Biochemistry | Enzyme Inhibition
Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will present on enzyme inhibition. We hope you enjoy this lecture and be sure to support us below!
Join this channel to get access to perks:
/ @ninjanerdofficial
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | / ninjanerdscience
PAYPAL | www.paypal.com/paypalme/ninja...
SOCIAL MEDIA
FACEBOOK | / ninjanerdlectures
INSTAGRAM | / ninjanerdlectures
TWITTER | / ninjanerdsci
@NinjaNerdSci
DISCORD | / discord
#ninjanerd #EnzymeInhibition #Biochemistry
Пікірлер: 230
This man single handedly training all of the world's future physicians.
If every one of Ninjas subscribers gave him $1, he would have $500,000. These lectures are better than any university class I've had.
@homiesuncensored
3 жыл бұрын
I totally agree with you, Seeta! This is awesome work
@drjawad92
3 жыл бұрын
More than one million $ now!
@altlipmsho7315
2 жыл бұрын
@@drjawad92 yaaa it's so awesome
@alexandruionut8553
2 жыл бұрын
I. m sure at the moment he. s making good money. He deserves everything!
@zb6070
2 жыл бұрын
1.7 million now
As a college student, I am broke. But! When I graduate med school, YOU dear Ninja Nerd Angels are getting a hefty chunk of change from me!
@akashalihazarika4690
4 жыл бұрын
That's something on my bucket list too !
@smithmavis1
4 жыл бұрын
I can't even afford a cup of coffee! Ninja Nerds has been a blessing beyond words. They are also on my bucket list!!
@Dopamine-.-
3 жыл бұрын
it's my 2nd year of medical school (my first if we didn't count the preparatory year )and I started to watch this channel it's really really great , I thought it has at least 5mil sub
@danpalu2308
3 жыл бұрын
5 dollar now is better than good intentions later. Just saying ;) Skip that next beer and you're set.
@shanksLUL
3 жыл бұрын
You have good intentions, but your gonna be broke af after medschool for a good 4-5 years lol. I promise you. Maybe after 6-10 years after finishing medschool, you will make better money.
This guy explains wayy better than my lecturer at the uni !
I don’t even know how to thank you for this. I have studied for hours without understanding and your 30 minute video solved the problem😭
dude i must say your videos really are the best. Usually I can't sit through anything longer than 10 minutes so with longer videos skip to where i can see the entire board so i have all the data i need, but your explanations are so well done that i sat through the entire video, without dosing off despite the fact that it's 3 am. Thanks again for the amazing lessons man, keep up the good work!
@Osteoclast
Жыл бұрын
same ong, damn thats a 2year old comment
Your'e such an amazing teacher I'm so glad that I found this channel. Lots of love to The Ninja Nerd Team from India
This is the first channel I have subscribed to. For the first time, I have understood this lesson. I always just watch videos and move on, but this channel is a safe classroom, I can be confident in understanding my PhD program. Thank you
Wow! You've been such a revelation to me. Thank you very much. These videos are obviously very easy to understand, and they give me so much confidence in Bich now.
No book can explain like you!!!! Thank you soo much! I love your lessons :)
I just memorized the effects of inhibition for 4 years during pre-med without understanding no matter how much I tried reading about it. Now I am so happy to find your channel to understand the materials intuitively in med school LOL. DEFINITELY is gonna help me retain all of this long term now. I was hesitant at first seeing the first MM equation video's derivations but it makes perfect sense why you went through the trouble to explaining the whole thing. THANK YOU!
@berniceamanor8162
2 жыл бұрын
I want to be your friend
OMG!!!! You save my life for passing with high distinction in my first year Biomedical Science. Now, I am in the second year and I am really confident that I can pass with high distinction again. Thank you and god bless you!!
Thanks to you I passed biochemistry, really great work, keep doing it because you help a lot, thanks to you from the heart...!!!
You’re an awesome teacher, your completely explain things that I’ve tried to get for months! Tank you so much... keep making videos :D
Its been really great watching your videos and you are making medical school so much easier for a lot of us out here. thank you so very much and God bless
I learn more from your vids that I do in class
This guy is great. Wish he had videos about everything I'm learning this semester because my professor sucks.
god bless this has been soooo helpful!! Thankyouuu
Thank you for doing a thorough explanation. I appreciate that you included examples.
Thanks for your efforts and all whom helping you to make these lecture clear and easy 🙏❤️😊❤️😊😊❤️
much appreciation for taking the time to draw this all out :)
I am currently for my pharmacy and poisons board exams and this video was really helpful. thank you. God bless you.
Great explanations, very clear, very helpful. THANK YOU!
Your literally the best teacher ever! Never have I understood topics like this before your videos
His lectures are so clear and easy to understand
I love your videos they are so creative as I'm a visual learner, It helps a lot in Med School.
man if i pass my biochem final im gonna pray for you so much ill start appearing in your dreams
Slight correction: for a competitive inhibitor higher km = decreased affinity for substrate
@jakephelps4766
2 жыл бұрын
you are essentially saying the same thing....in the last video he talked about how at 1/2vmax [s]=km so the km is basically telling you the concentration of substrate required to reach vmax....he talked about how basically increasing km results in decreased substrate affinity i.e you need to increase [s] to reach vmax
@CutiePieDIY
Жыл бұрын
thank you i was just wondering this!!
Keep your mind clear 😂😂😂 cox😂😂 this guy has a sensational sense of humor
I'm a french student who's not good at english but i understand everythink thank you for this video
These videos are addictive! 😊😊
This is really helpful ! Thanks ❤
You are the best " a learned man and cool guy "
You are helping humanity by teaching thanks so much
I think something is off about the Competitive Inhibitor. If the Substrate Affinity goes up, the KM decreases, but as the Substrate Affinity goes down the KM increases. You explained that to beat the Competitive Inhibitor the Substrate Affinity must go up thus the KM will increase. No, I think the correct explanation is because the Competitive Inhibitor beat the Substrate's Affinity, the Substrate Affinity goes down hence the KM goes up. Because the effect of Competitive Inhibitor is KM goes up but Vmax unaffected. That's all from me, anyway amazing video! Really helps me understand difficult concepts!
@TheForeverFalcon
4 жыл бұрын
Why does the Km decrease of 'uncompetitive inhibition' then? How has the substrate infinity increased?
@chelsysagastume8296
4 жыл бұрын
yes, it's true the rise in Km means that there is a lower substrate affinity for the substrate and enzyme to make ES complex due to low km it takes for inhibitor as well as the high affinity for the inhibitor. So because enzyme has high affinity for the inhibitor it must be fixed. To fix it he has to increase the substrate concentration.
@gleefulreaper
2 жыл бұрын
Thnx ❣
@mariapalacios533
2 жыл бұрын
I agree! but awesome video still...
Thank you soo much professor, you have a gift of making anything understandable!!!
WOW!! You are the best!! Thank you so much for being a super duper awesome teacher!!!
I can’t imagine that I could have learnt it better Thanks doctor 💙💙💙💙🌎
Thank You so much. Only your video makes me understand of the concept. :)
Really helpful, d best I've seen...tnk u Ninja
Love it. Thanks, Z.
Am I student and wow...ur videos are really helpful....Was asking u guys to make a video on protein purification methods as well
At the end of the non competitive inhabitation, how is the inhabitant released and the pocket fixed or removed?
Very helpful video .thank you sir.
Love this guy!
Explanation really very clear.Thnks a lot
thank you for this video,really nice
Thanq for preking up the learning process😊.I have a doubt :disulfiram used to treat chronic alcoholism is an example of what type of inhibitor?
Thank you so much. I did great on test just by watching your videos
You are the best tutor ever
Thank you so much for this video!!
Sir your lecture are brilliant and easy to understand.... and one thing I have request you to upload a snap of lecture you've done on board.... it is easy for revision also.....🙏
Woooow I just love ur lectures
Thank you much...how awesome
This is amazing 🤩 Thank so much ninja nerd for making all these biochemistry lecture videos I really appreciate it 😊 could you replace my lectures on my biochemistry module?🥺
Thank you Zach 😻
Thanks this really helped with my studies, I study medicine in barbados
thanks professor Ninja! 🙌🏼
nice job this has helped me alot
careful! at 8:56! from what i understand, km has an INVERSE relationship with affinity. what's written on the board looks fine but when you say "km, or affinity, increases" is not!
@RajKumar-xy3mr
6 жыл бұрын
Km increases , it increases the substrate(S) concentration and decreases the substrate affinity
Very thankful … saved my marks in university
Thank you!
Sir plz make a video on metabolic acidosis and alkalosis...and buffer system
So good!!!
Could you please make a nucleotide synthesis video? I really miss a nice and well-explained biosynthesis and degradation of purines and pyrimidines on youtube... Why won't you be the first? :))) Pleeeaasseeee
Lehninger takes 3 pages to explain this. you make life easier bro. love you
Bravo! Very well done - excellent superlative work, mate!
fantastic teaching
These are the best writing markers I’ve seen, far better than Expo. Where can I get these??
Brah, best lecture class ever😅
Thank you so much
Ninja nerddddddddd❤❤❤❤❤. I don't even know how to say thank you. Thank God for u o 🙏
Thankyou so much!
thank you!!
Are the videos in the playlists in order ??? because at times they dont seem to follow a content flow
Wow!!!!!! You are the best teacher i've ever seen😳😳😳😍👏👏👏👏 You are a huge help for online international students like me who do not have any teacher just pdfs and some imperfect videos! But YOU are the best, you are better than all videos and all PDFs! Please keep doing new videos as all Health science students deeply need you! Thank you for your being. I just started to watch all of your videos and i hope to watch more videos uploading on youtube from you🙏💯💯💯💯💯
One day I hope to be this good! Trying to be a prof 😭
Fantastic!
Dude, I just got an A in Biochem with the help of your explanations! I am eternally grateful! Greetings from Croatia ✌
you’re the reason i’ll be able to go to med school one day
very helpful
You are amazing❤
amazing explanation 🤟
Thanks!
good explanation but I've got one question or one thing I don't understand. You said that when the substrate concentration will increase the Km will increase to and so the affinity. In the first part of the video you said that a high Km means that the enzyme has low substrate affinity. So how can the affinity become high in competitive inhibitor when the Km and substrate concentration increases?
@gleefulreaper
2 жыл бұрын
This , i am confused as well
@anthonypeltier4039
2 жыл бұрын
Their website is up and running with all these videos and extensive notes on them, so I guess more extensive than the videos are already, I’m going to check it out to seek clarification
@Dr.Ghalebsaleh
15 күн бұрын
I think the idea, some enzymes have low affinity towards substrate so it has to reach high km in order to compete with the inhibitor and make the reaction
man you are awesome ❤️
Thanks sir
i'm very confused, last video you said increase in Km results in decrease of substrate affinity . so how do they both increase in this case? arent they inversly proportional?
thank you soo much
How can a certain amount of substrate in a cell be specific when there is different amounts of enzymes in a cell at any given moment?
Hi Ninja nerds. Do you know the exact order on how to view this playlist? Im ready to unlearn and relearn biochemistry.
Thank you Thank you Thank you!!!
Thanks a lot 🔥
Thank you so much bro
It makes everything so easy . Really helpful ,keep going,😊
For the longest I thought the active site changes shape when the inhibitor bind to the allosteric site. Will it change shape? Or I got that totally wrong during my university lecture.
You are the best✊✊✊
loved the Cox joke at the end
amazing
You are best.tank you