2-Minute Neuroscience: Multiple Sclerosis
Ғылым және технология
Multiple sclerosis is a central nervous system disorder that can create a variety of symptoms ranging from visual disturbances to paralysis. It is characterized by damage to myelin, the insulatory material that surrounds neurons. This damage is linked to disruptions in healthy neuronal function, which are thought to lead to the symptoms of the disease. Most researchers believe the myelin damage that occurs in multiple sclerosis is due to the cells of the immune system targeting myelin. Thus, most of the treatments for multiple sclerosis involve drugs that suppress the immune response in some way.
The MRI image in this video is courtesy of VoiceOfReason at English Wikipedia and can be seen here: upload.wikimedia.org/wikipedi...
TRANSCRIPT:
Welcome to 2 minute neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less. In this installment I will discuss multiple sclerosis.
Multiple sclerosis, or MS, is a central nervous system disorder that involves the abrupt appearance of neurological symptoms, which usually occur for the first time between the ages of 20 and 50. The symptoms of MS vary from person to person, and almost any nervous system function can be disrupted in the disease. The most common initial symptoms involve visual disturbances, abnormal sensations, and weakness. The causes of the disease are not fully understood and are thought to involve genetic and environmental factors.
Multiple sclerosis is characterized by damage to the myelin sheaths surrounding the axons of neurons in the central nervous system. This myelin damage disrupts the conduction of action potentials along these axons, which is thought to cause many of the symptoms of the disease. The myelin damage can also lead to the deterioration of axons. The brains of MS patients can contain evidence of this damage in the form of plaques or lesions that are visible with some types of neuroimaging.
The reason these attacks on a patient’s myelin occur is not fully understood, but the damage in MS is most commonly attributed to an autoimmune attack. According to this hypothesis, the immune system in a patient with MS targets myelin, treating it as foreign. This autoimmune attack and the associated inflammatory response leads to damage to myelin, axons, and glial cells. What prompts the autoimmune attack is not known, however, and some have argued that MS is caused by a persistent infection instead.
Either way, MS seems to involve excessive immune system activation in some respect, and the drugs that have proven most successful in treating it act to reduce inflammatory or other immune responses.
REFERENCE:
Purves D, Augustine GJ, Fitzpatrick D, Hall WC, Lamantia AS, McNamara JO, White LE. Neuroscience. 4th ed. Sunderland, MA. Sinauer Associates; 2008.
Пікірлер: 107
As a nursing student, my friends and I REALLY appreciate these videos for quick overviews while studying!!! Thank you so much!
@neurochallenged
6 жыл бұрын
I'm very glad they're helpful to you! Thanks for watching!
@sharehandanaf3200
2 жыл бұрын
Hd
@sharehandanaf3200
2 жыл бұрын
@@neurochallenged child u
@sharehandanaf3200
2 жыл бұрын
O
Excellent 2 minute video!! My first ms 'attack' was 30 yrs ago. Just strange how one's body attacks its nervous system.
@WalkofLifewithSumit
3 жыл бұрын
I have MS too. This has inspired me to start my owm KZread journey. Please check out and support.
@Okie343
2 жыл бұрын
Most of the time it is a low B12 at the tissue level causing the problems and it's misdiagnosed as MS. When B12 gets low at the tissue level it causes methylmalonic acid to elevate and this acid eats the myelin sheaths from the nerves. You need a methylmalonic acid blood test to determine the B12 tissue level. A normal B12 blood test won't suffice. Good luck
@tbsmultitask-side6104
2 жыл бұрын
Are you fine now
@CHRISRepAZ
Жыл бұрын
@@Okie343 yes many years ago I had MMA test and it was normal. I've had serum b12 levels done many times. Always normal.
@CHRISRepAZ
Жыл бұрын
@@tbsmultitask-side6104 I'm okay. I do need to use a walker outside especially when it's hot out.
hey! i want to give u a big thumbs up, you are covering very interesting subjects and educate people who are not accustomed to neuroscience, you raise awareness towards our need to understand better our brain and how we work. i enjoy your vids, keep it up( from a hopefully future medicine student)
Well done making all of those mini tutorials videos! Very clear explanations! Thanks!
Just got home from school. We had a neuro exam and the topic about multiple sclerosis came out. How I wish I already finish watching this vid before taking my exam 😭
Beautifully done. Great voice and knowledge. Thank you . Keep up the good work.
Sharing this in a global educational MS group. ❤️ excellent
Awesome and quick! Thanks!
As somebody living with MS good luck having your family and friends understand the struggle. But you look just fine! lol
@jessicamichelle1025
Жыл бұрын
Exactly!
@bltvd
6 ай бұрын
I think the problem is that more often than not woman with “MS” think it means they can be super lazy.
@euphobic1
Ай бұрын
it was harder to get Dr's to listen. I didn't know what it was but I'd go to the Drs. Binding migraines, I need to suck it up & take aspirin. weeks of vertigo? I must be making it up because of my bipolar disorder. I had to tell the Dr I think I had a stroke to get an MRI & after 14 years I got a clear answer, MS. I cried a little not because of it but finally knowing what was wrong.
@Devil66652
11 күн бұрын
I lost my mom to MS 2 years ago n it hurts me so bad
Good vid. Thanks!
15 yor Male and I was informed that I have this. Can someone tell me to not worry and that it's going to be ok? I'm really nervous man
@herbal_doctor_isiramen
2 жыл бұрын
Good day, Am great DR ISIRAMEN (HERBAL DOCTOR🌿) who knows every roots and herbs🌿 to cure asthma, cancer, HIV/AIDS, herpes,Diabetes and any kinds of human diseases, infection (virus)!
@nancycarlos5695
2 жыл бұрын
All thanks to Dr.Auchi on KZread for cured me completely from Multiple Sclerosis diseases, if you are there suffering from Multiple Sclerosis disease you can kind visit is KZread channel kzread.info/dron/6tA16t1IlKx1bY93lc2rcg.html for a solution✅✅🙏🙏
@lakea.6218
2 жыл бұрын
Do you have amalgam fillings in your mouth?
@AZmystic1977
Жыл бұрын
My son is 26 and was just diagnosed 2 weeks ago so he is with you. You are not alone
@rotomwash0355
Жыл бұрын
You're young. Save your money and do medical tourism. Go to South America and get stem cell treatments.
Thank you!
Thank you
it was helpful. i was wondering how mine works :Dthank you
Thanks from a physical therapy student!
My older brother suffers from MS. He’s been fighting it for a while. Wish I was strong like him.
When I was first diagnosed, I was worried.
What if you have a singular Sclerosis?
I searched this up because of a spotify artist and its really depressing, anybody who has it does not deserve it, its a scary thing to think about
I had a ton of confusion in the beginning too - probably the 40 legions 🤦🏻♀️
@nancycarlos5695
2 жыл бұрын
All thanks to Dr.Auchi on KZread for cured me completely from Multiple Sclerosis diseases, if you are there suffering from Multiple Sclerosis disease you can kind visit is KZread channel kzread.info/dron/6tA16t1IlKx1bY93lc2rcg.html for a solution✅✅🙏🙏
I have symptoms of ms but my doctor is giving me antidepressants. The symptoms are not occuring but when I don't eat medicines for 1-2 days the sysmptoms reappear. Please tell if depression has similar symptoms like ms
@sharonnicholson8547
Ай бұрын
I have Ms & its not like depression.
is the multiple system atrphy us the same?
@Crush-hm5dp
2 жыл бұрын
Inbox doctor Akhigbe on Whats app for cure
@Crush-hm5dp
2 жыл бұрын
Message him on Whats app
@Crush-hm5dp
2 жыл бұрын
✝️ 2348140126449⏭⏭🇳🇬❤️❤️❤️❤️
Hello I am 12 and think I have multiple sclerosis. . . :( I’m going to a dr so I’ll come back and tell you if I have it or not
@sheenboi5440
3 жыл бұрын
What was the outcome
@nancycarlos5695
2 жыл бұрын
All thanks to Dr.Auchi on KZread for cured me completely from Multiple Sclerosis diseases, if you are there suffering from Multiple Sclerosis disease you can kind visit is KZread channel kzread.info/dron/6tA16t1IlKx1bY93lc2rcg.html for a solution✅✅🙏🙏
@cacosta560
Жыл бұрын
What did the doctor say? What symptoms did you have?
Someone please tell me what’s the best thing my mother can take because she’s taking these injections and their doing her no good
@TeosamEm3
9 ай бұрын
GET YOUR TO EAT Moringo leaves put in a salad cook it in food fry i egg any use in tea just google Moringa
@Beannin
9 ай бұрын
MS patient of 5 years here. I am personally really happy with Ocrevus, a high efficiency drug administered via IV twice a year. Your mom should talk to her neurologist about her options. And for the love of all that is holy: STAY AWAY from all the strange "natural" cures, none of them work. We cannot cure MS (yet) but researchers all over the world are working on it.
Do you have ms?
@shaniceanderson
Жыл бұрын
My skin looks like yours
hep?
Person below think I will make it. BE POSITIVE
I have been ill for almost 10 years, I came to the conclusion that I am developing so slowly due to daily sports such things as a horizontal bar, a press wheel, a Kuznetsov applicator.available to everyone
MHV can cause MS
Had these symptoms until I did a 90 day juice fast. We can heal ourselves. Do not turn to pills.
@Beannin
9 ай бұрын
Then you do not have MS and never had it. There has not been a single documented case of anyone anywhere in the world being cured of MS.
@gabherreria1841
3 ай бұрын
Symptoms or diagnosis? You just cant say that when you're only just experiencing symptoms and not the diagnosis. Its completely unrelated
@freee002
3 ай бұрын
@@gabherreria1841 over a year later and still no longer have these symptoms. Believe what you want. I'm not here to convince anyone 🤷♀️
we know now that it is highly associated with epstein-barr.
was soll dieser aal
@hartmjo1
2 жыл бұрын
?