solvent back into mason jar (add 50ml solvent as necessary) 17. Turn dish upside down and let crystals dry for 24 hours 18. Scape up crystals and place into glass vial, repeat steps 14-18 (3x) 19. Clean all glassware and properly dispose of leftover chemicals 20. Vaporize and inhale crystals to explore the inner workings of the universe **Safety Information:** * Always assume all chemicals are toxic * Use acetic acid to neutralize all sodium hydroxide spills * Extinguish any flames prior to beginning the procedure * If any chemicals come into contact with skin, neutralize and rinse skin with water * Fume hood or outbound-facing fan recommended * Do not consume product alongside lithium or tramadol * Consuming product may cause cosmic epiphanys **Good luck.

@HerbaMachina

4 жыл бұрын

This is an outdated method, you do not need to use Lye for the extraction

@mysteryY2K

4 жыл бұрын

Machina What base would you use personally?

@AnodyneHipsterInfluencer

4 жыл бұрын

Bad trips?

@mysteryY2K

4 жыл бұрын

Brady Hartsfield It's more for people that also enjoy chemistry as well as psychedelics. It's very much rewarding to consume a drug you extracted yourself. As for the chemicals, they'd likely be found at your local grocery store and hardware store.

@mysteryY2K

4 жыл бұрын

Josh Jones What about them?

Thank you for all the work you're doing, I find every video of yours extremely entertaining and informative. Keep up the great work! I have one question: Where do you generally find all the instructions for the synthes you do? I've tried googling some of the work you've done, but couldnt find any PDFs or anything alike. Would be happy to get a response.

@NileRed

8 жыл бұрын

+Fabian Müller It really really depends on what it is. I love it when I can find a PDF that students use for labs, but often that isn't the case. Depending on what it is, it is usually a mix of using Scifinder (paper search engine), reading forums like ScienceMadness, googling, searching google books, and using my own knowledge. I am going to try to post my sources better in the future.

@thespecialduck5030

2 жыл бұрын

@@NileRed lol i can hear him say what he typed

@takusaka3667

2 жыл бұрын

@@thespecialduck5030 lol, me too.

@redwithblue_dex

7 ай бұрын

Same lol​@@thespecialduck5030

To take out the color from the pills, you have to add some activated carbon and reach boiling point a few times. Filter it off while hot with a bed of celite and get rid of the activated carbon.

Note: when you got tensides you should always try breaking the emulsion (if it is one) or check for a helper substance which is in a tablet that can act as Emulgator. It’s important to remove Tensides first to avoid a low extraction rate

You're awesome! I am enamored with chemistry because of your videos. I wish you were my chemistry teacher in high school.

If my chemistry teachers had been even 1/10th as inspiring as your videos, I would have been much more interested in chemistry. I got As and learned everything they taught me, but never really cared about the possibilities. The worst chemistry teacher I had would just come in, write the text word-for-word from the textbook on the whiteboard as he spoke it, then he would call it a day. I remember labs where we collected data, messed something up, then did some creative math to work backwards to get to the desired result. I also remember splashing some pretty strong acid on my shirt and being embarrassed, I hid it and completed the lab while my shirt slowly dissolved. Those were the good old days!

I came here to learn how to extract pseudoephedrine from cold medicine.

@amkamomega

4 жыл бұрын

*Happy Jesse noises*

@i-use-arch-btw3954

4 жыл бұрын

Now you just need some red phosphorus.

@1ericcarter

4 жыл бұрын

Muriatic acid

@heezywrld

4 жыл бұрын

just get pseudoephedrine tablets bruh

@crf80fdarkdays

4 жыл бұрын

@@heezywrld can't do that in Australia bruh..

This is one of the most brilliant chemistry videos I've come across.

Thanks I will used this for prepping, turning spoil food into good food.

Nile red must be on several watchlists by now

I've always been wondering how to do this stuff myself! thanks!:)

@DejaStacy

10 ай бұрын

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

@DejaStacy

10 ай бұрын

Dude is on telegram and Instagram

@DejaStacy

10 ай бұрын

@pham_smart1

I will definitely be a patron soon. My neighbor had a thing for me and asked me one day "is there anything you don't know?" I did a quick inventory. Celestial mechanics, electronics and chemistry." So I took a summer coarse on astronomy at a local Community college, built my own telescope and could point out most of the constellations for the average lay person. I'm no Michio Kaku. I've been an auto/truck mechanic for over 15 years so I actually did know enough electronics to fix my car and I was an (real) electricians helper so I can do any home repair project all that's left is CHEMISTRY!!!! Bwahh ha ha haaaaa

@thatkindagirl777

6 жыл бұрын

cool story bro

@yahoomotherfkr5020

5 жыл бұрын

A whole year and the guy now works for space x

@tryphonunzouave8384

5 жыл бұрын

What's the point of this comment ? Why did you only list three things, do you know a lot about like... What proteins does a pigeon need in order to grow properly ? I guess not, nobody does, this is a shit example, fuck me

Welcome to the watchlist

I’m glad I found this channel 👌

...a spreadsheet. Good idea. Sweet vintage Visionware.

My day instantly gets better when I see a new Nile Red video. Also, do you think it's possible you could synthesize Menthol?

@NileRed

8 жыл бұрын

+Mr.chang cooler I appreciate the love! I have actually been looking into menthol. I think the synth is a little out of my ability for now though in terms of equipment and reagents.

@mrchangcooler

8 жыл бұрын

Nile Red That's too bad. And no problem, your videos are always fantastic.

@theCodyReeder

8 жыл бұрын

+Mr.chang cooler I guess I could give it a shot.

@mrchangcooler

8 жыл бұрын

***** I'd love to see the both of you give it a shot at some point. If you do give it a shot and you don't end up making a video on it, tell me how it went.

@alphamalewolf2616

8 жыл бұрын

+Cody'sLab didn't think i'd see you here either. xD how coincidental.

I find this so interesting. Pitty I didn't choose to do science in school. Thanks for the video.

It is so cool though how you are thinking. It has really opened my eyes to seeing all the chemicals that are in our everyday products we use. Anyone know a good channel with a chemistry background guy teaching you how to make safer alternatives to things like soap deodorant detergents and everyday products. Would like to rid the use of toxic products

Dear FBI, BATFE and DEA, I'm just having a binge of watching about extraction and drilling lowers simply because I'm bored and tired. Please don't break into my house.

man I supper when you had 3k subs now almost 20k! congrads!

@NileRed

8 жыл бұрын

+Zachmartus You are one of the originals! :)

@alanraza2570

4 жыл бұрын

NileRed now you have over a million subscribers wow

@progod6017

2 жыл бұрын

@@alanraza2570 3 mill

Videos like this were why I subbed.

This would make a great undergraduate guided discovery lab!

Please be a chemistry teacher if you're not already. You are amazing at explaining things.

How did you separate the povidone from the caffeine? They share the same solvents. Does the povidone have a lower boiling/evap temp and so was evaporated with the alcohol/water?

Man this channel is so awesome

@NileRed

8 жыл бұрын

+Clarence Keaton Thanks!

Thanks very much 4 this, NileRed

Amazing video, thank you :) As a side note, in tablets you can pretty much ignore everything except carbohydrates (such as lactose, starch, maltose, dextrose, cellulose etc.) other components (sometimes including active component) are present in very low concentrations, rarely more than 1%.

@NileRed

8 жыл бұрын

+Veo That is true, I should have actually mentioned that.

Clandestine chemistry. I FUCKIN LOVE IT.

@sinda1635

10 ай бұрын

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

@sinda1635

10 ай бұрын

Dude is on telegram and Instagram

@sinda1635

10 ай бұрын

@pham_smart1

learning to think for yourself is awesome

Very nice to see that you have thought about my acetone dry distillation idea :)

@NileRed

8 жыл бұрын

It's a good idea. So I'll try it out!

Brilliant video! These are some very useful tips! I have a couple questions: 1.) What camera do you use? 2.) Why is your youtube channel so awesome? Cheers from Canada.

@NileRed

8 жыл бұрын

1) canon 6D with the beautiful 24mm f2.8 lens. 2) thanks! :). I do my best

@ThePaulPyro

8 жыл бұрын

+Nile Red Spectacular quality, bravo! (I use my phone camera for my videos, works alright but some issues every once and a while.) And it is evident in your videos, you explain everything thoroughly. Proud subscriber :D

@NileRed

8 жыл бұрын

Thanks!

@astbrnrd

8 жыл бұрын

Hummm....so extracting lido hydrochloride IS A DIFFICULT task.... Or just out of that product you had at hand?? Interested in the science behind it to see if from 400ml of 4% lido HCL could be extracted from the bottles (50ml/40mg ea) to make at least 60-100ml of 10% lido HCL (hope that made sense). Second the awesome Chanel comment ;-)

@NileRed

8 жыл бұрын

I might in the future, but the yield just isn't amazing. And considering iodine isn't super hard to get off the internet, it is hard to justify a whole process. However, I might do it just as a matter of interest!

Hey. Love the chemistry videos, been marathoning them recently. Any chance you could do a video on how to recrystallize various substances (in the generality that you did in this video)?

@SoCalgardener

Жыл бұрын

Any luck lol

@motiv311

Жыл бұрын

end up with an HCL form of whateer you want, and then air dry it in a pyrex pan

As usual you are more than amazing thank you

I've watched your videos and think there great, i just wish i understood more of chemistry. thank you for the videos.

@NileRed

8 жыл бұрын

+Dar Cam Just keep reading and your knowledge will grow!

I was pretty fed up with lactose in my medication so I started to extract the Temazepam and it forms such lovely crystals after an ethanol or methanol extraction but I feel like it kills the potency, perhaps during the drying stage in which I left it covered with some paper towel overnight for all of the solvent to evaporate so I never really continued doing so but the crystals which form are very beautiful and there is something about having crystals of Temazepam which made me a little giddy inside.

@randykitchleburger2780

Жыл бұрын

Sounds fun

@Beau1990

11 ай бұрын

Could you not just cold wash valium and filter it through coffee filters the same way you can will Forte's. Also can tapentadol be purified through the same methods,? Any input appreciated.

Are you making fake cocaine ? I mean cafeine and lidocaine… ._.

@GabrielDipo

4 жыл бұрын

Hmmmm

@kelvinzenteno3945

4 жыл бұрын

What's other anesthetic stimulant would he be making?

@lorexcold

3 жыл бұрын

@@kelvinzenteno3945 amphetamien

@potatomanure3773

3 жыл бұрын

@@lorexcold amphetamine isnt an anesthetic

@aidanirelan9423

3 жыл бұрын

Potatomanure it’s not, but lidocaine is

Thank you so much, you are the best.

amazing video, very well done

Excellent video as always. I plan on synthesizing caffeine from uracil in the lab later this week. I have also heard of it being synthesized from theobromine, though I do not have access to that reagent so I've decided upon the uracil method. Any plans to do a caffeine synthesis video, rather than extraction? Cheers from Ontario.

@NileRed

8 жыл бұрын

Actually I do plan to make it from theobromine. It should be pretty easy to do. I was going to try to extract theorbromine from cocoa and make caffeine. But I don't know if its possible to get a clean extraction. Otherwise I can buy theobromine and synthesize it. Going from uracil is also an interesting method.

@JeffandJake

8 жыл бұрын

If you have a chance, I recommend checking out the protocol available online for the uracil method. It's a far newer procedure compared to the theobromine method, and yields seem to be in the mid 80s which is definitely more promising than the comparatively low yield from theobromine. Either way, looking forward to your video on caffeine synthesis.

@NileRed

8 жыл бұрын

The theobromine method has the advantage of being like one step. I just found that uracil can be made from maleic acid and urea, very interesting. This could be a nice ground up synthesis. Is there an easy OTC source of maleic acid/anhydride?

@JeffandJake

8 жыл бұрын

+Nile Red As far as I know, maleic anhydride/acid is used in fuels and plastic polymers, so I imagine the extraction would be fairly complex as there's a huge number of interacting molecules in there. I know that you can produce maleic anhydride through oxidation of benzene or butane, check out "A study of the catalytic oxidation of benzene to maleic anhydride" by Basil Dmuchovsky et al. Urea is obviously available readily through your lab's supply chain or can be extracted from urine (though I don't know if that would make for a good video...). Do you not have access to uracil? It's fairly inexpensive at around $0.80/g CAD, not sure if you've got it in stock though. I'm in the process of acquiring equipment to perform the synthesis, I work in a molecular bio lab so I'll be borrowing some glassware that we haven't got on hand. Also, looking forward to your luminol video, we use that reagent quite often in lab.

@NileRed

8 жыл бұрын

Cool thanks for the info. I am getting my urea from instant cold packs (i do have reagent grade urea though). Let me know how your synthesis goes! I am very interested.

This is a super helpful video! Now we can-

@DejaStacy

10 ай бұрын

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

@DejaStacy

10 ай бұрын

Dude is on telegram and Instagram

@DejaStacy

10 ай бұрын

@pham_smart1

Summarily: Nilered is one of the best

i feel safer knowing nile is teaching

but what do you do if you cannot find solubility data for what you are extracting? (for example certain cellulases) do you just try random solvents and use the extract on cellulose until you see which one breaks down cellulose and use that to determine which solution had the enzyme dissolved in it? or would you just extract everything else until only that remains? also is there one easy way to determine a chemicals solubility or is that impossible due to stearic forces ect?

Thanks. I was searching for this to learn how to extract phenylephrine from cold medicine. In my country you can only find it OTC combined with acetaminophen . I can stand the pain, fever and headaches during colds but the stuffy nose kills me and I've abused nasal sprays too much...

@andrewmichaels6298

2 жыл бұрын

Hahahahahahaja phenylephrine isn't a good "precursor" for your cold... stick to pseudo

@timwheeler1503

Жыл бұрын

@@andrewmichaels6298 🤣🤣🤣

@coolfiretire12

Жыл бұрын

hahajahahajhajahajajajajahajahahahahahhahjahaja owned by andrew michaels (i dont know anything about chemistry)

@WeighedWilson

9 ай бұрын

Try green chile. The hotter the better to clear sinuses. Eat it, don't inhale it.

Very Impressive. Personally I don't have a chemistry set. ;) Great job man.

This is really useful

I love watching a Canadian chemist make videos. Shopper's Drug Mart? I know just where to find these ingredients!

@DejaStacy

10 ай бұрын

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

@DejaStacy

10 ай бұрын

Dude is on telegram and Instagram

@DejaStacy

10 ай бұрын

@pham_smart1

A little something from eMedicine Emergency: The symptoms of lidocaine toxicity tend to follow a predictable progression. The toxicity begins with numbness of the tongue, lightheadedness, and visual disturbances and progresses to muscle twitching, unconsciousness, and seizures, then coma, respiratory arrest, and cardiovascular depression. CNS toxicity: When the lidocaine dose is increased from 1 mg/kg to 1.5 mg/kg, the risk of CNS toxicity increases from 10% to 80%. Symptoms include the following: o Lightheadedness, dizziness o Visual disturbance o Headache o Perioral tingling, numbness or tingling of tongue o Sedation o Impaired concentration o Dysarthria o Tinnitus o Metallic taste o Muscular twitching, tremors With progression of toxicity, the patient may experience tonic-clonic seizures and, eventually, unconsciousness and coma. Seizures generally do not occur with lidocaine levels of less than 10 mcg/mL. Cardiovascular: Excessive lidocaine concentration can cause cardiovascular toxicity, although this is less common than CNS toxicity. Lidocaine is somewhat less cardiotoxic than lipophilic local anesthetics such as bupivacaine. Risk of cardiac toxicity is greatest in those patients with underlying cardiac conduction problems or after myocardial infarction. Potential cardiovascular effects include the following: Negative inotropic effects Effects on vascular tone (with low doses having vasoconstrictive effects and higher doses causing relaxation of vascular smooth muscle) Effects on cardiac conduction include widened PR interval, widened QRS duration, sinus tachycardia sinus arrest, and partial or complete atrioventricular dissociation. Cardiac arrest has been reported after intraurethral administration of lidocaine. Cardiac toxicity is potentiated by acidosis, hypercapnia, and hypoxia, which worsen cardiac suppression and increase the chance of arrhythmia. This is important to consider since seizure makes this metabolic picture more likely. Plasma lidocaine levels of less than 5 mcg/mL are unlikely to have cardiovascular toxicities. Levels of 5-10 mcg/mL can cause hypotension by inducing both cardiac suppression and vascular smooth muscle relaxation. Levels of more than 30 mcg/mL are associated with cardiovascular collapse. CNS symptoms may be masked in patients premedicated with anticonvulsants such as benzodiazepines or barbiturates. The first sign of toxicity in these premedicated patients may be cardiovascular system (CVS) depression. When blood levels are high enough to block inhibitory and excitatory pathways, convulsions cease and the patient experiences respiratory depression or arrest and cardiovascular depression. Large bolus injections may increase peak anesthetic levels to the point where the CNS and CVS are simultaneously affected. I'm gonna do eeeeet !!!!

Some of these over-the-counter extractions are surprisingly simple. For most dextromethorphan-hydrobromide products, all you need is baking soda, purified benzene and Vitamin C in an easily water-soluble form. A kitchen will do for a lab, since you're likely to find everything you need there.

Dayum. ive been looking for this information.

You should make a video on how to clean all the garbage and poisons out of our prescription medications. Everyone needs to know this life saving knowledge

@leslieanne447

2 жыл бұрын

You can usually figure of what in nature is being mimicked and go from there. Natural plants and herbs for one example cannot be patented. It's easier to start with that and go the other way..Tinctures and extracts etc.

Hey Nile Red, where do you get the procedures and steps and general ideas for videos from? Any online sources? I'm curious because I'd like to start doing some more types of this work in my lab (as opposed to class "kitchen" chemistry). Thanks!

@NileRed

8 жыл бұрын

I get them from papers, forums and other procedures. Some are just made up by me. It really depends on what I do.

@andrewfields9987

8 жыл бұрын

Would it be possible for you to link some of those forums or papers? It's cool if you don't, just wondering!

@NileRed

8 жыл бұрын

Off the top of my head, I can't think of many. I am looking to do this eventually though: www.sciencemadness.org/whisper/viewthread.php?tid=13130 The papers I will link when it is relevant to the video, but I dont have the links on me. You also wont be able to read the paper unless you have some sort of paid access to it.

brilliant stuff again

edit: lot it was late nice work nile red!

@alexleyendaa909

8 жыл бұрын

+TheZabbiemaster stfu

Could you do a video about extracting alkaloids from plants (ex. Datura)?

@kilian8250

3 жыл бұрын

It’s the same idea

Sorry for my ignorance but, exactly, what separates the povidone from the caffeine if they are diluted together? If you evaporate the dcm, supposedly you get not only caffeine but also povidone in the final results right?

@shansra11

8 жыл бұрын

When you recrystallize the caffeine and povidone, you slowly lower the temperature so that the caffeine gets less soluble and precipitates out. The povidone doesnt precipitate out because there is not that much of it so it is more soluble.

@MaachoMaan

7 жыл бұрын

The povidone is used specifically to inhibit recrystallization, so I'm not thinkin' this works!

Good explain 💪 continues

Cool video! I'd love to do these experiments at home but I don't have any of the required apparatus. Cheers from Toronto.

@NileRed

8 жыл бұрын

+Blessman Fred Start small! Buy some small glassware and work your way up. It is slow, but youll get there.

Awesome video, chemistry is amazing. You should make a video extracting MDMA/MDA from ecstasy tablets! That'd be super dopee.

@TetraSamurai

7 жыл бұрын

MDMA is ecstasy, no idea why people think ecstasy is a combination of different drugs.

@thatkindagirl777

6 жыл бұрын

you have no idea wtf youre saying dude dont do drugs keep watching you tube buddy

@GogiRegion

6 жыл бұрын

(+BaldManLogan) You really don’t know how the black market works, do you? Ecstasy is classically MDMA, but tends to have multiple things in it. Oftentimes meth is a main ingredient because with no tolerance, it has near identical effects orally (there have been studies on it for psych help [like MDMA for PTSD could have meth for PTSD as a possible substitute). Meth is found more often than MDMA in ecstasy. Another common combination is MDA and MDMA, which is more neurotoxic (you should take it less often to be safe), but considered more euphoric. Just because one thing claims to be something doesn’t mean it is that when it’s illegal. For example people being given fentanyl as heroin.

@SpaghetteronmySweaty

5 жыл бұрын

@@GogiRegion come to europe where youre gaunteed to only find inactive ingredients in your pill along with high doses of pure mdma

@maggiep9007

5 жыл бұрын

Spaghetter on my Sweaty There are no guarantees unless you can sue the maker if a pill gives you aids.

I'm so confused. How would recrystallising the caffeine purify it? I thought the povidone was still in the solution with it. Wouldn't it just recrystallise both the povidone and the caffeine?

@babihute97

3 жыл бұрын

Hi, i'm try to answer ur question about understanding the recrystallization. From the chart given, you can see that the povidon and caffeine both soluble in water, BUT, in cold water the solubility of caffeine drop to 2g/100ml, meaning, if both the pv and cf is soluble in hot water ,when the temperature goes down its suppose to retain the pv inside the water while the cf solubility decrease and recrystallised. therefore, pv fully dissolved in ther water while cf recrystallised and filter off. yield lost of caffeine is because after each recrystallization there are still some caffeine will dissolve in the water. Any recrystallization step will lead to a lost

@macon8638

2 жыл бұрын

@@babihute97 cheers

Thank you I was just going to extract a chemical from a random item from the Walmart counter.

Love NileRed ❤️

how did he get rid of the povidone as it was soluble in the same things as caffeine

@francisnaveen9041

3 жыл бұрын

He recrystallised it from water. Only caffeine is soluble in hot water while providone is not.

Please excuse my ignorance, but if the povidone is also soluble in dcm, what stops it from recrystalizing out alongside the caffeine?

@chrish.942

5 жыл бұрын

incredibly late answer, it comes out alongside the caffeine after the DCM extraction, but it stays in solution after recrystallisation because it is soluble in cold water, unlike caffeine, which precipitates as it cools down

@hondo190

5 жыл бұрын

@@chrish.942 late, but exactly what I wanted to know. So ty

@leandroemmanuelalvarez6439

5 жыл бұрын

@@chrish.942 also he forgot to take out the color with activated carbon and filter it off with celite

@steveanderson971

5 жыл бұрын

You should look into an Acid/base extraction. Much better but takes a little more chemical knowledge

@travissmith5037

4 жыл бұрын

Could you recommend what to use taking out naloxone from burp in suboxone ..that shot is unhealthy it does exact opposite of the claims...and docs hands are tied to wrote subutex it is formed without added killer naloxone nothing locks onmnmm

All these vids make me nostalgic for the 90's when we used to use acetone to clean our meth, doing repeated washes & filtration cycles using coffee filters. When it was clean enough we'd boil it in acetone and at "just zee right moment" add a drop of denatured alcohol ET VOILA ....she goes solid ..like a measuring cup with frozen water. Boiling acetone is a tad risky ...it creates an odourless FLAMMABLE cloud in the middle of the room. Someone walks in with a lit cigarette and doesn't know it until they reach the cloud. ....LoL ...and THAT'S a mess I've never had to clean up xoxo ...cue song "Those Were The Days..."

Interesting video Made me wonder if it’s easy to isolate methadone powder from the syrup it comes in Any ideas?

how about an extraction of Dimethyltryptamine

@xxxSolidShrimpxxx

8 жыл бұрын

+dutstinroach i lol'd

@rangerfox532

8 жыл бұрын

+dutstinroach Mimosa Hostilis works great and is fairly easy to get. I would love to see him extract it also, I have in the past but couldn't get a good yield do to lack of equipment

@dutstinroach

8 жыл бұрын

+killer rgm yeah I tried an extraction once using acacia confusia but like you did not get much and what I did get was oxidized and not very potent

@TetraSamurai

7 жыл бұрын

Good luck, near impossible to produce pure dmt unless you have university level knowledge in chemistry

@Domenic367

7 жыл бұрын

he said Dimethyltryptamine not Dextromethorphan.

DEA has entered the chat👮👀

Do you have a recommendation of a cheap starter kit or list of glassware to get me started? Like a used chemistry wholesaler from a highschool maybe? I'm looking to do some simple to advanced chemistry experiments following your videos and some other KZreadrs. Thanks!

Good video and talking about extractions would you by chance know how to extract the magnesium out of the dead sea salts when making ormus

Hey, nice video! May you try extracting cyanide from apple seeds? I think it would be a cool idea. Thanks!

@supersophisticated9943

2 жыл бұрын

Don't they combine with your body to make the hydrogen cyanide? I don't think it's already cyanide. I also could've sworn that was just in stone fruits.

@toxicpsychotic6356

2 жыл бұрын

​@@supersophisticated9943 The cyanide in apple seeds is in the form of amygdalin, a molecule that contains hydrogen and a cyanide group. It only needs to be broken apart in order to create hydrogen cyanide.

Could you please tell me how we extract Latex from cocaine?

@vadaza

11 ай бұрын

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

@vadaza

11 ай бұрын

Dude is on telegram and Instagram

@vadaza

11 ай бұрын

@pham_smart1

@coleflynn7538

2 ай бұрын

uncle escobar gave me a plastic chair...

@Haagsebluf

Ай бұрын

This comment is underrated ;P cheers

Can you make a video showing how you come up with the amounts of things to use?

Hey guys, I have 2 questions. Ive been trying to make potassium chlorate from 14% sodium hypochlorate but for some reason im doing stuff wrong. Ive tried 7 times and my only successful run yielded about 3 grams. I was also trying to make nitric acid with HCl copper and a nitrate salt (im only 15 so I dont own a fractional distillation apparatus) from an Erlenmeyer flask with a a tube connected to it. So ive successfully gotten NO2 gas but when I bubble it in water I just get a blue solution( witch im thinking is copper sulfate).And doesnt react whatsoever with copper or silver but it bubble when it comes in contact with lime. So anyone have any ideas on whats up with that?

@pietrotettamanti7239

7 жыл бұрын

A black hole you are doing things completely wrong. you need ONLY a nitrate salt and a strong acid. copper isn't required. no, you can't use HCl because you would boil away it with the nitric acid. the reaction HCl+KNO3------>KCl+HNO3 is an equilibrium. this means that the products can also react to reform the reactants. to fix this you have to boil off one of the products, so they can't react. this can't be done with HCl because you would boil away it first than the nitric acid. you have to use H2SO4 and KNO3. H2SO4 boiling point is much higher than nitric acid one. you produced NO2 because the nitric acid reacted with the copper. why did you put the copper in that reaction? and why did you think that the blue solution was copper sulphate? there wasn't sulphur in your reactants, how could the sulphate be there? the solution was copper nitrate. for the potassium chlorate i haven't an answer, i don't know your procedure. one last thing to point out: nitric acid, potassium chlorate... even the dumbest chemist would understand what you want to do. I know your reasons, as i am very similar to you and at our age (i'm 16) everything that explodes or burns is intresting. but, trust me, you have to study first. chemistry isn't only breaking bad and explosives. you can't just mix together some shit and watch what happens without understanding as you did with the nitric acid. you will seriously harm yourself in a short amount of time. you can't just study a little bit of chemistry and then searching the procedures on internet. you have to fully learn chemistry and then you will start studying that amazing the branch of explosives. but it is a branch, not the centre. maybe you won't take me seriously because i'm 16. i started studying it 2 years ago and now i'm 2nd at the chemistry games in my country (italy). but I studied hard and i'm not even near to the half of the road. i'm a real chemistry nerd. take chemistry a little more seriously pls

@MGSLurmey

6 жыл бұрын

Chemistry is dangerous, no chemical reactions should be attempted without properly knowing and fully understanding the reactions taking place. I heavily suggest doing a course on chemistry before undertaking large projects.

So how would a guy clean fats from naptha so it can be resused for say an alkoid extraction??haha. Loving your videos. Always wanted to go chem, but life had other plans

@HollywoodJoeTussing

7 жыл бұрын

I was thinking charcoal but then i found your cool ass page

Happy trails.

Could you make a video on diisopropylamine and diisopropylamide, as this is one of the common bases in encountered in enolate chemistry.

+Nile Red You are extracting lidocaine form personal lubricant. Aren't you?

@calebbadger

8 жыл бұрын

+The OpenSourceHuman Project Topical lidocaine-prilocaine spray for the treatment of premature ejaculation:

@QuestWilliams

8 жыл бұрын

Bacon Sanderson Well it does have a much shorter ingredient list.

@NileRed

8 жыл бұрын

+The OpenSourceHuman Project I will 99% confirm that.

@RKKDesign

6 жыл бұрын

I was going to guess hemroid cream....smh

Love your videos. Please consider doing a video about extracting nicotine from cigarettes. Possibly very practical for people wanting to make their own vaping liquids.

@nunyabiznez6381

8 жыл бұрын

+XCyclonusX If one were to do that it would be less expensive to purchase raw tobacco for that process. Plus the tax would be lower in most cases. many states impose an extremely high tax on finished tobacco products but not nearly as much on raw tobacco leaves. As a business venture those substances are extremely lucrative. In my medium size city there are a dozen separate businesses solely engaged in the manufacture of vaping liquids and most are relatively small start-ups. One started three years ago with just the owner. He has over 100 employees today and has to expand into larger facilities three times since founding. I'm not personally interested in this particular industry but it is definitely a lucrative business and with a huge potential for expansion. If you are producing your own for personal consumption you should also know that you could grow your own legally. It's just another plant and relatively easy to grow. All you need is some land. Or you can grow it in flower pots if you don't own land.

@rickautry2759

8 жыл бұрын

Practical, but possibly fatal if somebody misplaced a decimal point. I've been using crap pipe tobacco soaked in water overnight as an insecticide for years. The liquid makes a kickass spray, and the soggy tobacco leaves around my tomatoes are for the slugs. (Don't say it- Tomacco! No, there's no murderous goats around yet!)

@TetraSamurai

7 жыл бұрын

XCyclonusX or just buy nicotine online lmao. You could also extract it from nicotine patches.

@frankatchison1617

6 жыл бұрын

XCyclonusX I am Pretty sure pure ethanol will release nicotine from tobacco but How to measure the mic's or mill's is beyond me.

Thank you I am subscribing have a nice day bye

any advice on where to start as a beginner. what glass wear is needed etc

Title Edit: "Breaking Bored staring HeisenDork"

ACETONE FROM CACLIUM ACETATE !!

@RollLandOh08

8 жыл бұрын

+Gonzalo Boneu damn

@NileRed

8 жыл бұрын

+Gonzalo Boneu I will be making it from sodium acetate I think. It is easier to get.

@gonzaloboneu8329

8 жыл бұрын

Holy funking god, My second favorite Chemistry channel Answered me. I'm god today B|

@NileRed

8 жыл бұрын

haha I am glad to help any way i can

@gonzaloboneu8329

8 жыл бұрын

Keep on the good chemistry then :D and Thank's . Greetings from Argentina !!

now i got to find smerfs thanks ^_^

thank you

will this work for dxm asking for a friend

@aidonwelsh8968

4 жыл бұрын

greetings fellow robotripper

@bigguyzack

4 жыл бұрын

@@aidonwelsh8968 greetings

@heezywrld

4 жыл бұрын

yooo imagine snorting pure dxm

@iEatLife

4 жыл бұрын

nopenruu I don’t have to just did it I’ll update you how it was in a few ☺️

@valforatlas

4 жыл бұрын

Lane Byers how was it?