Big Thinkers - Ralph Merkle [Nanotechnologist]

Big Thinkers is a former ZDTV (later TechTV) television program. It featured a half-hour interview with a "big thinker" in science, technology, and other fields. Interviews were filmed in a 16:9 format and intercut with public domain material from the Prelinger Archives. This archival footage (mostly film clips from the 1940's and 50's) was used to create visual metaphors highlighting the speaker's points.
This episode features Ralph Merkle. He is a pioneer in public key cryptography, and more recently a researcher and speaker on molecular nanotechnology and cryonics. Merkle appears in the science fiction novel 'The Diamond Age', as one of the heroes of the world where nanotechnology is ubiquitous. He was a distinguished professor in the College of Computing at the Georgia Institute of Technology. In addition to his work at Georgia Tech, Merkle is also a director of the Alcor Life Extension Foundation, of Arizona. In 1988, he became a research scientist at Xerox PARC, until 1999. Subsequently he worked as a nanotechnology theorist for Zyvex, returning to academia in 2003 as a Distinguished Professor at Georgia Tech.
(Text from Wikipedia)

Пікірлер: 22

  • @oker59
    @oker593 жыл бұрын

    Richard Feynman thought of using an electron microscope to make nano-manufacturing happen. Drexler noted S.T.M(Scanning Tunneling Microscopes, something very new when Eric Drexler first started thinking about nanotechnology), and Proteins. But, the protein route ran into the protein folding problem. It is an astronomical combinatorial problem that still hasn't been solved deductively. But, recently, like December 2020, an A.I. group showed they can approximate protein folding to a reliable degree. I wasn't really aware that they didn't really make it available. But, recently, the David Baker team improved it(being able to calculate protein complexes, and hence protein machines), and made it available. Suddenly, the alphafold team made their software a lot more available. Within a few weeks, the David Baker team for one solved 4500 proteins. And, that was on a computer with the power of a gaming machine. At this point, they could probably create nano-manufacturing - if they wanted to.

  • @oker59
    @oker593 жыл бұрын

    Richard Feynman, back in 1959 thought of making nano-manufacturing happen by means of electron microscopes. I've seen atom by atom assembly by electron microscopes; but, for some reason, they can't seem to build big things or something. I'm still waiting for the next electron microscope announcement. Eric Drexler noted S.T.M's, and Protein's as a way of making nano-manufacturing happen. Much the same can be said for S.T.M's that I said about electron microscopes above. Another pathway that Eric Drexler didn't mention in his "Engines of Creation" was DNA. Nanotechnologists have made software that can design and build DNA(and RNA) nanostructures in minutes. It's still a little hard to envision remaking the world with DNA nano-machines. Perhaps Eric Drexler's favorite pathway was proteins. But, that ran into the hardest problem in biology(next to the origin of life itself) - protein folding problem. Well, last December, some alphafold team, more or less, solved the protein folding problem They didn't come up with a deductive solution; they showed they approximate how amino-acids can fold into proteins . . .. very reliably and pretty close to atomic resolution. i'm thinking they put a moratorium on it, to try to take stock and figure how they think they can put this technology in the right hands. Well, a week or so ago, they lifted this. And, the David Baker team showed they have an improved software that can do protein complexes, and not just one protein at a time. Hence, you could design nano-machines. They can do this in like minutes. They day they've solved 4500 proteins in the time they made their software available. So, could prove interesting how fast they make nano-manufacturing systems.

  • @CalumnMcAulay
    @CalumnMcAulay12 жыл бұрын

    excellent series!

  • @oker59
    @oker5910 жыл бұрын

    . . . good.

  • @JodsLife1
    @JodsLife19 жыл бұрын

    look @ those computers...this was made in the '90s !!

  • @nephildevil
    @nephildevil4 жыл бұрын

    The cryonics argument is a Pascal's wager argument I think, it's not new and can be applied to all discussions of afterlife, also the more traditional religious ones 🤔

  • @oker59
    @oker599 жыл бұрын

    Seems to me, life dies because either 1) food runs out, or 2) some system gets plugged up, clogging the dynamics of the system somewhere. There's also 'killing' from hunter/prey relationships. It's not just atoms in a bad arrangement. Life is a dynamical system; it can overcome misarrangement of atoms.

  • @oker59

    @oker59

    9 жыл бұрын

    imagine a nuclear powered aircraft that can stay in the air for twenty plus years, armed with lasers; essentially unlimited ammo! I just thought of it, and well, in relation to Merkle's dad's project mentioned here, I couldn't help sharing!

  • @CeeDee6969
    @CeeDee696911 жыл бұрын

    hey merkle, can i get the same bracelet? thanks! see you in the future

  • @calvinsylveste8474
    @calvinsylveste84743 жыл бұрын

    Still waiting...

  • @oker59

    @oker59

    3 жыл бұрын

    still waiting for your god to make heaven on this Earth, right now.

  • @calvinsylveste8474

    @calvinsylveste8474

    3 жыл бұрын

    @@oker59 Still waiting for this tech to move from the realm of scientists to engineers, loon.

  • @oker59

    @oker59

    3 жыл бұрын

    @@calvinsylveste8474 it will prove interesting how much longer it takes them . . . i've been predicting the nano-manufacturing revolution will happen before SpaceX lands a man on Mars. Right now, I'm feeling pretty good about my prediciton!

  • @calvinsylveste8474

    @calvinsylveste8474

    3 жыл бұрын

    @@oker59 That blows chunks, considering SpaceX will not be landing anyone on Mars for the foreseeable future.

  • @sorsocksfake
    @sorsocksfake11 жыл бұрын

    Haven't heard of it. The Galactic Committee would not be pleased... there's this rule about sticking to your own solar system as long as you think a line on a map makes you different from someone on the other side of it. ;)

  • @leedaniel3465
    @leedaniel346511 жыл бұрын

    Well thats gonna b da end of alot jobs... across the world

  • @oker59
    @oker5911 жыл бұрын

    Ralph Merkle, "believe me, nobody wants to go back to the caves." This is the same guy who told me that humanity is not the technologically dependent species at google nanotech group discussions!(he essentially says the equivalent and contradicts himself in this apologetic video; it's what this videa is really all about, that life is about people and not some abstract idea about truth; he obviously doesn't understand the scientific philosophy and spirit). Today's scientists have picked up . .

  • @oker59
    @oker5911 жыл бұрын

    . . . up Parlay as the way to deal with the two cultures debate; they've practically picked it up by osmosis. That's all this video is, a front, saying Parlay when confronted with anti-science irrationalists, like Bill Joy.

  • @oker59
    @oker5911 жыл бұрын

    . . . nanofuture is coming before next year is out; in fact, I'd argue that with dna-nanotech being used to make nanotechnologies at will just this past year, we're in it; but, next year promises to dwarf however much exciting things dna-nanotech could do if that's all that happens. Good thing the nanofuture is going to happen with the Barrack Obama president than the Tea party Republican nazy party.

  • @lLessThan3l
    @lLessThan3l11 жыл бұрын

    Calm it troll.