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@GoetzimRegen

4 жыл бұрын

Should we Take acetazolamide when we have corona?

I was falling asleep while studying about Mountain Sickness (something we all know sometimes happens even with interesting topics) and ended up finding this video in my effort to stay awake.The only thing I do not understand about it, is WHY it doesn't have the hundreds of thousands of likes more I would expect. Don't hesitate I will share your channel to all my colleagues. Greetings from South America!

@MedicosisPerfectionalis

2 жыл бұрын

Thank you so much 😊

@samerdahhan

Ай бұрын

Cuz he is lame as “flip” and his annoying comments ruin his videos

Please note that FiO2 is a constant: what decreases in altitude is the athmospheric pressure. The sum of the pressure of alll the gases of air is the athmospheric pressure. So if the athmospheric pressure decreases also the relative pressure of oxygen decreases, BUT FiO2 is always constant (around 20,93%).

@abhishekkushwaha9577

8 ай бұрын

The comment I was looking for…😹

@samerdahhan

Ай бұрын

Yep true

I swear this channel is underrated.

@MedicosisPerfectionalis

4 жыл бұрын

Thank you so much 😊

your humor is what gets me the hardest... makes the knowledge fuse to my brain

@MedicosisPerfectionalis

3 жыл бұрын

Thank you 🙏

How do you keep being so funny and making everything understandable? Thank you so much for the great effort

@MedicosisPerfectionalis

2 жыл бұрын

Thank you ☺️

The Fio2 is 21% at any altitude

great explanation, may god bless you

I enjoyed every bit of it,thank you❤️

Wow, man, your explanation is so incredible! A million thanks!

@MedicosisPerfectionalis

4 жыл бұрын

Thanks a million for your encouraging words:) Can you please help me by sharing?

This is so interesting as I’ve finally fully dedicated myself to long distance running, elevated training, and hiking along with following the stories of ultramarathoners like Goggins. He had swimming-induced pulmonary edema from SEALS training, HAPE from his 100+ ultramarathons at high elevations, and pitting edema on his leg caused by never properly taking care of himself or properly nurturing his body through the military, ultra runs, & maybe even his insane weight loss journey.

Thank u so much for the very useful video :)

Nice video! I am doing a presentation and I am looking for scientific articles about this. What sources did you base this video on? :)

Excellent job explaining this. Thank you! Can you also do one on Hypothyroidism?

@MedicosisPerfectionalis

4 жыл бұрын

That’s a great idea 💡

Sir, you are a genius, i dont have enough words to thank you!

@MedicosisPerfectionalis

Жыл бұрын

I appreciate you!

Loved this! I'll be taking pathophysiology classes next year in my nursing studies. You make learning fun and easy to remember with your upbeat style! Keep it up :)

Love your sense of humor!!! 😍😍😍

@MedicosisPerfectionalis

3 жыл бұрын

Thank you so much 😊

That was beautiful!!😍😍

@MedicosisPerfectionalis

3 жыл бұрын

Thank you so much 😊

I love the way you speak and explain.🔥😅

@MedicosisPerfectionalis

4 жыл бұрын

Thanks 🙏

Cool presentation. Interesting to follow. Learned some new things.

@MedicosisPerfectionalis

3 жыл бұрын

Thank you 🙏

It's magical how I felt from the first time that you are Egyptian 😂💗 you have the typical Egyptian manner of teaching and sense of humor. The only place where I like being told idiot 😂. All the best and thank you so much for offering such priceless lessons to us.

@MedicosisPerfectionalis

2 жыл бұрын

Thank you so much 😊

Thank you so much for this amazing lecture

@MedicosisPerfectionalis

Жыл бұрын

You’re most welcome! Would you please help me by sharing?

Thanks for the informative video

@MedicosisPerfectionalis

4 жыл бұрын

My pleasure 😇

Love your spirit bob

@MedicosisPerfectionalis

3 жыл бұрын

Thank you 🙏

Man this was so helpful

@MedicosisPerfectionalis

4 жыл бұрын

Awesome 👏 Thanks 🙏

Best explanation! Someday I might die but this glorious slide will remain forever hopefully.. It will remain forever.

@MedicosisPerfectionalis

4 жыл бұрын

Thank you so much, bro! Can you please help me by sharing?

wow. highly impressed

@MedicosisPerfectionalis

4 жыл бұрын

Thank you so much!

Interesting. Too little explanation on acclimatization process. As a mountaineer I know it can take up to a month to fully acclimatize. Many hypoxia/EPO response techniques can be used to build the blood to carry from the lungs. Most hikers will travel above 8000-9000ft and stop once reach first AMS symptom then travel down 500ft and rest. Some dive under water to hold the breath. win Goff was known to climb mt Everest in his shorts and his hypoxia breathing techniques obtained a Nobel prize to cause the same response.

👨‍🏫 Nephrology Playlist: kzread.info/head/PLYcLrRDaR8_d7bEi4DvucO73N4N_1vvPk

I didn't know you're Egyptian! All the respect, bro♥🔥

@MedicosisPerfectionalis

5 жыл бұрын

Thanks 🙏

@abdelbasetammar8003

3 жыл бұрын

الدم المصري عظمة يدكتور ❤️

@MedicosisPerfectionalis

3 жыл бұрын

Thank you!

@fatimahayssam120

3 жыл бұрын

Egyptians = noble mindness Love you ❤️

Sweet!

I have already study a case by lecturio that said "The FiO (fraction of inspired oxygen) at any altitude level on earth is 21%." 3.28

12:18 was really impressive 😢, i took a screen shot

I’m not sure if amount of oxygen changes with height or the lower partial pressure of oxygen is the case 🧐 Great content! Cheers from Poland!

@MedicosisPerfectionalis

4 жыл бұрын

Partial pressure

@mumugugu8033

4 жыл бұрын

@@MedicosisPerfectionalis At 3:30, you mention that FiO2 (F for fraction) decreases with altitude. I thought the FiO2 remains relatively consistent its just that overall pressure decreases therefore the partial pressure of O2 decreases.

Nicely explained baby 😊 thanks 🙏

@MedicosisPerfectionalis

2 жыл бұрын

Thank you so much 😊

This really is a fun way of learning hahhaahah thank you!

@MedicosisPerfectionalis

3 жыл бұрын

My pleasure 😇

Love you man😍

@MedicosisPerfectionalis

3 жыл бұрын

Thank you so much 😊

I used to live at elevation greater than 2500 m. When I descended to sea level I felt that the air is dense and somewhat uncomfortable but I acclimatized to it after 14 weeks. Why did this happen? I am supposed to feel more comfortable at sea level because there is more oxygen but what happened to me during those 14 weeks was the opposite.

@MB-tb6jy

4 жыл бұрын

Adaptation

In 16:00 minute there’s a wrong statement in this slide u write in the shifting to the left there’s a decreased y axis and this statement it’s wrong it will be (increasing) in the y axis( not a decrease)

Why does hypoxia cause cerebral edema? Does hypoxia also cause vasoconstriction of the cerebral blood vessels?

Are you seeing this Doctor Who is comparing CoVid to this?

@la1negrita

4 жыл бұрын

Dr.Cameron kyle...I'm here because of him.

@funvideos225

4 жыл бұрын

we are ahead of the people, government has it wrong,.

@basecretpal9218

4 жыл бұрын

Covid 19 = AMS!

Thank you very much brother I has recently discovered your channel , yes i mean it , it is a discovery ! This video is not the only video I watched in your channel , it is obvious that you are a high IQ man ما شاء الله . There are many things you were astonishing in the way you introdeuced them , among which i was very amzed in etymology , actually i used etymology late in the med school ... but i think it is very important . Excuse me ,,, The first thing changed in high altitude is not the FIO2 , what decreases is the PIO2 . The FIO2 which is the fraction of air comprised by O2 is not changed in high altitudes , it remains constant , i.e approximately 21 % . However PIO2 , which is given by the folowing equation , decreases : PIO2 = FIO2 x (Pb - 47 mmHg), where FIO2 is the fraction of oxygen in inspired air, Pb is the barometric pressure, and 47 mmHg is the vapor pressure of H2O at 37°C. The PIO2 is directly affected by the barometric pressure ( which i think is the hallmark change in high altitude , because of decreased weight of air above the measuring unit ) .

Oh wow now I get it why I’m sick yesterday after a climb .

@MedicosisPerfectionalis

4 жыл бұрын

Stay safe! Talk to your doctor if you have any medical questions!

Have gained alot, love ur way of teaching, LOVE from Pakistan❤

@MedicosisPerfectionalis

5 жыл бұрын

❤️❤️

F=mg as well so mg counts for weight where a=gravitational acceleration. :)))))

Big Fan Sir!!!

@MedicosisPerfectionalis

2 жыл бұрын

Thank you 🙏

Can I mirror this content?

I have so much fun just from listening to you hahahaha

@MedicosisPerfectionalis

4 жыл бұрын

Thank you so much 😊 And thanks for downloading from my website!

Good video

@MedicosisPerfectionalis

2 жыл бұрын

Thank you 🙏

What's the cause for Cerebral Edema???

I have RA. I live in western WA. I went on a trip to Spokane in eastern WA. I had much less inflammation in Spokane. Why would that be?

@MedicosisPerfectionalis

5 жыл бұрын

Thanks for the question, I want you to clarify some info: 1) Since you commented on a video about mountain sickness...Is there a difference in altitude between where you lived in Western WA and eastern WA? 2) When you say less inflammation, do you mean less chronic inflammation, less acute flares, less pain, less stiffness, or what? 3) Were you diagnosed with RA by a doctor? Is it confirmed? What serum antibodies are you positive for? If you want some privacy...You can send me a message on my Facebook page. Disclaimer: I am not a licensed physician so I cannot give any medical advice...Please talk to your doctor.

I wonder what is your specialty 🙄 and,thanks alot❤

where is the cyanosis?

I keep coming and I keep laughing jajajajaja

Hey, if Cerebral Blood vessels dilate during hypoxia, how does it cause Cerebral edema?

@MedicosisPerfectionalis

Жыл бұрын

Dilation of blood vessel increases flow of blood which raises hydrostatic pressure in capillaries. This increases the risk of edema.

What is the mechanism that makes pulmonary arteries react paradoxical to all other arteries in hypoxia?

@Blackeagleglef2

3 жыл бұрын

Redirecting bloodflow to Alveoli that has more oxygen from ambient.

U r Gr8

@MedicosisPerfectionalis

4 жыл бұрын

I am humbled

المصريين حواار❤️تسلم يدوك❤️

@MedicosisPerfectionalis

2 жыл бұрын

Thank you 🙏

1. FiO2 changes with altitude? Sure? PAO2 does because of barometric pressure. 2. Does gravity explains the barometric pressure? Its true that distance diminish the force. But the taller column of air above a person in sea level its actually why this happens. Higher you go, shorter that column is... so less pressure.

@MedicosisPerfectionalis

3 жыл бұрын

FiO2 does NOT change with altitude. I made a mistake.

@Blackeagleglef2

3 жыл бұрын

Such honest open answer, makes me trully admire you. Thanks. Will follow.

still didnt understand why high altitude causes cerebral edema. Hypoxia in the lung causes shunting, in the brain too?

@soul832006

4 жыл бұрын

Think about the mechanism of action in edema. Fluid is forced out of blood vessels through interstitial spaces. Increasing hypoxia causes the vessels to vasoconstrict. The squeezing of the blood vessels increases pressure and leads to more fluids squeezing through. EDIT: I left out an important detail. Decreasing oxygen normally results in vasodilation to compensate. But here it cannot occur because there is insufficient oxygen available. Rising CO2 causes acidosis. Acidic environment leads to vasoconstriction. Increased pressure inside the vessels relative to surrounding tissue causes a net flow of fluid into the surrounding tissues such as the intracranial space. Hence HACE occurs. Capillaries are tiny vessels that are deliberately "leaky" to allow capillary filtration of plasma etc. That's important for blood filtration. With that in mind, it is easy to conceptualize how increased pressure from vasoconstriction leads to more fluids being pushed into surrounding tissue. The brain detects the decreased oxygen (specifically the medulla oblongata). It signals the lungs to compensate with hyperventilation. The medulla oblongata also sends out epinephrine and norepinephrine which signals blood vessels to vasoconstrict through adrenergic receptors on the vessel surface smooth muscle. This causes a release of calcium which activate the myosin chains and causes the contraction. Not sure what you meant by shunting. I was curious about the role of RAAS but that doesn't kick in during the initial acute period of AMS? I found some journal articles suggesting individuals can be susceptible to cardiovascular complications arising from incorrect activation of RAAS during acclimitisation.

The way he kept saying baabbbyyy

@MedicosisPerfectionalis

2 жыл бұрын

Haha 😆

Can you do a teaching video on carbon monoxide poisoning?

@MedicosisPerfectionalis

3 жыл бұрын

I already did...Watch it here: kzread.info/dash/bejne/aJ2to6qeeJrUeMo.html/

Thanks baby

@MedicosisPerfectionalis

4 жыл бұрын

My pleasure 😇

Sp02?

Very nice baby

Got my physiology final exam tomorrow lol

@MedicosisPerfectionalis

2 жыл бұрын

Good luck 🍀

First big error - there is no less oxygen on higher altitudes!! The amount of oxygen in atmosphere remains the same no matter how high it is, it's always 21% of air

@MedicosisPerfectionalis

Жыл бұрын

Yes, FiO2 doesn’t change, but PiO2 does.

"and u r that blue idiot on the top" 😂😂🤣🤣

@MedicosisPerfectionalis

2 жыл бұрын

Just joking 🙃

@ThePrsBee

2 жыл бұрын

@@MedicosisPerfectionalis i knooow 😄🤓 was funny 😍 what’s your specialty? (im “no pain, no pain” 😎…. having my spec-exam in December 🤯)

Does hypovolemia effects gait too?

@MedicosisPerfectionalis

3 жыл бұрын

It depends! If there is serum sodium anomalies, then it’s possible!

@fatimahayssam120

3 жыл бұрын

Thank you Dr ❤️ i love your channel and vibes🤗

Why edema occur in brain , there is vasodilation in brain right due to hypoxia?

@Carbon12r

4 жыл бұрын

Because vasodilation within the brain from the hypoxia ant the relative waste concentrations will cause vasodilation, which increases flow to the organs, in this case the brain

@mariothrowsfireballsuntitl1841

4 жыл бұрын

@@Carbon12r which is not what medicosis perfictionalis said

@mariothrowsfireballsuntitl1841

4 жыл бұрын

Sujith it's for an another reason. It's because when the ↑pH in the brain the the cerebral vessels constrict. Vice versa when the ↓pH in the brain the cerebral vessels dilate to get rid of the H+

@Carbon12r

4 жыл бұрын

@@mariothrowsfireballsuntitl1841 u basically said the same thing as I did. Accumuli of co2 causes acidosis and also a direct effect of hypoxia is lactic acidosis (i just put them all as waste products)

@mariothrowsfireballsuntitl1841

4 жыл бұрын

@@Carbon12r In every artery there is vasodilatation because of hypoxia and waste products. But the cerebral vessels are especially sensitive to acidosis

Why did I not see this person before???

@MedicosisPerfectionalis

4 жыл бұрын

Nice to meet you 😊😊

@mariejannlorrainelomarda2951

4 жыл бұрын

@@MedicosisPerfectionalis needed you when I was studying😭. It is okay this will help me study for my licensure exam😊

How to increase EPO ?

@MedicosisPerfectionalis

3 жыл бұрын

Why do you want to increase it?

Yo baby!

Its so gud honeyy😘

@MedicosisPerfectionalis

3 жыл бұрын

Thank you so much 😊

Flatearthers triggered in under two minutes

@MedicosisPerfectionalis

4 жыл бұрын

😁😁

آخرتها طلعت طعمية 🙂 امزح 😂😂😂😂 مجهود كبير والله ❤❤

@MedicosisPerfectionalis

3 жыл бұрын

Thank you so much 😊

9:40

“Edema Baby!” Yeas my way to “freakin’” learn !

@MedicosisPerfectionalis

4 жыл бұрын

Awesome 👏 Can you please help me by sharing?

This guy is sweet AF

Are you gipty bro 🇪🇬?

Yes, the rich people need to stop trying to climb Mt Everest. Your money won't change your physiology. Also, good job sneaking those jokes in. 😉

@MedicosisPerfectionalis

5 жыл бұрын

Hey Jennie...It's been a while since your last comment...How are you?

HASHTAG PHYSICS BABY

@MedicosisPerfectionalis

4 жыл бұрын

Yup 🤣

NERDDDDDDDDDDDDDDD

@MedicosisPerfectionalis

4 жыл бұрын

😁😁