CAR T-cell Therapy explained (Manufacturing process & how it works)

Ғылым және технология

Hey friends,
CAR T-cells are modified T cells which express tumor specific receptors. CAR T-cell therapy is therefore used as a treatment option against some sorts of cancer. How CARs (= chimeric antigen receptors) are expressed on T-cells will be explained in this video.
Best
Henrik
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References:
pubmed.ncbi.nlm.nih.gov/32301...
www.cancer.gov/about-cancer/t...
www.cancerresearchuk.org/abou...
Time Codes:
0:00 CAR T-cells in the fight against cancer
0:26 What are normal T-cells?
0:51 CAR T-cells
1:37 How CAR T-cells are produced
2:34 Mechanisms of action of CAR T-cells
3:03 Outro
#CAR #T-cell #Therapy #Cancer

Пікірлер: 26

  • @mikedaniels3009
    @mikedaniels3009 Жыл бұрын

    I salute in advance THE ONE Person who'll finally explain WHY they are called "T-cells".

  • @arshpreetsingh8971

    @arshpreetsingh8971

    Жыл бұрын

    Because they mature in Thymus gland

  • @mikedaniels3009

    @mikedaniels3009

    Жыл бұрын

    @@arshpreetsingh8971 aah, well done, truth be told, from one medical guy to another, no-one in the content creating community seems to care much about talking laypeople's language.

  • @Rocknload33
    @Rocknload334 ай бұрын

    Short and very informative video, thank you!

  • @AtronsTube
    @AtronsTube3 ай бұрын

    It's phenomenal explanation brother. Thank you! Keep up the good job.

  • @julioalexo
    @julioalexo2 жыл бұрын

    Thanks for the links!

  • @solonass.9481
    @solonass.9481 Жыл бұрын

    Well explained !

  • @mohamedsamir6751
    @mohamedsamir67512 жыл бұрын

    excellent summary

  • @rufinamenezes7712
    @rufinamenezes77123 ай бұрын

    Very informative video. Thank you very much

  • @swadhasingh6095
    @swadhasingh6095 Жыл бұрын

    Thank you it is very useful video .I have easily understand this topic

  • @cchiliman
    @cchiliman2 ай бұрын

    Really helpful, thank you

  • @Vietnam_Da
    @Vietnam_DaАй бұрын

    It is an inspiring opportunity of treatment. against cancer. I am really interested in Human Medicine and successful treatment against cancer and new treatment opportunities. My biggest dream is to become a surgeon and to doctorate about tumors and cancer and new their therapies.

  • @risharajkhowa5060
    @risharajkhowa5060 Жыл бұрын

    Amazing video

  • @deepanwitaray2382
    @deepanwitaray23822 жыл бұрын

    Very helpful video sir....Thank you.

  • @bencyber8595
    @bencyber8595 Жыл бұрын

    CAR-T cell chimeric antigen receptor CT19

  • @yahyayozbatiran
    @yahyayozbatiran2 жыл бұрын

    Could you please tell me how to design CARs? I understand CARs are delivered via lentivirus or CRISPR-Cas9 but how CARs are modified I mean there are so many CARs such as anti-CD19, anti-HER2 etc... If I want to design anti-CD123 CAR-T cells what are steps should I follow?

  • @madalinapopa1006
    @madalinapopa10062 жыл бұрын

    Can someone please tell me what protein is present on the surface of tumor B cells?

  • @ezekielzuniga8127

    @ezekielzuniga8127

    Жыл бұрын

    There are multiple proteins present on the surface of any cells. Malignant B-cells often times express CD-19. This is why CAR-T cells are engineered to express this protein.

  • @WhirlwindHeatAndFlash
    @WhirlwindHeatAndFlash Жыл бұрын

    Aye-moon

  • @vikky4209
    @vikky42092 жыл бұрын

    0:55

  • @maygapiano3318
    @maygapiano3318 Жыл бұрын

    Hello, I'm from China, and my mother is initially suspected of multiple myeloma, and she also wants to use this kind of treatment. Which city and hospital do you need to go to for this kind of treatment? thank you!Save my mother, I will thank you all my life! thank you

  • @henrikslab

    @henrikslab

    Жыл бұрын

    I am not a medical doctor, I am sorry not being able to help you. Please contact medical staff for those matters. I wish you and your mother all the best!!!

  • @avaxfuture8282

    @avaxfuture8282

    Жыл бұрын

    You can search it as immunotherapy on the internet as well. It is a form of immunotherapy.

  • @demogyani2419
    @demogyani24194 ай бұрын

    Waiting it for HIV.

  • @jugnu361
    @jugnu36113 күн бұрын

    CAR T TOTAL FAILURE

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