Bone remodeling and repair
What is bone remodeling and repair? Bone remodeling is when old, brittle bone tissue is removed or resorbed and gets replaced by new bone tissue. Remodeling also occurs when reshaping your bones after a fracture or when repairing micro-cracks which form during ordinary activities, especially when your bones are under stress, like after lifting heavy weights. Find our full video library only on Osmosis: osms.it/more.
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Пікірлер: 173
why this gave me more understanding than my college..i love it
@kashifkhan7379
3 жыл бұрын
Focused on lecture rather than Girls 😂😂😁
@This_or_Thatx1
2 жыл бұрын
Willl my bone density will grow after quitting drugs? I am 23+.
@amnafayyaz6768
Жыл бұрын
Because you are fool 🤣
Great video. ties everything together nicely. Decided to review bony remodelling today and fascinating what you can pick up again on revision. Initially when learning about bony remodelling I never really thought about the significance of RANKL , but with drugs such as Prolia , a RANKL inhibitor , it becomes obvious as to why the fundamental understanding of the physiological processes is vital to clinical practice with associated pathological states such as Medication related oseteonecrosis of the jaws. Many thanks.
Bone remodeling in short: -Osteoblast release M-CSF & RANKL → Convert monocytes into osteoclasts → ↓ Bone mass -Osteoblast also release Osteoprotegerin (OPG) → OPG will inhibit RANKL → ↑ Bone mass
The illustrations are fabulous
This was really helpful plus the illustrations are adorable!! Thank you so much.
I would have loved to see more infromation about hormones and their influence on bone remodelling, such as the osteolytic effect of cortisol and such. An all-in-one video of what hormones affect bone remodelling.
Finally understood the mechanism after 5 retake. love this type of resource, really insightful and articulate.
@osmosis
Жыл бұрын
We're glad it helped, Dhruv! 🙏🏼
I've searched more than 1 hour for a video like this, thank you so much 😍 this sums up everything i want about bone tissue 👏
@osmosis
3 жыл бұрын
Hi Eva, Glad it was helpful!
@abel6298
5 ай бұрын
Read your bible! (KJV, preferably) ♥
That was exactly what was needed
Pretty helpful! Thanks!
Great video! Helped me a lot!
Thank you for sharing. Please we would love to see more videos like this
What a vivid way to present such hard topic. Thanks a lot !
@osmosis
3 жыл бұрын
Thanks for your wonderful comment! 🥰
Simple yet deep and well explained. Thanks a lot. Please make more animationlike this. I really appreciate it. Gbu all team!
@osmosis
3 жыл бұрын
Thank you Mikhail for that wonderful feedback!
Dear Osmosa,,, please make a video about closed fracture.. thanks a lot.
Thanks Bro! this really helped me.
Another great video by the Osmosis Team! Thank you!
@osmosis
2 жыл бұрын
Thank you too! 🙏🏼
This is the perfect video for this subject. Thank you so much!
@osmosis
2 жыл бұрын
Glad you think so!
Great visuals and wonderfully concise and explanatory! Thanks so much!
@osmosis
3 жыл бұрын
You're very welcome! Thanks for letting us know!
How about left humerus? How many months it takes before healing?
Osmosis makes med school easy♥️love this channel. So accessible
@osmosis
3 жыл бұрын
Yey! We're glad to be of help to your medical journey! If have time, feel free to sign up for a free trial at osmosis.org so you can access more of our video library and other study features. 😊
Thank you!
Amazing. Now i remmeber the core of a complicated process in our body. TKs a lot
@osmosis
2 жыл бұрын
Glad to hear that, Minh! ❤️
Wow, this is really informative. Thank you! I lost 2 Parathyroids after a messed-up operation. Still don`t know how to deal with this, but trying and learning. 😰
@osmosis
2 жыл бұрын
Sorry to hear that. Katharina. We hope you're doing better now. 🙏🏼
That's wonderfully explained..Made understanding very clear just in 5 min.. Thank you so much
@osmosis
2 жыл бұрын
Glad it was helpful, Foram! ❤️
Thank u! ♡
excuse me but do you have a video explaining mechanism of healing of bone's fracture?
❤️❤️.. plz make a video on osteoporosis
Thank you very much
thx! it help me a lot
why there is resorption in one side and the deposition in the other side not in the same side ?
Great explanation ma sha Allah!
One of the best video on bone remodeling
@osmosis
3 жыл бұрын
Wow, thanks for that feedback!
Very brief vidio......Thanks alot
Great, thank you.
nicely explained :)
Wow thats so helpful...Thanks alot. In the midst of confusion and infodemic, its like a hopeful rays.
@osmosis
9 ай бұрын
Glad it was helpful! 💫 🥰 💖
Amazing ♥️♥️♥️♥️ thank you very much
Very clear and straight forward
@osmosis
2 жыл бұрын
Thanks, Mary! 👍🏼
This is amazing
I have a question please regarding Wolff's Law: if we say that Applied pressure results in bone resorption, while applied tension results in bone formation. is that correct or not?
Thank you!!! It makes so much sense now!
@osmosis
2 ай бұрын
Glad to help! 😊
Well explained 👏👏👏, thank you so much 🙏
@osmosis
2 жыл бұрын
Glad you think so, Ramokunupi! 🥰❤️🙏🏼
Parathyroid gland stimulates osteoclasts (not osteoblasts) for bone resorption to occur. Small mistake at 5:05.
hi, could you add the bibliography used to make this video? it was so useful to me and i'd like to read sources too
@osmosis
11 ай бұрын
Hi Francesca! You may access this information when you hop on osmosis.org! Please feel free to sign up for the 7-day free trial (no card needed) anytime 😊
God bless you people
Amazing content and animation! Thank you!
@osmosis
5 ай бұрын
Most welcome, Melina! 😊
Are these cytokines that these cells use to signl or use as a communication to start og stop a process?
excellent job
@osmosis
Жыл бұрын
Many thanks! ❤️
U ppl.arw.doing such a great teaching ..thanks a lottt
@osmosis
3 жыл бұрын
Hi Navyashree, thank you, we're glad you find our videos useful! :)
Watching this on my way to my test. Thank you
@osmosis
3 ай бұрын
We hope it went well! 🙏🏼
Awesome explanation. Loved it.
@osmosis
2 жыл бұрын
Thanks, Chris! 😊
how long is it ? how long the process go ?
Thank you. ❤
@osmosis
7 ай бұрын
You're welcome 😊
Understand thanks. A lot
@osmosis
8 ай бұрын
Happy to help 🙏🏼
What do you think about bonesmashing?
Excellent presentation , but as far as I know osteoclasts doesn't produce COLLAGENASE , it is produced by osteoblasts actually , bone resorption by osteoclasts at it's clear zone (at ruffled borders) mediated by carbonic anhydrase , secondly it pump out hydrogen ions( after CO2 hydartion - H2CO3 formation - breakdown into Hydrogen and carbonate ions -then pump out hydrogen ions) which lowers pH , lysis of collagen in acidic media , which leads to bone resorption , Plz tell me if I m wrong
What is the duration of this process
Perfect👌Tnks✨🌸
My daughter had PAO surgery. The coverage is good no doubt. She still has pain and is very thin, could bone remodeling be an issue?
Thank you so much this is amazing
@osmosis
7 ай бұрын
You're so welcome! 💖
Thanks a lot !!!
@osmosis
Жыл бұрын
We hope our video helped! 🥰
I had 12 years ago a femure fracture very ugly caused by a tumore. I had surgery ofcourse the doctor said he clean everything there very good and he put me a metal plate wich I still have now and than I had the chimioterapy treatment. After 3 years I started to go slowly to gym and workout slowly but still even now after years I still cannot do the exercises for legs I did before the fracture because some pain during workout. You think the femur after this damage has healed properly? I will like your opinion also. Thank you
great vid
@osmosis
Жыл бұрын
Thanks, Hanan! 😊
Great video, thank you
@osmosis
Жыл бұрын
You're welcome, Euge! 🥰
Excellent ... well done ...
@osmosis
Жыл бұрын
Thank you, Mahu! 🙏🏼
very appreciable
@osmosis
2 жыл бұрын
Thanks!
what if person diabetic? how will heal
You are a life saver ❤️
@osmosis
Жыл бұрын
Always glad to help, Muhammad! 🥰
Really hepful thank you so much 💜
@osmosis
3 жыл бұрын
Our pleasure! 😊
When the bone is getting remodeled due to stress fracture , does it add 2-3 inches in height growth . When fully recovered
Great
holy shit that's so good
Awesome
Does this process take place in the skull bones like the jaw or cheekbones?
@karenk3986
3 жыл бұрын
Good question
I wish my actual lecture was that easy with less deatails :(
Really nice
@osmosis
2 жыл бұрын
Thank you! 🥰❤️🙏🏼
the best explanation 😍
@osmosis
Жыл бұрын
Thanks, Dunya! 💕
So...is bone death reversible?
woow I love this one, thank for amazing video :)))
@osmosis
2 жыл бұрын
Glad you like it, Siti! 🙌🏼
I'm gonna send this video to my professor 💀✌️
This is so good but i dont know english well so it was hard to understand😭😭 but tysm anyways that helped a lot🥹🫶
amazing❤❤❤❤❤❤❤❤❤
This didn't really explain how the bones know what shape they're supposed to be. I am particularly interested to know why spinal stenosis doesn't reverse itself relieving pressure on the spinal cord.
You are the best ❤️
@osmosis
2 жыл бұрын
Aww.. thank you Kiaan! ❤️
Tq
Hello Sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off fractured line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....
@5:03 I think you’re mistaken. Shouldn’t the osteoclast be reabsorbing bone to release calcium in the bone?
@osmosis
2 жыл бұрын
Hi Kevin! Thanks for pointing this out. We've notified our team about this so they can have the information reviewed. 😊
Amaaaaazing !!!!
@osmosis
2 жыл бұрын
🙌🏼 💕 ✨
This is nice
Medical college life is easier with osmosis! 💗💗
@osmosis
3 жыл бұрын
Glad to be of help! 😊
Great ❤❤❤❤❤🥳🥳
Where's repair???
@peednas711
10 күн бұрын
It starts at 4:20
Monocytes looks like a friendly thing 😊
@wypy817
3 жыл бұрын
Monocytes are the most badass myeloid cells
I think there is a small mistake, yellow bone marrow does not produce blood cells as was indicated in the video. That is actually red bone marrow typically found in the epiphysis
@osmosis
Жыл бұрын
Thank you so much for bringing this to our attention, Grant! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊
I think there is a mistake at 2:41. Myeloid progenitor cells come from hematopoietic stem cells, not lymphoid stem cells.
@osmosis
Жыл бұрын
Thanks for pointing this out! Our team will be reviewing this information and update the video as needed. 🙏🏻
My stupid bio teacher is making me learn this for a presentation tomorrow. Great vid if you have any clue what the stuff in it is. Does she think I’m majoring in orthopedics or something. No I’m just trying to understand transcription factors and how they affect bones. I’m screwed
I just failed my exam because i never prepare for ortho sub the intro was so boring in my university lecture i need to start with this ✊🏻🤞🏻 wish me luck everyone i m gonna start studying this video give me so much hope i find it it very interesting and its very easy to understand this😁
@osmosis
3 жыл бұрын
Hi Pitchet! You can rock this exam! If you can, you may sign up for a free trial at osmosis.org so you can access our entire video library and study resources to help you ace your exam. This might help! We won't be asking for your bank details or anything, so no worries. 😊
Nice
@osmosis
Жыл бұрын
Thanks! 😊
Why do osteoclasts eat the osteocytes?