Learning about replication without actually seeing it makes actually no sense. A must watch for anyone studying biology-related sciences.

@8ThatUp2

5 жыл бұрын

Yess! I really needed to see the process, because I was getting confused while I was reading about it in my textbook.

@mrunmayijadhav6414

5 жыл бұрын

This is just an animation 😂

@siddharthjadeja6991

4 жыл бұрын

Yea bro

@rainylight6268

4 жыл бұрын

Same. I'm having a bit of trouble actually understanding this process and remembering it.

@CaRrIcKCc19

4 жыл бұрын

*Boomer af comment incoming* Imagine not being fortunate enough to see it like this? The original G's must have done a whole lot of figuring out to get here.

Anyone else here because their professor cannot explain things simply?

@ahmadranaahmad7077

6 жыл бұрын

Yasmine Vella i am here because of this

@DarkMatterr

6 жыл бұрын

I am. Seeing it in action is a much easier way to visualize it in the test.

@catalinabarbosa3041

6 жыл бұрын

Actually... You discovered me ._.

@Ellen_Seokjin

5 жыл бұрын

ya

@hreshapatil1722

5 жыл бұрын

here cause I did not pay attention in class

Almost 8 years ago and this is one of the best DNA replication videos I've ever seen so far! Great visualization!

2024 attendence here ❤

@joteam1404

Ай бұрын

First 🎉❤

@Mr.minecraft

Ай бұрын

Here!

@ihesiabavivian8966

Ай бұрын

How long ago was this uploaded ???!!!

@shiamaaismailmohammed3587

13 күн бұрын

🙋🏻‍♀️hi

@LeroyRussell-rp3df

6 күн бұрын

🎉

As a senior bio major I shed a tear watching this... so beautiful

@noora9690

2 жыл бұрын

why the dramatics

@hobbiesofamuslimgirl

2 жыл бұрын

love that energy loll

@aimansayed736

2 жыл бұрын

lol

@bitoffbalance4021

2 жыл бұрын

I understand why . It sounded so messy in our classes , this is fantastic explanation and visualisation

@KO_Manic

2 жыл бұрын

Bit dramatic but okay! 👍

Here is a basic & simplified version of the video: BASICS: Adenine --> Thymine Cytosine --> Guanine PREPARING TO REPLICATE: -Helicase splits the DNA for replication -Primase adds RNA bases (primer) to the leading strand. -Why does DNA polymerase require a primer before it adds DNA nucleotides? It is because the RNA primer will have a free -OH group at the end that it can nucleotides to! -DNA Polymerase binds to the primer to start replication! REPLICATION: -The leading strand TEMPLATE will have a daughter strand that is created 5' to 3', in the direction of the REPLICATION FORK (where DNA becomes uncoiled). -The lagging strand TEMPLATE will have a daughter strand that is ALSO created in the 5' to 3' direction, but it will replicate in the OPPOSITE direction of the REPLICATION FORK. -That's not okay! Because it is in the opposite direction of the replication fork, it needs to be made in fragments (Okazaki Fragments). FINISHING TOUCHES: -Exonuclease removes the RNA primers that were added to the start. We don't want RNA in our DNA! -DNA polymerase then adds DNA bases to the missing spots where the RNA primers were. -Ligase makes sure all the fragments are sealed CLOSING: -DNA is described as semi-conservative because there is one old and one new strand of DNA in each DNA. Thanks and hopefully this will help you for your bio test I know it did for me :)

@jacksonsullivan7309

3 жыл бұрын

thx

@velvetbar9388

3 жыл бұрын

Thank you so much! This helped a lot!! Really appreciate you putting the transcript out here :))

@livingmybetsylife

3 жыл бұрын

@@velvetbar9388 You're welcome!

@hollywooddhamaka6018

3 жыл бұрын

Sukriya mere Bhai

@shmooveyea

3 жыл бұрын

The video was the simplified version.

حيا الله طلاب السادس العلمي بويه Final year high school students in Iraq welcome you 🥲🇮🇶

@KimtaeHyung-ig8nv

Күн бұрын

ها رضا طمنا اشونک ویا الامتحانات ؟؟

Step 1: Helicase Function: Helicase is the initial enzyme in DNA replication. Its primary function is to unwind the DNA double helix. It accomplishes this by breaking the hydrogen bonds between the complementary base pairs, such as A-T and G-C. By doing so, helicase separates the two DNA strands, creating what is called a "replication fork." This single-stranded DNA region is where the actual replication process will take place. Step 2: Primase Function: Primase follows helicase. Its role is to synthesize RNA primers. Primase adds short RNA sequences, known as primers, to the DNA template strands. These primers are essential because DNA Polymerase, the enzyme responsible for adding new DNA nucleotides during replication, can only extend an existing strand. On the leading strand, primase synthesizes a single RNA primer at the 5' end, providing a starting point for DNA Polymerase. Step 3: DNA Polymerase III Function: DNA Polymerase III is the primary enzyme responsible for DNA synthesis during replication. It adds nucleotides to the growing DNA strand. On the leading strand, DNA Polymerase III synthesizesthe new DNA strand in a continuous manner by extending from the 5' to 3' direction, using the parental DNA strand as a template. This strand doesn't encounter the same challenges as the lagging strand, which requires a more intricate process. Step 4: Exonuclease Function: Exonucleases come into play after DNA Polymerase III. Their function is to remove RNA primers from the DNA template. Once the RNA primers are synthesized by primase, exonucleases degrade them, creating gaps in the DNA strands. On the lagging strand, multiple RNA primers are synthesized at different points along the template to provide starting points for DNA Polymerase. Step 5: DNA Polymerase I Function: DNA Polymerase I is an enzyme responsible for gap-filling. After the removal of RNA primers by exonucleases, DNA Polymerase I replaces the RNA nucleotides with DNA nucleotides. On the lagging strand, DNA Polymerase I works in a discontinuous manner, filling in the gaps created by the removal of RNA primers and synthesizing short DNA fragments called Okazaki fragments. Step 6: Ligase Function: Ligase is the final enzyme involved in DNA replication. Its function is to seal the nicks or gaps in the DNA backbone. It does so by catalyzing the formation of phosphodiester bonds between adjacent nucleotides. On the lagging strand, ligase joins the Okazaki fragments together, ensuring the integrity and continuity of the newly synthesized DNA strand. In conclusion, DNA replication involves two strands: the leading strand, which is synthesized continuously, and the lagging strand, which is synthesized discontinuously in Okazaki fragments. Different enzymes work together to ensure the accurate replication of both strands, preserving genetic information during cell division and ensuring the inheritance of genetic traits.

@zwafar

Ай бұрын

Isn't it Pol delta in Eucaryote model ?

Take notes, biology teachers. This is how you teach this.

@arpita003

3 жыл бұрын

👍🏻👍🏻

@beatrizzzzalves

3 жыл бұрын

biology teachers are not graphic designers

@chiaramartin8426

3 жыл бұрын

@@beatrizzzzalves they probably mean pulling up videos and lots of imagery so there's a visual element making it easier to understand

@ayushraj.9808

3 жыл бұрын

There's another amazing video regarding steps of DNA replication. You must check it once. I hope this might clear all your doubts. Links here. kzread.info/dash/bejne/oZVqycyJiraYm84.html

@rafikhn2817

3 жыл бұрын

In this video , idk if i didn't understand replication or not , but the enzyme at 2:41 is not supposed to be able to move that way( to take that direction), it is supposed to be linked with the second DNA polymerase and take same direction. Sry for my english hard for me to explain hard lessons with a language i don't master.

Τhis was actually the only video that made me finally understand it..good job :)

@satya837

7 жыл бұрын

Lena D. plz watch replication on my channel I can bet its the best on youtube

@yourgenome

7 жыл бұрын

Erm, "Mr Biology" we'll take that bet. I think you'll find that THIS video is the best on youtube 😉

@mohitkumarsager3163

6 жыл бұрын

awsome and help ful

@saifgondal1277

6 жыл бұрын

I understood replication process in real sense by this video. Keep on.

@satyawanravish1513

6 жыл бұрын

I understood...But how to write it for exam...

Any neet student here😅

@ayat.1256

2 ай бұрын

Me😂

@roseee7692

2 ай бұрын

Yehh 😂

@dhivyalakshmi6718

2 ай бұрын

😂me

@azukitadummy6290

2 ай бұрын

Me 😂

@phantomgaming453

2 ай бұрын

Me😂

I'd lost all the hope that I'd ever understand replication, after watching this precise , short and easy-understanding video , I'm feeling refreshing now. Hats off to that person who made this...

My biology teacher explained really good and now seeing this video makes dna replication totally clear to me. Thank you!

@anonykitsune

2 жыл бұрын

let's switch brains please I'm dying we have exams tomorrow, my teacher explained it too fast for my brain to process it all TvT

@kaushikpradhan25

2 жыл бұрын

@@anonykitsune ikr this topic is really hard if we just try to read it- It requires high imagination power to actually visualise the whole process. Anyways don't worry too much and just think how beautiful the whole mechanism is. And all the best

@anonykitsune

2 жыл бұрын

@@kaushikpradhan25 our exams are finally done! I'm free!!😭😭😭 there are a few questions where our teacher didn't explained it 😭

@ronweasly778

2 жыл бұрын

My biology teacher explained this poorly and this video helped a lot

@DB-gl3jx

2 жыл бұрын

@@anonykitsune i get questions like that too, but i think it’s just to test your critical thinking of the particular subject. the questions contain info that i’ve studied, but it is worded in such a way that makes me confused af lol.

I’m French and I’ve understood it better in English because professors or unable to EXPLAIN IT CLEARLY IN A SIMPLE WAY !

@lisaitvvlv6519

4 жыл бұрын

Pareeeil

@chethan2668

3 жыл бұрын

Vaiva lè france

@isabelasantos6026

3 жыл бұрын

I had to do the same. I'm Brazilian

@-horoshilov-8272

3 жыл бұрын

@@chethan2668 dafuq

@katarinaekert8504

3 жыл бұрын

YESS me too... and i’m from Serbia 🇷🇸🤯

im literally crying because this is so good. merely reading the process just screwed me. thank you so much for the efforts.

@jaishankarmishra7585

5 ай бұрын

Absolutely! Very well explained 👏

That's a gem. Three & half a minute is more precious than three & half an hour without seeing the animation.

A 3.30 min video made me understand what 3 lectures of 2 hrs each couldn't !

i just passed my biology daily test today about dna after i watched this yesterday night. I wanna give you a BIG thankyou for helping me study☺

@jayviews5375

5 жыл бұрын

it's also useful for MBBS Students

@anshagrawal6289

4 жыл бұрын

@@jayviews5375 These things are also taught in mbbs? I thought it is only limited to school and then BSc at higher level

@jayviews5375

4 жыл бұрын

@@anshagrawal6289 Yes bro I'm now in 5th sem of MBBS...Its a part of Biochemistry

@anshagrawal6289

4 жыл бұрын

@@jayviews5375 Thank you for your information

@emma-tt3lw

3 жыл бұрын

not jungkook being everywhere i go ajhfaflfaf

this just brings me back to life and makes me forget every "imperfection" I think I have

I learnt DNA replication from ritu man seriously telling mam ki lecture ki baad animation ki jarurat nhi hote h pr m ne yeh dekha or bhi clear ho gaya❤️🔥why not school teacher teach like this ??? Fir bol te h bache nhi pdh te

This video is amazingly incredible. It is precise, up to the point and explains everything in 3:28 min with clear voice with synchronized animation. This video is the best that explains Dna replication on KZread. It probably deserves a million likes

@Lhiledhonkheh

2 жыл бұрын

fam youtube is not a learning app, this does not deserve 1mil

@stanleyhenry5953

2 жыл бұрын

@@Lhiledhonkheh roughly 50% of people on youtube use it to learn new things though

@Obibopbop

2 жыл бұрын

🙌

@babyzap8564

2 жыл бұрын

@@Lhiledhonkheh I use KZread for entertainment and education

@its_not_lux

Жыл бұрын

@@Lhiledhonkheh A stupid comment.

Only video that's straight to the point and explicitly states all the steps .. THANK YOU!

@abuzarsafi6934

5 жыл бұрын

Very nice vidio

@Annalyah

4 жыл бұрын

Yet still my homework doesn't make sense because I believe my professor simply wants us all to fail!

I love how the first strand replication process is very simple, while the second strand replication is 100x more complicated lol.

This video is super good in helping visualize the entire replication process. Although I think there was slight oversight in the direction of the DNA strand because in the beginning of the vid, the top strand was labeled 5' on the left side and 3' on the right side, but when DNA polymerase was introduced, the top strand was suddenly 3' on the left side and 5' on the right side.

Life is so perfect.

@felixalonzo2847

3 жыл бұрын

Life is no accidental explosion.

@unknownknown1653

3 жыл бұрын

yep

@chethan2668

3 жыл бұрын

Yeh

@gabi4205

3 жыл бұрын

Life isn't perfect. Otherwise why does DNA polimerase make so many mistakes and some lead to detrimental mutations? Why do cells suddenly abnormally proliferate and create tumours? I'll tell you what. Life isn't perfect. It's _good enough_ . Good enough that it can survive and thrive, but never perfect. Contemplating upon life itself and its mechanisms does not warrant the immediate conclusion of "this is no accident" or "someone _must_ be behind this". I suggest you step out of your initial reaction which may be corrupted and actually think critically for a second.

@ishootstar0

3 жыл бұрын

TrEs 2b the fact that DNA can correct itself is fascinating. The fact that something this small yet so complicated can happen in every cell is fascinating. It is logical and scientific to look for the source of something (existence). Just because you have an opinion, doesn’t mean theirs is corrupted and not critical. Life is perfect because of its imperfections. Idk what I’m trying to say exactly, but don’t force ur opinion on others :)

The best replication animation i have seen yet, thanks a lot!

@cjhepburn7406

4 жыл бұрын

Someone said these are really simulations.

@mimi-xw5se

4 жыл бұрын

@@cjhepburn7406 wdym ?

@sadanalmutairi1610

2 жыл бұрын

congrats on ur graduation!!!!!

I'm so glad I speak English. Here in Brazil we have amazing teachers, but i'm a more visual student, so it's a lot easier to learn with 3d videos

This 3 minutes video was more helpful than my madams 3 hours long class. Failed to understood a single word there Thanks!

Finally can understand how lagging strand is replicated. Thank you!

@afrahnaseerhussainmohammed1664

5 жыл бұрын

Ikr

@abdulrahmanalghothani3911

4 жыл бұрын

you are a bot

@chethan2668

3 жыл бұрын

Ikr

How on earth did someone discover this and all the details?

@Panthera-Uncia

4 жыл бұрын

The Almighty Lord created us, and also wanted us to know.

@arpita003

3 жыл бұрын

Ya & we hv to study this boring topic 🙂

@thimitha3723

3 жыл бұрын

more than 100 years of scientific research by a lot of different people

@ben_3256

3 жыл бұрын

Watson & Crick. Along with some help from The Almighty.

@stephanie154

3 жыл бұрын

Its beyond our intellect to assume that!

Amazing❣!!! You have nailed it in minutes. I love how you explained everything about DNA replication. It was perfectly matched with an animation that adds to the total presentation. Your video is fun to watch and easy to understand👏👏

I am an Egyptian student at my third secondary school year and this video helped me to imagine and understand a topic in my curriculum. Thanks a lot!

I don't understand why teachers can't explain like this ; slow and straight to the point . All they do is draw a diagram ( totally not realistic ) and ask us to write notes . And we are like lol what just happened .

@TomeRodrigo

3 жыл бұрын

Not everyone has a gift to be a teacher...for being a good teacher you have to have empathy so you are able to imagine yourself walking in shoes of another person, therefore, you are able to explain things extremely well as you are imagining how they will perceive the given information.

@chethan2668

3 жыл бұрын

They are dumboo

@bitoffbalance4021

2 жыл бұрын

My teacher explained wayyy too many details which made us all confused . Single strand binding protein , increasing efficiency of dntp addition ,etc. All gone over the head

@chanikarkare727

2 жыл бұрын

@@bitoffbalance4021 Can relate, totally ....

@bitoffbalance4021

2 жыл бұрын

@@chanikarkare727 are you in medical College now?

It's so interesting to know how our body is made so intricately and it functions in a way that is beyond anything that we would make artificially.

@noodlepoodle287

2 жыл бұрын

Yeah. That’s why I love biology

@RASTstudio

Жыл бұрын

it seems that we were not created by accident. We are created by the All-Knowing One who created the universe

@Qwertyuiop21554

Жыл бұрын

@@RASTstudio Allahu Akbar!

@RASTstudio

Жыл бұрын

@@Qwertyuiop21554 MashaAllah, Assalamu Alaykum. I thought you were not muslim

@Qwertyuiop21554

Жыл бұрын

@@RASTstudio Wa alaykum Assalam

Very easy to understand whole process of DNA replication through this video...thanks a lot😊

this is the best explanation I've ever watched!!

my mind is blown this is the 100th video ive watched tonight and it is the only one i understood god bless

@hobisaysmumbletumble551

5 жыл бұрын

Amazingme liking the pfp ;)

@trevorlei4096

5 жыл бұрын

hobi says mumble tumble lol no

@ghostqueen2310

4 жыл бұрын

ARMY with science

@ganeshpandav9586

4 жыл бұрын

Jiminah

@cjhepburn7406

4 жыл бұрын

Starsbless

This was by far the best video I've seen of this. Straight and to the point, no annoying music, and simple visuals. Absolutely fantastic!

Very helpful animation! Thanks for visually showing the difference between an RNA primer and an Okazaki fragment; that made it easier to understand.

@thebiocracker504

3 жыл бұрын

kzread.info/dash/bejne/oWaV1LlpfK3WgNo.html Watch this video to know the detailed mechanism of DNA replication

The best guidance for DNA replication and anyone can understand smoothly...Thank you

I think that my biology teacher didn’t actually know how to explain this so he just resorted to this video lol

@arafatasilkan5247

4 жыл бұрын

Same here!

@harshpratapsinghkushwah8710

3 жыл бұрын

Same here

@user-fn2pt4ui1p

3 жыл бұрын

Why not

@sphia1239

3 жыл бұрын

same lmao

@andij605

3 жыл бұрын

Look at the bright side: at least he has self-critique. I'm re-learning biology over a decade after leaving high school, cause I was always interested in it, it's just all my teachers were... Bad. lol

Easily the best replication video I've seen to date, thank you. I don't understand why it's so difficult for professors to explain this in a simple step by step process. I get that it's a complex topic, but damn, just go step by step. Stop talking about random enzymes in no discernible order.

@mashihuzzaman1962

2 жыл бұрын

ikr

しっかり海外でも岡崎フラグメントになってるのなんか感動

@sanfrancisco9336

Жыл бұрын

🐴🐴

this video made me understand the dna replication in a perfect way, the animation is amazing and made it easier to understand especially in the part where the replication is in the opposit direction it was hard to get it at first but after this video i found it actually so simple. thank you for this amazing explication, well done.

As a science teacher this is by far the best replication video out there. Thanks for the clear description!

@sciencevigyan

2 жыл бұрын

Go to my youtube channel there you will get full explanation with animation.

As a 3D artist, I feel it’s awesome to see these types of animations being used in education. Keep up the great work!

@abdulrahmanalghothani3911

4 жыл бұрын

anyone with an exclamation mark is scripted

@TheBanjoShowOfficial

3 жыл бұрын

@@abdulrahmanalghothani3911 amen to that

@blairemugumya938

10 ай бұрын

Aww wow, it's so helpful

Fantastic explanation...every time before my exams I use to watch this video for better clarity...

My professor litearlly took 8 lessons to explain this process and almost nobody got it, it’s way simpler than I thought thank you

After 20 minutes of watching videos and re-watching them, this one did the most at helping me understand the process.

한국어 자막 달아주신분 감사합니다 덕분에 잘 공부하고 갑니다

@john-yk5ri

3 жыл бұрын

Sábias palavras

@user-xr7wy2cd6w

3 жыл бұрын

^^도움이 되셨다니 다행입니다~

This is the best explanation I could've ever got for DNA Replication🔥🔥🔥🔥

This video is so wonderfully helpful. I was struggling thru diagrams in the text trying to get all the weird terms to stick and this is exactly what I needed to see and how I needed it explained. Thants!

Best video ever to show DNA replication! No other video that I could find really explains in a short but well detailed manner. Other videos I feel are for those who are already familiar with the process. This is my first year learning this process and I'm grateful I found this video!!

What took Biology 12 between 3 - 4 weeks to explain, explained in 3 minutes. All I’ve got to say

@TheBanjoShowOfficial

3 жыл бұрын

then you're clearly not paying attention in class because let me tell ya bud, this is not all that is discussed in biology. not even close actually.

One of the best videos on the internet, so underrated

Absolutely a great video 😍 was unable to understand replication process but this animated video has put away my all confusion 👍

The old but gold DNA replication 😁 This is so inspirational. Thank you so much, It helps a lot in learning, but also revising.

This was very helpful, I've been studying this for a few days now but I've always had a fuzzy picture of how the lagging strand is formed. Your video cleared everything up. Thank you!

My god this 3 minute video single handedly gets me though the exam. Thank you so so much for ever making this video.

Best and easy way to understand and better than protracted videos

Excellent animation. I wished it showed how topoisomerase did it's work in separating the overcoiled knots of daughter DNA strands.

@DilloYT-jl8fw

3 жыл бұрын

Just imagine it doing what helicase is It breaks, swivels and rearranges DNA to release tension made by action of helicase

Out of all the DNA replication videos this one is so good, very detailed and easy to understand thank you

Thank you so much, I had to learn for my biology exam today and this video made things al lot easier to understand!!

one of the best videos on KZread NO CAP

This is sooooo amazing with 3d visualisation I have chills when watching this... Gonna watch 9-10 times probably to remember it better...

I must say, for the very first time I can really understand what DNA replication is all about.... Thanks a lot for such a amazing video

This video single handily helped me finally understand the process.

ty alot guys your explanations are as clear as crystal ! neat !

Wow you are a life safer. Thank you so much. This animation should be shown in every biology class on this topic. Edit: I suggested it to my teacher. It might have an impact. Good job!!!

Such a short clip is worth more than a thousand books.

Perfectly summarises everything.

The best genetics video I've watched so far

Short and concise! Best explanation I found so far on the internet. It also shows how easy it is for this process to make small mistakes hereby distorting the DNA replication process with all the consequences that follow.

정말정말정말 감사합니다 Thank you sooo much 자막 달아주신분두요ㅜㅜ

Wow, what an amazing video! Incredible animation of this complicated process...helped me a lot with my schoolwork.

That's the video I was looking for...excellent animation

can't believe i haven't found this earlier after so much of my time wasted trying to look for a simple explanation like this. thank you so much i finally understand it.

My life I must be a visual learner this is the first time i have ever had a clue about the lagging strand

3 minutes and you made everything clear luv uuuuu

Simple explanation. Beautiful animation. I couldn't possibly wrap my mind around this Okazaki business before I watched this.

this is so magical that i can’t stop rewatching

@lavinia8238

3 жыл бұрын

nereyi kazandın ?

Biology teachers should learn how to teach replication and some other topics soo easily as in this video. Finally I understood Replication with the help of this video. Thanks a lot 👍👍👏👏😊😊

@DB-gl3jx

2 жыл бұрын

it’s because visuals/animations are much better at helping you understand scientific processes like dna replication than just explaining it in words. it makes a blurred picture much more clearer.

Simple and comprehensive video .. At first I thought it was an obscure concept , but after watching this video I got it...

this was way better than what i understood in class so thank you!

This is one of the best videos for explaining DNA replication, thank you!

One of the most helpful video I've ever seen. Thanks for it.

Best video ive seen on DNA replication!

Isn't this enough to give us a thought about why r we created so perfectly ?

hands down the best video explaining this concept, and trust me I looked at lots

Extremely helpful! You have done a wonderful job. Thanks a lot.

Learned more from the 3 minute video than I did from my professors 2 hour long lecture that mainly consisted of word vomit and pointing at words on a PowerPoint. Thanks

I said it and repeat : It's the best type of explanation ever.

Finally I'll be visualize the process of DNA replication

Best animation ever,and the lady was explaining very good👏👏👏👏👏👏👏👏👏👏

映像で見るとやはり分かりやすい。復習する際にも、動画で流れを確認すると思い出しやすい。

A very easy and clear way of understanding this, thankyou

Thank you very much! very simple explanation. I used this video for my genetics exam and it was very useful

So much easier to understand when its visualized

so simplified and yet all points covered I will cry buckets right now .

Beautiful. I am in love with these videos. So easy to understand for a concept I have been struggling to understand for a long time. A big thank you to the one who took pains to make this video. Please keep providing students with such useful concepts in easy form.