End-organ resistance to PTH ( pseudohypoparathyroidism ) - USMLE Pathology

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End-organ resistance to PTH (pseudohypoparathyroidism) - Pseudohypoparathyroidism (PHP) refers to a group of heterogeneous disorders defined by targeted organ (kidney and bone) unresponsiveness to PTH. PTH resistance is characterized by:
●Hypocalcemia
●Hyperphosphatemia
●Elevated PTH concentrations

Пікірлер: 16

  • @ismailelghuwael6859
    @ismailelghuwael68593 жыл бұрын

    At the end of the video. Pseudohypoparathyroidism, increased not decreased PTH. Thank you

  • @doctorbhanuprakash

    @doctorbhanuprakash

    3 жыл бұрын

    Yes slip of the tongue,,

  • @Trafie307

    @Trafie307

    7 ай бұрын

    @@doctorbhanuprakashyour slip of tongue created so many confusions

  • @sadafmunir2278
    @sadafmunir2278 Жыл бұрын

    Isn’t it an autosomal dominant disorder?

  • @Aman-hg6jq
    @Aman-hg6jq6 жыл бұрын

    One important aspect to note here is that ABO is not a condition, it is a skeletal phenotype. Also it is important to note that the Gs defect (could be due to a GNAS gene defect) results in low levels of cAMP generation in kidney or bone.

  • @daliapimentel853
    @daliapimentel8535 жыл бұрын

    This is an awesome and really helpful video! Also the way it's explained is really understandable.

  • @nooramtulgm8481
    @nooramtulgm84818 күн бұрын

    Thank you so much

  • @jameslovescars
    @jameslovescars Жыл бұрын

    I have Pseudohypoparathyroidism type 1B and the only medication that can help regulate calcium levels effectively for me is calcitriol. But it doesn't stop me feeling extremely tired 99% of the time. 😥

  • @Hafsa-el2me
    @Hafsa-el2me4 жыл бұрын

    It’s autosomal dominant

  • @faisalnoor3061

    @faisalnoor3061

    3 жыл бұрын

    Lab findings?

  • @YASIR-zr7ot

    @YASIR-zr7ot

    2 жыл бұрын

    true

  • @dr.prateekagrawal5727
    @dr.prateekagrawal57275 жыл бұрын

    Jandar sir keep it up

  • @abdurrahman-ir3fw
    @abdurrahman-ir3fw2 ай бұрын

    Isn't autosomal dominant??

  • @k.kucukgozlu
    @k.kucukgozlu2 жыл бұрын

    Thank you sir great video

  • @doctorbhanuprakash

    @doctorbhanuprakash

    2 жыл бұрын

    Glad you liked it

  • @Julinna_the_gamer
    @Julinna_the_gamer2 жыл бұрын

    Thanks but Increased PTH level