Minor correction: Eukaryotic RNA polymerases have ~12 subunits (in the video at around 11:20 I wrongfully said that it is ~26). I confused 26 from the fact that it is the number of YSPTSPS repeats in yeast CTD (humans have 52 repeats, yeast have 26). Additional fact: Plants also have RNA polymerase V that is involved in a similar non-essential function as RNA polymerase IV. To read more about them, check out www.ncbi.nlm.nih.gov/pmc/articles/PMC4618083/

@sathiyalakshmi.p8280

4 ай бұрын

Lewins ✌️

I love the animation, so clean and neat! The video is def underrated, learnt alot, thank you!

excellent explanation all details in a single slide

this was really helpful , with all the information and notes. Thank you !!

very helpful and informative. I really need this video a lot.

The best explanation there is on KZread for transcription ....... I've searched for a video like this for quite a time now and i finally found It.....Thank you soo much

@theCrux

3 жыл бұрын

Glad it was helpful! :)

Watching your channel makes me secrete serotonin !!! Thank you ...

@theCrux

Жыл бұрын

I am glad it is helpful and enriching your education :)

thxu so much, really help!

The best explanation!! Thanks

@theCrux

2 жыл бұрын

Glad it was helpful!

thank u so much

ossum explanations Keep it up, great work ✌👌👏👍

@theCrux

4 жыл бұрын

Thanks a lot 😊

Nice explanation.

@theCrux

4 жыл бұрын

Glad it was helpful! :)

amazing thank you 🌷🌷🌷🌷

Your content is best... I learnt my entire semester from your videos..... Great job... I shared this video to my class group 😇😇

@theCrux

2 жыл бұрын

Thanks a lot 😊 It brings me great joy to hear that the content has been useful.

Thanku

Thank u for right to the point and very informative sharing this save many students time n future better than my professor lecture! ☝️🙏🎃🎃🎃Happy Halloween!

@theCrux

3 жыл бұрын

Glad it was helpful!

Omg......can't tell in words....finally it was a great great video.. Thanks a lott and expecting more such videos...I have watched other channels...but this was the best. thank you very much

It must be that mRNA produced must be in 3 to 5 direction, complementary to DNA template strand

Sir,I have a question : the RNA polymerase works in 5 to 3 direction of DNA template, then y does it produce mRNA in the 5 to 3direction???

@theCrux

3 жыл бұрын

RNA polymerase moves from 3' of the template to the 5' - the resulting RNA has 5' end coming out first (so the RNA is 5' > 3'). The chemistry of synthesis is such that you can only synthesize nucleic acids in 5' > 3' direction. The enzyme on the other hand may move in either direction. Check out 'Strand Notations' at 2:52 in this video kzread.info/dash/bejne/aZ-a08eCmqzgfbw.html&ab_channel=theCrux

Hi, thanks for the super-useful video! A small doubt: Why rRNA is most abundant in the cell compared to mRNA and tRNA? Can we tell because most mRNA gets converted to proteins and is unstable when not bound to ribosomes. But rRNA are stable as they are bound to ribosomes?

@theCrux

8 ай бұрын

Ribosomes are in excess of mRNAs. mRNAs tend to be reused to make proteins - same mRNA can be used for translation for as long as it is around in the cytoplasm, so you don't have a lot of them to begin with. Typically you have around 100k - 300k mRNAs per cell vs millions of rRNA because you have way too many ribosomes. The excess of ribosomes means translation is immediate.

@sandhyavasudevan3165

8 ай бұрын

@@theCrux Oh... understood. Thanks for clarifying!

You know, if only that scientist named the transcription factors alphabetically instead of that weird arbitrary rules this wouldn't be that hard lol

Your hand writting are verry small to read. Make it bigger

@theCrux

2 жыл бұрын

Thanks for the feedback. I will try to make it bigger.