Taking an exam on this tomorrow as well. Yours is the ONLY good video I can find on youtube describing transduction. In your face Sal Khan!!! Thanks.

Studying for my exam (just 5 days left)! Thanks for making this video; very clear and you have a very pleasant voice to listen to!

you make everything look so easy!! besides i love the tone of your voice!! i can listen to you a million times!! thank you!!

this is the first time im actually happy to hear the word "phosphorylation" :)))) ^^ thx so much :) keep up the good work prof :)

The most interesting explanation of the VERY dreary second messengers I've seen. Thanks!! Glad to have found your channel.

Thank you very much! My lecturer made this seem far more complicated than necessary. This video was very helpful. Keep up the good work!

You are so great!! Love the energy and enthusiasm.

Thank you so much! You have no idea how helpful this lesson was!

I LOVE your vids, they are all so thorough and extremely helpful!! THANK YOU

As a freshman I got hopeless when I first encountered cell biology, cell signaling cascade etc. I am trying to pick things up and REALLY THANKS for making them easier to understand! :)

You are brilliant! Please keep making videos, they are so helpful! I am in an 8 week Bio course and it is moving way too fast! 4 Chapters covered in 2 classes and then we get an exam. Its killer... Your videos are really helpful for those of us who are having to teach ourselves. Thank you!

This is perfect, thank you so much! I was looking for something like this forever

You are amazing speaker, I absolutely loved your presentation, especially the vibrant commentary to go with it. I wish you were my lecturer!

i have to give a seminar on this topic in an hour and this really helped, thank you.

This was an amazing video! You explained everything very well! Thank You :)

Great video! Very informative! Thank you!

Thank you so much! I finally understood signal transduction and 2nd messenger activation for AA based hormones. You made it make sense! Again thank you :-)

This was very helpful! Thank you!

I live your videos very much! It's very interesting, telling and helpful.

love it...really helpfull....you make such a complicated subject become so easy to understand..thank youuuu...:D

Awesome. Thanks for the fastastic explainations!

Terrific explanation!! Thank you!

I seriously love you!!!!! You're are a fantastic prof!!!! Im jealous of your students!!!!

that was so much better than the lecture from my professor

excellent-i am a high school physics teacher and biology, especially genetics amazes me- very clear- reminds me of photosynthesis a bit- i see themes and variations with the building blocks

Thank you for making this video. I have an exam tomorrow and it was extremely helpful. Thank you!!

extremely helpful, I am very grateful thankyou!

Really helpful, cheers! got an exam on this tomorrow!!

very good explanation Thank you !

i love this 1, it explain the signal transduction in simpler way

amazing. thank you looking for more.

Thank you so much. Very helpful!

Thanks !! very relaxing and i understand :D

Very helpful.. You makes complicated things so easy.. Really appreciating your efforts..

@Penguinprof

8 жыл бұрын

+Dr Anamika Gupta Thank you so much!!!

I'm loving it.. keep up the good work. Thanks :-)

Love watching your videos 😻😻😻😻😻

Outstanding. You are amazing!!!

Thank you Prof. Was really helpful. Do you have a video on the catalytic receptors for signal transduction?

Thank you for making this vid.

thank you for making this.

thank you so much for this video

#Signal #transduction is the process by which an extracellular signaling molecule activates a membrane receptor that in turn alters intracellular molecules creating a response. Transmembrane receptors span the cell membrane, with part of the receptor outside and part inside the cell. The chemical signal binds to the outer portion of the receptor, changing its shape and conveying another signal inside the cell. Some chemical messengers, such as testosterone, can pass through the cell membrane, and bind directly to receptors in the cytoplasm or nucleus. Sometimes there is a cascade of signals within the cell. With each step of the cascade, the signal can be amplified, so a small signal can result in a large response.Eventually, the signal creates a change in the cell, either in the expression of the DNA in the nucleus or in the activity of enzymes in the cytoplasm. -Creative BioMart

Thank you so much! This helped a lot :)

Enjoyed it!

Thank you very much!

Simply explained.... Nice one

@Penguinprof

4 жыл бұрын

Thank you 🙂

you’re a gem, thank you so much

@Penguinprof

Жыл бұрын

Thanks so much!

Amazing content! Thank you!

@Penguinprof

10 ай бұрын

I'm so glad it was helpful!

THANK YOU !!!

Thankkss! Really helpful video :)

soo helpful!! thank you:)

Phosphorylation is not synonymous with increased activity. In fact there are enzymes that are activated by dephosphorylation and inactivated by phosphorylation. Insulin in general dephosphorylates the enzymes it acts upon (despite initial tyrosine phosphorylation activity, it ultimately dephosphorylates and inactivates the target enzyme). For example, insulin stimulates glycogen synthase activity by dephosphorylating it. Check it out on wikipedia Keep it up !!!

thank you for the clarification :)

Wow amazing explanation...: loved it

@Penguinprof

3 жыл бұрын

Glad it was helpful!

you're saving me right now.

@ThePenguinProf Love, love your videos! What book would you recommend for someone that needs to get more in depth about Signal Transduction? I have an exam coming up. Thank you so much! :)

thank you

great!!!

ok that was awesome!

thanks so much ....

Awesome - thank you :-)

Sugarplum, you are amazing.....! thanks...have an exam later on tonight...So is it safe to say, In theory and very simplified, a simple bone fracture will trigger neurons to release hormones into the blood stream to reach the fracture site and bind to healthy osteoblasts and trigger transduction leading to bone cell division:}...? sorry for my lack of jargon, first year here....lol

Amazing video

@Penguinprof

8 жыл бұрын

+erangaj Thanks for watching!!!

you're perfect!

Lovvve you sooo much

thank you soooooooooooooooomuch

well i loved that

very good movie i like it very much... but i must add that you kind forgot to mention that phosphorylation also inhibits protein function cfr. glycogen synthase!!! (as every rule has its exceptions :p)

5:00 though 😂

@LivingHighAndMighty

7 жыл бұрын

Ayman Azizuddin LOL ikr? "I know right, the names are so sexy" XD I love it

Thank you for the A-HA! moment :-)

when the protein is phosphorylated by the TK, does the energy that was stored in the bond of the P in ATP go into the bond between the Protein and P? Is this why it's exciting, because potential energy is being passed from the ATP to the Protein-P, leaving the lesser potential energy ADP? Now the protein is energized, it can do more than just change shape and facilitate, it can do that and do work?

I have work in my spanish encampierio, be grateful for me watching , I only learn englishio. Today much thanks very Much , think I will pass my amplieflier puke.

thanks maaamm

Thank you for the video. Question: in 6:41 a cAMP is illustrated. Is there a 3',5' phosphate binding? It does look like a 4',5' binding.

@Penguinprof

4 жыл бұрын

It's not the best drawing - but yes, it's 3',5'-cyclic adenosine monophosphate

@jonaspfiffner7979

4 жыл бұрын

@@Penguinprof Great, this helps. Thank you again.

When you say lipid fevering do you mean hydrophobic or hyrophilic?

Thanks a lot. But phosphorylation doesn't always cause activation, it could also cause deactivation of a receptor protein.

Why can't the ligase move across the membrane? Is it due to different polarities or size? :)

awesome! (y)

I realy liked the video and ur way of teaching is very nice & "really the words are too sexy"

@Penguinprof

6 жыл бұрын

So glad you found it helpful! Thanks for watching!

that was cool

@Penguinprof

8 жыл бұрын

+JaysonR0 Thanks!

@thefryingpan951

8 жыл бұрын

you're welcome god blesss you

Good, thanks, Just cut the other talks, usually students are watching this on an exam night and are not really interested in other talks than the subject.

@David-qv9yy

9 жыл бұрын

EcoGranite yes I have a final in 2 days

pretty sure it is phos4Olation. but i'm no expert, tyvm great video :)

thats a biiggg needle