General Embryology - Detailed Animation On Second Week Of Development
Implantation of the blastocyst usually occurs 6-8 days after fertilization.
By day 8, the blastocyst has burrowed into the uterine wall, being completely embedded by day 9.
Day 8
The blastocyst is composed of two main components: the outer cell mass, the trophoblast; and the inner cell mass, the embryoblast.
As the trophoblast makes contact with the endometrium, it differentiates into two layers: an inner, cytotrophoblast; and an outer, syncytiotrophoblast.
The embryoblast differentiates into a bilaminar embryonic disc composed of two cell layers, the hypoblast, and the epiblast. Soon after the embryonic disc has formed, a cavity begins to appear between the epiblast and cytotrophoblast, known as the amniotic cavity.
Cells originating from the hypoblast begin to migrate, forming a thin membrane, which lines the inner surface of the cytotrophoblast. This is called the exocoelomic membrane. The exocoelomic membrane and cells of the hypoblast together form the walls of the primitive yolk sac.
Day 9
Once the blastocyst is completely embedded in the uterus wall, a plug called a fibrin coagulum forms in the gap created in the epithelium of the uterus by the blastocyst. At this time, the growth of the cytotrophoblast and syncytiotrophoblast is much faster than that of the bilaminar embryonic disc
Small holes called lacunae begin to form in the syncytiotrophoblast as it continues to expand.
Day 12
Capillaries in the endometrium surrounding the developing embryo dilate, forming maternal sinusoids. As the lacunae continue to expand, enzymes within the syncytiotrophoblast begin to erode the lining of the sinusoids and uterine glands. This allows anastomosis between the maternal sinusoids and lacunar networks to begin establishment of an uteroplacental circulation.
By day 12, the lacunae stop growing and fuse to form large interconnecting spaces, called lacunar networks.
A new population of cells appears between the inner surface of the cytotrophoblast and the outer surface of the primitive yolk sac, known as the extraembryonic mesoderm.
Large cavities begin to appear in the extraembryonic mesoderm. These gradually fuse to form one single cavity, called an extraembryonic coelom.
Day 13
Approximately 13 days after fertilization, a large portion of the exocoelomic cavity is pinched off, forming a smaller cavity, called the secondary yolk sac. A remnant also forms within the exocoelomic cavity, known as an exocoelomic cyst, which is eventually eliminated.
By the end of the second week of development, the chorionic cavity enlarges, and the bilaminar embryonic disc is joined to the trophoblast by a band of extraembryonic mesoderm called the connecting stalk.
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In the textbooks, there is so much stuff happening at the same time with the development of the embryo and of the formation of the future placenta, it can be confusing. So I love how you highlight what cells you are talking about and make all the other ones get a bit faded each time, so we know which specific layers you talk about. makes it so much clearer!
Thanks thanks thanks I have exam in 3 hrs and it’s 5:30 am am studying all night procrastination FTW. (medical school btw...)
@muhammadraza2766
4 жыл бұрын
Did you pass then
@rayzins6373
3 жыл бұрын
@@muhammadraza2766 need to know this as well
@ahmadyounes4102
3 жыл бұрын
Same!
@ogunladewilliam
2 жыл бұрын
Same as you bro
@jasmitkaurpuri
2 жыл бұрын
I have an exam in 30 mins exact
Almost 3 years in medical school and this is my first time understanding this. I genuinely don't know how to feel. Thank you very much. I'm grateful.
Thanks a lot!! It helped me to understand what my textbook couldn't do!!
Jazakullah. This topic is very tough but this video make it very very easy for me.
@kalidar8215
8 жыл бұрын
+Wajahat ullah zakori agree
@None-fr1fi
5 жыл бұрын
what does it mean "wajahat ullah zakory"? 🤔
@M7mdx3zz
4 жыл бұрын
رهَــفْ وجاهة الله زكوري
@Dr.Abdullah_Dubai
3 жыл бұрын
@@None-fr1fi his name 🙄
The second week is the most confusing one
It's mind blowing for me that you can learn so much in just 4 minutes.I mean this is the first time that it makes sense to me and what I couldn't understand in 5 years of med school. It's amazing how much output you get with a little effort. KZread is the way to go.👏👍
@giftofthewild6665
Жыл бұрын
This seems very simplified, less detail than you would receive in med school surely?
@royalroamer1
2 ай бұрын
@@giftofthewild6665yup, definitely
@royalroamer1
2 ай бұрын
@@giftofthewild6665im in first year and its already way more than this lol 😂 (wish me luck)
The clearest explanations ever! I'm a french MS and I seem to struggle with this chapter as much as my fellow "international" MS. So much details and precise steps to learn. So thank you.
@shh0hhdysf277
2 жыл бұрын
I am a dental student and embryology is making me losing my mind
OMG that was amazing please continue
lifesaver.... i cannot thank you enough for your well illustrated video lectures on Embryology...
Thank u so much for this video, I`m would like to watch the third week. Amazing Job !
this is the best!!!! This is highly recommended for everyone who has issues with understanding large unclear stuff regarding embryonic development .
Thank you so much, this is brilliantly explained and visualized!
This is a really nice explanation! thank you guys!!
Thank you so much ! What a clear, simple explanation for such a complex process. helped a lot!
this did for me what lectures could not do. thank you for posting!!!
Thank you so much for this video.
THE BEST VIDEOOO about the Development. It´s so complicated but you explained it so easily. Thanks a lot 🌟🌟
I really liked the concept of the video. It is so much easier to understand such concepts through animations. Videos have made it so much easier for us. More videos of this sort should be uploaded. Keep up with the quality content. I hope you all the best. I am planning to opt for IVF process. I hope it works out for me.
PLease keep posting videos!!! they are great!!! we are waiitng for the 4th week embryology video!!
Concise explanation of the embryonic cavities. Thx!
thank you, to be honest when i saw this videos, i really understood the embryonic development
it's awesome *o* ... students need people like you ! Thank you so much
it is nice and helped me to understand the concept easily
amazing video . thank you for put it here...
So helpful,thanks
100% detailed and yet so short. Legend
@vacaspen5038
5 жыл бұрын
This is like mint this information and attitude and attitude. Of course there's space between my eyes of course there's space in your veins so that the blood can Roo but it's all one organism. I'm into lies. So yes the capillaries of the womb net to the embryo which already implanted to fuse as one.
Thankyou so much the best video I have seen so far 👍🏼👍🏼👍🏼
Yoou guys just made it a lot easier for me. Thanks!
That was quality! Thank you!
Thank u so much. This saved my life!!!! THANK YOU SO SO SO SO MUCH
you literally saved me ... its 2020 now AND THANKS
JIZAKALLAH ♥️ i can not explain u people how much it has helped me thank you soooooo much.may ALLAH bless you guys and keep it up ♥️
Thank you for the details description ☺️🙏
Hi I am a med student from Turkey and I am very thankful to you because of this video. Because I read my notes lots of time but I couldn’t understand. But now ,I can understand it. This video helped me even it upload 6 years ago. Thank you! (Sorry for my grammar mistakes)
amazing video!!! everything makes sense now! 😮😮😮❤❤❤
@mohamedelyastube5932
6 жыл бұрын
fussilat.org/category/english-articles/
@mohamedelyastube5932
6 жыл бұрын
fussilat.org/category/english-articles/
Best of the best!👍🏻
thank you so much for this wonderful video!
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This was so good. I just, thanks. Thanks a lot. Love from Kenya.
@mohama698
5 жыл бұрын
I love Kenya
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this video makes it so easy nice job!!
VERY SO MUCH THANK YOU IT IS FIRST TIME WHEN I AM ABLE TO UNDERSTAND THE THINGS..ONCE AGAIN SO MUCH THANK YOU
Excellent explanation.🌟
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marvellous explanation thanks alot😊
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JazakAllah
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Very grateful
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It would be amazing to have a PDF/storyboard of this video with detailed labels to study from :D
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