How MRI Works - Part 2 - The Spin Echo

Ғылым және технология

How MRI works - Part 2: The Spin Echo.
Part 1 - NMR Basics: • How MRI Works - Part 1...
Part 3 - Fourier Theory and kSpace: • How MRI Works - Part 3...
Part 4 - The Gradient Echo Sequence: • How MRI Works - Part 4...
Slides can be purchased here:
/ powerpoint-slides-how-...
0:00 - Intro
0:26 - What is Boltzmann Magnetization?
4:17 - Recap of the NMR Experiment and NMR Signal
7:04 - Clarification of Spin vs Ensemble Moments
8:42 - NMR Experiment Transmission (Tx) and Reception (Rx)
11:10 - Performing the NMR Experiment
13:07 - Two spins in different fields and T2*
16:09 - Larmor Distributions, Stacked spin dephasing and T2
19:23 - Transverse Magnetization M(t) and Frequency Distributions f(w)
25:00 - Larmor Distributions, Stacked spin dephasing and T2
27:43 - T2 vs T2* decay in Tissue
30:03 - Recap and Intro to the Spin Echo
30:49 - The Spin Echo Experiment
33:18 - Explanation of the Spin Echo
35:04 - Echo phase and Echo Math
37:14 - Conclusion and Exercises
38:11 - Outro
Drinking game: Take a drink every time I say "dramatically/substantially/drastically/ reduced".

Пікірлер: 116

  • @thepirl903
    @thepirl9033 жыл бұрын

    Error Correction: 13:30 - The units of gyromagnetic ratio are rad/s/T (I forgot a 'per second' in my slide). Note that the 'MHz/T' unit is fine though.

  • @yyyyyyyyyz
    @yyyyyyyyyz3 жыл бұрын

    2 years later! I wasn't sure if part 2 would ever be published, but am happy to see it. Thanks for the great explanations!

  • @AseveraTv

    @AseveraTv

    3 жыл бұрын

    the time has come *happy tears*

  • @BryanQ95
    @BryanQ953 жыл бұрын

    This absolute mad man delivers almost 3 years later. Excellent videos btw, I'm excited for part 3!

  • @Aphelia.
    @Aphelia.3 жыл бұрын

    Can't wait for the part 3 coming in 2023

  • @manuelbonet

    @manuelbonet

    Жыл бұрын

    No need to wait that much! It was published 12 days ago

  • @pennypaul4997
    @pennypaul49972 жыл бұрын

    I started watching this series with zero knowledge of MRI physics. A year later during my MSc, man delivers. Great timing and great delivery! The animations are topnotch and the humour makes it even more fun. 🙌🏾

  • @finanzasypersonas5060
    @finanzasypersonas50603 жыл бұрын

    This is absolutely awesome. I just started my Ph.D. working with NMR and this information is absolutely worthy. Congratulations!!!

  • @alop3933
    @alop39332 жыл бұрын

    The Best, by far, the Best MRI video explanation series on internet. Excellent content.

  • @andrewgerry7687
    @andrewgerry7687 Жыл бұрын

    I feel like these are the only super in-depth and or mathematical based videos worth watching on this platform for MRI physics. What is your background or expertise in? are you a diagnostic medical physicist?

  • @nigeriantvc
    @nigeriantvc3 жыл бұрын

    This is the Best video lecture i ever watch on KZread. I have been waiting for this 2nd part for more than a year. Thanks so much for this amazing great job Sir 💪🙌👏

  • @ThirdHare

    @ThirdHare

    3 жыл бұрын

    So true! Animations used are fantastic.

  • @HiteshPatel-yb7jc
    @HiteshPatel-yb7jc3 жыл бұрын

    Like others I was waiting expectantly for Part II, and now .... for Part III and IV! Aside from the information, we can also admire the production. Thank you.

  • @jupa7166
    @jupa71663 жыл бұрын

    Subscribed "just in case" - yay! Second part of the best mri explanation on youtube! Thank you!

  • @jacobharris3002
    @jacobharris30028 ай бұрын

    33:20 This finally made the relationship between the Free Induction Decay, the spin echo and graphs I have from my NMR lab come together for me. Thank you so much for this. I've been struggling to grasp this concept for a while.

  • @ruenjou
    @ruenjou Жыл бұрын

    I'm glad I found this video yesterday; no need to wait for 2 years to see them all.

  • @lexinwonderland5741
    @lexinwonderland5741 Жыл бұрын

    I am so glad you're making this series-- please, please, PLEASE keep it up!!! I found you thru SoME2, but my primary focus is neuro-focused biochemistry, and getting a math based explanation to how the imaging works is so wonderful!! you've made me significantly more interested in radiology from your three videos alone!

  • @riteshdas5769
    @riteshdas57692 жыл бұрын

    I can already tell the Fourier video is gonna be a banger.

  • @AlexM-pu6kb
    @AlexM-pu6kb2 жыл бұрын

    A fantastic video series that I wish to see continued! Great explanations and even greater animations that truly make a difference to understand. Most of the videos out here are hard to follow due to lacking animations. This helps immensely and I cannot thank you enough and appreciate the work you put in this. Please do continue, I cannot wait for the next parts! Also, do you - or anyone else here - has a book recommendation for MR-Physics? Looking for one that also explains different sequences like TOF, FLAIR, CEST etc. Thanks!

  • @user-bb6lw9eg9e
    @user-bb6lw9eg9e25 күн бұрын

    Thank you very much for this series!

  • @kerryl565
    @kerryl565 Жыл бұрын

    Man, I cannot wait for Part 3 - I want to smart right now, haha! I appreciate how time consuming these videos must be to make with all the graphics and animations, and its because of the graphics and animations that make your explanation of the concepts so much more understandable than textbooks or traditional lectures - thank you!

  • @camicanu
    @camicanu2 жыл бұрын

    Can't wait for next part coming! This lectures are pure gold

  • @91726
    @917262 жыл бұрын

    This is hands down the BEST explanation of the spin echo

  • @anielaadamus9544
    @anielaadamus95442 жыл бұрын

    Thank you so much for coming back with Part 2! As someone with zero medical knowledge and minimal physics background I'm finding these super clear and easy to understand! I needed a clear review of NMR principles for borehole logging applications and you videos definitely deliver :) Don't think I'll live long enough to see Part 3 and 4 though... a bit jealous of people who find your videos in the future when all parts are out haha

  • @plusleo1083
    @plusleo10832 жыл бұрын

    Brilliant lecture. Full respect for your hard work to deliver knowledge to us.

  • @abdallahalhalabi1275
    @abdallahalhalabi12752 жыл бұрын

    Best MRI explanation videos, please continue.

  • @ric1703te
    @ric1703te Жыл бұрын

    A very comprehensive approach since part I. Feeling thankful for finding the videos - I admire the effort put in them: the graphics and formulas used and explained in an understandable manner. Waiting expectantly for part III.

  • @steves8309
    @steves8309 Жыл бұрын

    Awesome explanations and great ASMR voice. The second time I watched it, I was asleep in minutes. Great videos!

  • @pigtowndanzee
    @pigtowndanzee2 жыл бұрын

    Thank you so much for these videos! I cannot even comprehend how much work goes into making them so I really appreciate it. As we all anxiously await the next videos, could you provide a couple of your favorite textbooks/papers/websites/whatever that you reference on this topic?

  • @SkatinBoy244
    @SkatinBoy2443 жыл бұрын

    Hell YES! I've been waiting for this video since the first one, astoundingly good explanations. Thank you!!

  • @TheGutiserra
    @TheGutiserra2 жыл бұрын

    😍😍😍 I thought we would never get a second episode. This is top tier material.

  • @RD2564
    @RD25643 жыл бұрын

    Part 2 after 2 2/3 years, woo-hoo!!! Great vids, thanks for your efforts.

  • @gutterball10
    @gutterball10 Жыл бұрын

    Excellent follow-up video.

  • @rukminiroyy
    @rukminiroyy2 жыл бұрын

    Thank you for this; so happy i finally get what's happening aha please post more, you're doing a lot of us such a service !!!

  • @ThirdHare
    @ThirdHare3 жыл бұрын

    Buzzing! I've been waiting two years for this video! Thank you!

  • @haroldfong8758
    @haroldfong8758 Жыл бұрын

    Another great video about MRI

  • @juang.8799
    @juang.87993 жыл бұрын

    Great explanation !! You made this very understandable. Thanks!

  • @mattiterzi
    @mattiterzi Жыл бұрын

    Most beautiful presentation of mri foundations. Huge congratulations

  • @AudioAtmos
    @AudioAtmos2 жыл бұрын

    Thanks for doing this! It is the most informative and understandable presentation I have seen.👍

  • @daviddoudouable
    @daviddoudouable Жыл бұрын

    Your videos part 1 and 2 are fantastic!!!!!!!!!! Jumping now to the next with delight!!!!!!!

  • @felipemonteiro5877
    @felipemonteiro58773 жыл бұрын

    Yes!!! I've been waiting sooo long for this! Thank you very much for your efforts!

  • @ziyanyang9777
    @ziyanyang9777 Жыл бұрын

    This series on visual representation is just phenomenal. I wonder how long it take to produce all those 3D animations.

  • @FreelanceMartin
    @FreelanceMartin2 жыл бұрын

    You are good. Thanks. Hope you make part 3!

  • @tinynudges
    @tinynudges2 жыл бұрын

    This video is wonderful! I would pay for the next two!

  • @brynjarkarlsson8646
    @brynjarkarlsson86463 жыл бұрын

    Great stuff, thanks so much, worth the wait. Will recommend to my students.

  • @harryhht8821
    @harryhht8821 Жыл бұрын

    Awesome visualization

  • @frzarlink
    @frzarlink Жыл бұрын

    These videos are awesome! Thank you.

  • @deepukurian9757
    @deepukurian97572 жыл бұрын

    Great explanations.. Waiting for the next videos

  • @walrus4248
    @walrus42482 жыл бұрын

    The animation and quality of the narration voice are really excellent!

  • @guidoenriquelambertucci3542
    @guidoenriquelambertucci35423 жыл бұрын

    YEEEES! I was so waiting for this. THANK YOU

  • @gjhufken
    @gjhufken3 жыл бұрын

    Thanks for the valuable follow-up of part 1 !;-)

  • @Frofelfel
    @Frofelfel3 жыл бұрын

    Wow i cant believe it you finally made it man ! Great

  • @user-dt1be8pb1m
    @user-dt1be8pb1m8 ай бұрын

    The best video about RM and SE that I have ever seen. Please, more. Are there more than three videos?

  • @KriptixxEdit
    @KriptixxEdit2 жыл бұрын

    Can't wait for the next videos to come!

  • @shivanisingh7090
    @shivanisingh70903 жыл бұрын

    Great explanation!!

  • @adammendez3632
    @adammendez36323 жыл бұрын

    WOW YOU CAME BACK 2yrs of waiting HAHAHA cheers

  • @Xraystocks
    @Xraystocks2 жыл бұрын

    Great work and understanding 👍

  • @212035720
    @2120357202 жыл бұрын

    Outstanding Video.

  • @ceci7637
    @ceci7637 Жыл бұрын

    Thank you very much 🙏🏻

  • @prashantkumar9167
    @prashantkumar91672 жыл бұрын

    You did a very noble job sir... Love ❤you

  • @scottdow5171
    @scottdow51712 жыл бұрын

    I eagerly await your Fourier video!

  • @engrhscabrera
    @engrhscabrera3 жыл бұрын

    Waited for this video like I waited for Infinity War and Endgame.

  • @roflawlmao123
    @roflawlmao123 Жыл бұрын

    Fantastic!

  • @wesslesyt3304
    @wesslesyt3304 Жыл бұрын

    im starting MRI school soon I LOVE THIS STUFF. I await for part 3

  • @Thepiecat
    @Thepiecat2 жыл бұрын

    When are you getting a Patreon? Top notch quality, thank you for teaching us!

  • @Mkoivuka
    @Mkoivuka Жыл бұрын

    Next do a short video on the visualization of MRI images in surgical navigation !

  • @federico9472
    @federico94722 жыл бұрын

    A video on Diffusion MRI would be great!

  • @Gigaswing
    @Gigaswing Жыл бұрын

    tnx for a great job...may there be a part 3 ?...would be great to see one :)

  • @xinyanxiang4574
    @xinyanxiang4574 Жыл бұрын

    What a nice video!

  • @user-gr4rr5zj5e
    @user-gr4rr5zj5e Жыл бұрын

    That's just awesome for a beginner like me!!

  • @kindnessasgreatasthesea1158
    @kindnessasgreatasthesea11583 жыл бұрын

    THANK YOU!

  • @natashamol2961
    @natashamol29613 жыл бұрын

    Amazing work!!! Best intro to MRI ve seen so far. Thank you so much 😍😍 Will be waiting for continuation 🙏🏻

  • @luc7478
    @luc74782 жыл бұрын

    Thank you a lot

  • @MarinatedPasta
    @MarinatedPasta Жыл бұрын

    More plz ❤️

  • @RayJacobsenJr
    @RayJacobsenJr3 жыл бұрын

    Thank you Thank you! Thank you!!

  • @gabrielmorales2366
    @gabrielmorales23662 жыл бұрын

    Great video! What tool are you using to create the animations? Manim?

  • @affanhassan
    @affanhassan Жыл бұрын

    Part 3 please!

  • @dilshanwelagedara376
    @dilshanwelagedara3766 ай бұрын

    Thanks very much 🤩

  • @1denvco
    @1denvco2 жыл бұрын

    Hello. Terrific content, it's been very helpful. I'm studying to take the MRI registry in Sept 2022 and was wondering what resources you are using or planning to use for your gradients, imaging, and pulse sequences video? Just in case it is not uploaded so I can study from there...if that is alright. I greatly appreciate the work you put into your content! TY

  • @soleparadise4822

    @soleparadise4822

    Жыл бұрын

    How’d it go!? I am studying now and want to take the registry by May 2023!

  • @vadimtitko7087
    @vadimtitko70873 жыл бұрын

    Nice video. Reminds me of 3Blue1Brown.

  • @noahoogeweg9562
    @noahoogeweg9562 Жыл бұрын

    How did you make these animations? They are great!

  • @cmlon
    @cmlon2 жыл бұрын

    you are great!

  • @InquilineKea
    @InquilineKea2 жыл бұрын

    HOLY SHIT THIS IS SO GOODC

  • @amianifineug1353
    @amianifineug13532 жыл бұрын

    thank you a lot! Please I want to use Matlab please do you have an idea which model I use in order to write a code in Matlab to study MRI (thank you)

  • @axelknutt5065
    @axelknutt5065 Жыл бұрын

    I had an MRI two days ago … I wondered why it was so cold in there. Now I know!

  • @mferraro89
    @mferraro89 Жыл бұрын

    Do you have any textbook recommendations? I'd like to dive very deep into this and build myself an MRI machine

  • @831zlakin
    @831zlakin2 жыл бұрын

    For T1 tissue signals, does the pulse of RF, like in the case ofT2 tissue signals with the Spin-Echoes, produce more available signal for imaging? Basically, I am trying to figure out if there is anything analogous to Spin-Echo but for T1 signals. Thank you for your help!

  • @thepirl903

    @thepirl903

    2 жыл бұрын

    Interesting question. There's no T1 'echo' of sorts like can be done with T2, but you can preserve magnetization from excitation to excitation by taking advantage of 'leftover' transverse magnetization between pulses. There are sequences that produce 'stimulated' echoes (distinct from spin echoes) which exhibit this effect. I think a magnetization preserving sequence such as steady-state free precession (ssfp/bssfp) or a look-locker (e.g., molli) might be close to what you're looking for, but I'm not sure. Hope this helps

  • @831zlakin

    @831zlakin

    2 жыл бұрын

    @@thepirl903 This does help, thank you!

  • @amartinezsilberstein
    @amartinezsilberstein2 жыл бұрын

    Part 3 🥺

  • @daneilpatro2776
    @daneilpatro27763 ай бұрын

    hey thankyou

  • @mahealom6076
    @mahealom6076 Жыл бұрын

    Please, give the GRE sequence physics's

  • @matheusdv3920
    @matheusdv39203 жыл бұрын

    thePIRL: "you shoul watch the first video or you migh get lost in this one" me: beeing already lost by the first part of tge first video haha just kidding, but most of the concepts are challenging to grasp

  • @nottyboi1349
    @nottyboi13492 жыл бұрын

    You should collaborate with Grant Sanderson!

  • @Thepiecat

    @Thepiecat

    2 жыл бұрын

    Pretty sure he's using the python package that 3blue1brown uses

  • @mertyaroglu4964
    @mertyaroglu496411 күн бұрын

    Did the quantum mechanical NMR video ever came out? Does anyone know?

  • @peterphan8991
    @peterphan89912 жыл бұрын

    "deliver B1 perpendicular to B0 about the which our magnetization will precess" I cannot imagine where B1 placed in . Does it mean the B1 can be placed in any place just need parallel to the transverse, right?

  • @stargazer7644
    @stargazer7644 Жыл бұрын

    My only question is, who learns MRI technology at this level of detail? What course teaches it and who takes it? Is this simply for engineers who design this kind of equipment, or do the people who operate it or interpret the results also learn it?

  • @paperbag76
    @paperbag76 Жыл бұрын

    I watched Part 1 and it was great. However, I am stuck at 5:24 of Part 2, when the equation S = Mw first appears (Signal = Boltzmann Magnetization times precession frequency). This seems to come out of nowhere, without a derivation from any of the previous (S) Signal equations from Part 1.

  • @sachinrajpandey5242
    @sachinrajpandey5242 Жыл бұрын

    I didn't see the video on gradients, imaging and pulse sequences, if anyone found that then please send me the link. Thank you.

  • @alexlo7708
    @alexlo7708 Жыл бұрын

    Looks like the old system TV PAL sync. vector scheme.

  • @Blueyzachary
    @Blueyzachary6 ай бұрын

    Wait so how did I understand more than half of this when I failed AP calc?

  • @kasrapirahesh6938
    @kasrapirahesh69382 жыл бұрын

    Hi, I just don't get how the Radio Frequency signal generated by the RF coil causes the protons to spin in a perpendicular angle to the B0. Can someone explain this a bit (I don't mean the formula, just how does it happen)? Thanks for the great video by the way!

  • @gabrielmorales2366

    @gabrielmorales2366

    2 жыл бұрын

    Short answer: the RF coils are placed in such a way that the magnetic field that they generate (B1) is orthogonal to B0. When the coils are transmitting, the protons will tend to align their precession along the B1 axis. When the coils stop transmitting, the protons will relax again and align along the axis of the main B0 field.

  • @msgreymatter4061

    @msgreymatter4061

    2 жыл бұрын

    In my (very limited) understanding: It's the magnetic field (creted by the protons' precession) which is orthogonal to B0 (i.e. in xy-plane) - not the individual precession itself. Spins are still either up or down. The 90° are not a literal description of the precession movement, but describe the accumulation of phase-coherent precession movement across multiple spins/protons. So there's a lot of 1H-nuclei (= 1 proton each) throughout the body --> 60-70% of us is made of water... But not all the hydrogen protons start to align to B0, only somewhat under 0.1% of them. And some spin in parallel direction to B0, while others spin anti-prallel to it. But there are slightly more spinning parallel, so we get a signal for the longitudinal magnetization from their cumulated vectors. Now the RF coil hits at the larmor frequency for hydrogen. This will cause *some* of those few parallel-precessing spins to change their direction to anti-parallel. Hence, the longitudinal signal is lost. But because the RF-pulse also brings them into phase coherence, the perfectly aligned precession movement across all of those spins now adds up and creates a measurable signal. And this signal is orthogonal to z, because they precede in the xy-plane (both parallel and anti-parallel spins). But they really have to be phase-coherent (i.e., always at the same position), otherwise the T2-signal gets lost again (like it does once the RF-pulse is switched off).

  • @msgreymatter4061

    @msgreymatter4061

    2 жыл бұрын

    Corrections most welcome. I am nothing close to an expert on any of this.

  • @arpita0608
    @arpita0608 Жыл бұрын

    Can I get the slide?

  • @36_azzamadnan28
    @36_azzamadnan283 жыл бұрын

    2 years after waiting :)

  • @OspreyII
    @OspreyII3 жыл бұрын

    3 years later

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