18.3 EAS Ortho-Para Directors vs EAS Meta Directors | Organic Chemistry
Chad gives a thorough presentation on Ortho-Para directors and Meta Directors in EAS Reactions. He begins by identifying electron-donating groups and electron-withdrawing groups and showing how electron-donating groups are activating groups in EAS reactions, whereas electron-withdrawing groups are deactivating. He provides a table of benzene substituents which can be used to predict relative rates of reactivity in EAS reactions. Chad shows how electron-donating groups stabilize the sigma complex intermediate in EAS reactions, whereas electron-withdrawing groups destabilize the sigma complex.
He then shows how electron-donating groups stabilize the sigma complex most when substitution occurs at the ortho and para positions explaining why they are ortho-para directors. He then shows how most electron-withdrawing groups destabilize the sigma complex the most when substitution occurs at the ortho and para positions explaining why they are meta directors. He also points out how halogens are the exceptions in that they are ortho-para directors though electron-withdrawing groups.
Finally, Chad shows several examples of how to predict the products of EAS reactions with substituted benzenes.
I've created an organic chemistry page that organizes all my videos by chapter - just an easier way for you to watch my KZread videos. Check it out at www.chadsprep.com/chads-organic-chemistry-videos/
00:00 Lesson Introduction
00:54 EAS Activating Groups vs EAS Deactivating Groups
07:32 EAS Electron-Donating Groups | EAS Ortho-Para Directors
19:46 Halogens: EAS Electron-Withdrawing Groups and EAS Ortho-Para Directors
22:23 EAS Meta Directors
25:37 Special Reactivity of Aminobenzenes in EAS Reactions
28:54 EAS Predicting the Products Example #1
30:54 EAS Predicting the Products Example #2
32:38 EAS Predicting the Products Example #3
33:24 EAS Predicting the Products Example #4
36:28 EAS Predicting the Products Example #5
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Chad -- I don't often comment but what you've done here deserves praise. To offer this (for free, I might add) is a work of utmost selflessness. I freakin' admire you for it, man! Keep it up
@ChadsPrep
2 жыл бұрын
Glad you found the channel, Nick - Happy Studying!
I have to say that, I literally passed my previous orgo. chem. because of your videos. I learned nothing from my professor. I'm studying through your channel this semester too. Appreciate your efforts. You're the best!
@ChadsPrep
2 жыл бұрын
Glad the channel is helping you so much, aya alsalih - Hope you do well in your studies!
This channel is top tier
@ChadsPrep
2 жыл бұрын
Thank you, Cassie!
@caseyjang
Жыл бұрын
I second this comment
You're the best! You're explaining every single detail clearly! Keep it going
@ChadsPrep
3 жыл бұрын
Thanks, Nihad!
Chad, you are a lifesaver my guy! Thank you, thank you, thank you for your guidance through all these concepts. Cannot thank you enough!
@ChadsPrep
5 ай бұрын
Glad the channel is helping so much!
This channel is top tier! Thank you for the efforts you put in making O. Chem understandable.
@ChadsPrep
Жыл бұрын
You're welcome and Thank You!
I got the highest grade in my class, on my midterm because of these incredible videos! I appreciate these free resources, you're the best. :)
@ChadsPrep
2 жыл бұрын
Kudos, Emily - Good for you and all your hard work paying off!
I'm learning this right now, thank you so much for the tips! Definitely understand this more!
@ChadsPrep
8 ай бұрын
Glad it was helpful!
How could I thank you 😭💛💛 I have really understood every detail that I've needed 💙✨️
@ChadsPrep
Жыл бұрын
Great to hear!
SO HELPFUL AND CLEAR!!
@ChadsPrep
3 ай бұрын
Excellent!
WIsh I found you sooner, got an exam tomorrow and this is all really scary stuff, but you've helped a lot! God bless!
@ChadsPrep
2 жыл бұрын
Better late than never - hope you do well on your exam!
You're amazing! You explain all these concepts so well! I'm passing organic chemistry 2 because of you : ) I was really apprehensive about taking it in the summer but everything is going really good so far ; )
@ChadsPrep
Жыл бұрын
Glad the channel is helping you - Happy Studying!
Amazing job! This makes sense to me know
@ChadsPrep
2 жыл бұрын
Glad to hear it, Soso Rob!
Thank You for making it so easy!
@ChadsPrep
Жыл бұрын
You're welcome.
Thank you, Mr.Chad.
@ChadsPrep
2 жыл бұрын
You're welcome, AK!
you are saving my life right now in ochem 2.
@ChadsPrep
8 ай бұрын
Glad the channel is helping you!
Thank you, this was a great lesson
@ChadsPrep
8 ай бұрын
You're welcome
Excellent Tutor!
@ChadsPrep
Жыл бұрын
Thank you.
thank youuuuuuuu you made that clear ♥✨🎉
@ChadsPrep
8 ай бұрын
Youuuuuuu're Welcome!
Thank you so much!
@ChadsPrep
3 жыл бұрын
You're welcome, Hailey!
Thank you so much sir!
@ChadsPrep
Жыл бұрын
You're welcome!
amazing
@ChadsPrep
2 ай бұрын
Thank you
12:31 can you explain more specifically why the attack of E+ makes the metha carbon becomes more positive please. thank you a lot
Thanks a lot
@ChadsPrep
2 жыл бұрын
Most welcome, Laila.
Weirdly got this concept delivered before the five EAS types
@ChadsPrep
Жыл бұрын
Hope you found it helpful Luke! :)
u saved me for this orgo test next week i am literally crying with joy cuz all of this wasnt making sense.
@ChadsPrep
6 ай бұрын
Glad the channel is helping you!
which among the following is the most deactivating group aromatic substitution reaction (Please rank the alternatives from strongest to weakest)? A. -NR3 B. -SO3H C. -NO2 D. -CN.
Do electron withdrawing groups destabilize the benzenes in EAS as a result of withdrawing the electron density (and therefore making the conj base of a phenol, for instance, more stable and therefore worse as a nucleophile)? Or is it because the electron withdrawing effects destabilize the carbocation intermediate?
@ChadsPrep
5 ай бұрын
Both!!! Very nice reasoning on both parts. Electron withdrawing groups lower the energy of electrons making 😊nucleophiles more stable and less reactive. But the sigma complex, i.e. the carbocation intermediate in EAS reactions, which is already electron-deficient, is destabilized by these electron-withdrawing groups. Essentially, exactly what you said!
@user-qs8he1ml3k
5 ай бұрын
Appreciate the quick response and thanks. Your videos are actually going to make my career, I've seen basically all of them@@ChadsPrep
@ChadsPrep
5 ай бұрын
That's awesome and I know you are going to be an asset in any career you pursue :)
isn't phenol supposed to have 5 resonance structures?
@max3eey
8 ай бұрын
Yes, but not all of them are equally as stable. The lower energy ones are preferred for EAS.
When did Johnny is interested in chem 🌝
@ChadsPrep
Жыл бұрын
Chad's the name - welcome to the channel!
I love uuuuuuu
@ChadsPrep
3 ай бұрын
Glad the channel is helping you.