Genetic mutation | gene mutation
Genetic mutation in humans explained. This lecture explains about gene mutation and chromosomal mutation in animals. gene mutations and genetic mutations are dangerous and the effect is horrifying.
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A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most humans. Mutations variety in dimension; they are able to have an impact on wherever from a single DNA building block (base pair) to a huge segment of a chromosome that involves more than one genes.
Gene mutations can be classified in two most important approaches:
Hereditary mutations are inherited from a mother or father and are present for the period of a individual’s lifestyles in practically each mobile within the body. These mutations are also referred to as germline mutations due to the fact they're present within the mum or dad’s egg or sperm cells, which might be also called germ cells. When an egg and a sperm mobilephone unite, the resulting fertilized egg telephone receives DNA from both mum and dad. If this DNA has a mutation, the youngster that grows from the fertilized egg may have the mutation in every of his or her cells.
Acquired (or somatic) mutations arise at some time during a character’s lifestyles and are present handiest in specified cells, not in each telephone within the physique. These changes can also be induced by using environmental explanations corresponding to ultraviolet radiation from the solar, or can occur if a mistake is made as DNA copies itself for the period of telephone division. Acquired mutations in somatic cells (cells rather then sperm and egg cells) can't be passed on to the next iteration.
Genetic changes that are described as de novo (new) mutations can be either hereditary or somatic. In some cases, the mutation occurs in a man or woman’s egg or sperm mobile but isn't present in any of the character’s other cells. In other instances, the mutation happens in the fertilized egg quickly after the egg and sperm cells unite. (it's commonly unimaginable to tell exactly when a de novo mutation happened.) because the fertilized egg divides, each and every resulting phone within the developing embryo could have the mutation. De novo mutations could provide an explanation for genetic issues wherein an affected child has a mutation in each mobilephone in the physique however the mum and dad don't, and there is not any loved ones historical past of the sickness.
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Thank you best teacher ever this is final year of my university and I used 95 percentage of your videos during my exams all of them was very helpful I do appreciate you I will always support you by sharing or writing comments and other ways keep going for our next generation!!!
@shomusbiologyofficial
6 жыл бұрын
Thank you very much for appreciating my efforts. It's a proud moment
@raafaya3232
3 жыл бұрын
@@shomusbiologyofficial best 8 mins 46 seconds on this topic
@dr.mahaboobaliprofessor7220
Жыл бұрын
@@shomusbiologyofficial Thanks sir Greetings
Today I know much about MUTATION . I am 9 years old and I am in 4th class But , I love to know new things in the nature and much more . THANK YOU 😁
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share
@priya-qq3pk
9 күн бұрын
Keep up the spark You'll go very far in life
No one could explain this complicated biological observations than you. Salute
Surely Allah will bless u !! And serve u with beautiful life..
@shomusbiologyofficial
4 жыл бұрын
You're welcome
@ShyamLal-vk3hm
4 жыл бұрын
R u muslim, coz u r using hindu name...
@minireji5763
2 жыл бұрын
Good explanation, Sir 🙏
I've been writing notes for this topic for 3 hours and I didn't understand it.. and I just watched your videos and I understood it. Thank you !!!
@shomusbiologyofficial
4 жыл бұрын
Glad to hear that you're getting benefit from my lectures
Sir, Why mutation is helpful in secondary metabolite so plz tell me the reason
Can you please tell me how does the ph effect on mutations.
hi shomu. I have a question about the point additions that cause frame shifts. so when you added that A to the sequence, does the complementary DNA strand also get an addition (i.e. an additional T)? or is it just the one strand that gets mutated? thanks!
Thank you for the information. You are true. No need to see other videos if you see this video. You can learn all about the genetic mutation from this video.
@shomusbiologyofficial
4 жыл бұрын
Glad to hear that you're getting benefit from my lectures
explanation technique is fantastic......
You have completed lot of topics from our syllabus...most helpful channel ever ❤️👍🏻keep it up sir...😍
@shomusbiologyofficial
2 жыл бұрын
Thank you so much for appreciating my efforts
It will b very helpful if u will make a video about mutation affecting the regulation of gene expression.vry much need of this vdo
Is dna is most susceptible to uv radiation?
Help me what is one copy of a double mutation mean, I need help understanding
The term mutation refers to a permanent change in the genetic material or nucleotide sequence of a gene giving rise to a new genetic trait or genotype
Sir one question ...why microbial mutation is necessary for formentation process
Best video! Keep on making these helpful videos!
@shomusbiologyofficial
3 жыл бұрын
Thank you. Glad you liked my lectures
Hello Sir Can You please upload a video explaining the mechanism of UV rays on DNA. Tell me which of the UV wavelength is suitable to cause mutation in bacterial DNA. What is the Difference in absorption using 260 and 365 nm?
@istiakrana8969
2 жыл бұрын
Cutie 💞
THANKS!! THIS REALLY HELPED ME!
@shomusbiologyofficial
5 жыл бұрын
You're welcome
can you please explain the cause of mutation or precisely mechanism of mutation? Thank you in advance...
thank you very helpful
Sir pranam... I Have a question that what is the difference between Gene mutation&chromosomal mutation?
May God bless you dear sir..... 🤩🤩💗💗👍👍👍🙏🙏🙏🙏🙏🙏🙏🙏
I have one question since 12th: Why insertion or deletion of multiple of 3 bp is not a frame shift mutation? Insertion may be any where, I may be b/w two codons or b/w bp of one codon.
is there any video regarding crossing over in detail?
Thank You Sir, this video was very helpful.
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Can there be any mutation without foreign agent or factor?
Sir u said at 2:08 " That many mutations are there where phenotypic change is not reflected by gene change " , sir is this statement same as to that " many mutations are there where gene change is not reflected by the phenotypic change " or u wanted to say second latter statement ????
@letscreatesomething6969
4 жыл бұрын
Here your sir is not replying 🤣🤣🤣🤣
Hi everyone ! I know this may be sort of off topic but I am a 27 yo female and I have Essential Thrombocythemia with the “SF1” gene mutation/myeloid malignancy (48.5% proliferation). Is there anyone here that is familiar with SF1 and can possibly explain ? I am finding very little information on the mutation. I was diagnosed with a platelet count of 1.4 million and I am intolerant of oral platelet reducing drugs and interferon has negatively affected my thyroid function. I am seeking some answers. If any of you may have some insight, please feel free to respond ! ✊🏽
Allah bless you. You'll reach a good teacher. ☺
@shomusbiologyofficial
4 жыл бұрын
Thank you. Glad you liked my lectures
Sir I understood all but I dont know what is amplification
sir I m not able to.understand...what is CLB method and what is attached X..method??..plzzz sir help me to understand this via ur lecture as soon as possible .. bcz my exams are coming 😞
@sn3ho_
5 жыл бұрын
🙂🙂😚😚 exam is coll
thank you sir..
Thank you so much sir
Please make video on variant of uncertain significance
Good lectureing power without hesitation
@shomusbiologyofficial
4 жыл бұрын
Thank you
This video was great. It helped me a lot
@shomusbiologyofficial
4 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
Nice sir what is row metireal
In the quest to understand the basis of infertility in humans, researchers have identified a mutation in a gene associated with chiasmata. This protein normally acts to promote homologous recombination. Why might a defect in homologous recombination have consequences for fertility?
Sir muj cow genetic inproomant Karna hai to genetic silecsan kin kin bas par karu?????
Thank you sir for your valuable video
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Bohut Aala bro.👌👌
Thank you so much for solving my problem
@shomusbiologyofficial
5 жыл бұрын
You're welcome
@dna_
4 жыл бұрын
The same I wanted to present....
My best teacher ever love u sir
@shomusbiologyofficial
5 жыл бұрын
Thank you. Glad you liked my lectures
Thank you very much you were right after seeing your video I don't have to see other video it helped me very and once again thank you
Tnk u anna❤ur way of explaining is v easy to understand anna❤ from TN❤
@shomusbiologyofficial
4 жыл бұрын
Glad to hear that you're getting benefit from my lectures
What's the difference between gene and genetic? ?
very helpfuu
I m fan of his teaching.
@shomusbiologyofficial
3 жыл бұрын
Thank you
How the repair dna by fruits & veggi
Thank u so much sir.... Your videos are very helpful to me... 🙏😍
@shomusbiologyofficial
2 жыл бұрын
Thank you so much for appreciating my efforts
Your videos are the best
@shomusbiologyofficial
2 жыл бұрын
Thank you
hey buddy, great video and very helpful infos! Btw, can you make videos about the genetics of flowerhorn fish?
@letscreatesomething6969
4 жыл бұрын
You from ?
@nilstancabag695
4 жыл бұрын
@@letscreatesomething6969 singapore
Thank you so much for the lecture 👏👏
@shomusbiologyofficial
2 жыл бұрын
You're welcome
Can we say this the generic mutation is major role player in evolution of human race or kind.?
nice video with easy understanding
@gayatrisaxena1782
7 жыл бұрын
vfghv
@AtifAli-in7xh
7 жыл бұрын
yes u right
@AtifAli-in7xh
7 жыл бұрын
u right
i am very helpful to this video.Thank you s o much sir
@shomusbiologyofficial
3 жыл бұрын
You're welcome
Sir upload complete video on lungs in deep knowledge plzz🙏🙏🙏🙏🙏
iam in 9th and i have half yearly exams from tomorrow and first exam is biology thanks for helping with your videos sir
@shomusbiologyofficial
Жыл бұрын
All the best
Thank you so much sir. Your videos are very helpful to me because of these videos I got a good persentage in graduation even if it was in distance mode.🙏
@shomusbiologyofficial
5 ай бұрын
All the best
If we know that a gene will cause cancer in feature by mutation, why cant we eliminate the gene and , if yes how to eliminate it
Nice
Does the mutation occur in every cell simultaneously or does it occur in one cell and we call it a mutation?
@shomusbiologyofficial
2 жыл бұрын
It start with one cell then it spreads to multiple cells
Coming back here to drop news! I passed my cytogenetics, thanks to you for making it easier to comprehend the concepts! I'm still around your channel for my microbiology hehe.
@shomusbiologyofficial
3 жыл бұрын
Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures. Please subscribe and share
In case of humans how to mutate a gene for own benifit , like if some genes are responsible for memory power we can mutate the gene and creat a intelligent person like einstein
Please explain the mechanism of transition and transversion mutation
@shomusbiologyofficial
4 жыл бұрын
Okay in a different video
@adarshsharma5412
4 жыл бұрын
Ok sir
Thank you sir 💯 you always save us
@shomusbiologyofficial
6 ай бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
Good explained ❤❤
@shomusbiologyofficial
3 ай бұрын
Thank you
hi shomu ji,my question is that can a mutation be reversed like from CTG TO CTA and again CTG from mutations to same nucleotide will it work properly or is it impossible.please answer.
@ajaygoyanka
6 жыл бұрын
farman khan yes! Its called a reverse mutation.
Thank you Sir ji
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Sir please make video of this topic in hindi i.e Mutation and it's type
@shomusbiologyofficial
4 жыл бұрын
Okay
Can you answer these?... I need your help Refer to the DNA base sequence below: CCG-ATA-GGC-CAA •Which of these strands explains the kind of tRNA used during translation? A.CCG-ATA-GGC-CAA B. CCG-AUA-GGC-CAA C. CCG-UAU-GGC-CAA D.CGC-AUA-GCG-CAA •Which of these resulting strands explains the kind of strand formed during DNA replication? A. GGC-UAU-CCG-GUU B. GGC-TAT-CCG-GTT C. GGC-AUT-CCG-GAA D. CGC-AUA-GCG-CAA •What resulting strand will form after DNA is transcribed to form mRNA? A. GGC-UAU-CCG-GUU B. GGC-TAT-CCG-GTT C. GGC-AUT-CCG-GAA D. CGC-AUA-GCG-CAA
I have heard that covid 19 vaccine can bring changes into our dna is it right or wrong someone plz guide me thankx
Best video on gene mutation
@shomusbiologyofficial
Жыл бұрын
Thank you
You are nice teacher
@shomusbiologyofficial
4 жыл бұрын
Thank you
It's really helpful 😊 thanks a lot... I have a suggestion sir , please conduct a tutorial about mutagen .. physical, chemical and biological ... Please... 🙏🙏
@shomusbiologyofficial
3 жыл бұрын
You're welcome
@swathisuresh4758
3 жыл бұрын
@@shomusbiologyofficial 👍
Legend ❤️
Well explained
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Sir there is question in the book.. Is it possible to say when a gene will mutate?
@bridgetfhelm
3 жыл бұрын
Usually during formation in the womb when it’s a genetic mutation. You are born with it. But the “symptoms” don’t always appear until later in life. My husband and daughter have a rare genetic mutation where at a splice site there is a T where there should be a G. Only my husband has mild symptoms of the mutation so far. Nothing anyone would notice - just a few small skin tags.
Thank you, but I have a question, how mutation (which is almost all bad)is the basis of (evolution)?
@shomusbiologyofficial
3 жыл бұрын
It can be good too
WHY do genes mutate, what are the mechanisms and factors in the frequency?
@tuniyabeemroth1140
5 жыл бұрын
Genes mutate by these factors like-:(1)temperature may cause changes.(2)alpha,beta,gamma rays and so on.....Hope ur doubt may clear
Nice way of discribe
@shomusbiologyofficial
5 жыл бұрын
You're welcome
Thanks for the class 🙂
@shomusbiologyofficial
2 жыл бұрын
You're welcome
Sir please help us to learn about Pcr amplification
@shomusbiologyofficial
4 жыл бұрын
Video is already there
Sir provide biotechnological concept related pharmacy
@shomusbiologyofficial
4 жыл бұрын
Okay
Thank u bhaiya☺️😀😀😀😀
@shomusbiologyofficial
5 жыл бұрын
You're welcome
thanku
@shomusbiologyofficial
2 жыл бұрын
You're welcome
So helpful 🙂
@shomusbiologyofficial
Жыл бұрын
Thank you
@Rupsa292
Жыл бұрын
@@shomusbiologyofficial U r wlc
সমু আপা, আপনি কি সিগারেট খান, আমার মনে হয় ,যারা সিগারেট খায় তারাই এত সুন্দর করে বোঝায় আপনার ভিডিও দেখে মাস্টার্স র প্রথম বর্ষের পরীক্ষা এ 71% পেয়েছি, তৃতীয় হয়েছি এবার ও হবো💕🙏
Right
Thank you sir
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Sir please explain Hprt assay
Sir mutation pr Hindi m video bnaye n please🙏 apke smjhane se bhot acha smjh ataa h please sir🙏
@shomusbiologyofficial
4 жыл бұрын
Sure
@princekumar2021
4 жыл бұрын
@@shomusbiologyofficial thank you sir😇😄
❤️❤️👌👌👌 impressed..
Subtitle we need subtitle plz
Thanks bro 🇮🇳🚩💚
@shomusbiologyofficial
5 жыл бұрын
You're welcome
Some of the chenal make very long video that make me feel scary to learn. But this video is great
Keep it up👌
@shomusbiologyofficial
4 жыл бұрын
Thank you
Does the deadpool touture method work?