Johnny Depp: Captain Jack Sparrow
Orlando Bloom: William „Will“ Turner
Geoffrey Rush: Captain Hector Barbossa
Keira Knightley: Elizabeth Swann
Jack Davenport: Commodore James Norrington
Kevin R. McNally: Joshamee Gibbs
Jonathan Pryce: Gouverneur Weatherby Swann
Lee Arenberg: Pintel
Mackenzie Crook: Ragetti
Damian O’Hare: Lieutenant Gillette
Zoe Saldana: Anamaria
Martin Klebba: Marty
David Bailie: Cotton
Lauren Maher: Scarlett
Vanessa Branch: Giselle
Giles New: Murtogg
Angus Barnett: Mullroy
Greg Ellis: Commander Theodore Groves
Isaac C. Singleton junior: Bo’sun
Treva Etienne: Koehler
Vince Lozano: Jacoby
Trevor Goddard: Grapple
Brye Cooper: Mallot
Michael Barry Jr.: Twigg
Ralph P. Martin: Mr. Brown, der Schmied
Paula J. Newman: Estrella