This is simultaneously the hottest track about a genome-editor, the best cover of Mr. Sandman, *and* one of the top 3 best genre fusions. Serious s-tier stuff here.

@ARBB1

6 жыл бұрын

And a acapella so good that at points I forgot there were no instruments

@camkaigon50bomb18

5 жыл бұрын

Typo it’s SSS tier

@kurtmooreca

4 жыл бұрын

You could say, he Crisr Cas9'd the fuck out of it.

@mrbaddin

3 жыл бұрын

S+++ tier if you want my opinion bud , bcs this is actually a big brain time song Ngl

@MikeTooleK9S

2 жыл бұрын

overwhelms me

I've been assigned the task of writing a CRISPR-Cas9 song for the youngest visitors at the museum where I work. Naturally I googled "CRISPR song" just to see if there was anything else out there. I'm handing in my letter of resignation tomorrow.

@guy3565

2 жыл бұрын

LMAO

@annesmith9642

2 жыл бұрын

Maybe Tim could help you.

@sebastianflavet2531

2 жыл бұрын

@@annesmith9642 I've actually just finished the song. Thankfully it's in Swedish, so nobody here will ever know just how awful it turned out. 🤣

@annesmith9642

3 ай бұрын

@@sebastianflavet2531 I'd love to hear it.

@sebastianflavet2531

3 ай бұрын

@@annesmith9642 kzread.info/dash/bejne/omupmc-xg7WxdNI.htmlsi=OKgSOJXlU69glvqy

"incite a scene" in place of cytosine is some amazing wordplay

@betapi1726

3 жыл бұрын

Rip guanine

@SimonClarkstone

2 жыл бұрын

"that one Nazarene" is a great turn of phrase too.

@violane_9557

Жыл бұрын

it really would in cytosine

@mameyn9282

4 ай бұрын

"Outside our power and inside us all" is also a great line

@Ath3nx_2

3 ай бұрын

@@betapi1726 and uracil lol (edit: i think those are the only bases used in both DNA and RNA; guanine is only dna and uracil is only rna)

This has got to be the nerdiest thing I've ever seen. I love it.

@toniborchert9934

4 жыл бұрын

i agree I. LOVE. IT.

@legendarycowboy4077

4 жыл бұрын

You stole my coment from my head

@thatchers_laboratory

3 жыл бұрын

This is the essence of my personality

@mhm6421

Жыл бұрын

i might as well reply when this somehow has 3 comments

Epic!

@IndianaSolo15

7 жыл бұрын

So epic! Hey Derek, you should come visit your Alma Mater, Queen's University sometime.

@valeriobertoncello1809

7 жыл бұрын

Veritasium WTF!

@twildawnight4341

7 жыл бұрын

That's the word ! !

@hamboning2402

7 жыл бұрын

Veritasium iq

@SKgames11

7 жыл бұрын

Veritasium 8

Now that the discovery of CRISPR-Cas9 has been awarded the Nobel Prize, this video should get revitalized and shared all over again!

@bostonseeker

7 ай бұрын

Tim should have been invited to the Nobel ceremony to perform for the King of Sweden. Command performance, dude!

I've only watched this 4 times so far. It hasn't been enough. I

@acapellascience

7 жыл бұрын

☺️☺️☺️

@hellspawn3200

7 жыл бұрын

only 4 times, i must have watched it like 40-50 times within the first 3 months, and by this post :P

@implementedideas1983

6 жыл бұрын

Physics Girl Let me remind you “I’m so alone”

@davutsauze8319

2 жыл бұрын

@@hellspawn3200 Hah, rookie numbers

@losfachmenn6365

11 ай бұрын

you should've dated terry davis

I first discovered this song when I was 13 or 14. Back then I had no bio knowledge, and basically only listened to this song for the epic harmonies. However many years later, I am now a college student learning about CRISPR in my gen ed bio class, so I came back to this song to see if I understood it any more. The result is me going wildly back and forth between understanding and being even more confused than I already was. A recreation of me watching this: "Encoding for a specific protein" - oh yeah, cuz the RNA guide's really easy to program, I bet it searches out specific sequences that make proteins, yeah this makes kind of sense "Make a few snips at this coded locus" - yeah yeah yeah i'm actually understanding this! "You work so well inside a streptococcus" - aaaaaand you lost me

@annesmith9642

Жыл бұрын

I'm sure you'll get there, Molly.

@AninditaRoy1

Жыл бұрын

Haha, you'll get there. The cas9 that was developed into the gene editing tool was from Streptococcus pyrogens and it works beautifully inside the bacteria to target and kill the bacteriophage trying to infect it.

@SCidejump

10 ай бұрын

All I know is streptococcus is a bacteria that causes strep

@military1325

10 ай бұрын

I'm 14 right now

@aurweon

7 ай бұрын

Afaik the theory behind how CRISPR works is based on observations of how the S. Pyogenes microbe does it naturally

This one just keeps modifying itself into something stronger. Poetic, that!

@ireallyhatemakingupnamesfo1758

7 жыл бұрын

acapellascience stop being so amazing, you make us mere mortals feel inadequate

@obeyerii1186

7 жыл бұрын

This is some good musix for mah ears and brain

@EdwardCree

7 жыл бұрын

In a way it reminds me of Tom Lehrer's _"Clementine"_. It's fun to try and identify the different musical styles as they go past.

@Koubles

7 жыл бұрын

Your vids keep getting better and better, but the better they get the longer i think your dead or cant afford to make videos anymore.

@acapellascience

7 жыл бұрын

+Kristopher Kohlmeier Au contraire, the more affordable this process becomes, the longer I take to do things right :P

You won me entirely with the Aladdin mash-up in 1:58. The thing is that not only the scientific part of the video is really well explained, but the artistic part is outstanding. ¡Olé!

@acapellascience

7 жыл бұрын

A call-ahead to a video I haven't made yet :P

@ricardosandoval7797

7 жыл бұрын

Crespo!!!!!!! :D

@dan200smx7

6 жыл бұрын

what aladdin song?

@ironsfamily6

6 жыл бұрын

Friend Like Me. Apparently is was a reference to the now released "Whole New Worlds"

@lorenzotagua6683

6 жыл бұрын

Crespo nos tienes que decir qué canales ves, que si son todos como este flipo!

my brain at 2am...

A student just sent me this song and oh my lordt the effort that must've gone into making this.... mindblowing I am IMPRESSED

This might be the best one you've made yet… and I'm not just saying that because I helped on it! :)

@nicocharm

7 жыл бұрын

When amazing people work together, amazing things happen.

@themashroomiatube6511

7 жыл бұрын

-ose

@hfyaer

5 жыл бұрын

Then ask for credit in the video description. I usually don't hate on youtubers, even propagandists, but you mate are the exception. You arrogance makes me cringe everytime.

@EgorTimatkov

5 жыл бұрын

@@hfyaer he is credited in the video description. It says there: JOE HANSON, right after --- End Screen Links --- which, by the way, brings up the fact that he is also credited at the end of the video, too. Verbally, in fact

@asc_near

4 жыл бұрын

@@hfyaer You can't judge people off their usernames man. He's got a channel that teaches science. He's not trying to act smarter than anyone else, it's just the name of a video series ran by PBS. Lol.

Holy cow, HOLY COW, it actually makes me mad to think about the fact that this video ONLY has 1.3 M views, with the insane amount of time and effort that went onto making it, from making the lyrics to recording every single little panel of the dozen that appear, it's crazy, Tim you're insanely talented. This video truly deserves at least 10 M views.

@liammarkey6933

2 жыл бұрын

Definitely

@annesmith9642

2 жыл бұрын

Just you wait.

@user-sx4kd8zn7m

Жыл бұрын

Very true

My best friend and I literally had this memorized in high school freshman biology and I’m back for the memories.

There should be awards for people like you.

I maybe only listened this about 280 times.

@emileblackwood8338

6 жыл бұрын

Relatable

@lazercatfilms8274

5 жыл бұрын

Ha I beat u Edit:281

@saoranachnah-alba723

4 жыл бұрын

Not enough

@asc_near

4 жыл бұрын

Only 280 times? Sheesh.

@idarkstarx6939

4 жыл бұрын

Those are rookie numbers, boy.

the first time I heard this was my freshman year of highschool. I am now 22 and this song gets stuck in my head on the regular. Absolutely love Acapellascience! Thank you!!

Fighting the urge to send this song to my science hating best friend who’s ex boyfriends name is Cas.

@Sora_di_Angelo

Ай бұрын

DO IT

@LoveSynapseheart

Ай бұрын

Don't 😂

@Ath3nx_2

20 күн бұрын

*_DO. IT._*

I watched this when it first came out, when I was still in high school, and I loved it but didn’t understand it at all. Now I’m a Neuroscience PhD student currently learning about CRISPR and I finally fully get it!! It’s been so fun to watch over the years of my science training 😄

@MarinaMontserrat

8 ай бұрын

Hi from Barcelona Corinne, congrats for your Neuro PhD🎉

@darkacadpresenceinblood

5 ай бұрын

so many comments like this and it's so wholesome😭 i'm in my first year of uni studying bio so i like, vaguely understand it but not all the small references. can't wait to finally fully understand it one day :D

Dayum man, you're unique

@phildenfer

7 жыл бұрын

Mad scientists unite ! Thanks DirtyBiology for bringing me here ! Make sure to check out his channel if you understand French !

@khenricx

7 жыл бұрын

Damn... Dirtybiology, Veritasium and It's Okay To be smart in the comment section, and I didn't know that video ? I feel so late x)

@drawsgaming7094

6 жыл бұрын

DirtyBiology is ~300,000 enough?

@pbz4994

6 жыл бұрын

salut dirty biology

@armeenghet9035

6 жыл бұрын

Tu devrais en faire la promotion sur ta chaîne pour les les francophones qui ne le connaîtraient pas ^_^ (ou alors tu l'as fait et j'ai pas capté) **well I was just sayin that he should present him in his french channel..

This is the theme song of today (7.10.2020) when _Emmanuelle Charpentierin_ and _Jennifer A. Doudnan_ got their Nobel prize in chemistry announced. Congrats for both of them!

@thoseradstars

11 ай бұрын

That is really awesome!!! What a perfect opportunity for it to be shared.

"With adenine and thymine incite a scene" - The background patterns A T and C! Also nice pun there

I just *love* the arrangement, lyrics and acapella aside The original to electro-swing, jazz to a full orchestra GAAHH I adore this

Why doesn't this have millions of views?

@Silverizael

7 жыл бұрын

I wonder that every day.

@monifernandez4245

5 жыл бұрын

Every day there are more persons ignoring more things..... Only a few understand and enjoy. Knowledge is elitizing

@danielsjohnson

4 жыл бұрын

It does now! :D

@alexandreamaral4362

4 жыл бұрын

It does now

@uxleumas

4 жыл бұрын

well, it has about 1 million now!

Some people wake up and choose violence. You woke up and chose masterpiece

Over three years later, this is still arguably The Best Thing on KZread.

@q-tuber7034

5 ай бұрын

Seven years in, still no contest

@Nothing-_-0024.

3 ай бұрын

@@q-tuber7034 no, there are some close competitors (evo-devo, the molecular shape of you, leukocyte, nanobot, entropic time) so basically... this guy is the GOAT :D

Three years ago I answered correctly a serial application exam (its a weird translation but it works) question because of this song, and that helped me to get into uni. Now, studying genetics, the crispr was mentioned, so im listening to this banger again

So normally the science parodies that Mister Teacher shows us in class are just a bit of fun that someone with a passion for science made but this one's a masterpiece and must have taken who-knows-how-long to make. So good that I went out of my way to go watch it outside of the classroom, very nice job!!

@annesmith9642

Жыл бұрын

I hope you brought it back in to share.

This song plays all day long in my mind since I first heard it each time we discuss genomic editing in my major XD

I come back to these virtuoso creations again and again. Really some of the best videos on KZread, they never get old.

@thanhnhano4853

2 ай бұрын

medlife with 2 likes??

Wow. This song has so many layers of information in it, that it's in a league of its own. I honestly don't know how this song doesn't have a billion views yet.

7 years later and I'm back to realize: this still might best the best music video on youtube (myy opinion)

"adenine and thymine incite a scene" I see whAT you did there, younG mUsiCian.

@danieltigas9771

4 жыл бұрын

I don’t understand it

@kevinaugustsson2202

4 жыл бұрын

@@danieltigas9771 incite a scene sound like "and cytosine" which is another nucleotide base

@acetuberjason6730

4 жыл бұрын

Wasn’t it thymine? Edit: It was “Adenine and Thymine”. I checked the lyrics. Edit 2: “Incite a scene” is supposed to be “and cytosine”. I’m an idiot.

@kevinaugustsson2202

4 жыл бұрын

@@acetuberjason6730 there are 4 bases, in RNA uracil replaces thymine

@acetuberjason6730

4 жыл бұрын

@@kevinaugustsson2202 Ok thanks

In case you don't want to use the link, here's the lyrics: CRISPR-Cas9 Bring me a gene Encoding for a specific protein Make a few snips at this coded locus You work so well inside a streptococcus Cas9 I'm so alone Without your scissors in my chromosome Cut me up and do it clean CRISPR-Cas9 bring me a gene CRISPR-Cas9 Keep me a gene A viral sequence you've already seen Chopped into bits and stored as genomic With clustered repeats That are palindromic Cas9 Bind with this code Use it to target infections of old Immunized like a vaccine CRISPR-Cas9 keep me a gene CRISPR-Cas9 Cut me a gene With a precision that I've never seen Unzip a strand and interrogate it Seek out your sequence until you locate it Cas9 Lock into place And do your job as endonuclease Chop just like a guillotine CRISPR-Cas9 cut me a gene Snip snap! CRISPR-Cas9 CRISPR-Cas9 CRISPR-Cas9 Bring me a gene By commandeering my repair routine A strand to match your severed location For some homologous recombination Cas9 Cheap and precise Rewriting genomes from microbes to mice And soon the humble human being CRISPR-Cas9 bring me a gene CRISPR-Cas9 Give us a gene Give us a miracle like that one Nazarene ‘Cause giving the lame their legs and the blind their sight is In view for dystrophy and retinitis But CRISPR-Cas9 What if you fall Outside our power and inside us all That really could incite a scene When this terrible wonderful power unsettling Opens the door to unethically meddle Is ev’ry congenital malady bettered Sufficient to warrant genetics unfettered To modify man in the manner of Gattaca Raise up a mammoth or make a rattata Dramatical medical means to eradicate aging Or cancer or make a fanatic A mass epidemic a weapon nefarious Single mosquito to wipe out malaria Send in a viral infection to ferry a Cure to the cells of an HIV carrier Freed of disease as we're free to uncover What nature and accident failed to discover And free to be other than All that we ever have been CRISPR-Cas9 CRISPR-Cas9 Oh CRISPR-Cas9 Bring us a gene You wondrous ribonucleoprotein You have the power to vanquish or save us Who would have thought that the microbe that gave us Cas9 S. pyogenes The source of strep and flesh-eating disease Housed this marvellous machine Full of uses great and obscene CRISPR-Cas9 bring us Please don't sting us Cas9 bring us a gene With adenine And thiamine Incite a scene Cas9 bring us a gene!

@alegarza

7 жыл бұрын

zelda64rules thank you, kind cyber citizen

@zelda64rules

7 жыл бұрын

You're welcome.

@Quintinohthree

6 жыл бұрын

zelda64rules Relevant nitpick: third to last line is "and thymine" not "and thiamine" they are very different compounds and although their pronunciation might be similar they should be distinct.

@Quintinohthree

2 жыл бұрын

@@charliegoodwin8651 Nope, but you got the joke so you get half points anyway.

@Nothing-_-0024.

3 ай бұрын

no way, you are amazing thank you

Not gonna lie, this is by far the best video on the internet when it comes to explaining the CRISPR/Cas system. It explains everything in a catchy hot manner. even future possibilities and ethical problems.

This video was a complete knockout!! I showed it to my friend PAM but she thought it was a bit off-target.

@jpvieira3998

6 жыл бұрын

I want to "like" your comment two times... maybe more. lol

@ICKessler

6 жыл бұрын

I saw what you did there. :D

4 years and a Nobel later, still amazing !

HE RHYMED "AND CYTOSINE" WITH "INCITE A SCENE" PURE GENIUS

I think I've watched this like 10 times now and I'm still bewildered at how accurate and super entertaining this is.

WHAOOOOOOO I just smiled throughout this whole thing. SO COOL!!

@R.Instro

7 жыл бұрын

This comment smells like knowledge.

@RQLexi

7 жыл бұрын

R.Instro That's probably because it still has brains on it.

@R.Instro

7 жыл бұрын

Alexis Rainbow Queen Ahhh, that would explain it. ^_~

OMG THIS IS THE MOST AWESOME THING I'VE EVER SEEN!!!! *BRAAAAAAAAAVOOOOOOOOOOOOOOOOOO* Seriously, that 2:58 part is absolutely SUPERHUMAN

@implementedideas1983

6 жыл бұрын

CoriSparks the only part of the sing I cannot learn

@theplanetmercury7487

5 жыл бұрын

It carries the sounds of "help, my computer died."

Holy crap, your videos are all scientifically and lyrically and musically impressive, and this one is all those things, but the musical arrangement in this one particularly stands out! Absolutely incredible work, I can't get enough of it. Thank you for making these, I'm breaking into writing science parodies myself (medical, specifically) and you're a huge inspiration!

Made especially for nerds and geeks like me. This man has so much talent. Thank you for inventing this.

Wow that was delicious on so many levels. Well done man, you are an amazing entertainerd.

@acapellascience

7 жыл бұрын

Thanks man! I definitely owe you for prompting me to understand barbershop.

@CaptainWolff

7 жыл бұрын

The barbershop part was beautiful! I wish you would have done the whole song in that style in stead of the more common beat-box a capella style.

@onixtv4034

4 жыл бұрын

You missed an e, JK.

@mariadelnaja480

4 жыл бұрын

Ooooh of COURSE you've seen each other's videos. You're both stellar musicians! Small internet world, right? Consider a collaboration?

Wow that was MENTAL ! I can't begin to imagine the amount of work put into this... Brilliant job ! :) I'm really glad you mentionned the ethical part of it as well, at some point around the middle of the song I was worried this would be a complete promotion of gene editing without any warning !... Nicely done, keep up the good work !

@Fatortu

7 жыл бұрын

I was confident the ethical aspect would come up. Eminemium is pretty preachy^^

@SuperRosel

7 жыл бұрын

Responsability comes once you're a science guy, yo !

@MetFanMac

7 жыл бұрын

I'm glad Gattaca got mentioned too, a few seconds after I thought of it ^_^

@elliejf

6 жыл бұрын

Luckily for you, you don't need to imagine it! Go to acapellascience2 to watch the making of it!

Guys, help me out. How do I say "It's 3am and I'm lying in my bed almost crying because I love science and I love a capella harmony and this is the best thing I've ever seen and you are so so talented and amazing and I would also perhaps maybe like to marry you, hi" in the least creepy, preferably at least semi-normal, and most decent way possible? I'm a linguistics major but right now I'm at a loss for words. I think my brain inadvertently just turned into mashed potatoes.

@acapellascience

7 жыл бұрын

There's no non-creepy way to do that. But if you like linguistics, I highly recommend Tom Scott: kzread.info/dash/bejne/ZKWImrySldq_dbw.html

@xyz7572

7 жыл бұрын

acapellascience oh my goodness, I didn't think you'd actually see my comment. I- sorry. Honestly, sorry. I was just really tired and fangirling about science and over how amazing your videos are, I found your channel just two days ago. Again, sorry. Now that I reread that comment in the morning I do agree that it does sound extremely creepy. What I meant to say was, you're very talented, keep up the good work. Science is awesome. Sorry. /facepalms and digs a hole in the ground to live in forever because I can never face anyone ever again/

@MissWeerdo

7 жыл бұрын

acapellascience Haha I've seen worse comments, don't worry, I think Jozie is just a huge fan :) You are hella talented, dude :)

@acapellascience

7 жыл бұрын

Jozie Charles Haha I'm so sorry! :) That was meant to be playful but I don't think it came across. I forgot that inflections don't come across in text form. Really, I'm not creeped out at all! Just glad to have a fan. Cheers!

@acapellascience

7 жыл бұрын

I'm always jokingly deadpan in real life; I have to remember that if you don't actually know me it probably just comes off mean. #sorry

"With adenine and thymine *n' cytosine* " You are just the best, and I love you

The amount of editing that went into this is mindblowing...

this is definitely my favorite version of this song hands down - and this is my favorite song to begin with.

Best version of this song I've ever heard

Oh my lord, this changed my life. We are your biggest fans. Please continue with your sensational work! This was so fantastic. From Lynbrook High School's Period 4 Science Research Class.

@acapellascience

7 жыл бұрын

Sam Cohen Glad to be of use!

this aged well lol

You hoping for CRISPR to win the Nobel so you could release this during the announcement, weren't you? Oh well...

@acapellascience

7 жыл бұрын

That would have been nice, I'll admit.. But no, this was just the best idea I had so I made it :P

@TheBatmannotBruceWayne

7 жыл бұрын

When I work in the Doudna lab, I will show this to her because this was absolutely terrific!!!

@TheRealHiboman

7 жыл бұрын

The Batman Are you actually going to be working in the Doudna lab?

@TheBatmannotBruceWayne

7 жыл бұрын

I REALLY HOPE SO AND I THINK I HAVE A PRETTY GOOD SHOT AT IT!! I'm an undergrad at Cal and she taught Bio 1A last semester, so, normally, I fangirled and went to office hours regularly and still do now that I'm in the second half of the Bio series.. I asked her what bio/chem classes undergrads in her lab complete before beginning to work in her lab and I mentioned I was interested, so by the end of this semester I'll have an answer because I'll be done with both sequences. She signed my notebook and we even took a selfie!!

@TheRealHiboman

7 жыл бұрын

The Batman HOLY CRAP that is amazing. I get to see her speak later this month and I'm also fan-girling super hard. She's a superstar

Am I only one that this song gives “theme for positively crazy, lovable and powerful character that eventually becomes the most dangerous antagonist” vibe?

I worked my ass off for 4 months to assemble Cas9-RNPs in-vivo but the dear Mr. Cas9 just wouldn't perform as asked. Thank you for lightening my mood and keeping the entire lab motivated :)

"You have the power to vanquish or save us." Subtle Harry Potter reference!

This is actually one of the best put together science song I've ever heard!

Seven years and this bop still lives in my head rent free, and I still return to it every now and again. Love your work!

I found this song just yesterday, I take it as a sign. Let's celebrate the Nobel🥂

As a biochemist and a musician, you took my heart and made me laugh like a baby. My most sincere gratitude.

_When you're beginning to feel like a Rap God and a Rap Scientist at the same time:_ 2:58 - 3:22

This is a masterpiece of a really professional niveau. For creating this as a single person deserves all my respect!

This one is so dense in references, musical jokes, scientific insiders and other witty shenanigans that Im concerned we'll have a singularity here...

Why. Can’t. I. Like. This. Masterpiece. More. Than. Once?!

An appropriately epic song for an epic scientific breakthrough :D Brilliant as always!

This has been stuck in my head all day! I have been singing it to my lab friends! Thank you so much for writing this and for all the work you put in to put into making this video!

This hits so damn hard... not only is it incredibly informational but it's also just musically magnificent.

You know I imagine the editing of human genes came faster than you expected.

I must have watched this hundreds of time already and never noticed that you hold up scissors at 0:32. How did I miss that?

Most underrated KZread content. Keep up the good work!

The Nobel prize award 2020 in chemistry brought me back here!

This song is hotter than ever in 2020! It would be the perfect song played at the Nobelprize Award Ceremony, honouring Emmanuelle Charpentier and Jennifer A. Doudna for the discovery of CRISPR-Cas9. 😍

Well. Time to rewatch this one for ... current reasons.

My 9 year old won't go to sleep without watching one of your videos, and he especially loves this song and Molecular Shape of You. It amazing how talented you are to make such incredible songs.

WOAAAH! I heard the audio preview version of this and loved it, but being hearing-impaired I couldn't appreciate the full magical beauty of it. Now I've seen the video (and the accompanying subtitled lyrics, yay!) I can unleash my full-on awe. Spectacular job!

Absolutely incredible as always. Still can't understand why your channel hasn't blown up more.

Still to this day this is one of the most underrated videos.

I... there are no words. I mean, I've seen some good stuff on KZread and some of it was on your channel(s), but that.... that actually made me tear up. My jaw was on the floor and salt water was coming out of my eyeballs. Dare I say that was better than bohemian gravity. And let it me known that I have memorized that song and sing it at work. I just... wow dude. Props to you. Well done sir, well done.

@aav56

Жыл бұрын

You seem like you have many words.

@thoseradstars

11 ай бұрын

I tear up also when I get about halfway through. It’s a combo of my passion for musicianship / vocalizing (many forms) and my passion for medical biology, as well as probably also my autism.

All the more significant, considering Wednesday's announcement about this year's Nobel Prize in chemistry.

Ok, this is way beyond nice. This is ridiculous... This is brilliant musically, textually and graphically (Art Deco Voronoi, anyone?). Also the molecular shape of you contains some of the best explanatory animations of electron clouds I've seen to date. Extremey well done! I'm eagerly awaiting your next project and well on my way through your portfolio enjoying myself immensely. I would be mortified of making a mistake, if I were you, but given the detail and the broad knowledge displayed I guess there is a team behind this for fact checking? Cudo's to all.. Way to make nerdy science cool and even mainstream.

I still come to this video every once and awhile. I really think this is one the best ones you've ever done!!

Hell's bells, that's a lot of Tims! It's so evident that an enormous amount of work and talent goes into these! Well done.

This song assisted my through my whole studies, from bachelor til masters now :) Chapeau!

That was awesome, I can't stop talking about your channel to other science geeks. Man, you deserve success.

The sheer depth and intensity of production here is incredible. You've earned yourself a subscriber today!

This is a masterpiece. It deserves so many more views. Loved it!

You really nailed it! Fantastic job

Now it gained a Nobel Prize. Epic!!!

every time I come back and rewatch this I'm incredibly impressed all over again

These get more and more amazing every time a new one comes out. Well done. It gave me chills.

My high school teacher showed this video when he was explaining Crispr yesterday lolol awesome video, dude

Love these videos ! they always brighten up my mood when i'm feeling depressed. keep up the good work.

oh my god, i get freaking CHILLS at the part that starts at 2:30

I have been replaying this for like an hour now.. Such a great song!

It's so well made, such an amazing work, I totally loved it

Since hearing this tune all these years ago I can't read a news about CRISPR Cas9 without singing it in my head... Since it was all over the news the last few days (Nobel hype), I had to watch it again. Still genius

i know its now almost 2 years old and hasnt as much views as the rest of your videos, but i still think this is the best video you made so far. they way the lyrics correspond with the music and evolve and recombine and escalate is pure art!

this has got to be my favourite out of your videos!!

Watching this again after the Leukocyte video just dropped and it still just leaves my jaw on the floor. Holy shit, man. What. A. Song.