Cyclic Acetal Protecting Group Reaction and Mechanism
leah4sci.com/acetal Presents: Cyclic Acetal Protecting Group Reaction and Mechanism in Organic Chemistry
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In this video:
[0:22] Acetal Protecting Groups Review
[1:54] Using the Gas Mask Trick
[2:52] Step by Step Analysis of Sample Problem
[6:27] Re-Draw Molecule
[9:14] Acid Catalyst Regeneration
This video shows you the detailed mechanism for forming cyclic acetal protecting groups! You'll also see tips about redrawing, and a time saving shortcut to use during practice and your upcoming exam!
Catch the entire Acetal Video Series along with the Acetal Practice Quiz and Cheat Sheet on my website at leah4sci.com/acetal
For more in-depth review on Acetals including practice problems and explanations, come join my online membership site the organic chemistry study hall: leah4sci.com/join
For private online tutoring visit my website: leah4sci.com/organic-chemistry
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Пікірлер: 74
I'm learning this right now in Orgo II. Perfect upload timing, thank you!!
@Leah4sci
6 жыл бұрын
That's awesome! glad to help
You are simply the best, LEAH. You made my organic chemistry 1 so easier and you still making the 2 as well. BRAVO! Keep up with the good work
@Leah4sci
5 жыл бұрын
Thanks Bernard! Always glad to help. :)
you might be my favorite person in the world. thank you so much for your amazing videos
@Leah4sci
5 жыл бұрын
Awww! thanks! and you are very much welcome! :)
Hey Leah, can you please make a couple of more videos in this series 1. regarding the protection of the ketone group in a compound where aldehyde and ketone both are present. 2. some complex practice questions. That'll be a lot of help. Thanks
@Leah4sci
8 ай бұрын
Thank you for the suggestions
Finally..some good teaching when I needed it... thanks
@Leah4sci
3 жыл бұрын
Glad it was helpful and you're welcome!
You just saved my homework grade. One of the best online science teachers with out a doubt
@Leah4sci
4 жыл бұрын
Thanks! Glad I could help!
This was so helpful, thank you!
@Leah4sci
4 жыл бұрын
You're so welcome!
Great video thanks! Just one question, my professor had the other alcohol on the diol attacking the electrophilic carbon center kicking off the water, whereas you had the oxygen resonate to kick off the water. Does it matter which way the water leaves? Again, Thanks!
@Leah4sci
5 жыл бұрын
I'm sorry, but I don't offer tutoring through KZread comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
GREAT VIDEO my question is if the diol used has the hydroxyl groups in the middle like butan-2,3-diol does the mechanism proceed the same as it did with the 1,2-ethandiol
@Leah4sci
3 жыл бұрын
Glad you like it! Yes, the mechanism would proceed in the exact same way. In your particular example, the only difference would be a couple of extra methyl groups present on your cyclic acetal. All electron-pushing arrows would follow the same pattern.
Only video of this mech I could find thx
@Leah4sci
Жыл бұрын
you're so welcome
One word - Excellent.
@Leah4sci
2 жыл бұрын
Thanks so much!
Very nice and helpful ,,,thanks a lot ❤❤❤❤
@Leah4sci
4 жыл бұрын
You're very welcome!
Best explanation...thanks..
@Leah4sci
6 жыл бұрын
You're very welcome
Thank you, Mam!
@Leah4sci
6 жыл бұрын
You're very welcome
Hi thank you for your help but in the formation of acetal from hemiacetal are you sure H2o+ won't leave on its own? because my professor didn't make the pi bond from lone pair on O and simply said this is an SN1 reaction and H2o+ is a good leaving group so it would leave on its own followed by a NA by the second alcohol.
@Leah4sci
2 жыл бұрын
I'm confident in my mechanism, but you should always know what your teacher wants you to draw. The water is a good leaving group, but rather than form a carbocation, I believe the preference would be to allow carbon to follow the octet rule and give the positive charge to oxygen.
@Czar_Char
Жыл бұрын
@@Leah4sci herh mbaaa
Thank you , ure explanation is very helpful mam😁😁
@Leah4sci
8 ай бұрын
You're very welcome!
Finally I got the answer for my MCAT question!
@Leah4sci
5 жыл бұрын
Glad the video helped!
Thank you!
@Leah4sci
5 жыл бұрын
You're welcome!
Thnku so much.. Respect for u from india
@Leah4sci
7 ай бұрын
You're very welcome
Thanks a lot, your videos are helping a looooot! I just have one question.. If we have a normal alcohol with only one OH group, the product is going to be with 2 O atoms that are not bonded with C atoms chain, and if we have an alcohol such as 1,4- diol with 2 OH groups, the 2 O atoms are going to be bonded with an C atoms chain (''monster''); am I right? TIA!
@aggelosharalabidis6915
6 жыл бұрын
you are right
@Leah4sci
5 жыл бұрын
I'm sorry, but I don't offer tutoring through KZread comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
@Czar_Char
Жыл бұрын
@@Leah4sci kmfd!!!!!!
Thank u so much!!
@Leah4sci
3 жыл бұрын
You're welcome!
I LOVE YOU THANKYOUUUU
@Leah4sci
3 жыл бұрын
You're welcome!
Thanks
@Leah4sci
Ай бұрын
You're very welcome
Very good
@Leah4sci
4 жыл бұрын
Glad you like it!
Thank u sooooo much
@Leah4sci
5 жыл бұрын
You're welcome!
@sugabear9511
5 жыл бұрын
Leah4sci omg!!!!! I can't believe u replied i love u so much u are my idol ❤❤
Am I the only one who sees a smiley face around the cyclic acetal protecting group @ 2:08, or am I just turning crazy?
@deepyaa3392
2 жыл бұрын
You aren't the only one
@Leah4sci
7 ай бұрын
Orgo makes you see things! Try looking at the budweiser logo without seeing a chair conformation 🤣🤣
HOW DO U REMOVE THE ACETAL
@Leah4sci
3 жыл бұрын
The acetal protecting group can be removed by the addition of acid in water. It would be an acid-catalyzed hydrolysis of the acetal.
Very nice mam
@Leah4sci
6 жыл бұрын
Thanks Muhammad
Great
@Leah4sci
6 жыл бұрын
thanks
Thanks mam
@Leah4sci
5 жыл бұрын
You're welcome :)
Thanks bae
@Leah4sci
4 жыл бұрын
You're welcome!
Methanamine r u mad it’s not that it is methylamine (a previous video)
@anjanibhardwaj7761
3 жыл бұрын
Hey it is methanamine as well ..... she's not mad
@Leah4sci
7 ай бұрын
I could be, who knows?
Ketones form ketals, not acetals.
@Leah4sci
2 жыл бұрын
According to current IUPAC rules, ketals are a subset of acetals. The term "acetal" encompasses both aldehyde-derived and ketone-derived structures.
Can you provide in hindi please I m from India 🇮🇳
@Leah4sci
4 жыл бұрын
Thanks for the suggestion, but this is something I do when I have extra time, so providing in Hindi isn't something I can do right now.