Celiac Disease | Clinical Presentation

What is Celiac disease? Celiac disease, sometimes called celiac sprue, is a condition where the immune system reacts to gliadin, a component of gluten, which is found in various grains like wheat, barley, and rye. This video covers the known pathophysiology, as well as important clinical signs and symptoms

Пікірлер: 69

  • @DrAdnan
    @DrAdnan4 жыл бұрын

    Osmosis is one of my favorite study video resources!

  • @m.b4004
    @m.b40043 жыл бұрын

    Tbh,this one is Better than the 2021 edition

  • @user-mr3iv7bj6n
    @user-mr3iv7bj6n Жыл бұрын

    keep going on , awesome video❤

  • @tamanarawan8401
    @tamanarawan8401 Жыл бұрын

    Thanks alot , you made it soo clear .

  • @draanapimenta4124
    @draanapimenta41243 жыл бұрын

    First time seeing this film! It seems like I am drawing to explain the disease to my celiac patients or their relatives! Thanks! a good link to send to them!

  • @baraadaod8749

    @baraadaod8749

    Жыл бұрын

    Can you pls help me with my question

  • @lakshayrana3719
    @lakshayrana37193 жыл бұрын

    Explained in an awesome manner but the video is a bit blurred and hazy

  • @nikitachaudhary6548
    @nikitachaudhary6548 Жыл бұрын

    Very nice explanation

  • @francescopentangelo7943
    @francescopentangelo79439 ай бұрын

    you bro, you are a so good boy. thanks for that video

  • @zack_120
    @zack_120 Жыл бұрын

    0:50 - the endosperm part comprises largely starch and some proteins, not vitamins and minerals which are mostly in the bran layer that encloses the endosperm and germ. This is why eating whole grains is being promoted.

  • @jakaullahshekh7539
    @jakaullahshekh753911 ай бұрын

    very informative

  • @bootatoboo
    @bootatoboo Жыл бұрын

    celiac disease is also a common cause of iron deficiency anemia, i was hoping to find out the mechanism but im guessing the destruction of enterocytes containing transferrin receptor (due to cytokines released from T-cells) causes there to be less TSR hence decreasing the absorption of iron. if im wrong please correct me.

  • @yolo_39

    @yolo_39

    7 ай бұрын

    Which college are you in?

  • @ganeshphad1432

    @ganeshphad1432

    7 ай бұрын

    But what's the solution for this 🤔

  • @ilijanarancic7722

    @ilijanarancic7722

    5 ай бұрын

    That's the mechanism, the destroyed duodenal mucous membrane can not absorb iron.

  • @salahelsherbini2748
    @salahelsherbini274825 күн бұрын

    This was so good.

  • @leavesofchange
    @leavesofchange Жыл бұрын

    Would the mechanism work exactly the same if you substituted secalin for gliadin?

  • @717JHT
    @717JHT14 күн бұрын

    I do have muscle related symptoms when I have gluten crosscontamination, you said in your video that there is no symptoms, but I do have them, within minutes of ingestion, I don’t know how to describe it, but it seems that my entire skin and muscles start feeling heavy as lead, it’s very difficult, no energy whatsoever, feels like dying; you sleep well at least.

  • @TheBigBrainBusters
    @TheBigBrainBusters3 ай бұрын

    Something interesting on why CD8+ cytotoxic cells are recruited as well is because, the deaminated gliadin peptides tend to induce production of IL-15, from the epithelial cells which cause epithelial damage, and in addition, the epithelial cells subjected to so many stressors end up expressing MIC-A molecule which is recognised by NKG2D receptor of the CD8+ T cells, thus further exercerbating the enterocyte damage

  • @lama-6598
    @lama-65982 жыл бұрын

    Best explanation for celiac disease ever

  • @tillygirl7450

    @tillygirl7450

    7 ай бұрын

    I agree.

  • @leavesofchange

    @leavesofchange

    3 ай бұрын

    it's ok. I've seen better.

  • @lola-mo5sh
    @lola-mo5sh4 ай бұрын

    Thanks

  • @ingridmazariegos1410
    @ingridmazariegos14102 жыл бұрын

    What app is used to create animated videos like this? I love it

  • @hebamoharam7287

    @hebamoharam7287

    Жыл бұрын

    I wish I knew as well

  • @bootatoboo

    @bootatoboo

    Жыл бұрын

    osmosis (the creators are graphic designers)

  • @khankaseparhnahagee9530
    @khankaseparhnahagee95304 жыл бұрын

    Hi.osmosis.good job

  • @meepmorp8614
    @meepmorp86144 жыл бұрын

    Having Celiac sucks but it is better than peanut allergy, I don't have a high risk of dying if I accidentally consume gluten but it will be a pain later on

  • @patricianoll1229

    @patricianoll1229

    2 жыл бұрын

    Celiac can end in cancer I don't know which is worst

  • @cspahn3221

    @cspahn3221

    11 ай бұрын

    Eh... one is taken seriously by the entire country, has legal regulations, is cared for by restaurants, and has an EPI pen solution. People with deadly gluten allergies(outside of Celiac) have absolutely nothing. A peanut allergy is a problem but is very easily manageable. Gluten is not.

  • @youare4553

    @youare4553

    9 ай бұрын

    Dying from Cancer is pretty serious too. Just because we don't have an immediate reaction doesn't make it "not as bad" Celiac is pretty serious. Especially because avoiding gluten in this world is quite hard! Chapsticks, toothpastes etc... it isn't something to downplay.

  • @michellelaroche2189

    @michellelaroche2189

    3 ай бұрын

    As someone with a co-occuring food allergy, I agree that the food allergy is much scarier.

  • @piyasaini8578
    @piyasaini85782 жыл бұрын

    CAC Curcumin capsule is prepared from the herb turmeric. The herb turmeric (Curcuma longa) contains the active compound curcumin that shows antioxidant, anti-inflammatory, analgesic, & immuno-modulator properties. These properties deal with the pain in abdomen, loss of appetite, indigestion, & improve overall digestion. It helps in building up the immunity of the small intestine to deal with the coeliac condition.

  • @patricianoll1229

    @patricianoll1229

    2 жыл бұрын

    I have fresh turmeric powder cook or raw don't help a bit

  • @ramanbhat8550

    @ramanbhat8550

    2 жыл бұрын

    @@patricianoll1229 you should consult a good ayurvedic doctor ....he can treat the disease properly ......You can also go to AIIA new Delhi... 🙏🏻

  • @53ajeem

    @53ajeem

    Жыл бұрын

    What about it is a blood thinner. Which is v dangerous to suggest as a layman to anybody who might already on blood thinner

  • @littlebitofhope1489

    @littlebitofhope1489

    3 ай бұрын

    "Building up immunity" would make Celiac worse, not better. The stronger your immune system is, the stronger the reaction you get. Remember, the body sees gluten as an invader like a virus, but mistakenly attacks your own body because no virus or bacteria is there.

  • @arronholcraft76
    @arronholcraft762 жыл бұрын

    I have celiac for about 5 months now still having problems even though I eat gluten free still having lots of mucus when I wipe no blood though so tired of being sick all the time it's affecting my work👎

  • @abrarhraiz5089

    @abrarhraiz5089

    Жыл бұрын

    I've the symptoms

  • @kkk16663

    @kkk16663

    Жыл бұрын

    Rice kill

  • @mooozzwozz8808

    @mooozzwozz8808

    Жыл бұрын

    When you eat gluten is stays in your system in about 6 months sometimes more and i am coeliac to so teust me just dont eat many may contains as it doese not help

  • @arronholcraft76

    @arronholcraft76

    Жыл бұрын

    @@mooozzwozz8808 I don't eat anything unless it says gluten free besides fresh fruit & vegetables & I still suffer to this day it's terrible

  • @Ericaaaaaaaaaa

    @Ericaaaaaaaaaa

    11 ай бұрын

    ​​​@@arronholcraft76 what did your doctor say?

  • @jezebelngwolf7472
    @jezebelngwolf74724 жыл бұрын

    Yay

  • @andrebantolo8231
    @andrebantolo8231Ай бұрын

    does glutenin have the same affect that gliadin does?

  • @bettadenu7
    @bettadenu74 жыл бұрын

    Is telogen effluvium and symptom ?

  • @abrarhraiz5089
    @abrarhraiz5089 Жыл бұрын

    I am nurse in the hospital okay guys? I have visited a lot of GI Dr but they failed to diagnose me, I did upper & lower endoscopy the first 1 has no villi the second has! Recently I complained of severe bone pain.. I am not under gluten free diet.. Could anyone help me please and guide me to do something 🙏🏿🙏🏿

  • @tillygirl7450

    @tillygirl7450

    7 ай бұрын

    As a 62 year old person diagnosed with Celiac Disease, the “severe bone pain” is something I am familiar with. Having Celiac Disease you must realize that you are susceptible to malnutrition, even though you are eating regularly. Because of this malnutrition you will be very low in a lot of nutrients and minerals in your body. The “severe bone pain“ for me was due to being severely low in Vitamin D3 (confirmed by blood test). I was prescribed to take by my medical doctor to take 15,000 I.U. of Vitamin D3 daily for 6 months and to come back to recheck my blood to see if my Vitamin D3 levels improved. Well, the “severe bone pain” went away COMPLETELY! Research yourself about the benefits of taking Vitamin D3 daily. If you do consider taking Vitamin D3, also consider taking (1) Vitamin K2/MK-7 , 90mcg daily with the Vitamin D3 because it will help the Vitamin D3 supplement get into your body/bones better.

  • @SlayAlison
    @SlayAlison6 ай бұрын

    Coeliac disease is so annoying like there’s not many foods at my school I can eat

  • @annahaque136
    @annahaque1365 ай бұрын

    👏👏👏👏😊

  • @nooralhoda8529
    @nooralhoda8529 Жыл бұрын

    can anymone help me ? i have a question : in normal case for people who don't have celiac disease do they don't absorbe gluten ?

  • @bootatoboo

    @bootatoboo

    Жыл бұрын

    malabsorption has multiple reasons, from mild to severe. check any concerns you have in PubMed (not google), uptodate as well is helpful and medically accurate

  • @blondsinger38
    @blondsinger38 Жыл бұрын

    Please explain HLA DQA1 05?

  • @AuroraLakes
    @AuroraLakes Жыл бұрын

    1/3 of the population is expected to have it. If you have ANY Northern European DNA there is any 85% chance of you have it. The reason little is known is because of the WFAOA Wheat Farmers Assc of America. In the 1940's they lobbied to have it quit being taught in the USA. They got their wish. From 1954-2004 only a single paragraph was dedicated to Celiac disease, and in that 50 years not a single word in that changed. That is why most Drs have no idea what the symptoms look like. I suffered for over 23 years until it turned into Duhring disease. I am self diagnosed after going to 5 different Drs. I am retired from medicine, and finally healthier than I have been in decades.

  • @littlebitofhope1489

    @littlebitofhope1489

    3 ай бұрын

    You have the gene, but most people with the gene never get Celiac.

  • @fatimasandali6349
    @fatimasandali63493 жыл бұрын

    I love you 🖤

  • @taylornovia8911
    @taylornovia8911 Жыл бұрын

    You sound like the narrator from Academy of Ideas 😅

  • @theEsperantist
    @theEsperantist Жыл бұрын

    After inoculating myself with 25 Necator americanus hookworm larvae my celiac disease disappeared.

  • @youare4553

    @youare4553

    9 ай бұрын

    Stop it!

  • @littlebitofhope1489

    @littlebitofhope1489

    3 ай бұрын

    So do you still have worms?

  • @IsaacNewton1966
    @IsaacNewton19664 жыл бұрын

    Huh?

  • @nik8423
    @nik842311 ай бұрын

    Dermal papilla of *dermis *, not epidermis. Epidermis has rete ridges.

  • @gaylecheung3087
    @gaylecheung30873 жыл бұрын

    One of the worst of your many good ones

  • @maigidamd2462
    @maigidamd24622 жыл бұрын

    Living with the stigma of HSV 1 & 2 and not been able to have a healthy relationship was messing up my life until I got some super herbs from Dr igho KZread channel, I haven't had any Symptoms for some while now, after I did a test & I'm planning to get another test done. Am grateful & advise you help yourself also