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Question 5... Likely B although I need to brush up my reasoning. My first thought is brugada syndrome (v1-v3 elevation psuedo-rSr' pattern). I also know brugada syndrome is due to genetic defects in cardiac ion channels (evidence is familial sudden cardiac death) and is heritable and is more common in Asian populations. I don't have a good enough reasoning to argue why it is sodium vs potassium but in potassium channel defects I think I'd expect changes instead with T waves and Q-T segment. I can't remember which channels are affected in brugada although there are a few subtypes. The child was previously well (no prior symptoms of either sickness associated with kawasaki disease or chest pain with coronary artery occlusion, which would be unusual in a child of 5 years) so rule out D and F. The child's heart rate is 80bpm which may preclude an accessory pathway as I'd expect that to show some tachycardia or other ecg changes (p-r shortening) Excess sarcomeric protein might lead to some structural heart changes (potential murmur?) and cardiomegaly. This was not listed on examination. So rule out D

Regarding assignment, it's Kawasaki disease. There's a family history mentioned of a deceased 8 year old, presumably due to heart arrest which leads us to the main and serious complication of such disease which is a small vessel vasculitis affecting people of an asian descend and causes manifestation similar in the typical older population who experience myocardial infarction mainly due to atherosclerotic events. All the remaining options there's simply no data to back up such statements 😊

Subluxation means partial dislocation of its normal site and dislocation means completely outside of its normal site

Abnormality of cardiac sodium channels: Sodium channelopathies such as Brugada syndrome typically present with characteristic ST-segment elevations in leads V1-V3

Good morning medicosis❤

@MedicosisPerfectionalis

2 ай бұрын

Good morning!

Could you Do c.v.s physiology playlist ?

@MedicosisPerfectionalis

2 ай бұрын

See my Physiology playlist. It has many cardiac physiology videos.

My man

@MedicosisPerfectionalis

2 ай бұрын

Thank you!