Bone remodeling and repair

What is bone remodeling and repair? Bone remodeling is when old, brittle bone tissue is removed or resorbed and gets replaced by new bone tissue. Remodeling also occurs when reshaping your bones after a fracture or when repairing micro-cracks which form during ordinary activities, especially when your bones are under stress, like after lifting heavy weights. Find our full video library only on Osmosis: osms.it/more.
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Пікірлер: 173

  • @alfathrahagika7226
    @alfathrahagika72263 жыл бұрын

    why this gave me more understanding than my college..i love it

  • @kashifkhan7379

    @kashifkhan7379

    3 жыл бұрын

    Focused on lecture rather than Girls 😂😂😁

  • @This_or_Thatx1

    @This_or_Thatx1

    2 жыл бұрын

    Willl my bone density will grow after quitting drugs? I am 23+.

  • @amnafayyaz6768

    @amnafayyaz6768

    Жыл бұрын

    Because you are fool 🤣

  • @senankavanagh2382
    @senankavanagh23823 жыл бұрын

    Great video. ties everything together nicely. Decided to review bony remodelling today and fascinating what you can pick up again on revision. Initially when learning about bony remodelling I never really thought about the significance of RANKL , but with drugs such as Prolia , a RANKL inhibitor , it becomes obvious as to why the fundamental understanding of the physiological processes is vital to clinical practice with associated pathological states such as Medication related oseteonecrosis of the jaws. Many thanks.

  • @bayannasseral-harrasi6089
    @bayannasseral-harrasi6089 Жыл бұрын

    Bone remodeling in short: -Osteoblast release M-CSF & RANKL → Convert monocytes into osteoclasts → ↓ Bone mass -Osteoblast also release Osteoprotegerin (OPG) → OPG will inhibit RANKL → ↑ Bone mass

  • @rasheshdas
    @rasheshdas3 жыл бұрын

    The illustrations are fabulous

  • @uhlezza
    @uhlezza3 жыл бұрын

    This was really helpful plus the illustrations are adorable!! Thank you so much.

  • @degodaniyt6557
    @degodaniyt65572 жыл бұрын

    I would have loved to see more infromation about hormones and their influence on bone remodelling, such as the osteolytic effect of cortisol and such. An all-in-one video of what hormones affect bone remodelling.

  • @user-rk7ox1pb6x
    @user-rk7ox1pb6x Жыл бұрын

    Finally understood the mechanism after 5 retake. love this type of resource, really insightful and articulate.

  • @osmosis

    @osmosis

    Жыл бұрын

    We're glad it helped, Dhruv! 🙏🏼

  • @evakhwaiss7484
    @evakhwaiss74843 жыл бұрын

    I've searched more than 1 hour for a video like this, thank you so much 😍 this sums up everything i want about bone tissue 👏

  • @osmosis

    @osmosis

    3 жыл бұрын

    Hi Eva, Glad it was helpful!

  • @abel6298

    @abel6298

    5 ай бұрын

    Read your bible! (KJV, preferably) ♥‎

  • @DrDY-us4rg
    @DrDY-us4rg3 жыл бұрын

    That was exactly what was needed

  • @laurenndance
    @laurenndance3 жыл бұрын

    Pretty helpful! Thanks!

  • @MA-fd6kg
    @MA-fd6kg3 жыл бұрын

    Great video! Helped me a lot!

  • @sarahesse2979
    @sarahesse29796 ай бұрын

    Thank you for sharing. Please we would love to see more videos like this

  • @LuanTran
    @LuanTran3 жыл бұрын

    What a vivid way to present such hard topic. Thanks a lot !

  • @osmosis

    @osmosis

    3 жыл бұрын

    Thanks for your wonderful comment! 🥰

  • @mikhailkushadiwijaya1027
    @mikhailkushadiwijaya10273 жыл бұрын

    Simple yet deep and well explained. Thanks a lot. Please make more animationlike this. I really appreciate it. Gbu all team!

  • @osmosis

    @osmosis

    3 жыл бұрын

    Thank you Mikhail for that wonderful feedback!

  • @charmimgshahnaz7455
    @charmimgshahnaz74553 жыл бұрын

    Dear Osmosa,,, please make a video about closed fracture.. thanks a lot.

  • @paltrygorilla9151
    @paltrygorilla91513 жыл бұрын

    Thanks Bro! this really helped me.

  • @maymansourian7417
    @maymansourian74172 жыл бұрын

    Another great video by the Osmosis Team! Thank you!

  • @osmosis

    @osmosis

    2 жыл бұрын

    Thank you too! 🙏🏼

  • @melindaaa1404
    @melindaaa14042 жыл бұрын

    This is the perfect video for this subject. Thank you so much!

  • @osmosis

    @osmosis

    2 жыл бұрын

    Glad you think so!

  • @heathenwizard
    @heathenwizard3 жыл бұрын

    Great visuals and wonderfully concise and explanatory! Thanks so much!

  • @osmosis

    @osmosis

    3 жыл бұрын

    You're very welcome! Thanks for letting us know!

  • @jayarramos2300
    @jayarramos23003 жыл бұрын

    How about left humerus? How many months it takes before healing?

  • @mshaik435
    @mshaik4353 жыл бұрын

    Osmosis makes med school easy♥️love this channel. So accessible

  • @osmosis

    @osmosis

    3 жыл бұрын

    Yey! We're glad to be of help to your medical journey! If have time, feel free to sign up for a free trial at osmosis.org so you can access more of our video library and other study features. 😊

  • @wendyfer735
    @wendyfer7352 жыл бұрын

    Thank you!

  • @MinhNguyen-li2eb
    @MinhNguyen-li2eb2 жыл бұрын

    Amazing. Now i remmeber the core of a complicated process in our body. TKs a lot

  • @osmosis

    @osmosis

    2 жыл бұрын

    Glad to hear that, Minh! ❤️

  • @katharina6865
    @katharina68652 жыл бұрын

    Wow, this is really informative. Thank you! I lost 2 Parathyroids after a messed-up operation. Still don`t know how to deal with this, but trying and learning. 😰

  • @osmosis

    @osmosis

    2 жыл бұрын

    Sorry to hear that. Katharina. We hope you're doing better now. 🙏🏼

  • @foramsanghavi9328
    @foramsanghavi93282 жыл бұрын

    That's wonderfully explained..Made understanding very clear just in 5 min.. Thank you so much

  • @osmosis

    @osmosis

    2 жыл бұрын

    Glad it was helpful, Foram! ❤️

  • @lynnlive21
    @lynnlive213 жыл бұрын

    Thank u! ♡

  • @halobium3513
    @halobium35132 жыл бұрын

    excuse me but do you have a video explaining mechanism of healing of bone's fracture?

  • @khushishah2130
    @khushishah21303 жыл бұрын

    ❤️❤️.. plz make a video on osteoporosis

  • @rasheshdas
    @rasheshdas3 жыл бұрын

    Thank you very much

  • @Chuckbgd
    @Chuckbgd3 жыл бұрын

    thx! it help me a lot

  • @azouz5675
    @azouz56753 жыл бұрын

    why there is resorption in one side and the deposition in the other side not in the same side ?

  • @ayamohammed7753
    @ayamohammed7753 Жыл бұрын

    Great explanation ma sha Allah!

  • @Realmadridforever714
    @Realmadridforever7143 жыл бұрын

    One of the best video on bone remodeling

  • @osmosis

    @osmosis

    3 жыл бұрын

    Wow, thanks for that feedback!

  • @fevenre4969
    @fevenre49693 жыл бұрын

    Very brief vidio......Thanks alot

  • @alkynesofatoms9315
    @alkynesofatoms93158 ай бұрын

    Great, thank you.

  • @arshishamim4064
    @arshishamim40643 жыл бұрын

    nicely explained :)

  • @kuengatshomo7396
    @kuengatshomo73969 ай бұрын

    Wow thats so helpful...Thanks alot. In the midst of confusion and infodemic, its like a hopeful rays.

  • @osmosis

    @osmosis

    9 ай бұрын

    Glad it was helpful! 💫 🥰 💖

  • @alikadhim4546
    @alikadhim45463 жыл бұрын

    Amazing ♥️♥️♥️♥️ thank you very much

  • @marysakala1079
    @marysakala10792 жыл бұрын

    Very clear and straight forward

  • @osmosis

    @osmosis

    2 жыл бұрын

    Thanks, Mary! 👍🏼

  • @rethijja3331
    @rethijja33312 жыл бұрын

    This is amazing

  • @nihalgaber3403
    @nihalgaber34032 жыл бұрын

    I have a question please regarding Wolff's Law: if we say that Applied pressure results in bone resorption, while applied tension results in bone formation. is that correct or not?

  • @nothing_fancy692
    @nothing_fancy6922 ай бұрын

    Thank you!!! It makes so much sense now!

  • @osmosis

    @osmosis

    2 ай бұрын

    Glad to help! 😊

  • @ramokunupisekgwaila5033
    @ramokunupisekgwaila50332 жыл бұрын

    Well explained 👏👏👏, thank you so much 🙏

  • @osmosis

    @osmosis

    2 жыл бұрын

    Glad you think so, Ramokunupi! 🥰❤️🙏🏼

  • @ADAPTATION7
    @ADAPTATION72 жыл бұрын

    Parathyroid gland stimulates osteoclasts (not osteoblasts) for bone resorption to occur. Small mistake at 5:05.

  • @francesca186
    @francesca18611 ай бұрын

    hi, could you add the bibliography used to make this video? it was so useful to me and i'd like to read sources too

  • @osmosis

    @osmosis

    11 ай бұрын

    Hi Francesca! You may access this information when you hop on osmosis.org! Please feel free to sign up for the 7-day free trial (no card needed) anytime 😊

  • @requestcontrol1886
    @requestcontrol18863 жыл бұрын

    God bless you people

  • @melinaguillon2449
    @melinaguillon24495 ай бұрын

    Amazing content and animation! Thank you!

  • @osmosis

    @osmosis

    5 ай бұрын

    Most welcome, Melina! 😊

  • @GuidetteExpert
    @GuidetteExpert2 ай бұрын

    Are these cytokines that these cells use to signl or use as a communication to start og stop a process?

  • @wifaqjaborialbazy-4405
    @wifaqjaborialbazy-4405 Жыл бұрын

    excellent job

  • @osmosis

    @osmosis

    Жыл бұрын

    Many thanks! ❤️

  • @navyashreedegowl9352
    @navyashreedegowl93523 жыл бұрын

    U ppl.arw.doing such a great teaching ..thanks a lottt

  • @osmosis

    @osmosis

    3 жыл бұрын

    Hi Navyashree, thank you, we're glad you find our videos useful! :)

  • @cpbeauvoir
    @cpbeauvoir3 ай бұрын

    Watching this on my way to my test. Thank you

  • @osmosis

    @osmosis

    3 ай бұрын

    We hope it went well! 🙏🏼

  • @CHRISGURJAR
    @CHRISGURJAR2 жыл бұрын

    Awesome explanation. Loved it.

  • @osmosis

    @osmosis

    2 жыл бұрын

    Thanks, Chris! 😊

  • @arizarichie9446
    @arizarichie9446 Жыл бұрын

    how long is it ? how long the process go ?

  • @dr_blueman
    @dr_blueman7 ай бұрын

    Thank you. ❤

  • @osmosis

    @osmosis

    7 ай бұрын

    You're welcome 😊

  • @rosiefans863
    @rosiefans8638 ай бұрын

    Understand thanks. A lot

  • @osmosis

    @osmosis

    8 ай бұрын

    Happy to help 🙏🏼

  • @EkilRevolution
    @EkilRevolution2 жыл бұрын

    What do you think about bonesmashing?

  • @munishgupta2226
    @munishgupta22262 жыл бұрын

    Excellent presentation , but as far as I know osteoclasts doesn't produce COLLAGENASE , it is produced by osteoblasts actually , bone resorption by osteoclasts at it's clear zone (at ruffled borders) mediated by carbonic anhydrase , secondly it pump out hydrogen ions( after CO2 hydartion - H2CO3 formation - breakdown into Hydrogen and carbonate ions -then pump out hydrogen ions) which lowers pH , lysis of collagen in acidic media , which leads to bone resorption , Plz tell me if I m wrong

  • @1cloudshinobi
    @1cloudshinobi2 ай бұрын

    What is the duration of this process

  • @sufias1459
    @sufias14592 жыл бұрын

    Perfect👌Tnks✨🌸

  • @thomasbays8292
    @thomasbays8292 Жыл бұрын

    My daughter had PAO surgery. The coverage is good no doubt. She still has pain and is very thin, could bone remodeling be an issue?

  • @maja0247
    @maja02477 ай бұрын

    Thank you so much this is amazing

  • @osmosis

    @osmosis

    7 ай бұрын

    You're so welcome! 💖

  • @btsismybias8332
    @btsismybias8332 Жыл бұрын

    Thanks a lot !!!

  • @osmosis

    @osmosis

    Жыл бұрын

    We hope our video helped! 🥰

  • @mike.m4621
    @mike.m46213 жыл бұрын

    I had 12 years ago a femure fracture very ugly caused by a tumore. I had surgery ofcourse the doctor said he clean everything there very good and he put me a metal plate wich I still have now and than I had the chimioterapy treatment. After 3 years I started to go slowly to gym and workout slowly but still even now after years I still cannot do the exercises for legs I did before the fracture because some pain during workout. You think the femur after this damage has healed properly? I will like your opinion also. Thank you

  • @hananmohamed9302
    @hananmohamed9302 Жыл бұрын

    great vid

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks, Hanan! 😊

  • @eugenunesdemoraes2398
    @eugenunesdemoraes2398 Жыл бұрын

    Great video, thank you

  • @osmosis

    @osmosis

    Жыл бұрын

    You're welcome, Euge! 🥰

  • @mahuubao
    @mahuubao Жыл бұрын

    Excellent ... well done ...

  • @osmosis

    @osmosis

    Жыл бұрын

    Thank you, Mahu! 🙏🏼

  • @mehsudmedicos8768
    @mehsudmedicos87682 жыл бұрын

    very appreciable

  • @osmosis

    @osmosis

    2 жыл бұрын

    Thanks!

  • @honeybadger1621
    @honeybadger16212 жыл бұрын

    what if person diabetic? how will heal

  • @itxmfahadkhan
    @itxmfahadkhan Жыл бұрын

    You are a life saver ❤️

  • @osmosis

    @osmosis

    Жыл бұрын

    Always glad to help, Muhammad! 🥰

  • @mardenidres
    @mardenidres3 жыл бұрын

    Really hepful thank you so much 💜

  • @osmosis

    @osmosis

    3 жыл бұрын

    Our pleasure! 😊

  • @gauravgupta174
    @gauravgupta1742 жыл бұрын

    When the bone is getting remodeled due to stress fracture , does it add 2-3 inches in height growth . When fully recovered

  • @arh1511
    @arh15113 жыл бұрын

    Great

  • @HAA-wasteAcc
    @HAA-wasteAcc2 жыл бұрын

    holy shit that's so good

  • @BhaskarDrukGiri0688
    @BhaskarDrukGiri06888 ай бұрын

    Awesome

  • @swagMan253
    @swagMan2533 жыл бұрын

    Does this process take place in the skull bones like the jaw or cheekbones?

  • @karenk3986

    @karenk3986

    3 жыл бұрын

    Good question

  • @ranch-ng1gv
    @ranch-ng1gv Жыл бұрын

    I wish my actual lecture was that easy with less deatails :(

  • @llostudio4278
    @llostudio42782 жыл бұрын

    Really nice

  • @osmosis

    @osmosis

    2 жыл бұрын

    Thank you! 🥰❤️🙏🏼

  • @dunyaimanova9207
    @dunyaimanova9207 Жыл бұрын

    the best explanation 😍

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks, Dunya! 💕

  • @StiffAftermath
    @StiffAftermath2 жыл бұрын

    So...is bone death reversible?

  • @sitiulfaturrizqa3555
    @sitiulfaturrizqa35552 жыл бұрын

    woow I love this one, thank for amazing video :)))

  • @osmosis

    @osmosis

    2 жыл бұрын

    Glad you like it, Siti! 🙌🏼

  • @Vikrant-7812
    @Vikrant-781211 ай бұрын

    I'm gonna send this video to my professor 💀✌️

  • @ruveydalipa
    @ruveydalipaАй бұрын

    This is so good but i dont know english well so it was hard to understand😭😭 but tysm anyways that helped a lot🥹🫶

  • @Omar_11234
    @Omar_112343 жыл бұрын

    amazing❤❤❤❤❤❤❤❤❤

  • @UHFStation1
    @UHFStation1 Жыл бұрын

    This didn't really explain how the bones know what shape they're supposed to be. I am particularly interested to know why spinal stenosis doesn't reverse itself relieving pressure on the spinal cord.

  • @Kiran.2020
    @Kiran.20202 жыл бұрын

    You are the best ❤️

  • @osmosis

    @osmosis

    2 жыл бұрын

    Aww.. thank you Kiaan! ❤️

  • @crenapun57
    @crenapun573 жыл бұрын

    Tq

  • @vijayramaraju3522
    @vijayramaraju35222 жыл бұрын

    Hello Sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off fractured line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....

  • @Bassman7608
    @Bassman76082 жыл бұрын

    @5:03 I think you’re mistaken. Shouldn’t the osteoclast be reabsorbing bone to release calcium in the bone?

  • @osmosis

    @osmosis

    2 жыл бұрын

    Hi Kevin! Thanks for pointing this out. We've notified our team about this so they can have the information reviewed. 😊

  • @maryambukhari7635
    @maryambukhari76352 жыл бұрын

    Amaaaaazing !!!!

  • @osmosis

    @osmosis

    2 жыл бұрын

    🙌🏼 💕 ✨

  • @user-xp3cg6dz4h
    @user-xp3cg6dz4h4 ай бұрын

    This is nice

  • @aventadorgamer1575
    @aventadorgamer15753 жыл бұрын

    Medical college life is easier with osmosis! 💗💗

  • @osmosis

    @osmosis

    3 жыл бұрын

    Glad to be of help! 😊

  • @KhadigalMohamed
    @KhadigalMohamed6 ай бұрын

    Great ❤❤❤❤❤🥳🥳

  • @mariamriaz2311
    @mariamriaz2311 Жыл бұрын

    Where's repair???

  • @peednas711

    @peednas711

    10 күн бұрын

    It starts at 4:20

  • @lukeskywalkerjediknight2125
    @lukeskywalkerjediknight21253 жыл бұрын

    Monocytes looks like a friendly thing 😊

  • @wypy817

    @wypy817

    3 жыл бұрын

    Monocytes are the most badass myeloid cells

  • @grant4360
    @grant4360 Жыл бұрын

    I think there is a small mistake, yellow bone marrow does not produce blood cells as was indicated in the video. That is actually red bone marrow typically found in the epiphysis

  • @osmosis

    @osmosis

    Жыл бұрын

    Thank you so much for bringing this to our attention, Grant! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊

  • @hmzzrg5045
    @hmzzrg5045 Жыл бұрын

    I think there is a mistake at 2:41. Myeloid progenitor cells come from hematopoietic stem cells, not lymphoid stem cells.

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks for pointing this out! Our team will be reviewing this information and update the video as needed. 🙏🏻

  • @joewichterman1193
    @joewichterman11932 жыл бұрын

    My stupid bio teacher is making me learn this for a presentation tomorrow. Great vid if you have any clue what the stuff in it is. Does she think I’m majoring in orthopedics or something. No I’m just trying to understand transcription factors and how they affect bones. I’m screwed

  • @wypy817
    @wypy8173 жыл бұрын

    I just failed my exam because i never prepare for ortho sub the intro was so boring in my university lecture i need to start with this ✊🏻🤞🏻 wish me luck everyone i m gonna start studying this video give me so much hope i find it it very interesting and its very easy to understand this😁

  • @osmosis

    @osmosis

    3 жыл бұрын

    Hi Pitchet! You can rock this exam! If you can, you may sign up for a free trial at osmosis.org so you can access our entire video library and study resources to help you ace your exam. This might help! We won't be asking for your bank details or anything, so no worries. 😊

  • @panda-pw6eg
    @panda-pw6eg Жыл бұрын

    Nice

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks! 😊

  • @Einnalem7
    @Einnalem72 жыл бұрын

    Why do osteoclasts eat the osteocytes?