Are amlodipine and amlodipine besylate the same?

Are amlodipine and amlodipine besylate the same?.
No, amlodipine and amlodipine besylate are not the same. While they both contain the active ingredient amlodipine, they differ in terms of their chemical composition and formulation.
Amlodipine is a calcium channel blocker that is commonly used to treat high blood pressure and chest pain (angina). It works by relaxing the blood vessels, allowing for smoother blood flow and reduced blood pressure.
Amlodipine besylate, on the other hand, is a specific salt form of amlodipine. It is the most commonly prescribed form of amlodipine and is available in tablet form. The besylate salt is added to amlodipine to improve its stability and enhance its absorption in the body.
While amlodipine and amlodipine besylate have similar therapeutic effects, the besylate salt form is more commonly used because it has better solubility and bioavailability. This means that amlodipine besylate is more easily absorbed by the body and therefore may have a faster onset of action compared to other formulations.
To illustrate this further, let's consider an example. If a patient is prescribed amlodipine besylate 5 mg tablet, they would be taking a specific dose of amlodipine in the form of the besylate salt. However, if they were prescribed amlodipine without any salt form specified, it could refer to various formulations available in the market, including amlodipine besylate, amlodipine maleate, or amlodipine mesylate.
In summary, amlodipine and amlodipine besylate are similar in terms of their therapeutic effects, but they differ in their chemical composition and formulation. Amlodipine besylate is the most commonly prescribed form of amlodipine due to its improved stability and absorption in the body.
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