Objective of the lecture is to demonstrate how science can help solve clinical problems through imaging technology that opens a window into the brain’s mechanisms. Pediatric bipolar disorder is selected as a clinical illness model to study affective, cognitive and sensori-motor domains. On behavioral characterization, executive function, working memory, verbal memory attention and affect regulation were uncovered and shown to persist despite medication or illness status. The brain circuitry model was mapped to reveal impaired fronto-limbic, occipito-limbic, occipito-temporo-frontal, dorsal and ventral fronto-striatal, and cortico-cortical circuits. Recorded on 04.08.2015. [Show ID: 29608]
MIND Institute Lecture Series on Neurodevelopmental Disorders
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