I can not believe that one man can have such substantial knowledge in not only one field, but many fields. Furthermore, you have excellent communication; clarity of speech and simplicity in process and explanation that makes your teachings flawless.

This guy literally has a video for everything, hopefully going on to do my paramedic science degree next year. Thank you for all of the help along the way

@ProfShibe

2 жыл бұрын

Yeah it's crazy how many videos he has stuff on. Used to watch him involuntarily for school years ago and here I am watching about insulin and endocrinology out of personal interest lmao

how does this guy know literally everything

@indevious9659

3 жыл бұрын

^^^^ these guys are scammers beware

@alvalosfranklin1785

3 жыл бұрын

After... several...years...of... suffering..I am.. finally...free....from.. diabetes! All.. thanks...to..dr..ehisz...on.. KZread"

@tonytone1378

3 жыл бұрын

He uses Khan Academy to learn topics.

Thank you for explaining this so clearly. I have diabetes type 1, so I know about that part. But I had totally misunderstood the type 2 diabetes. Thank you!

Excellent explanation of the two types of Diabetes. Thank you! I'm passing on to our homeschool group in an effort to help those who don't understand what my Type 1 daughter has. LOVE your videos, my son is learning his math skills using nothing but. He's into Physics currently and in the 8th grade. We are so glad you took on this enormous task to help others!

Simple straight to the point. Good refresher. Thanks

I always feel so smart after watching Sal's videos.

I came on youtube (guiltily procrastinating) and your videos saved that! They're exellent, thank you kindly.

I love all of your videos. You make everything so easy to understand.

You need to revise this video about insulin receptors and diabetes. I would draw a small artery in red, small vein in blue, and a met arteriole that connects the two. Then show a capillary bed that branches off of the met arteriole. Insulin binds with an insulin receptor which causes the cell to signal the release of glucose transporters from cytoplasmic vesicles. Glucose transporter type 4 in skeletal muscle is the most numerous. The GLUTs and not the Insulin receptor allow glucose.

Sal, you are the man! Thanks to you and and your team, from NYC.

Although I'm not a biology student,I do remember taking these in high school.I have to say that the way you explained it is brilliant and very clear.Thank you so much for helping spread free education for all.MAY ALLAH BLESS YOU

Very good! Thank you.

You make everything so easy to understand. I survived A&P I and II thanks to you :]

I have a test tomorrow on this and the video helps so much!!

That explains high blood sugar : overpopulation of glucose molecules.

I've looked at 10 videos so far that helped me to understand this NONE. Thank you so much. Your voice & diagrams are so easy to follow.

@venusplomeris1342

8 жыл бұрын

Effective natural remedies, prevention, lifestyle changes and diet for diabetes *Diabetescurediets .com*

@angelabeney6675

5 жыл бұрын

I agree ! very clever ! Thank you :)

@alvalosfranklin1785

3 жыл бұрын

After... several...years...of... suffering..I am.. finally...free....from.. diabetes! All.. thanks...to..dr..ehisz...on.. KZread'

Explained in a very simple way.. Thank you

I'm never gonna forget they way You explained it. Keep it Up !! :) Bless you

You explained explained it so good in just three minutes

Explained it very good. Thank you so much for all of your videos:)

Don't forget that the brain, red blood cells and exercising muscle don't need insulin to internalize glucose. Therefore in patients with Type 2 DM, exercise can be a very effective took to manage blood glucose levels. Of course it isn't perfect, but if the name of the game is to control blood glucose (so that it doesn't damage end-arteries, for instance), then every little bit helps. Great video though, and nicely illustrates the difference between to two type of diabetes mellitus. Note also that there is a "diabetes insipidus" that has nothing really to do with blood glucose.

so grateful to be able to learn. God blessings to all the staff

@jhovsuico8533

6 жыл бұрын

Thanks for the video content! Apologies for chiming in, I am interested in your opinion. Have you heard the talk about - Patlarny Diabetes Ruins Principle (Have a quick look on google cant remember the place now)? It is a good one off guide for destroying diabetes minus the hard work. Ive heard some amazing things about it and my GF at very last got cool success with it.

Easy to understand thanks

THAT WAS SO SIMPLE... why the fuck was it rocket science when my professor gave a lecture on this?

@lilypauser

6 жыл бұрын

LOL

man, this man is amazing...

You are awesome ; thank you so much!!!

Love all of your videos...

thank you.

Thanks for this video, I use the Freestyle Libre sensor with Ambrosia NightRider to check the glucose levels on the phone and sometimes I use watch to monitor the levels.

@shreyarastogi7303

3 жыл бұрын

one of my friend suggested me for Ambrosia device, now I am using it for last 6 months which always track me the glucose, insulin, exercise on one platform and I am able to extend the life of my sensor with the help of Blucon for another 14 days.

EXCELLENT ~ First time ever that I have really undersTOOD diabetes

i really liked this video!

Nice video, I love my Libre 14days and Blucon cgm together, both helps me to manage my blood glucose. My Blucon give me alarms on my and my patners phone when I’m high or low so that’s nice.

Sal, you should have your own series, like Carl Sagan's COSMOS or something. It would be awesome!

Thank you !! .. I can finally understand Diabetes =)

What did you use to make your video? It's really awesome.

Thank you

Thanku so so much.. Your explanation is mind blowing....

Such a good explanation

excellent ...job

You're a lifesaver💥💥👏🏻

your voice is legend man

Thanks for the video, I am using Freestyle Libre sensor with Ambrosia Blucon and check the glucose values on my phone directly without scanning the sensor and reader. Also, the app gives me updates with voice alerts when my glucose values go down.

@lisaandrew4421

3 жыл бұрын

My son is using Nightrider, which always helps us to get alarms, readings update. Life changing product.

Very well presented to this dummy about diabetes since I don’t have it but wanted to learn about it. It amazes me how many diabetics are still overweight!

It seems to me that T2 diabetes is an issue with the cells getting glucose(sugar) into the cell, it's not a problem with sugar, or a problem with insulin. Is that correct?

IN KHAN WE TRUST!!!

This dude teaching me better than most of my college professors

what about intramyocellular lipid?

Thanks man, now i now wich type i have. Too little sugar makes you weak and too mutch may start destroing your veins.

I AM USING GLIMP -G2 TO CONTROL SUGAR, IT IS RECOMMENDED OR NOT, IS THERE IS ANY SIDE EFFECTS OF USING THE ABOVE MEDICINE?

And therefore you are one of the people I'm glad to be on the planet with.

Karp, Gerald, Cell and Molecular Biology, 4th ed, pages 648 through 652 in chapter 15 on cell signalling and transduction. Martini, Fredric, Fundamentals of Anatomy & Physiology, 7th ed. page 715 metarterioles and capillary beds. Looking for source to explain the folding of RBCs as they pass through capillaries

I've come to the conclusion that you pretty much learn whatever material you're going to do a tutorial on in one day for the next day or you know pretty much everything about everything.

It's actually not at the level of the receptors but at the downstream signaling pathways that the defect in insulin sensitivity in type 2 diabetes is located... Although patients with inherited mutations in the insulin receptor gene that lead to reduced levels of the insulin receptor or with defects in the insulin receptor do exists (Rabson-Mendenhall syndrome and Donohue syndrome).

I was hoping you were gonna explain glucagon too :(

It is important to revise the video to show the capillary beds which provide nutrients and take away waste products from many cells. The disease process of diabetes and the damage to capillaries is very important to understand. With diabetes and high levels of sugar in the blood stream, sugar non enzymatically ( not in the body's recipe book ) binds to the inside of the blood vessels. Mature red blood cells have lost most of their organelles but must fold to pass through the capillary beds

I'm just curious about one thing - what are the insulin receptors made of? Are they proteins?

You might also mention that the pancreas is really two organs. Exocrine ( digestive enzymes released into the duodenum ) and endocrine ( Islet of Langerhans cells Alpha, Beta, Delta, PP, Epsilon that secrete glucagon, insulin, amylin 2, somatostatin, etc ). The Beta Langerhan cells contain GLUT 2 that sense the level of sugar and lead to the release of insulin.

No mention of adipose?

Ketone bodies can fuel muscle cells as well.

ah ok thanks :)

Would like to know why cells would resist insulin.

I LOVE YOU.. u saved my grades lol

So excess sugar leads to the insulin receptors being desensitised?

Kahn academy has some mind opening videos. This simple video unlocked alot of question and my previous facts i had in my head, but couldn't just fit tm into the right picture. This video elegant and simple. And the funny thing is - i went to a tripp to neightbouring country and i bought cheap candy- and the only thing i have eaten today- and he says, you donbt want to much sugar in ur blood because its dammageing ^^. well ill get myshelf some real food really quick.

can you please tell me what glycogen is!!??

We’ll summarized🤗

Is fasting sugar 110 normal?

You may need to consult a 1. cell biology text 2. biochemistry review text. Younger students will probably see a side note in their anatomy text that discusses diabetes. Diabetes and obesity are a major cause of health problems in the United States. It would be very beneficial for young people to understand a better model of the disease. I often use an analogy of tree branches and leaves to explain capillary beds and also lung bifurcations for COPD.

Wow

Thank you Dr Igudia for being the most trusted doctor among all, your professionalism was on a high standard, thank you for coming to help me out with my diabetes

What does C6H12O6 break down into? Does O6 stand for six oxygens? Thank you

@kambriamcdonald3520

9 жыл бұрын

6 Carbon 12 Hydrogen 6 Oxygen

My grades improved when I started watching these videos! I am where I had been, a top student!

Can you explain how sugar causes damage to the body?

@mygoldentruth

9 жыл бұрын

It increases vascular osmolarity, for example. This promotes osmotic flow (of water) from the tissues to the veins/arteries. Of course, this would end up lowering vascular osmolarity but increasing tissues', leading to a equilibrium. The thing is that this equilibrium is leaving tissue cells dehydrated. That's not cool. There may be more reasons, of course; but that's the one I can think about right now.

@seth5899

4 жыл бұрын

Glucose molecules are “big and clunky.” When they get pushed through vessels and capillaries that are 1 cell thick, the molecules tend to shred the really small vessels, causing diabetic neuropathy. This is also linked to damage in the feet, hands, eyes, gums, etc. That’s how it was explained to me, anyway, so take it with a grain of salt. ¯\_(ツ)_/¯

@3aDaNy21 AMEEN!

Factors that cause type2diabetes? Too much fat and/or sugar intake right?

thank for sharing the information.mere massi ko diabetes ki problem thi unke friend ne unk planet ayurveda ke ayurvedic treatment krwaya to abb wo bilkul thik h .unka treatment really working.

So, in what case do you NOT need insulin? What happens if you only eat proteins and fats in a meal, can the body metabolise this without insulin?

@seth5899

4 жыл бұрын

John Doe No, this scenario can extend the life of someone with diabetes, but no one can live without carbohydrates or at least a small amount of background insulin.

@danvitale1825

2 жыл бұрын

Glucagon to transfer stored glucose to cells.

Nicolae Paulescu was a Romanian scientist who discovered the substance that temporarily reduce blood sugar levels,called today insulin. Paulescu called this substance Pancreine and realized its important role in 1916, when he injected the substance into the jugular of diabetic dogs and observed that their blood sugar returned temporarily to normal levels.But in the midst of his findings, Paulescu was called to join the armed forces of Romania.

This is the complete opposite of what macrophage is saying. What macrophage is saying, Glucose enters the cells "to be stored" and not to be used as energy. When the body needs energy, cells release the stored energy back into the bloodstream.

Reducing the amount of carbohydrates you eat can reduce the amount of insulin your body will produce, effectively helping the body become more sensitized to insulin again. It's a much better solution than to inject more insulin to your body, which would just make your body more greedy for it in the long run, but of course, this would mean a high-fat, protein and low carb diet. It'd make us have less glucose in our body overall, especially since all carbs turn to glucose starting in the mouth.

So, if i were to be an athlete. And i wanted to enhance the energy of my cells for recovery purposes, then i could take insulin.

@seth5899

4 жыл бұрын

SerratusBrah Lol be careful if you do this. You could become insulin dependent and take injections for the rest of your life, essentially giving yourself T1D. I know a guy who tried to bulk using insulin and he has diabetes now.

It's actually not the 'great majority' of cells: brain, smooth muscle (stomach, colon etc), kidney, spleen, all DON'T need insulin to absorb glucose. Skeletal muscle is the only one that needs insulin (it uses GLUT4 channels)

Thanks you Dr Igudia on KZread for all you do in my life and my family. I went for a test today after taking the medication i ordered from Dr Igudia and I tested Type 2 diabetes’s negative. Thanks doctor I will keep letting the world know about your good work sir

But insulin is also storing fat, so for type 2 diabetes, it would be better to cut down on carbs, then the person with diabetes wouldn't need insulin shots because he/she don't have high sugar levels in the blood stream. (PS: sorry if I've gotten the words wrong or the wrong grammar, English is not my native language)

@panagiotisatmatzidis9972

10 жыл бұрын

Cells need a specific amount of glucose to to gain ATP (energy currency of the cells). If they don't get that, their metabolic properties and respiration (oxygen) becomes inefficient causing ischemia, which can cause a heart attack (angine pectoris). So if you don't wanna risk a heart attack better take insulin. If you have hypertension ACE inhibitors might help with both conditions (diabetes and hypertension).

@Spyflugan123

10 жыл бұрын

The body can make the glucose it needs. Also, I don't have diabetes so I don't need to take insulin shots

@panagiotisatmatzidis9972

10 жыл бұрын

Spyflugan123 I wasn't talking about you. Also the phrases "the body can make enough insulin" and "type 2 diabetes" do not play well together.

Thank you Dr Osas for curing me from diabetes am forever grateful sir

I certainly now KNAN hahaha....

Times used to be very Challenging, I had the worst days of my life living with type 2 Diabetes, I appreciate you so much Dr Igudia, You have restored me my life that was lost already . Thank you so much for curing me of my diabetes with your natural Herbs

CAC Shilajit is available in the form of Shilajit Satva. It is a potent Immunity Booster and acts as an antioxidant, possesses anti-inflammatory properties. It has a tremendous effect on Male Harmones, Anaemia, Alziehmers disease, improves brain functions, Fatigueness, various Tumours and Cysts like PCOD in females. Due to its anti-inflammatory properties it works on inflamed lymph nodes as well. It balances blood sugar, increases absorption of nutrients, helps in detoxification, helps in reducing mood swings. Recommended Dosage: As directed by physician.

💃🏽

Words aren’t enough for me to show how I grateful I am for helping me to get rid of my type 2 Diabetes Dr Igudia.

i want to study organic chemistry but its so dam compllicated

Thank you for never letting me down doc. being recommended to doctor Igudia on KZread has being a great blessing to my family his cure for diabetes is a genuine one thanks for your good deed toward humanity

khanye west

टाइप टू डायबिटीज खत्म हो जाती है सौ प्रतिशत बैरायट्रीक सर्जरी से रामबाण उपाय है बैरायट्रीक सर्जरी

I PLEDGE ALLEGIANCE.... TO THE UNITED STATES OF KHAMERICA, AND TO THE REPUBLIC ON WHICH IT STANDS. ONE NATION.... UNDER KHAN.... INDIVISIBLE.... WITH LIBERTY AND JUSTICE FOR ALL!!!!

Much too simplified.

Screw this

DIABEETUS

You need to revise this video about insulin receptors and diabetes. I would draw a small artery in red, small vein in blue, and a met arteriole that connects the two. Then show a capillary bed that branches off of the met arteriole. Insulin binds with an insulin receptor which causes the cell to signal the release of glucose transporters from cytoplasmic vesicles. Glucose transporter type 4 in skeletal muscle is the most numerous. The GLUTs and not the Insulin receptor allow glucose.