Aortic stenosis / Aortic valve disease : Pathophysiology Usmle step 1

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Aortic stenosis / Aortic valve disease : Pathophysiology Usmle step 1
Aortic stenosis is narrowing of the aortic valve due to calcification of the valve leaflets or valvular damage.
Aortic stenosis commonly occurs at an early age in patients with congenital bicuspid aortic valves.
The most common cause of aortic stenosis is calcification of the valve leaflets with age, with the prevalence of aortic stenosis increasing rapidly beginning in the 7th decade.
Aortic stenosis can also result from rheumatic fever. Though rheumatic fever is most strongly associated with mitral stenosis, other valves may also be affected.
Aortic stenosis is classically associated with syncope, chest pain and dyspnea on exertion. Aortic stenosis can progress rapidly, leading to sudden cardiac death.
Aortic stenosis can lead to left ventricular hypertrophy as the myocardium contracts against the narrowed valve opening. The myocardium outgrows its blood supply, leading to ischemia, progressively worsening chest pain, and dyspnea from pulmonary congestion.
Since aortic stenosis leads to myocardial ischemia and a fixed cardiac output, symptoms initially present during exercise. As the disease progresses, however, symptoms begin to occur at rest.
Aortic stenosis causes a pansystolic crescendo-decrescendo murmur heard loudest in the second intercostal space at the right sternal border.
The murmur often radiates to the carotid arteries.
The murmur decreases in intensity with decreased preload (such as in the Valsalva maneuver).
Aortic stenosis is associated with an S4 heart sound as well as “pulsus parvus et tardus,” or peripheral pulses that occur weak and late relative to the heartbeat, due to the slow emptying of left ventricle to the systemic circulation.
CXR shows left ventricular hypertrophy.
Echocardiography shows a narrowed valve area with increased transvalvular pressure gradient. Other findings may include left atrial enlargement and left bundle branch block. The most accurate way to quantify the transvalvular pressure gradient is with cardiac catheterization. aortic stenosis pathology
#aorticstenosispathology #aorticstenosis #aorticstenosisphysiology #aorticstenosisusmle #usmle #usmlevideos #usmlestep1 #mbbsvideos #drgbhanuprakash

Пікірлер: 63

  • @doctorbhanuprakash
    @doctorbhanuprakash4 жыл бұрын

    Medvizz Animated medical video lectures : 1200+ complete animated medical Video lectures includes all high-yield topics enough to cover all contents of mbbs and usmle step 1 . Subjects covered are - Anatomy , Physiology , Biochemistry , Pathology , Pharmacology , Genetics , Immunology , Microbiology , Histology , Embryology Clinical cases with detailed explanations for relevant topics High-yield notes for all above subjects Question bank wich covers all aspects of NEETPG , USMLE and PLAB software of Question bank mimic actual exam experience of respective licensing exams www.medvizz.com +91 9885588972 ( whatsapp )

  • @maxamedaxmed8651

    @maxamedaxmed8651

    9 күн бұрын

    Monay or free

  • @PerspinKayzer89
    @PerspinKayzer894 жыл бұрын

    It's the best explanation I have found about this topic, thank you so much, doctor.

  • @stinkydogfilms
    @stinkydogfilms3 жыл бұрын

    Thank you Doctor for a very thorough and easy to understand presentation. I am having TAVR done tomorrow on 5-3-21. This helps me understand more of what is going on. My gradient is 72, the opening of the AV is.6 the EF is 40%. I have an aortic aneurysm that is 4.3. I am aasymptomatic but passed out 3 months ago and 3 years ago. Mostly I feel good but do get out of breath when I exert myself. Because of presentations like yours I look forward to gettin TAVR and getting back to normal. I THANK YOU.

  • @doctorbhanuprakash

    @doctorbhanuprakash

    3 жыл бұрын

    Glad it was helpful!

  • @psid8
    @psid86 жыл бұрын

    very good video for usmle step 1

  • @nainaraina1777
    @nainaraina17775 жыл бұрын

    Very helpful sir...thank you

  • @venkateswararaobandarupall8695
    @venkateswararaobandarupall86954 жыл бұрын

    Aortic stenosis calcified and thickned biscusipid need surgery. Aortic flow:4.5m/s Gradient ppg70mmhg Mean 40mmhg. LVEF60% Good LV function.

  • @sinansaidmt
    @sinansaidmt4 жыл бұрын

    ME REALLY THANKFUL TO U SIR GOOD PRESENTATION 👍 that made to Concrete in My mind. Thank You 😊👍

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    Nice to hear that ... ur most welcome ...keep watching

  • @nishansubedi9076
    @nishansubedi90762 жыл бұрын

    Best concept clear sir

  • @user-yv6dv3wl1y
    @user-yv6dv3wl1y2 жыл бұрын

    very good explanation. realy thant u so much doctor

  • @doctorsathi7722
    @doctorsathi77226 жыл бұрын

    good video sir

  • @joodwaleed7570
    @joodwaleed75703 жыл бұрын

    thank you so much

  • @robertreagan5173
    @robertreagan51734 жыл бұрын

    Thank you so much . So wonderfully explained .

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    Ur most welcome , thanks for watching

  • @robertreagan5173

    @robertreagan5173

    4 жыл бұрын

    I have border line Left Ventricle Hypertrophy . Dr York on you tube in England taught that we should find out the reason. . You have brilliant explanation for a non cardiologist to understands and Ultra sound reports mild Aortic calcification.Now I can speak to my Doctor with a little bit of understanding , Again Your an excellent teacher .

  • @medzoklife
    @medzoklife4 жыл бұрын

    Crystal clear.

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    Thank u

  • @srirambhardwaj2343
    @srirambhardwaj23433 жыл бұрын

    Thank.you.so.much.sir.for.your.informative.lecture.

  • @doctorbhanuprakash

    @doctorbhanuprakash

    3 жыл бұрын

    Ur most welcome

  • @carbon1214
    @carbon12142 жыл бұрын

    Very good explanation of AS will be watching more in the future

  • @doctorbhanuprakash

    @doctorbhanuprakash

    2 жыл бұрын

    Tysm

  • @renuka.n2372
    @renuka.n23724 жыл бұрын

    Very good explanation thank you doctor....

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    Glad you liked it

  • @ASMR-kz8rh
    @ASMR-kz8rh2 жыл бұрын

    Speechless.

  • @doctorbhanuprakash

    @doctorbhanuprakash

    2 жыл бұрын

    🙏🙏🙏

  • @reeva89
    @reeva894 жыл бұрын

    Very well explained 👍

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    Thank you

  • @HafizahHoshni
    @HafizahHoshni6 жыл бұрын

    Simply excellent. Very grateful for clear, concise and well presented video. Thank you for the great channel. 8/8/2018 😊

  • @doctorbhanuprakash

    @doctorbhanuprakash

    5 жыл бұрын

    Thank u so much

  • @anuradhag3131
    @anuradhag31313 жыл бұрын

    Excellent 🙏

  • @doctorbhanuprakash

    @doctorbhanuprakash

    3 жыл бұрын

    Thanks a lot

  • @keerthanarengasamy4320
    @keerthanarengasamy4320 Жыл бұрын

    thank you so much .its is a life saver ]🙏🙏

  • @doctorbhanuprakash

    @doctorbhanuprakash

    Жыл бұрын

    You're welcome!

  • @ggg3172
    @ggg31724 жыл бұрын

    super bhanu

  • @doctorbhanuprakash

    @doctorbhanuprakash

    4 жыл бұрын

    thank u

  • @Islamic_reels_1111
    @Islamic_reels_11112 жыл бұрын

    Mind penetrating explanation 👌👌👌

  • @doctorbhanuprakash

    @doctorbhanuprakash

    2 жыл бұрын

    Glad you liked it

  • @vibhukulshrestha
    @vibhukulshrestha7 жыл бұрын

    Thank you, Sir!!! So, Sir SBP is high along with the pulse pressure???

  • @sinansaidmt

    @sinansaidmt

    4 жыл бұрын

    S Bro SBP high wid Pulse Pressure

  • @user-iu6to8hl2i
    @user-iu6to8hl2i25 күн бұрын

    Awesome ❤

  • @doctorbhanuprakash

    @doctorbhanuprakash

    25 күн бұрын

    Thank you! Cheers!

  • @user-yv6dv3wl1y
    @user-yv6dv3wl1y2 жыл бұрын

    kindly would u explain rheumatic heart disease

  • @awryoo7
    @awryoo7 Жыл бұрын

    RVH main ' a' wave prolonged hoti h to yaha left ventricular hypertrophy mai kaise ho rhi ?

  • @user-wg3yb8ud6l
    @user-wg3yb8ud6l3 жыл бұрын

    شكرا لكم خل يوجد له تدبير علاجي غير جراحي Thank you Is there Any curing drugs..pleas

  • @psid8
    @psid86 жыл бұрын

    I understand syncope and angina, but I do not understand dyspnea due to AS.

  • @doctorbhanuprakash

    @doctorbhanuprakash

    6 жыл бұрын

    Dyspnea due to pulmonary edema

  • @psid8

    @psid8

    6 жыл бұрын

    Dr.G.Bhanu Prakash thanks for reply pulmonary edema is due to increased LA pressure which causes blood to be backed up in the lungs? Thanks sir it is clear now

  • @rahulKUMAR-re7bs
    @rahulKUMAR-re7bs5 жыл бұрын

    Sir.. Please explain.. That, HOW A WAVE BECAME PROMINENT due to LEFT atrium enlargement 😑😑

  • @shashwatanand4526

    @shashwatanand4526

    2 жыл бұрын

    A wave in jvp means left atrium . A means atrium . Therefore if atrium is big a wave will become big .

  • @103priyadharshini.m8
    @103priyadharshini.m85 жыл бұрын

    Sir, please amke videos on murmur

  • @103priyadharshini.m8

    @103priyadharshini.m8

    5 жыл бұрын

    make*

  • @saraali-ho8fx
    @saraali-ho8fx16 күн бұрын

    Would you plz do the finding in echo in valves disease special AR ,MR,MS,MR The changes i mean in echo which one will be dilated Lv , which one will be Thicked Lv ,ect Plz never understand standard

  • @anna-liisakaindume8068
    @anna-liisakaindume80684 жыл бұрын

    🙌🏽🙌🏽🙌🏽

  • @spanishwithrobyn
    @spanishwithrobyn Жыл бұрын

    Is aortic stenosis the same thing as ventricular stenosis?

  • @doctorbhanuprakash

    @doctorbhanuprakash

    Жыл бұрын

    noo terminology is different as stenosis might be at septal level also

  • @rubykumari5907
    @rubykumari59076 жыл бұрын

    Ventriculaaaaaar

  • @saraali-ho8fx
    @saraali-ho8fx16 күн бұрын

    ❤❤❤

  • @doctorbhanuprakash

    @doctorbhanuprakash

    16 күн бұрын

    Thank u so much

  • @aboutafghanistan6479
    @aboutafghanistan6479 Жыл бұрын

    The member ship in India ruppee

  • @successuponfailure8648
    @successuponfailure86484 жыл бұрын

    Sir ..well explained. Want to.contact you regarding my condition . Can i get your email