A Deep Dive into Hepatitis C

Have you ever thought about the effects Hepatitis C (HCV) may have on individuals? Did you ever think about whether or not the disease can be fatal? Be sure to watch this video to make sure you find out the molecular mechanisms of the disease, symptoms, and methods of transmission in place. This video will give you insight of statistics in Canada as well as globally on cure rate, survival rate, and death rates of HCV.
Kindly click the following link for the video transcript with timestamps:
docs.google.com/document/d/12... dit?usp=sharing
This video was made by McMaster Demystifying Medicine students: Abdel-Rahman Mohamed-El Faki, Maiura Muralitharan, and Mansi Patel in collaboration with the McMaster Demystifying Medicine Program.
Copyright McMaster University 2020
References:
1. Canada, P. (2018, June 07). Government of Canada. Retrieved November 08, 2020, from
www.canada.ca/en/public-healt... able-disease-report-ccdr/monthly-issue/2018-44/issue-7-8-july-5-2018/article-7-hepatitis- c-canada-2018-infographic.html
2. Canada, P. (2020, August 14). Government of Canada. Retrieved November 08, 2020, from www.canada.ca/en/public-healt...
3. Commissioner, O. (n.d.). Hepatitis C Treatments Give Patients More Options. Retrieved November 08, 2020, from www.fda.gov/consumers/consume... more-options
4. Carrat, F., Fontaine, H., Dorival, C., Simony, M., Diallo, A., Hezode, C., ... & Zoulim, F. (2019). Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study. ​The Lancet,​ ​393​(10179), 1453-1464. doi: doi.org/10.1016/S0140-6736(18...
5. Gale, M., Blakely, C. M., Kwieciszewski, B., Tan, S. L., Dossett, M., Tang, N. M., ... & Katze, M. G. (1998). Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. ​Molecular and cellular biology​,
18(​ 9), 5208-5218. doi: 10.1128/MCB.18.9.5208
6. Ghany, M. G., Marks, K. M., Morgan, T. R., Wyles, D. L., Aronsohn, A. I., Bhattacharya, D., ... & Heller, T. (2019). Hepatitis C guidance 2019 update: AASLD-IDSA recommendations for testing, managing, and treating hepatitis C virus infection. Hepatology​, ​71​(2), 686-721. doi: 10.1002/hep.31060
7. Hepatitis C Symptoms. Diagnosing Hepatitis C - ALF. (2020, March 10). Retrieved
November 08, 2020, from liverfoundation.org/for-patie... gnosing-hepatitis-c/
8. Hepatitis C Treatment. Treatment for Hepatitis C Info - ALF. (2020, April 13). Retrieved November 08, 2020, from liverfoundation.org/for-patie... ting-hepatitis-c/
9. National Progress Report 2025 Goal: Reduce reported rate of hepatitis C-related deaths by ≥20%. (2020, August 11). Retrieved November 08, 2020, from www.cdc.gov/hepatitis/policy/...
10. Khatun, M., & Ray, R. B. (2019). Mechanisms underlying hepatitis C Virus-associated hepatic fibrosis. ​Cells,​ ​8(​ 10), 1249. doi:​ ​doi.org/10.3390/cells8101249
11. Owens, D. K., Davidson, K. W., Krist, A. H., Barry, M. J., Cabana, M., Caughey, A. B., ... & Ogedegbe, G. (2020). Screening for hepatitis C virus infection in adolescents and adults: US Preventive Services Task Force recommendation statement. ​Jama​, ​323​(10), 970-975. doi: 10.1001/jama.2020.1123
12. Schillie, S., Wester, C., Osborne, M., Wesolowski, L., & Ryerson, A. B. (2020). CDC recommendations for hepatitis C screening among adults-United States, 2020. ​MMWR Recommendations and Reports​, ​69(​ 2), 1. doi: 10.15585/mmwr.rr6902a1
13. van de Laar, T. J., van der Bij, A. K., Prins, M., Bruisten, S. M., Brinkman, K., Ruys, T. A., ... & Jurriaans, S. (2007). Increase in HCV incidence among men who have sex with men in Amsterdam most likely caused by sexual transmission. ​The Journal of infectious diseases,​ ​196(​ 2), 230-238. doi: ​doi.org/10.1086/518796
14. Vescovo, T., Refolo, G., Vitagliano, G., Fimia, G. M., & Piacentini, M. (2016). Molecular mechanisms of hepatitis C virus-induced hepatocellular carcinoma. ​Clinical Microbiology and Infection​, ​22(​ 10), 853-861. doi: ​doi.org/10.1016/j.cmi.2016.07...
15. Zeisel, M. B., Fofana, I., Fafi-Kremer, S., & Baumert, T. F. (2011). Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. ​Journal of hepatology​, ​54​(3), 566-576. doi: ​doi.org/10.1016/j.jhep.2010.1...
Credits:
The HCV life cycle animations were adapted from
• Hepatitis C Virus Life...

Пікірлер: 61

  • @MarkFox88
    @MarkFox88 Жыл бұрын

    I have been taking Zepatir for 12 weeks after testing positive during my PrEP check up. A miraculous drug. Now I am HCV free and the gastroenterologist assured me to be there for me in future if needed. No liver damage, my liver tests are good.

  • @anevliona6600

    @anevliona6600

    Жыл бұрын

    💛💛 take care!!

  • @MarkFox88

    @MarkFox88

    Жыл бұрын

    @@anevliona6600 Thank you 🏳️‍🌈

  • @Brendie2916

    @Brendie2916

    Жыл бұрын

    Congrats i start my mavret tomorrow im so excited

  • @MarkFox88

    @MarkFox88

    Жыл бұрын

    @@Brendie2916 Let me know please. You will notice more energy right after the first pill.

  • @desmomotodesmomoto2033

    @desmomotodesmomoto2033

    Жыл бұрын

    Any side effects?

  • @ankitachowdhury8884
    @ankitachowdhury88842 жыл бұрын

    Very helpful

  • @mayyang8350
    @mayyang83503 жыл бұрын

    Thank you for this informative video.

  • @annpoki4891

    @annpoki4891

    3 жыл бұрын

    Herpes can be treated and cured permanently but only few believe it. I was diagnosed of HSV few years ago, my doctor told me there is no permanent cure for the disease, I was given antiviral medication to reduce the outbreak of the virus, at the initial stage it was not so bad till it progressed to the end middle stage were I had difficulties going about my daily functions I was totally devastated till I saw a comment about Dr. Anii, who have used herbal medicines to cure virus like HERPES, HPV, ALS, when I contacted Dr. Anii, via email, after a few discussion, he prepared the medicine and ship it to me, when I received the herbal medicine, I took it according to his instructions, few weeks later I went to the hospital to have a blood test and the test came back negative, I was cured and free from this Virus... That is why I am sharing my testimony so that people can also contact him for help, via his email:­ dr.aniherbalhome1@gmail.com OR+2347054601960..

  • @mayyang8350

    @mayyang8350

    3 жыл бұрын

    @@annpoki4891 I am glad you are okay now. My son got a positive test result when he went to donate plasma. We since took him to a family doctor. My son's test came back negative. So glad!

  • @aimeequaifes175

    @aimeequaifes175

    Жыл бұрын

    My health was horrible because I was diagnosed with Hepatitis B and I felt like there was no hope for my health because I was told there was no cure. But today I am here to let everyone know that there is a herbal medicine to cure Hepatitis B and other diseases because I was able to get rid of my Hepatitis B with the help of Dr.Auchi on KZread channel herbal remedies..kzread.info/dron/6tA16t1IlKx1bY93lc2rcg.html ❤️❤️❤️

  • @jon.nexperiment1017
    @jon.nexperiment1017 Жыл бұрын

    Love your voice

  • @patientlywatching7775
    @patientlywatching7775 Жыл бұрын

    Itchy isn't the word.....I practically skinned myself alive it itched so badly!!!! Whew!!!! I took Epclusa and was cured thank God. 🙏

  • @fatimayeamasharka1619
    @fatimayeamasharka16193 жыл бұрын

    Alhamdulillah ❣️ Thank you 💟

  • @annpoki4891

    @annpoki4891

    3 жыл бұрын

    Herpes can be treated and cured permanently but only few believe it. I was diagnosed of HSV few years ago, my doctor told me there is no permanent cure for the disease, I was given antiviral medication to reduce the outbreak of the virus, at the initial stage it was not so bad till it progressed to the end middle stage were I had difficulties going about my daily functions I was totally devastated till I saw a comment about Dr. Anii, who have used herbal medicines to cure virus like HERPES, HPV, ALS, when I contacted Dr. Anii, via email, after a few discussion, he prepared the medicine and ship it to me, when I received the herbal medicine, I took it according to his instructions, few weeks later I went to the hospital to have a blood test and the test came back negative, I was cured and free from this Virus... That is why I am sharing my testimony so that people can also contact him for help, via his email:­ dr.aniherbalhome1@gmail.com OR+2347054601960..

  • @saravincelli1015
    @saravincelli10152 жыл бұрын

    Please add all medication treatments currently available for clients. Thank you!

  • @williamsteve2007

    @williamsteve2007

    2 жыл бұрын

    Dr Disu can cure your hepatitis with herbal medicine from Africa contact him through his KZread channel: kzread.info/dron/TReCxZdCY3jccYAIRos2tg.html

  • @letgodbetruebuteverymanali4849

    @letgodbetruebuteverymanali4849

    2 жыл бұрын

    @@williamsteve2007 Current treatment rakes in 87k.

  • @dailydoseofmedicinee
    @dailydoseofmedicinee3 жыл бұрын

    👏👏👍

  • @thomasmarry7034
    @thomasmarry70343 жыл бұрын

    With gratitude in my i want to say big thank you for healing my son. Dr. Adaze

  • @VSSEDragon3
    @VSSEDragon310 күн бұрын

    4:30 Super Doctor - Doctor Superhero, move over Dr. Fate and Dr. Strange

  • @kenantahir
    @kenantahir3 жыл бұрын

    i learnt just yesterday that i have happy titus c... but im not very happy about it!

  • @ayahmccants8847

    @ayahmccants8847

    Жыл бұрын

    You can look into Planet Yyurvedas live care pack. They seem to have helped several people heal their liver disease using herbs. Blessings and prayers for you love!

  • @Carlita119

    @Carlita119

    Жыл бұрын

    Hi what did you do about it?

  • @mr-jam3055

    @mr-jam3055

    Ай бұрын

    hey @kenantahir why did you do then after?

  • @adriannalykes1311
    @adriannalykes13112 жыл бұрын

    He'll! I want to say a special thanks to Dr Ayomede for helping me sort out the Hepatitis B permanently.

  • @patientlywatching7775
    @patientlywatching7775 Жыл бұрын

    Itchy isn't the word.....I practically skinned myself alive it itched so badly!!!! Whew!!!! I took Epclusa and was cured thank God. 🙏