Desmopressin (ddavp): Nclex-rn Question Review
If you're NEW subscribe! → goo.gl/n2b5aj
In today's video we'll review desmopressin, a synthetic hormone used to treat nocturnal enuresis and certain clotting disorders. It may be given in the nose, by injection into a vein, by mouth, or under the tongue. Desmopressin works by limiting the amount of water that is eliminated in the urine; that is, it is an antidiuretic.
It works at the level of the renal collecting duct by binding to V2 receptors, which signal for the translocation of aquaporin channels via cytosolic vesicles to the apical membrane of the collecting duct. The presence of these aquaporin channels in the distal nephron causes increasing water reabsorption from the urine, which becomes passively re-distributed from the nephron to systemic circulation by way of basolateral membrane channels.
Desmopressin also stimulates release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
Thanks for the support, and make sure you SUBSCRIBE for more NCLEX question reviews!
Follow the channel on:
IG: / nurseessentials
Twitter: / nurseessential
Facebook: / nurseessentials
Media: #howtopassnclex .
.
.
#howtopassnclex #oxygentherapy #nursingstudent #nursing #nursingschool #nursinglectures
Пікірлер: 24
Technically, it could cause headaches, as an adverse effect that may occur is hyponatremia. One of the s/s of hyponatremia is headache.
It's the medication that I look for. I have two years with this problem. Around this two year, I've woken up to urinate 3-4 times during my sleeping hours, and recently I've woken up 4-5 times to go to the bathroom to urinate. I feel that it is arruining my life; that it is destroying me 😫
@FernandoMathias-nn5qy
10 ай бұрын
take or have taken antidepressants?
@HeyYall398
8 ай бұрын
Are you saying this medicine is destroying your life?
Thanks! My doctor said I can think about taking it so i wanted more facts and understanding.
@NursingEssentials
2 жыл бұрын
Glad it was helpful!
is it an acid or base ?
ушбу малумотни узбек тилида беринг
One of the best vid breakdowns I've seen. Not too many vids though. Good job nonetheless
@NursingEssentials
5 жыл бұрын
Thank you very much for your comment! We're glad to know this video helped!! We are working on more videos, stay tuned!!
Awesome 👏
@NursingEssentials
5 жыл бұрын
We're glad it helped!! #KeepFocused
I pee about 15-20 times a day on most days. Sufffering from polyuria , not nocturia. Would this benefit me ?
@NursingEssentials
Жыл бұрын
Please note that the information provided in these videos is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
Plece telmi avaleble kerala
That medicine is expensive
Headache also side effects?
@jaime6567
2 жыл бұрын
headache is the only side effect on my ati book
so i'm having trouble understanding how desmopressin causes hyponatremia. I understand it increases the reabsorbtion of water in kidneys thereby decreasing urine output, so how i'm interpreting it is, i have a lot of water in my body (water follows solute), so there will be excess solute (hypernatremia) and not low solute(hyponatremia)
@NursingEssentials
5 жыл бұрын
This is an excellent question! Usually desmopressin is well tolerated, but sometimes hyponatremia can occur. One of the most common causes of hyponatremia occurs as a consequence of inappropriate prescription of DDAVP concurrent with hypotonic intravenous fluids. This combination is almost never appropriate, and under most circumstances the use of DDAVP and hypotonic fluids should be considered contra-indicated. Recall that water balance is achieved through regulation of ADH secretion from the hypothalamus through the action of osmoreceptors in the neurohypophysis (the posterior part of the pituitary) in which ADH secretion is suppressed during times of plasma hypotonicity and whose secretion is up-regulated as plasma tonicity increases. In the absence of ADH activity, water reabsorption from the urine across the medullary concentration gradient is not permitted and very dilute urine is excreted. When DDAVP is taken, urinary concentration is high and very little free water is excreted. Excessive water intake or administration of hypotonic fluids to a patient taking DDAVP can therefore lead to a reduction in the serum sodium, and ultimately if the situation is not corrected symptomatic hyponatremia may occur. Hyponatremic encephalopathy, the clinical manifestations of cerebral edema secondary to hyponatremia, can have a wide range of presentations. I hope this helps!
算命的不肯幫忙 她說兩百 但我只拿出了一百 他就跑掉了 又一直說女兒嫁美國的 色盲 我也很痛苦的 不知道 The fortune teller is not willing to help me to 算運勢 運途his daughter married an American but Color blind I am painful too I don't know
There is something wrong with you but you will never figure it out
Good vid sucks no one is watching it but I guess I can't take more than 3 not safe
@NursingEssentials
3 жыл бұрын
Thanks for watching!