How does Narcan (naloxone) Work?

How does Narcan (naloxone) Work? Pharmacology for Nurses
Narcan (naloxone) is an opioid antagonist which means it will move any opioids currently sitting in a receptor site - out, and Narcan will take its place to prevent opioids from binding. The opioid that was originally sitting in the receptor site functioned to change the cell activity. Opioid receptor sites can be found in the brain, nervous system, and intestines. The ones we are concerned with here are the ones in the brainstem as when opioids connect to those receptor sites, the drive to breathe decreases.
You may come upon a patient who is breathing very slow or not breathing at all. If Narcan is available, you can administer it. It will not harm someone who has never taken Narcan and it may potentially save a life.
Narcan is given every 2 to 3 minutes if there is no response and in your kit, there will be three doses. If the patient does respond to the first dose, they may wake up agitated because all their pain is back. They should stay awake for 2o to 60 minutes before the Narcan is depleted, leaving the opioid receptor sites free for the opioids that are still circulating to bind. As opioids have a longer half-life, many doses of Narcan are usually required.
As opioids have a longer half-life, we often need to use Narcan more than one time on the same patient.
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Пікірлер: 83

  • @toyalambeth366
    @toyalambeth366 Жыл бұрын

    Living in Las Vegas I think we need to blast your video on the billboards. Everyone needs to have narcan on hand to help out with the opioid pandemic. Thank you!

  • @MeaThreattoDemocracy

    @MeaThreattoDemocracy

    11 ай бұрын

    I'm inclined to believe with Narcan, the cure is worse than the disease.

  • @Cyclegladiator
    @Cyclegladiator2 жыл бұрын

    When you mention that all of the pain a patient previously had will come back immediately, you should also remind that the patient will be in full-blown opiate withdrawal which is most likely the reason for hostility

  • @lilcxtofficial1264
    @lilcxtofficial12642 жыл бұрын

    You’re the kind of non-judgemental person I feel like would incubate an incredible conversation. Thank you for the video, it was an enjoyable lesson 🙏

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    😊

  • @HollieMM
    @HollieMM2 жыл бұрын

    When I was in grade 10-12 there was an opioid pandemic. I graduated in 1999, I'm 40 now. And thankfully it never happened to me but it is still happening. I recently picked up a kit from the pharmacy. I hope I never have to use it. Thank you for the video!!

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    I hope you never need it, but having it is awesome in case you do

  • @jamesclinesr2511

    @jamesclinesr2511

    Жыл бұрын

    It wasn’t half as bad then as it is now. I am 43 I graduated in 98 I don’t remember no opioid pandemic down at all media people did it, but it wasn’t. They weren’t dropping dead like they are now not even close.

  • @BigBadBalrog
    @BigBadBalrog3 ай бұрын

    What a beautiful video. Thank you for dispelling doubts and questions about a highly stigmatized topic.

  • @NurseMinder

    @NurseMinder

    3 ай бұрын

    Thank you for your comment, and time

  • @pixie1768
    @pixie17683 жыл бұрын

    No idea how I got to this video but glad I did. Thanks for sharing the info. You are a great trainer too!

  • @pirate0bloodyskull
    @pirate0bloodyskull2 жыл бұрын

    This video was so informative. It answered every question I had about naloxone.

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Yeah!!!! Stay safe

  • @daveamoroso
    @daveamoroso Жыл бұрын

    Very Good Explanation.. Good Job...

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Thank you

  • @Istandal0ne1
    @Istandal0ne1 Жыл бұрын

    This video is priceless! Thank you Nurse!

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    You are welcome 🙏

  • @tuskiomisham
    @tuskiomisham7 ай бұрын

    3 years on this is the only youtube video I can find on narcan's functional mechanishm. Thank you!

  • @NurseMinder

    @NurseMinder

    7 ай бұрын

    You are welcome :)

  • @AdamGrier
    @AdamGrier Жыл бұрын

    You diving on top of the patient is badass

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Hahaha

  • @mannystarz1644
    @mannystarz1644 Жыл бұрын

    I’m usually never into this type of stuff but this was so interesting to me. The biology behind it and the history is really cool. Hopefully I don’t have to use this information in the future 😂

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    It is pretty cool! Thank you for sharing

  • @crod8387
    @crod8387 Жыл бұрын

    I'm learning about hypertension so that I can get off the meds. I find your videos very informative. Thank you!

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Great! Keep your healthcare team involved.

  • @lloydpenney6689
    @lloydpenney66892 жыл бұрын

    I got a Naloxone kit because I go to festivals and other events during the summer and I wanted one handy. (my brother-in-law lost a nephew to a fentanyl OD.) I'm glad I watched your video now I understand a lot more on the drugs work and the responses to expect. Thanks for doing this. Y Penney - in Ontario

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Happy to help :)

  • @westfield90
    @westfield90 Жыл бұрын

    Thank you. So well explained.

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    💕

  • @janana6138
    @janana61383 жыл бұрын

    Very informative, I’ve always been curious and this in depth explanation has really explained things. I thought your personal experience was interesting as well. 👍

  • @NurseMinder

    @NurseMinder

    3 жыл бұрын

    Thanks!

  • @leejganderson7827
    @leejganderson78272 жыл бұрын

    Thank you for this more simplicity way to understand Narcan Peace *Have a Safe* *Happy Holiday Season* 👍😉🍀👍😉🍀

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Appreciate the feedback. Happy holiday season to you as well

  • @roland.j.ruttledge
    @roland.j.ruttledge2 жыл бұрын

    great info, many thanks UK

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Glad it was helpful!

  • @robbymann5839
    @robbymann58392 жыл бұрын

    Cool Thank you

  • @Nan-59
    @Nan-592 жыл бұрын

    That's a fabulous kit!! In the states, our kits come with only 2 doses, and none of the extras! Gloves, breathing device, etc!

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Oh wow! I always find it fascinating how different places do things

  • @ValFromMontreal

    @ValFromMontreal

    Жыл бұрын

    @@NurseMinder In Quebec too, only two doses. Thanks for the video!

  • @lbabytutorials4852
    @lbabytutorials48522 жыл бұрын

    I overdosed on heroin one time and they put Narcan up my nose. I swear to God when I woke up it was like I had so much energy. I didn’t know why everyone was around me staring at me. It was so crazy, I want to know why Narcan put me into rapid withdrawal. My skin started crawling, I was sweating, it was hell. So I want to know what’s in Narcan that makes someone that overdose is going to withdraw

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Thanks for sharing your experience. When Narcan is used, it will look for any narcotic and remove the narcotic from a receptor site. And then Narcan will block that site so the medication cannot find. It is as if you have not taken any medication once Narcan is on board. Problem is Narcan only last for a short time, and then as it dissolves the medication will again connect into the receptor. So it can be a up-and-down ride

  • @brendanfogel4573
    @brendanfogel45733 жыл бұрын

    It’s crazy what scientist have done

  • @TheFlatEarthChannelcom
    @TheFlatEarthChannelcom2 жыл бұрын

    Saved my life last night

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Happy to hear 💕

  • @PinkJoy143
    @PinkJoy143 Жыл бұрын

    Wonderful job, thank you so much. This may be a silly question....is it possible to give it to bring yourself back? Like as you feel yourself going down. Is that unheard of? You addressed a terrifying, shameful, and secretive subject un~biased with ease in quirky

  • @PinkJoy143

    @PinkJoy143

    Жыл бұрын

    with ease in a quirky and thorough delivery.

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Yes you can give it to yourself. Its one of the benefits of having the kit

  • @MikiBreki
    @MikiBreki3 жыл бұрын

    Cool stuff

  • @maliksutton6634
    @maliksutton66343 жыл бұрын

    Hi Mrs Tammy, I enjoyed watching you explaining Narcan also known as Nalcoxone and how they can be a pain reliever for Opioid. I found this topic interesting because I am a Human Services major at college and have taken some courses which explains addiction, pain relief, aging, substance abuse and so on. Can Narcan make a person addicted just as if it was a prescription or another drug. Also, I checked out your mask fog prevention video an hour ago and found it helpful to learn about how to reduce foggy glasses. I left behind a link to a product that may help because I purchase mine's last Monday and it has made a difference in wearing a mask to where I can breathe better and less suffocation. I also have some other tips on how to reduce foggy glasses. 1 Use good anti-fog product. 2 Place glasses on top of the mask. 3 Fit mask to your face. 4 Use medical tape to create a seal. 5 Absorb the moisture by inserting tissue inside the mask.

  • @NurseMinder

    @NurseMinder

    3 жыл бұрын

    Thanks Malik. Narcan does not create an addiction. Narcan has no effect on someone who has no opioids on board.

  • @maliksutton6634

    @maliksutton6634

    3 жыл бұрын

    Thanks for the clarification Mrs Tammy, I really appreciate it.

  • @orangeguy8859
    @orangeguy88592 жыл бұрын

    I’ve always wanted to know what other things can narcan take care of

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Opiods

  • @kenbrownfield6584
    @kenbrownfield6584 Жыл бұрын

    Can you do a vid on how to use the nasal spray please

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    I don’t have access to the nasal spray for demo. If I get a kit, then I will

  • @kenbrownfield6584

    @kenbrownfield6584

    Жыл бұрын

    @@NurseMinder Thanks

  • @williamkeech9359
    @williamkeech93593 жыл бұрын

    Would it be legal for me, a citizen of North Carolina, to carry Narcan in case of an emergency where I have to use it to save someone?

  • @NurseMinder

    @NurseMinder

    3 жыл бұрын

    It is handed out here free no questions asked

  • @Nan-59

    @Nan-59

    2 жыл бұрын

    Yes! Please carry Narcan! You could save someone's life! I've been carrying for years.

  • @Earthboundmisfit1
    @Earthboundmisfit12 жыл бұрын

    Can you explain accutane

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Did you find your answers? I have not researched accutane yet

  • @mwoods4608
    @mwoods46082 жыл бұрын

    my son needed 4 doses last night

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Yes it is commonly needed more than one time. I hope all is ok

  • @spongebobstiddies2960
    @spongebobstiddies29602 жыл бұрын

    of course the first time you needed to use narcan was in downtown winnipeg😂

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Familiar with the area are you 😁

  • @raebennett1174
    @raebennett1174 Жыл бұрын

    When someone is overdosing there no way in hell you got the time to take a wipe and clean the vile

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    I get it. It feels like a stressful situation and that every second counts, but you have time. Research shows we can go up to 4 minutes without oxygen before damage begins

  • @JB-xl3ix
    @JB-xl3ix2 жыл бұрын

    me at 2am

  • @RedLoveShow
    @RedLoveShow3 жыл бұрын

    if any one need Opiod to forget pain. It's much better to smoke weed than opiod.

  • @kimberlycararillo2475
    @kimberlycararillo2475 Жыл бұрын

    Narcan will bring the dead back to life

  • @NurseMinder

    @NurseMinder

    Жыл бұрын

    Not quite - but it feels like it

  • @kimberlycararillo2475

    @kimberlycararillo2475

    Жыл бұрын

    @@NurseMinder I've seen that stuff work like and off and on switch

  • @r4k00n5
    @r4k00n52 жыл бұрын

    Working on a song. Woke up with shit in my nose Smell was stuffy and i needed to blow People hold me down tell me its okay This is gonna be an interesting day Ambulance rushes me away Make small talk the nurse, name was Trey Worked in biomedical Told me my weed had fentanyl Arive at the hopital, feelin blue Wondering if my suspicions are true That my dealer is A massive fucking piece of shit They wheel me to my new apartment Nurse reaches in the glove conpartment Touches my face and checks my eyes Holy fuck I want fo die Parents arive, blank look on their face Tell me I'm the family disgrace

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    Sounds like you have had an experience

  • @jb1611
    @jb16112 жыл бұрын

    u bad i’m ngl

  • @NurseMinder

    @NurseMinder

    2 жыл бұрын

    ?

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