Chromosomal Deletion, Inversion, Duplication and Translocation

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Пікірлер: 170

  • @lesahanners5057
    @lesahanners50576 жыл бұрын

    Just found your lecture. My son had extra material on the distal arm of his 11th chromosome. They called it 11q+ syndrome, for lack of a better term. In the 23 years that he lived I was never given any explanation about what that meant or any positive prognosis on how he would develop. Tho I and my husband were not exposed to radiation in our environment, we were both exposed to high lead levels, and he in his work place, to trichlorethylene and other industrial solvents, which he brought home on his clothes. Your lecture has done more to explain the several possibly actions of chromosome's than all the doctors I had my son to in the 23 years of his life. I thank you, even tho he is now deceased, for clarifying in my mind his chromosomal anomaly and the mechanics of how he received it.

  • @dampalranawaka7040

    @dampalranawaka7040

    6 жыл бұрын

    Lesa Hanners i'am very sorry for your loss😔😔

  • @hazim9529

    @hazim9529

    3 жыл бұрын

    Surprise mechanics.

  • @markyaus2011

    @markyaus2011

    3 жыл бұрын

    Hi Lesa, So sorry for your loss. I have a 5 year old son with a Micro-Duplication on his 5p13 and 8q11 chromosomes, and he presents with mild Autistic-like symptoms and Apraxia - he can’t talk yet, just babbles. Although, he seems happy and is affectionate. It’s so sad, and we don’t have any about his Prognosis because all the Doctors and Geneticists we’ve seen are near-useless! Every answer to any of our questions is: “Oh well, Yes & No”; or “Possibly”; or “We don’t really know...who can say?” I’m was concerned hearing about your Son who tragically passed at 23... my Wife & I have never been told of any shorter Life Expectancy for our Son...? He’s is perfect health. Do you mind if I ask you if his passing was attributed in any way to his Micro-Duplication? Thank You so much for your help 🙏

  • @lesahanners5057

    @lesahanners5057

    3 жыл бұрын

    @@markyaus2011 Only in the sense that it left him very vulnerable to colds, flu's, and pneumonia. He died of H1N1-A in 2009. His heart and lungs simply could not handle the severe form of this flu.

  • @user-pr2uf4ck9e

    @user-pr2uf4ck9e

    2 жыл бұрын

    @@markyaus2011 didn't u get in pregrancy?? Was ur baby iugr in third trimester??? Wat was birth weight

  • @missluciagray9753
    @missluciagray97532 жыл бұрын

    I cannot really express how thankful I am for this lecture of yours. I have a report regarding this tomorrow and I was really on the edge of breaking down when I saw this video of yours. Thank you very much.

  • @Owmed
    @Owmed8 жыл бұрын

    You're a such a good teacher!! Keep up the good work, greetings from Brazil!

  • @unsealedrex3446
    @unsealedrex34468 жыл бұрын

    I understand when I watch your lectures. They're empowering. Thank you.

  • @angelikakreling
    @angelikakreling4 жыл бұрын

    You have helped me through undergrad, studying for the MCAT, and now medical school. Your videos and explanations are amazing. I just want to say thank you!

  • @ph1lodox361

    @ph1lodox361

    3 жыл бұрын

    You take this in medical school?

  • @angelikakreling

    @angelikakreling

    3 жыл бұрын

    @@ph1lodox361 Unfortunately, yes.

  • @ph1lodox361

    @ph1lodox361

    3 жыл бұрын

    @@angelikakreling im studying this and im 16 years old!

  • @angelikakreling

    @angelikakreling

    3 жыл бұрын

    @@ph1lodox361 yeah we obviously learn this before med school but we forget it. This a review in med school. Just like the kreb cycle, some things you learn it 50x in school and still have to relearn it.

  • @ph1lodox361

    @ph1lodox361

    2 жыл бұрын

    @Sejoon Jun ok "bro"

  • @Lena-nl2on
    @Lena-nl2on8 жыл бұрын

    Clear and right to the point, really helped me a lot! Keep it going

  • @zauberzwerkpaul2605
    @zauberzwerkpaul26058 жыл бұрын

    thank you so much...i would be lost without you !

  • @StereoSoundAgent
    @StereoSoundAgent6 жыл бұрын

    fantastic content, and 100% applicable to the chapter I'm studying on "Large-scale chromosome changes." I give you credit for being a much more focused person than I am.

  • @sergiojamir1299
    @sergiojamir12995 жыл бұрын

    Made things simple and Understandable with his lecture. Would recommend it to everyone.

  • @KittieKitten92
    @KittieKitten927 жыл бұрын

    You're amazing! love your channel, im learning from it to my genetics exam! Greetings from Buenos Aires-Argentina

  • @60.syedasumaiyahmusannaali21
    @60.syedasumaiyahmusannaali212 жыл бұрын

    I had no idea this could be explained this easily! Thankyou so much!

  • @jedalynquintar8563
    @jedalynquintar85635 жыл бұрын

    Everything was clearly explained in the most detailed manner 👏

  • @patriotalgerien
    @patriotalgerien6 жыл бұрын

    We have our courses in French but honestly this video helped a lot THANK U SOOO MUCH 🙏

  • @hleketanikhubayi7790
    @hleketanikhubayi77902 жыл бұрын

    oh wow , you such a good teacher considering that i am a visual student i will never forget this , thank you so much.

  • @supersweetnisa
    @supersweetnisa4 жыл бұрын

    you are the reason i understand biology. thank you sooooooo much

  • @abigailjacob7892
    @abigailjacob78925 жыл бұрын

    Thank you for this very clear and understandable explanation!

  • @abdullahcan6950
    @abdullahcan69507 жыл бұрын

    Your lectures are amazing! Thank you

  • @samanthabaker2490
    @samanthabaker24905 ай бұрын

    This is so incredibly helpful! Thank you

  • @Joytresh
    @Joytresh3 жыл бұрын

    Thanks a lot I really appreciate this lecture, I understood everything perfectly well.

  • @noufalotaibi5848
    @noufalotaibi58482 жыл бұрын

    really no words can explain how amazing are your videos

  • @hannacortez1111
    @hannacortez11115 жыл бұрын

    Thank you, you explained this so well

  • @jasminegozun3337
    @jasminegozun33375 жыл бұрын

    This video is truly helpful!

  • @carlwilliams8425
    @carlwilliams84258 жыл бұрын

    Just WOW...Thank you so much!!!

  • @IsmailKhan-qt2xz
    @IsmailKhan-qt2xz8 жыл бұрын

    Great ! Made it a lot easier. Thanks

  • @mmaking8664
    @mmaking86648 жыл бұрын

    EXCELLENT EXPLANATION!!!!

  • @ebtihalahmed2289
    @ebtihalahmed22898 жыл бұрын

    That was so helpful. Thank You

  • @zero450571
    @zero4505718 жыл бұрын

    another great video, thank you very much

  • @vruttoh
    @vruttoh7 жыл бұрын

    Nice lecture. I'd love to see one that delves more into FISH and Nomenclature.

  • @siddhantjain8310
    @siddhantjain8310 Жыл бұрын

    Best video...just watched 20 mins before my University exam

  • @ToshaNLPN
    @ToshaNLPN10 ай бұрын

    Thanks for the video! Very helpful

  • @jigyasasharma4849
    @jigyasasharma48494 жыл бұрын

    Thank you, sir, for this lecture, it really helped me.🙌

  • @cartoonjunior2672
    @cartoonjunior26723 жыл бұрын

    amazing teacher ❤️ following from Egypt

  • @a.k.s3805
    @a.k.s380510 ай бұрын

    Thank you so much! This really helped me alot!!

  • @saraj233
    @saraj2338 жыл бұрын

    Thank you so very much!!!

  • @mohanady
    @mohanady9 жыл бұрын

    thank you very much. this indeed will help me on my mrcpch exam

  • @kaylisousa9464
    @kaylisousa9464 Жыл бұрын

    thanks so much, really helped!

  • @kennethringo9137
    @kennethringo91373 жыл бұрын

    Thank you. It helped ease my doubts.

  • @hanan72
    @hanan725 жыл бұрын

    A great explanation 👍🏼

  • @safnasagar2236
    @safnasagar22363 жыл бұрын

    This really helped 😊❤️ thank you so much 💕

  • @alexanderdamkr5171
    @alexanderdamkr51716 жыл бұрын

    Best teacher!

  • @jasminc.7731
    @jasminc.77315 жыл бұрын

    A great explanation, it is vert helpful for us students.

  • @hichemkickboxer
    @hichemkickboxer7 жыл бұрын

    thank you so much ! very useful

  • @azadekiani5479
    @azadekiani5479 Жыл бұрын

    Amazing! Thank you

  • @debosmitachakraborty2445
    @debosmitachakraborty24453 жыл бұрын

    Now I got it.. thanks teacher 🙏

  • @abidhasan8888
    @abidhasan88883 жыл бұрын

    I'm from Bangladesh....this channel is really very helpful....

  • @DeeqMohamed-yl7te

    @DeeqMohamed-yl7te

    3 жыл бұрын

    Me too I am from somalia this channel is very important

  • @valersodmarvin5975
    @valersodmarvin59755 жыл бұрын

    👏Great explanation👏

  • @hooralr6329
    @hooralr6329 Жыл бұрын

    Helped me a lot thank you

  • @yugen3987
    @yugen39877 жыл бұрын

    شكراً لك :)

  • @MonkeyDLuffy-xr4fl
    @MonkeyDLuffy-xr4fl8 жыл бұрын

    Thank you!

  • @amanim2503
    @amanim2503 Жыл бұрын

    wow u simplified it thx!

  • @mariatagliavento9351
    @mariatagliavento93516 жыл бұрын

    My problem solved,,,excellent lecture

  • @eyesnehasingh
    @eyesnehasingh Жыл бұрын

    Thankyou Sir This video helped me a lot.

  • @dayangsuhana5531
    @dayangsuhana55317 жыл бұрын

    thank u so much! its really helpful :)

  • @aisyarz7734
    @aisyarz77344 жыл бұрын

    Very helpfulll..a big thumbs up to this vid

  • @Sunshine-zi7oy
    @Sunshine-zi7oy Жыл бұрын

    no one can put it at point like you do sir

  • @mohammedal-hammadi5085
    @mohammedal-hammadi50854 жыл бұрын

    You are great!

  • @ahealingplace7350
    @ahealingplace73503 жыл бұрын

    I'm in awe 😳😳. Don't mean to bash my lecturer....but he confused me and did not explain this topic well... when I heard your explanation I was so grateful for the clear and concise explanation!!!! Thank you❤❤

  • @tariqueusmanimohd7213
    @tariqueusmanimohd72135 жыл бұрын

    Thanku sooo muchh good explanation.👌👌

  • @ayarstart9740
    @ayarstart97408 жыл бұрын

    Amazing thanks alot ...

  • @lovelyyarora6207
    @lovelyyarora62078 жыл бұрын

    very helpful :) thanks !

  • @Ímiah16
    @Ímiah16 Жыл бұрын

    Thank you very much👍🏻👍🏻👍🏻

  • @borodelove
    @borodelove3 жыл бұрын

    Thank you!!

  • @nurseliez87
    @nurseliez874 жыл бұрын

    Thank you so much.

  • @shannonlmace5227
    @shannonlmace52279 жыл бұрын

    This video was really helpful! Your explanation was clear and very easy to follow. The only problem I had was with the volume. Thanks so much though!

  • @AKLECTURES

    @AKLECTURES

    9 жыл бұрын

    Shannon Mace Sorry about the volume Shannon, I did not realize the mic volume was not calibrated at the time of recording! Luckily I realized pretty quickly (only after several lectures) :)

  • @dominic2446

    @dominic2446

    5 жыл бұрын

    (i also feel that) the volume is too soft.

  • @mahijamal8179
    @mahijamal81792 жыл бұрын

    Hi sir I am from Pakistan your lecture is very helpful for us bundle of thanks sir

  • @zas881
    @zas8812 жыл бұрын

    Thank you very much

  • @Dr.JM1
    @Dr.JM14 жыл бұрын

    Good job, thank you! I would like to ask you, do you know how these mutations could be seen in the PCR technique?

  • @marimendez1188
    @marimendez1188 Жыл бұрын

    Thanks for the video! I'm curious if there's a particular phase in the cell cycle where translation can occur or can it be during any phase of the cell cycle?

  • @hassank408
    @hassank4088 жыл бұрын

    Thanks a lot for this amazing and clear explanation. My question is during exposure to radiation, are all cells affected or, single or group of cells?

  • @Jana-2004
    @Jana-20047 ай бұрын

    Thank you soooo much 😢

  • @BlacFireSan
    @BlacFireSan9 ай бұрын

    Thanks mate

  • @junczhang
    @junczhang8 жыл бұрын

    thanks!

  • @Serein.original203
    @Serein.original2032 жыл бұрын

    Thank you 😭😭

  • @generationalmodal1531
    @generationalmodal1531 Жыл бұрын

    Well explained

  • @bibhashranjannath4855
    @bibhashranjannath48554 жыл бұрын

    Love from INDIA sir

  • @geirfammestaddonski4835
    @geirfammestaddonski48353 жыл бұрын

    Thank you! You made it fun to follow along 🤓 So with a translocation, will the segment that breaks off attach at the corresponding sequence of the new chromosome?

  • @neetusrivastava1521
    @neetusrivastava15214 жыл бұрын

    Thanks sir.

  • @azadekiani5479
    @azadekiani5479 Жыл бұрын

    It would be great if you will make more videos about human diseases and explain their mechanisms and effects on body from a biochemistry point of view

  • @siyabendunus6443
    @siyabendunus64434 жыл бұрын

    thank u!

  • @qayxsw5900
    @qayxsw59005 жыл бұрын

    Thank you

  • @sanchalikabasu2446
    @sanchalikabasu24469 жыл бұрын

    Thank u...

  • @aqk5964
    @aqk59644 жыл бұрын

    God bless you

  • @sudharaninalluri1961
    @sudharaninalluri19614 жыл бұрын

    Super explanation sir

  • @Rafah280
    @Rafah2808 жыл бұрын

    thinks a lot

  • @diegoeloyrnavarrolopez7555
    @diegoeloyrnavarrolopez75553 жыл бұрын

    Excelent!!!! :) thanks!!

  • @SheliTwinsMom
    @SheliTwinsMom7 жыл бұрын

    clear concept

  • @ashiskumarhial4083
    @ashiskumarhial40835 жыл бұрын

    Thank you sir

  • @Midhun_Rajan
    @Midhun_Rajan6 жыл бұрын

    Thanks

  • @bando456
    @bando4566 жыл бұрын

    bruh this is pretty good

  • @user-wp2ne1uy6j
    @user-wp2ne1uy6j5 жыл бұрын

    Veryyyyyy GOOD explanation

  • @kobeamansoni7613
    @kobeamansoni76133 жыл бұрын

    good lecturer

  • @beatricecolombo5475
    @beatricecolombo54756 жыл бұрын

    Man! You are an amazing teacher! I have a question: does the duplication occur just in this way? Is it possible that a gene duplicates bc of an error of the DNApol? I mean, is it possibile that 2 homologous both have the gene and in one there is also an extra copy that doesnt derive from the homologous but from an error in duplication?

  • @ashleylong3903
    @ashleylong39038 жыл бұрын

    Awesome job!

  • @AKLECTURES

    @AKLECTURES

    8 жыл бұрын

    +Ashley Long Thanks Ashley!

  • @The_Wild_CaNaDa04
    @The_Wild_CaNaDa04 Жыл бұрын

    Andrey K respect

  • @munircelebi8127
    @munircelebi8127 Жыл бұрын

    👍🏻 great

  • @gorabsingh7277
    @gorabsingh72774 жыл бұрын

    Nice thanks

  • @caderlocke8869
    @caderlocke88698 жыл бұрын

    You have a genetics channel too?!! Why did I even bother enrolling in such courses.

  • @AKLECTURES

    @AKLECTURES

    8 жыл бұрын

    +Cader Locke lol! the more, the merrier! check out my website for a complete list of subjects! :)

  • @AKLECTURES

    @AKLECTURES

    7 жыл бұрын

    ***** love it!

  • @azizsamawi4727

    @azizsamawi4727

    5 жыл бұрын

    Raeda

  • @Stories_4_Everyone
    @Stories_4_Everyone8 жыл бұрын

    Do you have any videos about Paracentric inversions? Thank you.

  • @stormsheep1722
    @stormsheep17224 жыл бұрын

    very goooood

  • @MMA_BEASTHUB
    @MMA_BEASTHUB3 жыл бұрын

    Nice now I can skip more classes in college