Genuinly Johnny Depp as Captain Jack Sparrow in POTC i cannot imagine anyone else in that role

Seth! I love you for choosing F.Murray Abraham and a performance in Amadeus. Both him and Hulce are mesmerizing in it. What a film.

Just off of the top of my head: Robert Downey Jr. - Tony Stark - Iron Man Heath Ledger - Joker - The Dark Knight Arnold Schwarzenegger - T800 - Terminator J.K. Simmons - Terrence Fletcher - Whiplash Jesse Eisenberg - Mark Zuckerberg - The Social Network Adam Sandler - Howard Ratner - Uncut Gems Leonardo Dicaprio - Jordan Belfort - The Wolf of Wall Street Cillian Murphy - J. Robert Oppenheimer - Oppenheimer Keanu Reeves - John Wick Johnny Depp - Jack Sparrow - Pirates of the Caribbean Nicolas Cage - Red Miller - Mandy Ryan Reynolds - Wade Wilson - Deadpool Christoph Waltz - Hans Landa - Inglorious Basterds Jim Carrey - Truman Burbank - The Truman Show Jeff Bridges - The Dude - The Big Lebowski Christopher Lloyd - Doc Brown - Back To The Future Bill Skarsgard - Pennywise - IT

Andy Serkis as Caesar

1. Maria Falconetti - The Passion of Joan of Arc 2. David Bowie - The Man Who Fell to Earth 3. Besedka Johnson - Starlet 4. Simon Rex - Red Rocket 5. Regina Hall - Support the Girls 6. Kirsten Dunst - Civil War 7. Cameron Diaz - Being John Malkovich 8. Gillian Jacobs - Don’t Think Twice 9. Gloria Swanson - Sunset Boulevard 10. Chris Cooper - Adaptation Fun idea. Because so much of this is context around the actor in the moment, it becomes increasingly hard to gauge the further back you go in time, other than picking very early career performances. I don't have a particularly long list beyond my 10, but I went for a mix of qualifiers: - First significant film roles. (1, 2, 3) - Known actors excelling to a surprising extent. Could be playing against type or genre, or just being given the platform in a different/new context. (4, 5, 7, 8) - Casting choices which deepen the character through an existing relationship between actor and audience. (4, 6, 9) - A supporting performance which indelibly defines the property of the film to me beyond reasonable expectation. (10)

Kyle MacLachlan as Special Agent Dale Cooper!

Viggo came out and said that he would be willing to come back to play the role but idk if he could. like seth was saying

Chris Pratt as Garfield first overall draft pick

No heath ledger is crazy

Hugh Jackman as Wolverine going undrafted is craaazy

Willem Dafoe in the Lighthouse Mickey Rourke in the Wrestler Joaquin Phoenix in you were never really here Sigourney Weaver in all the alien movies Bill Nunn in do the right thing Adam Sandler in punch drunk love

The boys don’t fw De Niro anymore