How The Gut Microbiota Affects Our Health with Dr. Erica & Dr. Justin Sonnenburg
Dr. Justin Sonnenburg is an associate professor of microbiology and immunology at Stanford and Dr. Erica Sonnenburg is a senior research scientist in the Sonnenburg lab where they the research many aspects the interaction between diet with the 100 trillion or so bacteria in the gut (specifically the colon) and how this impacts the health of the host (which in this case is a laboratory research mouse). In this episode we discuss the pivotal role fiber plays in fueling good bacteria in the gut to produce compounds that regulate the immune system including increasing the number of T regulatory cells, which are specialized types of immune cells that keep the immune system in check and prevent autoimmune responses, and how these compounds also increase other types of blood cells in the body in a process known as hematopoiesis. We also talk about how the lack of fiber in the typical American diet actually starves these good bacteria of their food. This has an effect not only on the immune system and autoimmune diseases but also results in the breakdown of the gut barrier, which leads to widespread inflammation and inflammatory diseases. Lastly, in this podcast, Dr. Erica Sonnenburg talks about how C-sections, have a negative effect on the infant’s gut due to the lack of exposure to bacteria present in the mother’s vaginal canal, and how the use of formula deprives the infant not only from the good bacteria present in Mom’s gut but also from special carbohydrates in breast milk that are good for the infant gut flora known as HMOs or human milk oligosaccharides.
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"The Good Gut" Book: www.amazon.com/...
The Sonnenburg Lab: sonnenburglab.s...
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Chaptering
00:00:00 - Introduction
00:00:36 - Microbiome
00:05:21 - Diet
00:11:41 - Inflammation and autoimmunity
00:15:49 - Fiber
00:22:19 - Artificial sugars
00:24:33 - Antibiotics
00:28:53 - Probiotics
00:35:12 - Microbiome development
00:39:15 - Pregnancy
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#microbiome #guthealth #inflammation
Пікірлер: 362
I read their first book. Then I tried something. I fasted for 72 hours to clear out and reset my digestive system. Then, I followed through with changes in my diet according to the Sonnenburgs. Breaking my fast, I shifted my intake to a large amounts of high fiber, cruciferous vegetables and large daily amount fermented foods along with olive oil, sardines and citrus. It didn't take long to start feeling effects. Deeper and restful sleep with a lot of vivid dreams. While eating I would feel satiated. All inflammation seem to have disappeared. My energy was up, but my got mind real calm. Emotionally, I would say things are going pretty well. I was surprised that it didn't take long. This couple here is a national treasure. I think the human race needs to fix their food and they have a lot of good information on how. I recommend watching this and learning more.
@augustbramming4926
2 жыл бұрын
incredible, thanks for sharing.
I love the way you actually listen and keep attentive and silent during interviews. Nothing turns me off more than people who keep on cutting into an experts statements, which happens in an overwhelming majority of interviews. Keep it up and God bless you for the good and useful work you do.
Dear Dr Patrick. I just wanted to say a big thank you for all of your videos. I love your style and the delivery of the information you share. Truly an inspiration, thank you. Matthew.
@morganboudrou7097
5 жыл бұрын
River Star/7fi
Just wanted add a note about why some women don’t breastfeed because I’m part of a large community of women who had to use formula because their body’s didn’t work for them. Some women, like me, try everything imaginable and still aren’t able to breastfeed because for some reason my body didn’t develop the glandular tissue during puberty/pregnancy needed to make milk. I spent 10 weeks using a supplemental nursing system and pumping every 2 hours but still wasn’t able to produce even close to 1oz total, both sides, in a 24 hr period. It was probably the most heartbreaking experience of my life. I really wish someone would start researching why a seemingly healthy women like me would have an issue like this instead of just assuming women use formula because they find it easier.
Heredity,environment, life style and diet are the basics FOR A LONG LIFE. H L Gould MD AGE 90+
This episode has a transcript and show notes! View them at foundmyfitness.com/episodes/the-sonnenburgs Here are just a couple of the great quotes from this amazing interview: "We're not just this collection of human cells. We're in fact more like a tube of human cells that houses this incredibly complex and dynamic ecosystem of microbes, and what we're finding is that these microbes are wired into pretty much all aspects of our biology.“ “Yeah, so the average American is eating around 10 to 15 grams of dietary fiber per day. The U.S. government recommends that we eat more along the lines of 30 to 35. So just by that measure, we're pretty fiber-deprived. If you look at these traditional populations that we study in our lab, these hunter-gatherers that lived in Tanzania, they're eating on the order of 100 to 150 grams of dietary fiber per day." "And so as we don't consume enough dietary fiber, these microbes become closer to our mucus lining. They're eating that food because that's all they have to eat, and they're inching ever closer to our own epithelial cells. And that creates a situation in which the human aspect of our GI tract and the microbial aspect, that fence that keeps them separated starts thinning and setting up a scenario where our immune system now can start overreacting to these microbes encroaching and these microbes potentially get a little more aggressive because they're lacking in the food that they require." Hope you enjoy the episode! Make sure to check out the Sonnenburg's book at amzn.to/2zKrRhg.
@ianoji
5 жыл бұрын
you should pin/sticky this, or just type it into the video description!
21:21 talks about foods we should eat
@MNInvestments
4 жыл бұрын
Rizwan Sikander thank you
@joshharvey9687
3 жыл бұрын
🙏
One inexpensive and effective probiotic is Sauerkraut. I eat 1 to 2 ounces each day. I buy it at a Polish deli that makes it in-house.
@ajc484
5 жыл бұрын
Three One I know this is two years old but sauerkraut is super easy to make yourself too!
@MrChiangching
5 жыл бұрын
@@ajc484 Yep, I just started a batch.
@kurtdriver
5 жыл бұрын
I get kimchi at a Korean store in town, can't help adding vegetables to it though. Carrots, broccoli, cauliflower, onion, garlic, ginger, lentils, all good stuff.
@billytheweasel
5 жыл бұрын
I eat 2 tablespoons of Bubbies sauerkraut on Sat & Sun. It tastes good! I rarely eat Kimche, I just don't like it.
@billytheweasel
5 жыл бұрын
@Evoke Spirit Yep but ours doesn't taste anything like Bubbies!
Love Dr. Rhonda's interviews. The gut, general nutrition/diet type, exercise, sleep and stress management are all interesting subjects which are crucial in striving for longevity. Asking all the right questions. Keep them coming!! :-)
Your excellent videos have been very valuable in beginning to understand the complexity of nutrition. The production has been universally excellent. I especially like the screen notes that define and expand on the concepts verbally presented without distraction from the conversation. Great job!
I can’t get enough of your videos. I’m learning so much!
this is such a common sense approach to gut health...take more fibers which is really what we said 10 years ago but we did not link to parasites. more to learn. I appreciate you all!!! thank you
This is so important! Most people don't even understand how gut health is directly connected to good mental health too! Ever since I started taking Florajen Probiotics I stopped feeling bloated and my mood swings have gotten so much better!!
We ferment tons of veggies and eat some every day. Right now I have Vidalia onions fermenting, fennel, and garlic scapes. We eat our cabbage ferment all winter. All made from our local organic farmer's produce. They should talk about how often one has bowel movements on a fiber rich diet vs. the Standard American Diet (aka SAD.) There is zero constipation in our house. I believe this is a good marker of how much fiber one is getting.
@christyhicks6350
6 жыл бұрын
Amy Virginia you ferment the onions, fennel and garlic together? I’ve Just started fermenting and looking for ideas
This information will revolutionize your life. I highly recommend it. For people who suffer from anxiety and PTSD this can be one of the keys that turns the lock on controlling and overcoming a traumatic past. When I began remembering what had happened to me as a child I was overcome with panic attacks. I don't like taking medication and I was already very involved with organic foods so I looked for a way to use less medication (which I used only for panic attacks) and find natural remedies that would help stop the emotional pain. I used therapy as well and it was a real ordeal getting through the memories. I have a degree in creative writing so it was natural for me to write a book about my experiences. When I started being open about what happened to me the panic came back and horrible dreams with it. I read about probiotics and started using good ones from a good source. I found that the probiotics reduced the panic attacks. When I was anxious I took one and sometimes the anxiety vanished. Sharing intimate and terrifying experiences is painful and frightening and that is why so few people do it. It is important to share with someone even if you don't go public like I did. My book can also help survivors and those who are involved with them. It is "The Remembered Self: A Journey into the Heart of the Beast". I am MJ Payne and you can contact me @MJPayneAuthor on twitter. Remember to take care of yourself and don't bury stressful life events, work to overcome them. This information on your gut will help heal your gut feelings. Love to you all.
Dr. Patrick is absolutely brilliant! I have a PhD in Biology and wish I had taken classes from her...thank goodness she posts these wonderful interviews with other brilliant researchers.
Thank you for your contribution and for your friends from Stanford. We are to each other when we are living in this world.
@OswaldDigestiveClinic
3 жыл бұрын
If you enjoyed this video, you may also want to know that probiotics are microorganisms that are shown to provide a health benefit to the host, when provided in adequate amounts. So dosage is important!
Wonderful video! I have been trying to figure out why I keep getting colds and coughs numerous times a year. I think it’s in part because I’m not eating enough fiber and feeding my microbiome. Thank you so much for all this great information.
Great video, thank you. This year I have stated taking Kefir on daily basis. It has significantly improved my health. The true test will come in march when allergy season is in full swing. I started taking kefir in the summer and so far, it has been pretty good. I don't use store-bought Kefir, I make it at home with organic whole milk.
@rubinsteinway
4 жыл бұрын
Wonderful to hear you're making homemade organic, whole milk kefir! I too started making kefir about two months ago and just made my first kefir using raw milk from grass fed cows. Am also sharing kefir grains with friends/family and sharing the benefits of kefir. The gift of health is a great gift indeed! Great video!
And that's why in India we have, in our culture and tradition, recipes that revolve around seasons, rituals, and festivals, that give us variety in our diet. Our grandparents used to eat that way....and I am talking about just 30-40 years ago. When the British came to India, they brought with them their English way of eating. They introduced black tea and pastries and scones. And from there, the indigenous population thought that that is what the diet should be. Especially in the affluent population who could afford these new types of foods. And still it has not stopped, because now India has McDonalds and Dominoes everywhere. Most of the people eat for taste, and not for what is good for them. New generation have too much work stress, and so eating out has become more prevalent. But still take away message is that it is in our hands to make good choices when it comes to diet, and we should make wise choices, especially when, after this wonderful talk, we know what is good for us. Thank you so much for this lecture. Would love to be part of your research and studies!!
@KalpanaMD
6 жыл бұрын
Type 2 diabetes and Colitis are becoming prevalent in India too. Arthritis too! And Asthma and Bronchitis can be due to just too much air pollution, especially in big cities.
Congratulations! Very nice talk for general public and for biologists as well! 💕💕
We are more microbial than we are human now that explains everything !
Great, I hpe you have more interviews on this topic. And how syndromes and autoimmune can proceed to heal.
Who's the person with the 1 down vote, was it because of the crooked picture in the background? I kinda hear ya, but come on.
@jessicalt4121
6 жыл бұрын
Ausare911 ha!!! I love that picture and the plant that looks like a tree. Scientists are down to earth which I admire.... less concerned with superficial things.
@shellabella8625
6 жыл бұрын
Lmao!
@kurtdriver
5 жыл бұрын
I like that tilted picture; it's called gravity.
@billytheweasel
5 жыл бұрын
ok NOW I can't take my eyes off that picture...
@RealHankShill
5 жыл бұрын
The picture is not crooked, well not very much, the camera is. Its perspective. You can see it everywhere in the frame. Its what happens when the camera sensor is not square to the room, the room gets distorted.
It's great that the research continues and gets to the public. I studied this before Rhonda was born, back in the 80's.
The text which is embedded in the video is very helpful. I like to keep annotations on. Be careful not to have the two overlay, i.e. have the annotations asking for likes and subscribes only when there is no video text. btw - another great video. Thank you.
As I am learning about how the gut micro biome works, I am both encouraged and discouraged. I have advanced Crohns, and have had 15 surgeries including having my entire colon removed. I have a permanent ostomy bag. I’m trying my best to make the right choices, but does my body even have the ability to benefit from those choices without a colon? How can I help support my immune system without a colon? I consume a lot of fiber in different ways, I consume loads of crucifer oils vegetables that I spent a lot of time preparing so that I am even able to consume them. I am gluten, dairy and sugar free. But alas, my autoimmune issues will not go away. I wish there was research about how the micro biome works in people who have had similar surgical interventions as me.
Great interview Dr. Rhonda! I have a question request for a future interview. Calorie restriction has been found to improve health and longevity across a variety of species. I would be curious to learn if scientists know how CR impacts the microbiome. Thanks!
I know you're are probably busy, but you need to do more vids Rhonda.
@FoundMyFitness
8 жыл бұрын
+somfplease You're right! Full on holiday mode right now, but I have a bunch coming soon.
@somfplease
8 жыл бұрын
FoundMyFitness Cool, thanks. Have a good xmas + new years!
@donkeydonk96
8 жыл бұрын
+FoundMyFitness What is your view on Goitrogens and Oxalates in raw kale and spinach?
@chainr1ng
8 жыл бұрын
+somfplease Become a supporter, like me, on Patreon. She's doing God's work. We should pay for content that enriches our lives so that we can continue to receive this great stuff. I just upped my pledge tenfold last week. Just a suggestion. Cheers.
@barry0044
8 жыл бұрын
these two gate keepers support vaccination... they destroy the microbiome.. thats their role ;)
Excellent interview. Thanks Rhonda.
thanks dr rhonda, you're freaking awesome!
Excited to read your book! One question: how do undiagnosed food intolerances/sensitivities/allergies affect the microbiome? As we learn more about the microbiomes of children & their mothers, I'm cautiously hopeful to see positive societal effects (requiring employers to provide even a few weeks maternity/paternity leave; decrease or elimination of the stigma of public breastfeeding, etc.).
Thank you so much for addressing the benefits of breast feeding! I have done research on increasing breast feeding among a maternal population in under-served population using contingency contracting. While we all know that "knowing" (giving people information and expecting them to 'rationally' make optimal choices) doesn't necessary drive people's motivation to adapt a behavior (such as breast feeding in a community that doesn't necessarily make breast feeding easy) - I still think that giving people the strong scientific reasons for choosing breast feeding over formula feeding is VERY important in changing meta-contingencies in our communities. LOVE your work!!
In June I had dental work done and the endo gave me a powerful post-op antibiotic. I’ve never reacted so badly to this particular kind. My colon was producing so much mucus and gas that I couldn’t pass gas anymore. It even led to bleeding. I went to my doctor and all blood tests show absolutely nothing. I’m slowly recovering but it’s two steps forward one step back.
@garybankston9319
2 жыл бұрын
I have unfortunately had problems passing gas. Finally it hit me that I excessive inflammation of my colon. I took 20,000 units of vitamin D3 for 3 days and I was fine. But I could have recovered in the same period of time without the D3. If it happens again I will go to the D3 again. I think my inflammation was from food poisoning.
Great job by the guest doctors.
I am a Cheese maker. I make an Edam using nothing but Probiotics and ground Juniper Berry. It is very good and I made it to deliver the microbial all the way through the trip. I reset my gut bacteria awhile back due to inflammatory problems. So I had a candida problem and a low count of beneficial bacteria. So I started with a 7 day fast, then as a first meal I ate complex fiber and probiotics to break the fast. This has been followed up cyclically with shorter fasts. I am on a very low sugar diet, very low carbohydrate, very high complex carbohydrates from veggies, some low sugar fruit, high probiotic cheeses , fish protein. Results were losing 45#, increasing my good bacteria count 20+ bugs over the average gut biome. and basically getting my life back.
Dont have a large intestine.....i wonder if i knew all this 25 years ago if i would ever have needed surgery. Sucks but at least i have no chance of colon cancer...thats always a nice pro
Awesome interview and questions! Thank you!
Great episode learned alot. Time to boost the gut biome
Great Job Dr.Rhonda you are one of the best interviewer which I saw in any media ...smart questions,simply great Job !thank you for your passion and will to spread the knowledge.I personally appreciate it very much!!
Thank you! Very appreciated. I'm 95% vegan and have stretches where I cave into cakes, sugars. I'm moderately overweight and would love to find a way to kill the cravings for sugar, once I've indulged. I'm big on daily intake of kale, spinach, onions, carrots, fruit a little.
Great video ! All about the importance of what kind of food we eat, and this starts already with the breastfeeding of the babies !!
@OswaldDigestiveClinic
3 жыл бұрын
If you found this informative, you may also want to know that soil-based probiotics are a product that some people are interested in. Natural alternatives to taking this type of supplement include: going outside and walking in the soil, buying fresh, local, and organic produce from farmers that you trust that has been freshly picked, and taking a tbsp of fermented foods several times per day to get trillions of bacteria!!
Please consider having on Kiran Krishnan (cofounder and chief scientist at Microbiome Labs). Kiran seems convinced that 'leaky gut' plays a significant causal role in many if not most diseases. I'd be curious to hear Ronda and Kiran discuss microbiology as well as health and disease in general.
Very informative! Thank you so much, found you via Robb Wolf. I'm a fan!
Having diverticulitis in the past. Had surgery back in Nov. 2019. But, of late I have been having a lot of problems with my stomach. A lot of diarrhea and discomfort. As you know I have not been able to see my Physician because of the Covid 19. I know I don't have the best diet being a truck driver and single. But, I just retired at the end of May and intend on doing something about that. Anyway, I was hoping you could point me in the right direction. Keep well, Rick
great interview
@terrytari1891
4 жыл бұрын
She great at it. She knows how to handle the media!
starting to think bacteria evolved human beings to be better hosts for more bacteria.... ie, they build us to create a home. We exist for their survival.
@Ausare911
8 жыл бұрын
Agreed!
@aaronmarshall1212
8 жыл бұрын
Fascinating
@ronyan1
7 жыл бұрын
That was some long term planning.
@brandon2762
7 жыл бұрын
We obviously have coevolved interactions (think of the highly specified and complex interactions bacteria have with other lifeforms) where evolution of an animal triggers an evolution in bacteria and vice versa. However, evolutionary processes are tied to DNA/RNA carriers so their main "objective" (which evolution doesn't actually have, it's just a result) is to spread their own genetic material. I guess all I'm trying to say is that we evolved each other. Every DNA/RNA carrier exists for their own survival. Hypothetically, if a human cell evolved into a cancer-like cell in such a way that it could spread its genetic material more effectively by killing other human cells, then it would.
@tewtravelers9586
7 жыл бұрын
I think humans evolved for weed to be smoked
Very great therapeutic information please explain anything of the .Corona Virus
Great interview. Thank you.
@OswaldDigestiveClinic
3 жыл бұрын
If you liked this video, you may also want to know that there are advantages and disadvantages to taking soil-based probiotics. For example, soil-based probiotics are more spore-forming. The spore creates a protective barrier so that the microorganisms are more likely to travel through the stomach without being destroyed by stomach acid. So they are more likely to attach in the gut, and be effective. On the other hand, this can be a negative if the microorganism causes an infection, because it is then more resistant to an antibiotic that may be needed to treat the infection!
Wonderful conversation Exploring in depth great privilege to listen to thems
Thanks for sharing this! to add to this, sometimes people wonder if probiotic supplements are safe. Some factors to consider for safety are: if you trust the company you're buying from including where they are sourcing the probiotic from and their manufacturing methods, the existing research on the specific strain that you are buying, the strength of your immune system (immunocompromised people should avoid probiotics), and the other ingredients in the probiotic besides the probiotic (Ex: if you're lactose sensitive and the probiotic contains lactose, it may make your symptoms worse).
@lbabyk
2 жыл бұрын
Can you help me understand why? immune-comprised has to avoid probiotics?
I loved this interview
When Erica says the immune system over reacts (10:20 +) by eating the lining of our gut when complex carbohydrates aren't available, would that be the cause of leaky gut and Diverticulitis?
Fuck me this is fascinating. Our bodies are basically tubes of bacteria. Mind blown.
Thank you so much for sharing! Hugs & sunshine ☀ N
Thank you so much Dr Rhonda this was an excellent interview well done. Have you covered the survival ratios of the probiotic from mouth, intake to colon, when recovering from a antibiotic treatment. Also what are the better ways or are there any intake systems to ensure that the probiotics get to the lower intestinal tract system. I have a question on Men suffering from candidia bacterial overgrowth. And its relation to the gut biome.
What's with the number countdown at 28:54?
Okay, so is VSL 3 good to take or not?!? It's not approved by USP but it is kept at a cold temp unlike many others.
Any thoughts that some of health supplements we take like turmeric and ginger, coco, grapeseed extract work not from their direct absorption into blood stream but rather as prebiotics cultivating certain strains of bacteria in our guts that are antiinflammatory. This would explain why some people may not respond to a supplement if a necessary bacterial strain that is absent. I know that tumeric's anti inflammatory mechanism is dependent upon the presence of interluken10 (IL10 ) I have also ready studies that IL 10 is stimulated by the bacteria reuteri, casei and paracasei. So taking a probiotic containing these strains are along with turmeric is the way to go.
Thank you for making this video :)
If gut bacteria in the colon require fiber, and they don't get it, then problems occur. So what negative consequences happen during a long term water fast?
@ShevaFC
5 жыл бұрын
exactly what was talked about in the video. the bacteria will eat into the gut wall for food, causing leaky gut
@aaronmaxim
5 жыл бұрын
....prob skip that unless you really wanna feel like garbage. Eat.....
@stevejoshua9536
5 жыл бұрын
The exact cause of leaky gut is still a mystery, but extended water fasting is extremely beneficial for 97% of the general population, and resets the body back into balance. My question is, if fiber intake is anti-inflammatory, then how do they explain the anti-inflammatory effects of the Carnivore Diet, which would seem to me to be lacking in fiber ?
@bluewaters3100
4 жыл бұрын
@@ShevaFC You have a pretty thick wall of mucous that the bacteria can eat that does not go into your actual gut causing it to become leaky.
The amount of blinking in this video made me start manually blinking
would like to see the evidence that gut bacteria feed on gut lining when fiber is low. two different food groups for carb feeding bacteria.
The vast majority of anti biotic use is via Farm animals... Also available OTC in many Asian countries...
This is awesome stuff!
These videos are amazing!!!
@OswaldDigestiveClinic
3 жыл бұрын
If you liked this video, you may also want to know that soil-based probiotics come from the soil, whereas other probiotics come from other places!
Emulsifiers are problematic - so does that include Lecithin? I'm supplementing with that for choline and because I thought it was good in general.
Protein consumption and exercise has been shown to increase microbial diversity as was studied with our national rugby team! See Gut 2014 Published online first 09/06/2014 doi:10.1136/gutjnl-2013-306541 “Exercise and associated dietary extremes impact on gut microbial diversity”
32:14 Interesting you said that you found after taking a supplement - other probiotics (not in the tablet) entered your gut. It could be explained by how some probiotics "produce substances that are harmful to pathogenic bacteria, such as lactic acid and hydrogen peroxide". This could make room for others to enter more easily. I would like to know if the new positive bacteria remained after stopping taking the supplements.
Thank you for the videos!
I can't find anything from the Sonnenburg's since 2017. What is the status of their research? Is there progress being made regarding how to get the extinct bacteria to start showing up again?
@eugeniebreida1583
2 жыл бұрын
I’m curious as well!
great presentation! thanks!
I don't think Rhonda is totally correct here. It's true that chronic inflammation drives damage in aging but its also probably true that we wouldn't have chronic inflammatory changes if there wasn't some sort of damage going on. I will say that if we had a way of knocking out monocytes and macrophages selectively that would be a really great benefit (probably).
@aaronsilver-pell411
4 жыл бұрын
but is inflammation the PRIMARY driver of aging (the inducer of the damage). I don't think it is.
Love you so much Rhonda!
I think it's great that you talk about all this stuff in generality but I think you need to be more specific on the foods like the lectins in the glutens like tomatoes sauce and tomato juice is good for you but the tomato seeds and the tomato skin is not good for you likewise some tomatoes are even better than other tomatoes
Asthma allergies... My childhood story. I wish my parents knew this shit.
Serious question: Could one gain the beneficial gut bacteria of a healthy person such as Dr. Rhonda Patrick by performing analingus on her? Have any clinical studies been conducted?
@Doriesep6622
4 жыл бұрын
You have no sex life. Go pay your mom some rent.
He mentions "emulsifiers" also breaking down the mucin. Which ones his he referring to?
@myjaminone
8 жыл бұрын
+inculoasorata yes thats interesting. even my natural whey powder has emulsifiers. also whats considered as an emulsifier overdose?
@lisamcguire7778
4 жыл бұрын
If it states " Emulsifiers" on the label, DO NOT EAT IT. Just understand this couple told you a vital truth, an important piece of information that could save your health.
@SutekhDaSteemroller
4 жыл бұрын
Don't drink almond or soy milk
I have heard that blending food destroys the fibre and renders it useless as food for the gut microbiota, is that true? Does anyone know if Rhonda talks about this somewhere?
@mightymochi6320
6 жыл бұрын
According to what I've read / been exposed to, juicing is not a smart health trend. Juicing stuff like fruit for example removes the fiber, which aids in a normal digestive process. Without it, you're just getting an unmitigated straight shot of sugar that'll spike your blood levels and cause inflammation, etc. I don't know if I'd say it's useless for the gut microbiota, since you are going to get the nutrients from the food that you are juicing. The big problem is the unmitigated shot of sugar you're getting. And it's so easy to overdo it when you're throwing a bunch of shit into a blender. It's best to just eat food normally.
@armadillotoe
4 жыл бұрын
I am sure it is fine.
Since i started playing with antibiotics i no longer feel like my self, no energy no motivation, sometimes depreseed. I yook 2 weeks of antibiotics for h.pylori eradication. Metronidazole,ppi, tetracycline and bismuth. Had some dental cativities too. After few months i still am feeling like i can’t do anything to improve my self estem. I need to get back to education but i just do not have energy for it...
@lisamcguire7778
4 жыл бұрын
You're on the right path coming here to learn. Upgrade your DIET. ALSO, check out Marisa Peer on KZread. She's very helpful for examining and addressing personal issues.
The doctors suggest more fiber (from a variety of sources) which include fermentible fibers/carbohydrates. Is that the same type of fiber/carbs that a low-FODMAPS diet suggests to avoid?
Thank you Dr Patrick for your work. You’re channel serves as inspiration for me as I am about to start college as a molecular and cell biology major. I have a question on gluten. I have read a lot about how it is very inflammatory and has lead to the degradation of the epithelial cell wall in the gut leading to leaky gut syndrome (right?). Considering gluten is found in wheat, is it something I should avoud despite being a whole grain with dietary fiber? Thanks again
Variety of foods is important.
I’m elderly and have a continuous bladder infection and have just finished my 6th antibiotic in 4 months and still not rid of it, I’m desperate not to have another antibiotic but don’t know what to do as I realise I have destroyed all the good bacteria in my intestines and still not healed of my infection.
FoundMyFitness - Wow, this is SUCH a good interview, one that stimulates many questions not covered here. I'd love to know this couple and continue the discussion. Note that as broad a discussion of the microbiota this is, it doesn't have time to cover the subject of probiotic fungi, mostly yeast. Thank you, Dr. Rhonda Patrick.
@higherresolution4490
6 жыл бұрын
NOTE: The gut barrier discussed here is more than the mucosal lining of the lumen (collection of gut epithelial cells). Equally, it is the short-lived enterocytes (brush boarder cells) connected by tight junctions that, when injured or compromised by a toxic diet, form lacunae (gaps) leading to the leaky gut syndrome.
@higherresolution4490
6 жыл бұрын
At MINUTE 27:40, Dr. Sonnenburg mentions that antibiotics are wonderful drugs if used correctly. However, having worked in a mitochondrial genetics lab, he may not realize that antibiotics aimed at bacterial membrane proteins and RNA also attack our mitochondria (formally a blue-green spirochete endosymbiont) with remnants of its bacterial genome and double membrane still present. We and other labs were recruited to see if it was possible to make an antibiotic without this side-effect.
@higherresolution4490
6 жыл бұрын
The strict definition of commensal flora, or in this case, bacteria is that they do no harm to the host, but unlike symbiotic flora, offer nothing. The problem with commensal flora (bacteria and yeast) is that if your system is run down and operating at suboptimal capcity, commensal flora often become pathogenic. C. albicans yeast and many types of E. coli bateria are good examples.
What if you have too much of the wrong bacteria? Wont feeding them in the colon be detrimental? In other words, how do you feed the good guys whilst starving the bad ones?
@chroniclerofthe70s
8 жыл бұрын
+inculoasorata That is an excellent question. Yes, bacteria in the gastrointestinal tract ( known as enterobacteria ) can cause injury to the lining of the g.i. tract. There are dozens of different species of bacteria, some of these can break down proteins and carbohydrates and produce nitrogen compounds, acids, and fats that can induce cancer. Salmonella species are found in the g.i. tract of many kinds of mammals and can cause ulcers in the g.i. tract. Tuberculosis species are the prime suspects of causing ulcers in the g.i. tract of humans ( crohns disease ) and in cattle. I suggest not overeating on simple sugars ( sucrose, fructose ) and eat a well balanced diet which includes fibers. Bacteria break down and convert simple sugars quickly and easily producing many gases and acids which can harm the lining of the g.i. tract. Bacteria do not easily break down fibers and thus fibers tends to keep gut bacterial growth in check.
@jaym9846
7 жыл бұрын
During the course of evolution, plants have developed pharmaceuticals to control bacteria. Just include a variety of minimally-processed, whole, plant-based foods.
@sarahmarzouq1935
6 жыл бұрын
inculoasorata choose the right foods for each.
@fuzuzafitness8354
6 жыл бұрын
inculoasorata eat less sugary junk and processed food and more veggies and greens in variety along with fruits
@COINsimp2024
6 жыл бұрын
You can use the right pre-biotics. ModVellum Clinical (my company) just launched a product called ModBiome which does exactly that. The product has clinically proven prebiotics that can affect the ratios. Bacteria is never fully bad just in the wrong amounts.
I've read quite a bit on gut health and most gut-healing diets recommend cutting out starchy and leguminous vegetables and most fruits. Is this because, once you have starved your healthy gut bacteria, those fibers are not digestible and will, therefore, cause bloating? I am just curious whether one could receive those fibers only from non-starchy, non-leguminous vegetables in order to re-introduce sufficient bacteria for digesting fruit and starchy vegetables? Or are those gut-healing diets just incorrect? Would appreciate any feedback.
@ale189251
5 жыл бұрын
And also if this is correct. A gut healing diet should be a low fat vegan diet. With like tubers, beans. Im confused lol.
@melikey3758
5 жыл бұрын
Anri Wentzel I don’t think it matters as much about the starches or legumes(unless you have a gluten sensitivity/allergy/etc). Think about it, people have been eating bread and beans forever, but the obesity and chronic disease crisis started only 30 years ago. I think it matters more if you don’t eat processed food, but only Whole Foods, and Fermenting/probiotics will also help.
So ive been binging the microbiome vids and ive realised noone has talked about gas and what is considered healthy and normal. When is gas too much and a sign that maybe you should cut that particular food from your diet or is all gas a sign that your microbiome is at work and you just got bare it...
@armadillotoe
4 жыл бұрын
As the microbiome which feeds off the particular fiber you eat, increase, I believe the gas will decrease. I could be wrong.
Alot is making fckin sense now!.......
If dietary fiber is a big reason for reduction of autoimmune response, and inflammation, then why are so many people experiencing reduction in autoimmune response and inflammation while on the carnivore diet? Is it because meat requires a longer digestion and therefore doesn’t starve the microbes in your colon like glucose based food do?
Love this podcast! But what im wondering is if a high quality probiotic can "feed" these microbes.?
@orangemoonglows2692
8 жыл бұрын
+Jade Sea prebiotics feed probiotics. probiotics are beneficial microbes. basically, you need to load up on fruits, vegetables, grains and legumes. read their book the good gut. prebiotics is fiber basically. that's what you have to focus on.
When one smoothies their fruits and vegetables, does this somehow adversely affect he fibre component? perhaps cutting up the fibre too much so there's no roughage.
Do you know about spore probiotics? In particular 'MegaSporeBiotic' from Microbiome Labs? I've heard Kiran Krishnan speak about the microbiome and how their probiotic interacts with it and he sounds quite convincing and he has some studies backing up his claims and more studies are continually being planned. I'd love to hear you two go into the mechanistic details discussing physiological pathways and molecular mechanisms.
Thanks
I sometimes wonder with Rhondas videos who is interviewing who?
How do vaccines affect our microbiome?
absolutely fascinating!
. My focus is on Achoo Aero-Enviro Allergies. Beginning in the Womb, Allergy is a Lifetime Cumulative / Progressive / Chronic Disease. Today’s Allergy = Tomorrow’s Allergic Rhinitis > Allergic Asthma > AutoImmune. It would be interesting to see what % of AutoImmune Suffers also Suffer from Enviro Allergies. My feeling is that 24 / 7/ 365 / a LifeTime of Hyper Sensitized Allergy Status is a “Foundation” on which AutoImmune Diseases emerge. Neutralize the Foundation and EveryThing that is Building from It, Fall. Stephen @ GOOy CHEWy
Fruit is a simple carbohydrate. Fructose. Simple to process Complex carbs are polysaccharides, starches. Complex because they are a combination of sugars.
@rednarok
4 жыл бұрын
Fruit is not a simple carb because it brings fiber along with it. Fruit juice in the other hand is terribly simple carbs comparing to coka cola even.
So would it be fine giving a baby VSL#3? Start off life like a champ.