Anticholinergic Drugs I Antimuscarinic Drug | Cholinergic Blocker | Para sympatholytic Drugs (HINDI)
An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and peripheral nervous system. These agents inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibres of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, and many other parts of the body. Anticholinergics are divided into three categories in accordance with their specific targets in the central and peripheral nervous system: antimuscarinic agents, ganglionic blockers, and neuromuscular blockers.
Anticholinergic drugs are used to treat a variety of conditions:
(1) Dizziness (including vertigo and motion sickness-related symptoms)
(2) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications.
(3) Gastrointestinal disorders (e.g., peptic ulcers, diarrhoea, pylorospasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
(4) Genitourinary disorders (e.g., cystitis, urethritis, and prostatitis)
(5) Insomnia, although usually only on a short-term basis
(6) Respiratory disorders (e.g., asthma, chronic bronchitis, and chronic (7) obstructive pulmonary disease [COPD]
Sinus bradycardia due to a hypersensitive vagus nerve
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